Sionna Therapeutics, Inc.
    Insider Ownership

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    Current Insider Ownership

    Coulter James G10% Owner
    Common Stock
    Jan 22, 2026
    6,494,962
    14.43
    247,328,153
    Winkelried Jon10% Owner
    Common Stock
    Jan 22, 2026
    6,494,962
    14.43
    247,328,153
    Tpg Gp A, Llc10% Owner
    Common Stock
    Jan 22, 2026
    6,494,962
    14.43
    247,328,153
    Orbimed Advisors LlcDirector
    Common Stock
    Feb 3, 2026
    3,530,702
    7.85
    134,449,132
    Thompson Peter A.Director
    Common StockNon-Qualified Stock Option (right to buy)
    Feb 3, 2026Jun 12, 2025
    3,530,70219,959
    7.850.04
    134,449,132760,039
    Orbimed Capital Gp Viii LlcDirector
    Common Stock
    Feb 3, 2026
    3,530,702
    7.85
    134,449,132
    Atlas Venture Fund Xi, L.P.10% Owner
    Common Stock
    Feb 10, 2025
    807,727
    1.80
    30,758,244
    Atlas Venture Associates Xi, Llc10% Owner
    Common Stock
    Feb 10, 2025
    807,727
    1.80
    30,758,244
    Atlas Venture Associates Xi, L.P.10% Owner
    Common Stock
    Feb 10, 2025
    807,727
    1.80
    30,758,244
    Atlas Venture Opportunity Fund Ii, L.P.10% Owner
    Common Stock
    Feb 10, 2025
    807,727
    1.80
    30,758,244
    Atlas Venture Associates Opportunity Ii, Llc10% Owner
    Common Stock
    Feb 10, 2025
    807,727
    1.80
    30,758,244
    Atlas Venture Associates Opportunity Ii, Lp10% Owner
    Common Stock
    Feb 10, 2025
    807,727
    1.80
    30,758,244
    Booth BruceDirector
    Common StockNon-Qualified Stock Option (right to buy)
    Oct 21, 2025Jun 12, 2025
    686,56719,959
    1.530.04
    26,144,471760,039
    Cloonan MichaelPresident & CEO
    Common StockNon-Qualified Stock Option (right to buy)Stock Option (Right to Buy)
    Oct 21, 2025Jan 2, 2026Feb 6, 2025
    547,343489,242450,252
    1.221.091.00
    20,842,82118,630,33517,145,596
    Ra Capital Healthcare Fund LpDirector
    Common Stock
    Nov 21, 2025
    159,033
    0.35
    6,055,977
    Ra Capital Management, L.P.Director
    Common Stock
    Nov 21, 2025
    159,033
    0.35
    6,055,977
    Kolchinsky PeterDirector
    Common Stock
    Nov 21, 2025
    159,033
    0.35
    6,055,977
    Shah Rajeev M.Director
    Common Stock
    Nov 21, 2025
    159,033
    0.35
    6,055,977
    Ra Capital Nexus Fund, L.P.Director
    Common Stock
    Nov 21, 2025
    159,033
    0.35
    6,055,977
    Ra Capital Nexus Fund Iii, L.P.Director
    Common Stock
    Nov 21, 2025
    159,033
    0.35
    6,055,977
    Ridloff ElenaCFO & Head of Corp. Dev.
    Common StockNon-Qualified Stock Option (right to buy)Stock Option (Right to Buy)
    Sep 2, 2025Jan 2, 2026Feb 6, 2025
    38,532165,440157,820
    0.090.370.35
    1,467,2996,299,9556,009,786
    Clancy Paul JDirector
    Non-Qualified Stock Option (right to buy)
    Jun 12, 2025
    19,959
    0.04
    760,039
    Stelzer LaurieDirector
    Non-Qualified Stock Option (right to buy)
    Jun 12, 2025
    19,959
    0.04
    760,039
    Resnick JoshuaDirector
    Non-Qualified Stock Option (right to buy)
    Jun 12, 2025
    19,959
    0.04
    760,039
    Viney Joanne L.Director
    Non-Qualified Stock Option (right to buy)Stock Option (Right to Buy)
    Jun 12, 2025Feb 6, 2025
    19,95939,919
    0.040.09
    760,0391,520,116
    Fleming Harold EdwardDirector
    Non-Qualified Stock Option (right to buy)
    Jun 12, 2025
    19,959
    0.04
    760,039
    Ruddy Marcella K.Director
    Non-Qualified Stock Option (right to buy)Stock Option (Right to Buy)
    Jun 12, 2025Feb 6, 2025
    19,95939,919
    0.040.09
    760,0391,520,116
    Mckee CharlotteChief Medical Officer
    Non-Qualified Stock Option (right to buy)Stock Option (Right to Buy)
    Jan 2, 2026Feb 6, 2025
    155,700148,536
    0.350.33
    5,929,0565,656,251
    Fitzpatrick JenniferChief Legal Officer
    Non-Qualified Stock Option (right to buy)
    Mar 5, 2026
    154,075
    0.34
    5,867,176
    Beer Caroline StarkChief Business Officer
    Non-Qualified Stock Option (right to buy)
    Jan 2, 2026
    394,340
    0.88
    15,016,467

    Insider Trading Trends

    Insider Transactions

    Voluntary Buys vs Sells

    Historical Insider Trading (3-Years)

    10b5-1

    Fitzpatrick JenniferNQSOCommon StockNoYesExercise/Conversion
    DISPOSE
    M
    		6.11-10,25062,62850,935Mar 5, 2026
    Fitzpatrick JenniferCommon StockNoYesExercise/Conversion
    ACQUIRE
    M
    		6.11+10,25062,62810,250Mar 5, 2026
    Fitzpatrick JenniferCommon StockNoYesSell
    DISPOSE
    S
    		33.86-10,250347,0190Mar 5, 2026
    Orbimed Capital Gp Viii LlcCommon StockYesNoSell
    DISPOSE
    S
    		44.58-29,0631,295,6293,530,702Feb 3, 2026
    Orbimed Advisors LlcCommon StockYesNoSell
    DISPOSE
    S
    		44.58-29,0631,295,6293,530,702Feb 3, 2026
    Thompson Peter A.Common StockYesNoSell
    DISPOSE
    S
    		44.58-29,0631,295,6293,530,702Feb 3, 2026
    Orbimed Capital Gp Viii LlcCommon StockYesNoSell
    DISPOSE
    S
    		44.57-1,89084,2373,559,765Feb 2, 2026
    Thompson Peter A.Common StockYesNoSell
    DISPOSE
    S
    		44.57-1,89084,2373,559,765Feb 2, 2026
    Orbimed Advisors LlcCommon StockYesNoSell
    DISPOSE
    S
    		44.57-1,89084,2373,559,765Feb 2, 2026
    Coulter James GCommon StockYesNoSell
    DISPOSE
    S
    		40.00-250,00010,000,0006,494,962Jan 22, 2026
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    Sionna Therapeutics, Inc. Insider Trading and Ownership | CapEdge