UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, DC 20549


FORM 10-K


xSANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

 For the fiscal year ended August 31, 20102012

or

or

o£TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

 For the transition period from _________ to _________

Commission file number: 001-32046


Simulations Plus, Inc.

(Exact name of registrant as specified in its charter)


California

(State or other jurisdiction of incorporation or organization)

95-4595609

 (I.R.S.

(I.R.S. Employer Identification No.)

42505 Tenth Street West

Lancaster, CA 93534-7059

(Address of principal executive offices including zip code)

(661) 723-7723

(Registrant’s telephone number, including area code)


SECURITIES REGISTERED PURSUANT TO SECTION 12(b) OF THE ACT:


Title of Each Class

Common Stock, par value $0.001 per share

Name of Each Exchange on Which Registered

NASDAQ Stock Market LLC



SECURITIES REGISTERED UNDERPURSUANT TO SECTION 12(G) OF THE ACT: NONE


Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act.

YesYes o£ NoxS


Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act.

YesYes o£ NoxS


Indicate by check mark whether the registrant (1) filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filings requirements for the past 90 days.

YesYes xS Noo£


Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site,Website, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).

YesYes oS Noo£


Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K (§229.405) is not contained herein, and will not be contained, to the best of registrant'sregistrant’s knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-K or any amendment to this Form 10-K.o£


Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of “large accelerated filer,” “accelerated filer,”filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act (Check one):

o£  Large accelerated filer
o£  Accelerated filer
o£  Non-accelerated filer (Do not check if a smaller reporting company)
xS  Smaller reporting company

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes [   ]£  No [X]

S

The aggregate market value of the registrant'sregistrant’s common stock held by non-affiliates of the registrant as of February 26, 2010,29, 2012, based upon the closing price of the common stock as reported by The Nasdaq Stock Market on such date, was approximately $15,211,000.$38,035,604. This calculation does not reflect a determination that persons are affiliates for any other purposes.

As of November 26, 2010, 15,501,97913, 2012, 15,927,806 shares of the registrant’s common stock, par value $0.001 per share were outstanding, and no shares of preferred stock were outstanding.

DOCUMENTS INCORPORATED BY REFERENCE

Certain portions of the definitive Proxy Statement to be delivered to shareholders in connection with the 20112013 Annual Meeting of Shareholders are incorporated by reference into Part III of this Form 10-K.




10-K to be filed with the Securities and Exchange Commission within 120 days after the close of the fiscal year covered by this annual report.

The Exhibit Index (Item 15) lists several documents incorporated by reference.

 

 



Simulations Plus, Inc.

FORM 10-K

For the Fiscal Year Ended August 31, 2010




2012

Table of Contents



  Page
PART I  
   
Item 1Business1
Item 1ARisk Factors  118
Item 1BUnresolved Staff Comments  118
Item 2Properties118
Item 3Legal Proceedings  119
Item 4ReservedMine Safety Disclosures  12
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PART II  
   
Item 5Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities129
Item 6Selected Financial Data  1310
Item 7Management’s Discussion and Analysis of Financial Condition and Results of Operations1411
Item 7AQuantitative and Qualitative Disclosures About Market Risk2120
Item 8Financial Statements and Supplementary Data2220
Item 9Changes in and Disagreements With Accountants on Accounting and Financial Disclosure  2220
Item 9AControls and Procedures  2220
Item 9BOther Information2321
   
   
PART III  
   
Item 10Directors, Executive Officers and Corporate Governance  2321
Item 11Executive Compensation  2322
Item 12Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters2322
Item 13Certain Relationships and Related Transactions, and Director Independence2422
Item 14Principal Accounting Fees and Services2422
   
   
PART IV  
   
Item 15Exhibits, Financial Statement Schedules2422
Signatures24

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Forward-Looking Statements

This document and the documents incorporated in this document by reference contain forward-looking statements that are subject to risks and uncertainties. All statements other than statements of historical fact contained in this document and the materials accompanying this document are forward-looking statements.

The forward-looking statements are based on the beliefs of our management, as well as assumptions made by, and information currently available to, our management. Frequently, but not always, forward-looking statements are identified by the use of the future tense and by words such as “believes,” expects,” “anticipates,” “intends,” “will,” “may,” “could,” “would,” “projects,” “continues,” “estimates” or similar expressions. Forward-looking statements are not guarantees of future performance and actual results could differ materially from those indicated by the forward-looking statements. Forward-looking statements involve known and unknown risks, uncertainties, and other factors that may cause ou rour or our industry’s actual results, levels of activity, performance or achievements to be materially different from any future results, levels of activity, performance or achievements expressed or implied by the forward-looking statements.

The forward-looking statements contained or incorporated by reference in this document are forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended (“Securities Act”) and Section 21E of the Securities Exchange Act of 1934, as amended (“Exchange Act”), and are subject to the safe harbor created by the Private Securities Litigation Reform Act of 1995. These statements include declarations regarding our plans, intentions, beliefs or current expectations.

Among the important factors that could cause actual results to differ materially from those indicated by forward-looking statements are the risks and uncertainties described under “Risk Factors” in this document and in our other filings with the Securities and Exchange Commission (“SEC”).

Forward-looking statements are expressly qualified in their entirety by this cautionary statement. The forward-looking statements included in this document are made as of the date of this document and we do not undertake any obligation to update forward-looking statements to reflect new information, subsequent events or otherwise.


PART I


ITEM

Item 1 –BUSINESS


Overview of the Company
–Business

OVerview

Simulations Plus, Inc. (“Simulations Plus”, or together with Words+, Inc. (“Words+”) its wholly owned subsidiary referred to as the “Company,” “us,” “we,” or “our”), produces different types of products: Simulations Pluswhich was incorporated in California in 1996, and develops and produces software for use in pharmaceutical research and for education, as well asand provides consulting and contract research services to the pharmaceutical industry. Simulations Plus has also taken overassumed responsibility for producing a personal productivity software program called Abbreviate!, originally spun out of products for the disabled created by our former subsidiary, Words+, for the retail market. Words+, which was founded in 1981, produces computer software and specialized hardware for use by persons wi thwith disabilities. ForDuring the purposesfirst quarter of our fiscal year ended August 31, 2012, Words+ continued to refine its products for the disabled. We sold Words+, pursuant to that certain stock purchase agreement with the Prentke Romich Company of Wooster, Ohio, effective as of November 30, 2011. Words+ is now a wholly-owned subsidiary of the Prentke Romich Company. As a result of this sale, Words+ is treated as “discontinued operations” in our financial statements attached hereto. For more information regarding the Stock Purchase Agreement, please see the full text of such document we sometimes referfiled as Exhibit 10.50 to this Annual Report on Form 10-K, which is incorporated herein by reference. Also see Note 12 under the Notes to the two businesses as “Simulations Plus” when referring to the business ofFinancial Statements included in this Annual Report on Form 10-K for more information. The discussion in this Annual Report on Form 10-K will therefore focus on our ongoing operations for pharmaceutical software and services, educational software, and Abbreviate!, and “Words+” when referring to the business that is focused on assistive technologies for persons with disabilities.services.

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Simulations Plus

PRODUCTS

Products

We currently offer fourfive software products for pharmaceutical research: ADMET Predictor™, MedChem Designer™, MedChem Studio™ (formerly known as ClassPharmer™), DDDPlus™, and GastroPlus™.


We call the combination of ADMET Predictor, MedChem Studio, and MedChem Designer our ADMET Design Suite™.

ADMET Predictor™

Every drug molecule that fails in clinical trials, and every approved drug that gets withdrawn from the market, was bad from the time its structure was first drawn by a chemist or generated by a computer - they don’t become bad later in development. Expensive development activities that attempt to determine whether or not such failed molecules can become useful medicines are wasted resources. Thus, the ability to predict unsuitable characteristics of new molecules as early as possible offers the promise of avoiding costly programs that end up in late-stage failures.  Although not every failure mode can be predicted in this manner, those that can provide a means to reduce the number of failures that frequently occur after years of work and sometimes more than a billion dollars have been spent.

ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity) Predictor providesis a collection of highly sophisticated and statistically significant numerical modelscomputer program that predict various properties of chemical compounds from just their molecular structures.  Our models are built using proprietary machine learning approaches that are based primarily on artificial neural network ensembles (groups of artificial neural networks).


Having this capability means a chemist can merely draw a molecule diagram and get estimates of a wide variety of properties, even though the molecule has never existed. Drug companies continually search through millions of such “virtual”takes molecular structures as they attemptinputs and predicts over 140 different properties for them at the rate of about 200,000 compounds per hour on a laptop computer. This capability means that a pharmaceutical scientist can screen a very large number of molecules in a very short time using ADMET Predictor. The current state-of-the-art of this type of software allows identifying molecules that are sure to find new drugs. It has been estimated that there are somewhere on the order of 1062 possible drug-like molecular structures. That is such a huge number that it is difficult to comprehend. If we could evaluate a trillion molecules (1012) per second (we cannot), it would still take 1050 seconds to eval uate them all -- that’s about 10,000,000,000,000,000,000,000,000,000,000,000,000,000,000 years. The age of the universe is said to be much less than 100,000,000,000 years. Clearly, we will never be able to make and test all of them, so computerized methods are the only hope to even scratch the surface of the total “chemical space” forfail as potential pharmaceutical products.

The vast majority of drug-like molecules are not suitable as medicines for various reasons. Some have such low solubility that they will not dissolve well, some have such low permeability through cell walls that they will not be absorbed well, some degrade so quickly that they are not stable enough to have a useful shelf life, some bind to proteins (such as albumin) in blood to such a high extent that little unbound drug is available to reach the target, and many will produce a variety of adverse effects. Identification of such properties in the computer (“in silico”) enables researchers to eliminate poor compounds quickly and early before spending time and money to make them and run experiments to identify their weaknesses. Today, many potential ne w molecules can be eliminated on the basis of the properties predicted by ADMET Predictorcandidates without the need to actually makesynthesize and test them. We continue to add predictive models for additional properties to allow eliminating even more unsuitable molecules as early as possible.

Several independent studies have been published that compare the accuracyMillions of software programs like ADMET Predictor. In almost every case, ADMET Predictor has been ranked first in accuracy. The specific set of molecules used in such studies, as well as the statistics used for comparison, often favors one program over others; however, across all published studies, ADMET Predictor has been top-ranked far more than any other program.

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ADMET Predictor includes a subprogram ADMET Modeler™ as an optional module. ADMET Modeler was first released in July of 2003 as a separate product (with the name QMPRchitect™),“virtual” compounds can now be created and was integrated into ADMET Predictor in 2006. This powerful program is what we use to train our  best-in-class predictive models in ADMET Predictor. Having it in ADMET Predictor means our users can train their own proprietary models using their own data for various properties and add them to the commercial models we provide. ADMET Modeler automates the complex training process, so very high quality models are producedscreened in a small fractionday, compared to potentially months of the time once required. For example, new models are typically developed in a matter ofwork to synthesize and test a few hours once we complete the tedious effort of “cleaning up” the databases (wh ich often containhundred actual compounds. The ability to quickly eliminate obviously poor compounds in this manner enables chemists to investigate a significant number of errors). Prior to the availability of ADMET Modeler, we needed as much as three months to develop eachlarger “chemical space” in their search for new model after cleaning the database.

medicines.

Pharmaceutical companies spend enormous amounts of money conducting a wide variety of experiments on new molecules each year.year, resulting in large databases of experimental data. Using their ownthis proprietary data to build predictive models providescan provide a second return on thistheir investment; however, in the past, model building has traditionally been a tedious activity performed by specialists. WithThe ADMET Modeler subprogram that is integrated into ADMET Predictor enables scientists without model-building experience can nowto use their own experimental data to quickly create high-quality, proprietary predictive models.


models using the same powerful modeling methods we use to build our top-ranked property predictions.

We released Version 6.0 of ADMET Predictor is compatiblein April 2012. This new version incorporates a new feature that enables users to generate likely metabolites for any molecule using an embedded version of our MedChem Designer™ program. It also increases the number of predictive models for metabolism and toxicity, and refines many of our earlier predictions, which had already been top-rated in almost every published independent comparison study. In March 2010, we entered into the a royalty agreement with Enslein Research pursuant to which royalties were paid to Enslein Research from revenues on each license for the popular Pipeline Pilot™ software offeredEnslein Metabolism Module. On February 28, 2012, we agreed to buyout this royalty agreement from Enslein Research. This buyout gave us sole ownership of the intellectual property rights used in the Enslein Metabolism Module and allowed us to merge the former Enslein Metabolism Module and our Metabolite Module into a single Metabolism Module, making it easier for customers to realize the value in the combined capabilities of the two separate functions. We are also progressing with curating the scientific literature for a much larger data set for certain enzymes known as the cytochrome P450 (“CYP”) family to further enhance our predictive capabilities for metabolism. These improvements to metabolism and metabolite prediction are now also available via MedChem Designer and MedChem Studio for customers who also license ADMET Predictor.

MedChem Designer™

MedChem Designer was launched in February 2011. It was initially a molecule drawing program, or “sketcher”, but now has capabilities beyond those of other molecule drawing programs because of its integration with both MedChem Studio and ADMET Predictor. We provide MedChem Designer for free because we believe that in the long run it will help to increase demand for ADMET Predictor and MedChem Studio. Most other existing molecule drawing programs are also free. The free version includes a small set of ADMET Predictor property predictions, allowing the chemist to modify molecular structures and then see a few key properties very quickly. The chemist also sees that with a paid ADMET Predictor license, over 140 predictions would be available.

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When coupled with a license for ADMET Predictor, MedChem Designer becomes ade novo design tool for medicinal chemists. With it, they can draw one or more molecular structures, then click on the ADMET Predictor icon and have over 140 properties for each structure calculated in seconds, including our proprietary ADMET Risk™ index. ADMET Risk provides a single number that tells the chemist how many threshold values for more than 20 predicted properties were crossed (or violated) by Accelrys, Inc.. This software serveseach structure. Thus, in a single number, the chemist can instantly compare how different structural changes affect a variety of predicted properties. As chemists attempt to modify structures to improve one property, they often cause others to become unacceptable. Without ADMET Risk, the chemist would have to separately examine many key properties for each new molecule to check whether any became unacceptable as a toolresult of changing the structure. Thus, ADMET Risk lets them “see” in many dimensions at once. We believe this provides a novel and unequaled capability for new molecule design. In addition to allow chemistsaffecting the therapeutic target, there are many properties that are required for a molecule to run several different software programsbecome a drug, and ADMET Predictor can predict a large number of such properties.

We released MedChem Designer 2.0 in seriesMay 2012 with its new capabilities that show the most likely metabolites that would be produced from a parent molecule by the most dominant CYP enzymes. With this capability, the chemist can not only see predicted likely metabolites, but can also use ADMET Predictor to accomplishassess whether any of the predicted metabolites would be likely to result in unacceptable adverse effects. It is often the case that a set workflow for large numbersmolecule that could have been a good medicine is converted into a toxic metabolite that renders the original molecule dangerous or useless. This ability to predict metabolites and their properties is another way to reduce the number of molecules. In early discovery, chemists often work with hundreds of thousands or millions of “virtual” molecules – molecules that existare taken forward into development only in computer files. Chemists need to decide which few molecules from these large “libraries” should be madefail at a later stage after considerable time and tested or taken further in development. Using Pipeline Pilot with ADMET Predictor (and MedChem Studio™ – see below), perhaps in conjunction with other software products, chemists can create and screen very large libraries faster and more efficiently than by running each progra m by itself. Perhaps the most important aspect of this process is obtaining accurate property predictions for new molecular structures, so that molecules are not filtered out of the process that wouldmoney have been successful as medicines, and molecules that cannot become useful medicines are eliminated from wasteful further development activities. Because of ADMET Predictor’s accuracy, we believe we have a significant strategic advantage in this developing area of technology.


expended.

MedChem Studio™ (formerly ClassPharmer™)

We have renamed our former ClassPharmer product to

Over the past several years, MedChem Studio to reflect the greatly enhanced capabilities it now has over the original ClassPharmer product. MedChem Studio has becomeupdates have resulted in a powerfulbetter tool for medicinal and computational chemists for both data mining and for designing new drug-like molecules.

MedChem Designer can be used to refine a small number of molecules; however, refining a very large number of molecules down to a few promising lead candidates is the primary function of MedChem Studio (with ADMET Predictor). MedChem Studio has features that enable it to generate very large numbers of new molecular structures using a variety ofde novodesign methods. Coupled with the accurate property predictions in ADMET Predictor, we believe the two programs provide an unmatched capability for chemists to search through hugelarge libraries of compounds that have undergone high-throughput screening experiments to find the most promising classes and molecules that are active against a particular target. In addition, MedChem Studio with ADMET Predictor can take an interesting (but not acceptable) molecule and very quickly generate many thousands of high quality analogs (i.e., similar new molecules) using several different algorithms. The result isa variety of design algorithms to generate new molecules that a reare predicted to be both active against the target as well as acceptable in a variety of ADMET properties.


MedChem Studio’s molecule design capabilities provideDesigner (see above) is also a numberpart of ways for chemistsMedChem Studio, so the user can click on the MedChem Designer icon and bring up the drawing window to rapidly generate large numbersinvestigate how further modifications to the structures of novel chemical structuresmolecules generated by MedChem Studio can improve their properties.

MedChem Studio version 3.0 was released in May 2012.

NCE Project

In March 2011, we initiated our own program of designing and making new molecules (NCEs, or New Chemical Entities) using the ADMET Design Suite (MedChem Studio/MedChem Designer/ADMET Predictor) based on intelligenceour belief in the suite’s capabilities. We selected as a target the malaria parasite Plasmodiumfalciparum, both because there is an unmet need for a very low-cost cure, and because we believed that external funding opportunities might exist if we were successful in generating high-quality lead compounds using our software. We completed the design process early in the first quarter of fiscal year 2012 and in September 2012 we announced that we had requested quotations from compounds that have already beenchemicalsynthesis companies for the cost and time to make a small set of molecules. Five molecules of our own design were synthesized and tested or from basic chemical reactions selectedfor inhibition of the parasite at the University of California at Riverside. We were hoping that at least one would show inhibition of the growth cycle of the parasite.

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Every molecule showed activity against the parasite at less than micromolar concentrations, with two showing activity at less than 100 nanomolar concentration (high potency) against the drug-sensitive strain of the parasite. They were then tested against the drug-resistant strain of the malaria parasite, and again potency was observed, with two molecules showing nanomolar activity. Several of these molecules were sent to another outside laboratory for additional experiments to measure a few key properties to compare the values versus our ADMET Predictor predictions. Our predictions for solubility, ionization constants (pKa), and lipophilicity were all well within accepted tolerances. Metabolism by human liver microsomes was much faster than predicted, probably due to metabolism by pathways our models do not yet predict. These molecules were only expected to be good lead molecules, not to be final drug molecules, so further structural changes would be expected to meet all requirements for an approved drug.

Our goal for this project was not actually to cure malaria. Rather, our goal was to demonstrate that a method of using our software tools to quickly and efficiently analyze high-throughput data, to generate new molecular structures, and to assess their qualities via ADMET Predictor, could result in high-quality lead candidates in a fraction of the user. Exporttime and cost usually required to reach that stage of drug development. We accomplished that and we have been presenting our results is available in Microsoft Excel™ format as well as other convenient file formats requested by users.


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scientific meetings and in webinars to a worldwide audience. We expect to pursue at least one more therapeutic target in the coming months.

DDDPlus

DDDPlus simulatesin vitro laboratory experiments thatused to measure the rate of dissolution of the drug and sometimes the additives (excipients) contained in tablets and capsules inunder a variety of experimental conditions. This one-of-a-kind software program is used by formulation scientists in industry and the U.S. Food and Drug Administration (FDA) to (1) understand the physical mechanisms affecting the dissolution rate for various formulations, (2) reduce the number of cut-and-try attempts to design new drug formulations, as well asand (3) to designin vitro dissolution experiments to better mimicin vivoconditions.

During 2010,fiscal year 2011, improvements were added to further enhance the value of this product, including numerous user convenience features, as well as more sophisticated handling of dosage forms that incorporate multiple polymers for controlled releasecontrolled-release formulations.


The FDA and a growing number of companies use DDDPlus in their work.

Development efforts onfor DDDPlus continued to be minimal during the fourth quarterfiscal year 2012 were limited because of the heavy loadpriorities on other programs.

GastroPlus

Our flagship product and largest source of testing and documentation of the Version 7.0 release of GastroPlus (see below) as well as contract consulting studies that required staff time to complete on schedule. A few small improvements and minor bug fixes were implemented.


GastroPlus
revenues is GastroPlus. GastroPlus simulates the absorption, pharmacokinetics, and pharmacodynamics of drugs administered to humans and animals, and is currently in use at numerous pharmaceutical companies, the FDA, the U.S. Food and Drug Administration (FDA)National Institutes of Health (NIH), and other government agencies in the U.S. and other countries. DuringBecause of GastroPlus, we were invited to joint the fourth quarterEuropean Innovative Medicines Initiative (IMI) program for Oral Bioavailibility Tools (“OrBiTo”). We were the only non-European company invited to participate. OrBiTo is a collaboration among 27 industry, academic, and government organizations working in the area of oral absorption of pharmaceutical products. Because we finalized Version 7.0, which includes three major market-expanding capabilities that have beenare outside of Europe, our participation in developmentthis project is at our own expense, while other members are compensated for overtheir work; however, we are a year. This release incorporates a highly sophisticated drug-drug interaction simulation capability funded by Hoffmann La Roche,full member with access to all of the ocular drug delivery model from our funded collaboration with Pfizer,data and the pulmonary drug delivery model we developed under our funded collaboration with GlaxoSmithKline.discussions of any other members. We believe this combination of capabilities puts GastroPlus further in front of t he limited competition we seeparticipation in this market niche.

At an international conference in Shanghai, China, in May 2008, Pfizer scientists presented a scientific poster describing a two-year study in which all four commercially available PBPK (physiologically based pharmacokinetics) simulation programs were compared for their abilityinitiative will enable us to predictbenefit from and to contribute to advancing the prediction of human pharmacokineticsoral absorption from preclinical (animal and data.

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We released version 8.0 of GastroPlus in vitro) data. The study was divided into two arms: intravenous and oral dosing.April 2012. This new version added many new features, including:

(1)extending the predictive capabilities for ocular and nasal/pulmonary dosing;
(2)adding a paracellular permeability capability that distinguishes between how some drug molecules permeate the intestinal membrane by moving through gaps between the epithelial cells from the diffusion through the cells;
(3)enhancing the PDPlus™ pharmacodynamic module to incorporate a tumor compartment model and to better deal with multiple metabolites; and
(4)providing enhanced graphical outputs and reporting capabilities requested by customers.

We are expecting to release version 8.5 of GastroPlus was ranked first in both arms. No other software was ranked consistently second or third.


The insight gained through GastroPlus simulations can guide project decisions in various ways. Amongbefore the kindsend of knowledge gained through such simulations are: (1) the best estimate for “first dose in human” for acalendar year 2012. This interim release adds several new drug prior to Phase I trials, (2) whether a potential new drug compound is likely to be absorbed at high enough levels to achieve the desired blood concentrations needed for effective therapy, (3) whether the absorption process is affectedcapabilities requested by certain enzymes and transporter proteins in the intestinal tract that may cause the amount of drug reaching the blood to be very different after absorption from one region of the intestine to another, (4) when certain properties of a new compound are probably adequately estimated by in silico predictions (such as ADMET Predictor) or from simple experiments, rather than through more expensive and time-consuming in vitro or animal experiments, (5) what the likely variations in blood and tissue concentration levels of a new drug would be in a large population, in different age groups or in different ethnic groups, and (6) whether a new formulation for an existing approved drug is likely to demonstrate “bioequivalence” (equivalent blood concentration versus time) to the currently marketed dosage form in a human trial (important for generic drug companies and the Office of Generic Drugs at the FDA, which has numerous licenses for GastroPlus).

Our marketing intelligence and reorder history indicate that GastroPlus continues to dominate its market niche in the number of users worldwide. In addition to virtually every major pharmaceutical company, licenses include government agencies in the U.S and abroad, a growing number of smaller pharmaceutical and biotech companies, generic drug companies, and drug delivery companies (companies that design the tablet or capsule for a drug compound that was developed by another company). Although these companies are smaller than the pharmaceutical giants, we believe they can also save considerable time and money through simulation. We believe this part of the industry, which we believe includes a few thousand companies, represents major growth potential for GastroPlus. Our experience has been that the number of new compa nies adopting GastroPlus continues to grow steadily, adding to the base of annual license renewals each year. Recent consolidations by larger companies have not affected our sales to date. In fact, because of the increased need for improving productivity, those companies have typically adopted in silico tools at ever-greater levels, with the result that large company licenses have typically increased at renewal time even in the face of such consolidation.


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customers.

Contract Research and Consulting Services

Our recognized world-class expertise in oral absorption and pharmacokinetics is evidenced by the fact that our staff members have been speakers or presenters at over 5080 prestigious scientific meetings worldwide in the past fivefour years. We frequently conduct contracted studies for large customers (including top 5 pharmaceutical companies) who have particularly difficult problems and who recognize our expertise in solving them, as well as for smaller customers who prefer to have studies run by our scientists rather than to license our software and train someone to use it. The demand for our consulting services has been increasing steadily, and we expect this trend to continue.steady. Long-term collaborations and shorter-term consulting contracts serve both to showcase our technologies and to build and strengthen customer relat ionships.


Government-Funded Research
relationships.

During fiscal year 2012 we continued to work on our 5-year collaboration agreement with the Center for Food Safety and Applied Nutrition (CFSAN) of the FDA using ADMET Predictor/Modeler to build predictive models for likely toxicities of food additives and contaminants. During this first year of the collaboration, we analyzed FDA databases and worked with FDA scientists to ensure that the FDA data to be used for building new predictive models is as accurate as we can reasonably make it. Both FDA scientists and our scientists are building a series of models to classify new compounds as toxic or nontoxic from FDA datasets. Included in this effort was a special modification to ADMET Predictor to allow the user to set a minimum value for specificity or sensitivity when building a model. Sensitivity refers to how well a model identifies toxic (or any other property) compounds. A model that determined all compounds are toxic would have 100% sensitivity, because all toxic compounds would be labeled as such; however, all nontoxic compounds would also be labeled toxic. Specificity refers to how well a model distinguishes between toxic and nontoxic compounds. Increasing one usually results in decreasing the other. Depending on the purpose of the model, some scientists will prefer to train models that emphasize one statistic over the other.

Product Development

Development of our software is focused on expanding product lines, designing enhancements to our core technology and integrating existing and new products into our principal software architecture and platform technology. We are well along inintend to offer regular updates to our $525,000 Phase II Small Business Innovation Research (“SBIR”) grant awarded by the National Institutes of Health (“NIH”). This SBIR grant has provided funds that allowed usproducts and to continue to look for opportunities to expand staff and grow theour existing product line without adversely affecting earnings, because the expenses associated with the efforts in the grant study are funded largely through the grant with some company support.
suite.

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PHARMACEUTICAL SOFTWARE PRODUCT DEVELOPMENT
Although

We develop all of our development work cannot be disclosed for competitive reasons, someproducts internally. We have also licensed products or have otherwise acquired products, or portions of our development efforts during this reporting period included:


(1) ADMET Predictor/ADMET Modeler Upgrades
Duringproducts, from other organizations. These arrangements sometimes require the fourth quarter,payment of royalties by us. We intend to continue to license or otherwise acquire technology or products from third parties. We currently have two royalty agreements, one with TSRL, Inc. (“TSRL”) and another with Symyx Technologies (“Symyx”). In July 1997, we released version 5.0 of ADMET Predictor, completingentered into a nearly year-long effort that resulted in major improvementsroyalty agreement with TSRL pursuant to which royalties were paid to TSRL from revenues on each license for GastroPlus basic software. In March 2010, we entered into a royalty agreement with Symyx, which was merged with Accelrys, Inc., pursuant to which royalties were paid to Symyx from revenues on each license for Metabolite module. After we made a buyout agreement with Enslein Research, we combined Metabolism module and Metabolite module, and currently we pay royalties to Symyx from the program. This new version has taken advantage of the progress we have made on our SBIR grant with the NIH, which has enhanced the rapid atomic partial charge calculations and the resultant improved descriptor set from which all models are built. Version 5.0 has all new retrained existing models, plus a number of new property models, as well as a variety of user interface improvements that we believe set this best-in-class software even further ahead of the competition. We are continuing to work under our SBIR grant on the ability to predict which atoms in a molecule are most likely to be affected by metabolism by certain enzymes (metabolic site prediction). T his is a new capability, and we expect it will be launched in early 2011.

(2) MedChem Studio
We launched MedChem Studio 1.0 during the fourth quarter, and have been presenting it in a variety of forums since then. Our CEO gave two half-day seminars in Japan in October demonstrating the capabilities of the MedChem Studio/ADMET Predictor combination. MedChem Studio is now both faster and more compact than the previous version of ClassPharmer, and it incorporates a significant number of new data mining options for visualizing various types of information generated by the program. We believe this is a product with potential for wide acceptance as a data mining and de novo molecule design tool. Further improvements are in development and we will be announcing some additional unique and powerful capabilities in the near future.

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(3) DDDPlus
We have continued to improve DDDPlus by adding capabilities and features requested by our customers and potential customers, as well as capabilities and features identified in-house.

(4) GastroPlus
Recent improvements to GastroPlus have been many and complex. Most of these developments were funded through our collaborations with three of the top five pharmaceutical companies in the world.  We have added ocular delivery of drugs under one collaboration, nasal/pulmonary delivery under another, and drug-drug interaction analysis under a third. Our recent poster presentations at scientific meetings that have presented analyses done with GastroPlus have drawn considerable interest with respect to these new capabilities.

(5) MembranePlus™
MembranePlus is a computer program that simulates in vitro experiments that measure the permeability of new drug-like molecules through a layer of living cells or through an artificial membrane. These experiments are conducted in order to estimate the permeability of new drug compounds through the cells lining the intestinal walls and other tissues of humans and various animals. However, such experiments often do not produce results that are easily translated into in vivo permeabilities. We believe that a detailed mechanistic simulation of such in vitro experiments can provide the insight and understanding needed to provide reasonably accurate estim ates of permeability in different regions of human and animal tissues from in vitro data.

This development effort accelerated during fiscal year 2005 with the hiringsale of a new Ph.D. scientist who focused on this program.  The simulation is currently predicting the movement of drug molecules from the bulk fluid, into the membranes at the surface of a cell layer, through the surface membrane, through the interior of the cell, into the opposite surface membrane,Metabolism module.

Marketing and through it to the bulk fluid on the opposite side of the cell layer.  Although a few technical issues remain to be resolved, we are optimistic that the simulation can become a unique tool for the analysis of data from these experiments, and can enable researchers to more accurately estimate human intestinal permeability from these in vitro experiments.


This project was put on hold in September 2005 because the scientist responsible for MembranePlus, Dr. Viera Lukacova, was assigned to take over GastroPlus when the previous product manager left the company. We are interviewing candidates to expand the Simulation Technologies Team, one of whom may work on MembranePlus under Dr. Lukacova’s direction.

MARKETING AND DISTRIBUTION
Distribution

We market our pharmaceutical software and consulting services through attendance and presentations at scientific meetings, exhibits at trade shows, seminars at pharmaceutical companies and government agencies, through our web pages on the Internet, and using various communication media to our compiled database of prospectprospects and customer names. In recent monthsAt the American Association of Pharmaceutical Scientists (AAPS) conference in Chicago in October 2012, there were numerous different presentations and posters presented in which the research that was reported was done using our software. Many of those were from industry and FDA scientists, seven were from our staff.

During fiscal year 2012 we added anone full-time salesperson. We have one independent sales representativedistributor in Europe,Japan and we have two independent representatives in China; however, our scientific team is also the majority of our sales and marketing team, assisting our DirectorVice President of Marketing and Sales and his staff with trade shows, seminars, and customer training both via Internet and on-site. We believe that this is more effective than a completely separate sales team for several reasons: (1) customers appreciate talking directly with de velopersdevelopers who can answer a wide range of technical questions about methods and features in depth; (2) our scientists benefit from direct customer contact by gaining an appreciation for the environment and problems of the customer,customer; and (3) the relationships we build through scientist-to-scientist contact are stronger than through salesperson-to-scientist contacts.


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We use the Internet to provide product information and software updates, and as a forum for user feedback and information exchange. We have cultivated market share in North America, South America, Europe, and inJapan, Australia, New Zealand, Singapore, and Japan, andthe People’s Republic of China. Internet and e-mail technologies have had a strong positive influence on our ability to communicate with existing and potential customers worldwide.


PRODUCTION

Production

Our pharmaceutical software products are designed and developed entirely by our development team in California, with locations in Lancaster, Petaluma, San Jose, and San Diego, California.Diego. The principal materials and components used in the manufacture of simulation software products include CD-ROMs and instruction manuals, which are also produced in-house and through outside contractors. In-house graphic art and engineering talent enables us to accomplish this production in a cost-efficient manner.


COMPETITION

Competition

In our pharmaceutical software and services business, we compete against a number of established companies that provide screening, testing and research services, and products that are not based on simulation software. There are also software companies whose products do not compete directly, but are sometimes closely related.related, to ours. Our competitors in this field include some companies with financial, personnel, research and marketing resources that are greater than ours. Management believes there is currently no significant competitive threat to GastroPlus or DDDPlus.DDDPlus, however, one could be developed over time. MedChem Studio, MedChem Designer, and ADMET Predictor/ADMET Modeler operate in a more competitive environment; however, independent product comparisons have been very favorable toward our offerings, with ADMET Predictor consistently ranked first in predictiv e accuracy.environment. Several other companies presently offer simulation or modeling software, or simulation-software-based services, to the pharmaceutical industry.

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Major pharmaceutical companies conduct drug discovery and development efforts through their internal development staffs and through outsourcing some of this work. Smaller companies generally need to outsource a greater percentage of this research. Thus, we compete not only with other software suppliers, but also with the in-house development teams at some of the larger pharmaceutical companies.


We are not aware of any significant threat from competition in the area of gastrointestinal absorption simulation.

Although competitive products exist, both new licenses and license renewals for GastroPlus have continued to grow in spite of this competition. We believe that we enjoy a dominant market share in this segment.


We believe that the success of our recent NCE project in which we designed, had synthesized, and tested a number of new molecules to treat malaria has cultivated strong interest in our ADMET Design Suite (ADMET Predictor/ MedChem Studio/ MedChem Designer). Presentations in the U.S., Japan, and Europe over the past several months since the results were released have been well received and companies have requested evaluation copies of the software to determine whether it can increase their productivity.

We believe the key factors in competing in this field are our ability to develop industry-leading simulation and modeling software and related products and services to effectively predict activities and ADMET-related behaviors of new drug-like compounds, to design new molecules with acceptable activity and ADMET properties, to develop and maintain a proprietary database of results of physical experiments that will serve as a basis for simulated studies and empirical models, to attract and retain a highly skilled scientific and engineering team, and to develop and maintain relationships with research and development departments of pharmaceutical companies, universities and government agencies.


We are actively seeking acquisitions to expand the pharmaceutical software and services business. Earlier attempts to acquire other companies have not been successful either in arriving at mutually agreeable terms and conditions, or because of adverse conditions discovered during our comprehensive due diligence process.




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WORDS+

PRODUCTS
Our wholly owned subsidiary, Words+, has been focused on introducing and improving augmentative and alternative communication and computer access software and devices for people with disabilities for over 29 years. The introduction of EyeProTM, an eyegaze product, in 2010 has increased our revenue and marketshare. Eyegaze technology allows people to operate a computer or communication device by simply looking at the screen, and has been a major breakthrough for people with severe disabilities.

MARKETING AND DISTRIBUTION
We market augmentative and alternative communication products through a network of employee representatives and independent dealers and resellers. Webinars and remote interaction using web-based evaluation, setup and training, introduced last year, have become standard parts of our operation.  During the last two quarters, we have seen an increase in the number of family members, caregivers, teachers, and aides attending the live and recorded webinars. This is a significant change in the speech pathologist-to-patient relationship, and allows the speech pathologists' professional experience and advice to extend beyond the therapy session to achieve more effective results for their clients. It has also allowed our sales force to spend less time training and more time selling.

We currently have 39 sales representatives worldwide: 1 salaried sales manager and 2 salaried sales employees in California, 11 independent distributors and 6 independent resellers in the U.S., and 19 sales representatives overseas – 4 in Australia, and 1 each in New Zealand, Canada, England, Norway, Finland, The Netherlands, France, Ireland, Italy, Israel, Japan, Korea, Mexico, Malaysia, and Taiwan.  We also have 2 inside support persons, who answer e-mails and telephone inquiries on our toll-free telephone line and who provide technical support. Additional outside sales persons and independent dealers and resellers are being actively recruited.

We direct our marketing efforts to speech pathologists, occupational therapists, rehabilitation engineers, special education teachers, disabled persons and relatives of disabled persons. We maintain a mailing list of over 10,000 people made up of these professionals, consumers and relatives, and we mail various marketing materials to this list.  These materials include our catalog of products and announcements regarding new and enhanced products.

We participate in industry conferences held worldwide that are attended by speech pathologists, occupational and physical therapists, special education teachers, parents and consumers.  We and others in the industry demonstrate our products at these conferences and present technical papers that describe the application of our technologies and research studies on the effectiveness of our products.  Words+ attended three major national conferences in October and November 2010. We responded to calls for papers and presented five different professional sessions during these conferences, representing an all time high with more than twice our normal presentation activity. We also advertise in selected publications and websites of interest to persons in this market.

We estimate that for approximately 47% of our sales of augmentative and alternative communication (“AAC”) software and hardware, purchases are funded primarily by third parties such as Medicaid, Medicare and private insurance. School special education budgets, vocational rehabilitation, other governmental programs, private purchases and charitable assistance account for most of the other purchases. Medicare provides coverage for augmentative communication devices.

Our personnel provide advice and assistance to customers and prospective customers on obtaining third-party financial assistance for purchasing our products. Third-party funding grew slowly for the first 20 years of operation; however, the addition of Medicare coverage for AAC devices in 2001 resulted in significant increases in third-party funding in recent years. Our Medicare/Medicaid and other third-party-funded sales have grown, with the majority of total sales are now funded by a third party.  Medicare/Medicaid sales are subject to funding caps that limit the amounts paid for our products, and payment by some agencies can be slow, making this market segment somewhat more difficult than others. Collection of accounts receivable has been a significant problem from certain state Medicaid agencies, Medicai d, and private insurance. Our financial reporting includes allowances for bad debts that are based on assumptions that we will collect a historical percentage of accounts receivable that fall in different aging categories: less than 6 months, 6-12 months, 12-24 months, and over 24 months. Although we may not give up on any of the invoices that are included in the allowances for bad debts, we recognize that responsible financial reporting requires us to be conservative in these estimates.


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PRODUCTION
Disability software products are either loaded onto computer hard disk drives by our employees or copied to diskettes, CD-ROM, or memory cards, which is performed in-house.  Most software customers also buy their notebook personal computers from us, which we purchase at wholesale prices and resell at a markup.  We purchase microprocessors that are part of dedicated devices such as MessageMates™.  We design our cases, printed circuit boards, labels and other components of products such as SAM Communicator™ and our popular Conversa™ Sound Pack.  We outsource the extrusion, machining and manufacturing of certain components.  All final assembly and testing operations are done by our employees at our facility.

Our products are shipped from our Lancaster, California facility either directly to the customer or to the salesperson, dealer or reseller.  Historically for major products, the outside salesperson, dealer or reseller either delivers the product or visits the customer after delivery to provide training. In our new remote location interaction sales and delivery model, more deliveries are being completed utilizing internet with video support for setup, and webinars plus individual live video interaction for training.

COMPETITION
The AAC industry in which we operate is highly competitive and some of our competitors have greater financial and personnel resources than ours.  The industry is made up of about six major competitors including Words+, and a number of smaller ones. Following the introduction of EyePro and other products to complement our current catalog, we are now focused on developing new products in-house.

We believe that the competition in this industry is based primarily on the quality of products, quality of customer training and technical support, and quality and size of sales forces.  Price is a competitive factor but we believe price is not as important to the customer as obtaining the product most suited to the customer’s needs, along with strong after-sale support.  We believe that we are a leader in the industry in developing and producing some of the most technologically advanced products and in providing quality customer training and technical support.  We believe that the potential exists for significant increases in the sales of our disability products; however, there are few barriers to entry in the form of proprietary or patented technology or trade secrets in this ind ustry.  While we believe that cost of product development and the need for specialized knowledge and experience in this industry would present some barrier to entry for new competition, other companies may enter this industry, including companies with substantially greater financial resources than ours.  Furthermore, companies already in this industry may increase their market share through increased technology development and marketing efforts.

A recent development in the competitive environment is the appearance of communication devices based on the Apple iPod and iPad. This is a change in our industry, a change in service delivery and funding. We are working to determine how we fit in this environment. New Windows and Android phones will also have an impact.


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TRAINING AND TECHNICAL SUPPORT

Customer training and technical support are important factors in customer satisfaction for both our pharmaceutical and disability products, and we believe we are an industry leader in providing customer training and technical support in both of our business areas. For pharmaceutical software, weWe provide in-house seminars at customers’, and potential customers’, sites. These seminars often serve as initial training in the event the potential customer decides to license or evaluate our software. Technical support is provided after the sale of any software in the form of on-site training (at the customer’s expense), web meeting,meetings, telephone, fax, and e-mail assistance to the customer’s users during the customer'scustomer’s license period. We have used Internet meetings extensively to provide demonstrations and customer assistance, resulting in rapid response to requests worldwide and reducing our travel time and expenses.


For disability products, our salesperson, dealer or reseller historically provided initial training to the customer for major systems -- typically two to four hours.  This training is typically provided not only to the user of the product but also to speech pathologists, occupational therapists, rehabilitation engineers, teachers, parents and others who will assist the user.  This initial training for the purchase of full systems is often provided as a part of the price of the product.  Additional training and service calls are available for a fee. Live and recorded webinars introduced last year have significantly changed our service delivery model, making it more accessible to people who need training, and reducing the amount of time our sales force spends traveling and providing on-sit e, one-on-one training and support. Our salespeople still visit in person whenever appropriate, but the professional on-line training and support have greatly reduced this need. Feedback from surveys and increasing webinar attendance indicate improved customer satisfaction with our products and service delivery. The remote service delivery model is becoming an expectation in our industry and we have already implemented it.

Technical support for both pharmaceutical software and disability products is provided by our life sciences team and our inside sales and support staff based at our headquarters facilities in Lancaster, California. We provide free telephone support offering unlimited toll-free numbers in the U.S. and Canada, and e-mail and web-based support for all of our pharmaceutical software and disability products worldwide. Technical support for pharmaceutical software products is minimal, averaging a few person-hours per month. Technical support for Words+ products varies from none for most customers to as much as several hours for others.


RESEARCH AND DEVELOPMENT

We believe that our ability to grow and remain competitive in our markets is strongly dependent on significant investment into research and development (“R&D”). R&D activities include both enhancement of existing products and development of new products. Development of new products and adding functionality to existing products are capitalized in accordance with Financial Accounting Standards Board (“FASB”) Accounting Standards Codification (“ASC”) 985-20.985-20,“Costs of Software to Be Sold Leased, or Marketed”. R&D expenditures, which primarily relate to both capitalized and expensed salaries, R&D supplies, laboratory testing, and R&D consulting, were approximately $1,857,000$1,900,000 during fiscal year 2010,2012, of which $887,000$952,000 was capitalized. R&D expenditures during fiscal year 20092011 were approximately $1,975,000,$1,261,000, of which $674,000$797,000 was capitalized.

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Our pharmaceutical business R&D activities during fiscal year 20102012 were focused on improving our ADMET Predictor/ADMET Modeler, MedChem Studio, MedChem Designer and GastroPlus products.


Our R&D activities for our Words+ subsidiary were focused on development of our new EyePro™ eyegaze product line, improvement of a tablet-computer-based system called Conversa, and two new hardeare development projects that we are not ready to announce at this time.

EMPLOYEES

As of August 31, 2010,2012, we employed 3925 full-time employees and 1no part-time employees, including 1917 in research and development, 84 in marketing and sales, 74 in administration and accounting and 6 in production.accounting. Currently 1415 employees hold Ph.D.s and 1 is a Ph.D.’s candidate in their respective science or engineering disciplines and one is a Ph.D. candidate.  Addtionally, 3disciplines. Additionally, 4 employees hold one or more Master’s degrees. Most of the senior management team and the members of our Board of Directors hold graduate degrees. We believe that our future success will depend, in part, on our ability to continue to attract, hire and retain qualified personnel. TheWe continue to seek additions to our life sciences team although the competition for such personnel in the pharmaceutical industry and in the augmentative and alternative communication device and computer software industry is intense. None of our e mployeesemployees is represented by a labor union, and we have never experienced a work stoppage. We believe that our relations with our employees are good.



10


PATENTS

Intellectual Property and Other Proprietary Rights

We own two patents that were acquired as part of our 2005 acquisition of certain assets of Bioreason, Inc., and we have applied for a patent related to a product development that is under way by our Words+ subsidiary. in November 2005. We primarily protect our intellectual property through copyrights and trade secrecy. Our intellectual property consists primarily of source code for computer programs and data files for various applications of those programs in both the pharmaceutical software and the disability products businesses. In the disability products business, electronic device schematics, mechanical drawings, and design details are also intellectual property. The expertise of our technical staff is a considerable asset closely related to intellectual property, and attracting and retaining highly qualified scientists and engine ersengineers is essential to our business.


EFFECT OF GOVERNMENT REGULATIONS

Our pharmaceutical software products are tools used in research and development and are neither approved nor approvable by the FDA or other government agencies.


Most of our products for the disabled are funded by Medicare or Medicaid, schools, the Veteran’s Administration, and other insurance programs. Changes in government regulations regarding the allowability of augmentative communication aids and other assistive technology under such funding could affect our business.

ITEM

Item 1A – RISK FACTORS


risk factors

Not applicable because the Company iswe are a smaller reporting company.


ITEM

Item 1B – UNRESOLVED STAFF COMMENTS


Not applicable.


ITEM

Item 2 –PROPERTIES


–propertIES

We lease approximately 13,500 square feet of space in Lancaster, California. The original agreement had a five-year term with two (2), three-three (3) year-year options to extend. Since the original five-year term will expireexpired in February 2011, we have exercised the first of the two three-year(2), three (3)-year options. The base rent started at the rate of $18,445 per month plus common area maintenance fees. The base rental rate increases at 4% annually and currently it is $21,578currently $23,339 per month, plus common area maintenance fees. We believe that this facility is sufficient for our current needs and growth for the nearforeseeable future.

After the sale of our subsidiary, Words+, we entered into a sublease agreement under which Words+ pays 20%of the monthly rent we pay to our landlord, plus 20% of facility-related operating expenses. This sublease is on a month-to-month basis commencing on January 1, 2012. We report all of our lease expense under Selling, General and Administrative expense; however, the payments received from Words+ are reported under Other Income. Also see Item 7 “Management’s Discussion and Analysis of Financial Condition and Results of Operations” and Note 4 under the Notes to the Financial Statements included in this Annual Report on Form 10-K for more information.

8
ITEM

Item 3 – LEGAL PROCEEDINGS


The Company is

We are not a party to any legal proceedings and isare not aware of any pending legal proceedings of any kind.




11


ITEM

Item 4 – [RESERVED]




MINE SAFETY DISCLOSURES.

Not applicable.

PART II


ITEM

Item 5 – MARKET FOR REGISTRANT’S COMMON EQUITY AND RELATED STOCKHOLDER MATTERSfor Registrant’s Common Equity and Related Stockholder Matters AND ISSUER PURCHASES OF EQUITY SECURITIES


Our Common Stock

There is currently traded on the NASDAQ Stock Market (NASDAQ) under the symbol “SLP”.  According to the records of our transfer agent, we had approximately 57 shareholders of record and approximately 1,550 beneficial owners as of August 31, 2010.  The following table sets forth the low and high sale prices for our Common Stock as listed on the NASDAQ for the last two fiscal years.  The board of directors declared a 2-for-1 stock split in August 2006 and another 2-for-1 split in October 2007, and our common stock has been trading at post-split prices since October 2, 2007.  The prices in the table below reflect post-split prices.  We have not paid cash dividends on our Common Stock.  We currently intend to retain our earnings for future growth, and therefore do not anticipate paying cash dividends in the foreseeable future.  Any further determination as to the payment of dividends will be at the discretion of our Board of Directors and will depend among other things, on our financial condition, results of operations, capital requirements and such other factors as the Board of Directors deems relevant.


On October 23, 2008, our board of directors authorized ano share repurchase program enabling the buyback of up to $2.5 million in shares during a 12-month period beginning Monday, October 27, 2008.  The actual repurchase started on December 2, 2008; therefore the board of directors extended it through December 1, 2009 in order to have a full 12-month period.  The Company opened an account with Morgan Stanley Smith Barney for the purchase of such securities. Funds for any stock purchases are drawn from the Company’s cash reserves. The Company repurchased 1,026,483 shares at an average price of $1.3823 per share prior to December 1, 2009.
On January 10, 2010, the board of directors authorized a second share repurchase program (Phase II) effective as of February 15, 2010.  The renewed program enablespending, and the Company to buy back up to one million shares during a 12-month period.  Undermade no repurchases of its securities within the Phase II program,fourth quarter of the Company has purchased 718,089 shares at an average price of $2.6952 per share as of November 19, 2010.

fiscal year 2012.

The following table shows low and high sales price for the Company’s common stock for the last eight fiscal quarters.


  Low Sales Price  High Sales Price 
FY10:      
Quarter ended August 31, 2010  2.04   2.52 
Quarter ended May 31, 2010  1.67   2.50 
Quarter ended February 28, 2010  1.35   1.72 
Quarter ended November 30, 2009   1.32   1.79 
         
FY09:        
Quarter ended August 31, 2009  1.20   1.86 
Quarter ended May 31, 2009  0.90   1.25 
Quarter ended February 28, 2009  0.87   1.12 
Quarter ended November 30, 2008    1.01   1.90 


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EQUITY COMPENSATION PLAN INFORMATION

  Low Sales Price  High Sales Price 
FY11:        
Quarter ended August 31, 2012  3.76   4.46 
Quarter ended May 31, 2012  3.66   4.61 
Quarter ended February 29, 2012  2.91   4.25 
Quarter ended November 30, 2011  2.97   3.24 
         
FY10:        
Quarter ended August 31, 2011  2.76   3.47 
Quarter ended May 31, 2011  2.68   3.27 
Quarter ended February 28, 2011  2.42   3.69 
Quarter ended November 30, 2010  2.40   3.50 

COMPANY STOCK PRICE PERFORMANCE

The following table provides a summary of Equity Compensation Plan Information.



Equity Compensation Plan Information (1)
Plan category
Number of securities to
 be issued upon exercise
 of outstanding options,
warrants and rights
Weighted-average
 exercise price of
outstanding options,
warrants and rights
Number of securities
remaining available for
future issuance under
equity compensation plans
 (excluding securities
 reflected in column (a))
 (a)(b)(c)
Equity compensation plans approved by security holders1,493,902$   1.13346,834
Equity compensation plans not approved by security holders000
Total1,493,902 346,834

stock price performance graph below and stock price tables above are not required by the SEC and shall not be deemed to be incorporated by reference by any general statement incorporating by reference this Annual Report on Form 10-K into any filing under the Securities Act or under the Exchange Act except to the extent that the Company specifically incorporates this information by reference, and shall not otherwise be deemed soliciting material or filed under such the Securities Act or the Exchange Act.

(1)The Company is authorized to issue stock options under the following compensation arrangement:9
 a.4,000 shares per year per person to Directors as a part of their annual stipends.
b.50 shares for each $1,000 of net income before taxes at the end of each fiscal year (up to a maximum of 120,000 options) to CEO over the term of the current employment agreement
STOCK REPURCHASE

The detailsgraph below compares the cumulative total shareholder return on the common stock of repurchases made during the forth fiscal quarter endedCompany from the last day of the first month of trading of the Company’s common stock from August 31, 2010 are listed2002 to August 31, 2012 with the cumulative total return on the Russell 2000 Index, and the S&P 600 Small Cap Index (assuming the investment of $100 in the Company’s common stock and in each of the indices on August 31, 2002, and reinvestment of all dividends). The stock price performance on the graph is not necessarily indicative of future stock price performance.

 

The graph above was plotted using the following table.


Period
Total Number of
Shares Purchased
Average Price
Paid per Share
Total Number of
Shares Purchased
 as Part of Publicly
Announced Program
Remaining Shares
Authorized for
Repurchase Under the
Share Repurchase
Plan – Phase II
06/01/10 to 06/30/1033,665$2.367033,665709,258
07/01/10 to 07/31/1018,789$2.443318,789690,469
08/01/10 to 08/31/1010,878$2.428310,878679,591
 
Total
63,332$2.400163,332 


data:

  Russell 2000  S&P 600   SLP 
30-Aug-02 $390.96   100.00  $30.35   100.00  $0.38   100.00 
29-Aug-03 $497.42   127.23  $37.29   122.87  $0.61   160.53 
31-Aug-04 $547.93   140.15  $42.80   141.02  $0.80   210.53 
31-Aug-05 $666.51   170.48  $54.07   178.15  $0.82   215.79 
31-Aug-06 $720.53   184.30  $57.63   189.88  $1.06   278.95 
31-Aug-07 $792.86   202.80  $65.33   215.26  $6.44   1,694.74 
29-Aug-08 $739.50   189.15  $61.01   201.02  $1.75   460.53 
31-Aug-09 $572.07   146.32  $48.21   158.85  $1.74   457.89 
31-Aug-10 $602.06   154.00  $51.82   170.74  $2.37   623.68 
31-Aug-11 $726.81   185.90  $64.43   212.29  $3.12   821.05 
31-Aug-12 $812.09   207.72  $75.33   248.20  $4.46   1,173.68 

* Close price adjusted for dividends and splits.

ITEM

Item 6 – SELECTED FINANCIAL DATA


Not applicable because the Company iswe are a smaller reporting company.


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13




ITEM

Item 7 – MANAGEMENT’S DISCUSSION AND ANALYSIS OFManagement’s Discussion and Analysis oF FINANCIAL CONDITION AND RESULTS OF OPERATIONS


of OperationS

The following discussion and analysis should be read in conjunction with the Consolidated Financial Statements and related notes included in this Annual Report on Form 10-K.

Management Overview

Fiscal year 20102012 highlights:

·We signed two funded collaboration agreements with top-5 pharmaceuticalcompanies to extend the capabilities of our flagship GastroPlus™ software with an enhanced oral cavity absorption model and to add the ability to simulate dosing through the skin.
·We successfully completed the first year of our five-year renewable collaboration with the Center for Food Safety and Nutrition of the FDA to develop predictive toxicity models for food additives and contaminants
·On November 30, 2011, we completed the sale of Words+, Inc. for $1,973,000 in cash. Words+ operations are now presented as discontinued operations in this Form 10K
·We completed a drug design process targeting the malaria parasite, including data mining of a large public domain database, design of new molecular structures, synthesizing a selected set of molecules, and testing them against the parasite. Every molecule we designed and synthesized inhibited the growth of the parasite.
·We attempted to acquire certain assets of Entelos through their bankruptcy proceeding. We were unsuccessful in that offering.
·We expanded our technical staff, adding three new Ph.D. scientists to the Life Sciences department and one new scientist to our marketing and sales department.
·We reinitiated the development of the MembranePlus™ software program for simulation of in vitro permeability experiments. This project had begin in 2004 but was postponed for more pressing activities. With our expanded scientific staff, we have now been able to continue the development of this new product. We expect to release it during calendar year 2013.
·The Board of Directors declared an ongoing quarterly cash dividend of $0.05 per share ($0.20 per year). We made dividend distributions in March, May, and August and the board declared the next distribution for November 13, 2012, which is in fiscal year 2013. The total cash distribution each quarter is just below $800,000, so we paid out approximately $2.4 million in dividends in fiscal year 2012.
·Our cash position remained strong, with cash at the end of the fiscal year of $12.7 million, compared to $10.2 million at the end of fiscal year 2011.

Fiscal year 2012 Financial Summary:

·Gross revenues increased 8.1% to $9,449,000 from $8,739,000 in fiscal year 2011
·Selling, General and Administrative expenses increased 6.1% to $3,379,000 from $3,186,000 in fiscal year 2011
·Research and Development expenditures increased 50.7% to $1,900,000 from $1,261,000 in fiscal year 2011. Approximately $140,000 of this increase was for outside services to synthesize and test the new molecules we designed to inhibit the growth of the malaria parasite.
·Income from continuing operations increased 5.6% to $2,812,000 from $2,663,000 in fiscal year 2011

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Strategy Going Forward:

·Continue to advance our software offerings through both our in-house developments and our funded and unfunded collaborations with our industry and government customers
·Continue to seek acquisition and partnership possibilities to broaden our offerings of products and services
·Continue our aggressive marketing and sales campaign including attending and exhibiting at numerous scientific conferences and meetings, expanded use of social media, and expanded advertising
·Increase our marketing and sales efforts with respect our consulting services in both pharmacokinetics and in small molecule design
·Seek partners for our malaria new chemical initiative to take it further into development
·Select a new target and repeat our drug design, synthesis, and test activities as we did for malaria to further demonstrate the capabilities of our ADMET Design Suite to generate high-quality lead compounds in a fraction of the time and cost normally required

Fiscal year 2012 was a record year comprised of four record quarters. We believe the continued growth of our pharmaceutical software and services business segment is the result of increasing adoption of simulation and modeling software tools such as those we produce, as well as the expertise we offer as consultants to assist companies involved in the research and development of new medicines, which has resulted in a continuing series of study contracts with pharmaceutical companies ranging from several of the largest in the world to a number of medium-sized and smaller companies in the U.S. and Europe.

During FY10fiscal year 2012 we released major upgrades to three of our fourfive pharmaceutical software offerings, we made substantial progress onas well as to our SBIR grant from the NIH, and we further expanded our Life Sciences staff.software product called MedChem Designer. Our financial performance enabled us to continue to increase our cash deposits, remain debt-free, and continue to invest in the aggressive marketing and sales activities we began in early 2009 in order to reach a wider customer base.

We have not been successful in identifying and completing any acquisitions during this reporting period in spite of a number of investigations and due diligence activities. In eachevery case, either our due diligence activities revealed undesirable aspects of the potential acquisition, or terms and conditions agreeable to both sides were not able to be reached. It is our intent to continue to search for acquisition opportunities that would be compatible with our current businesses and that would be immediately accretive, i.e., adding to both revenues and earnings.

We

In the past, we have used some of our cash to repurchase shares of our common stock because we believe that reducing the number of fully diluted shares provides greater value to our shareholders than receiving a low interest rate on our cash deposits, and because we believe that our cash deposits after such repurchases remain sufficient to accomplish any reasonable potential acquisitions as well as to maintain sufficient cash reserves to ensure meeting operational needs for the foreseeable future.

Our Words+ subsidiary has begun to turn around. Although there are no stock repurchase programs pending, the results for the entire FY10 were slightly negative, the fourth fiscal quarter resulted in a profitboard of over $130,000, driven partlydirectors may consider additional repurchases at any time at prices and under conditions set by the introduction of our new EyePro eyegaze system in May 2010. We expect this trend to continue going forward; however, there can be no assurances that it will.

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board.

Results of Operations

The following sets forth selected items from our statements of operations (in thousands) and the percentages that such items bear to net sales for the fiscal years ended August 31, 20102012 (“FY10”FY12”) and August 31, 20092011 (“FY09”FY11”).

  FY10  FY09 
Net sales $10,712   100.0% $9,143   100.0%
Cost of sales  2,546   23.8   2,321   25.4 
Gross profit  8,166   76.2   6,822   74.6 
Selling, general, and administrative  4,325   40.4   3,896   42.6 
Research and development  970   9.1   1,114   12.2 
Total operating expenses  5,295   49.5   5,010   54.8 
Income from operations  2,871   26.7   1,812   19.9 
Interest income  101   0.9   94   1.0 
Interest expense  (1)  (0.0)  -   - 
Miscellaneous Income  1   0.0   1   0.0 
Gain on sale of assets  2   0.0   -   - 
Gain on currency exchange  130   1.2   120   1.3 
Total other income  233   2.1   215   2.4 
Net income before taxes  3,104   28.8   2,027   22.2 
Provision for income taxes  (948)  (8.8)  (615)  (6.7)
Net income  2,156   20.0%  1,412   15.4%
FY10 COMPARED WITH FY09

   Fiscal years ended 
   8/31/12   8/31/11 
Net sales $9,449   100%  $8,739   100% 
Cost of sales  1,510   16.0   1,559*  17.8 
Gross profit  7,939   84.0   7,180   82.2 
Selling, general and administrative  3,379   35.8   3,186*  36.5 
Research and development  948   10.0   464*  5.3 
Total operating expenses  4,327   45.8   3,650   41.8 
Income from operations  3,612   38.2   3,530   40.4 
Other income  343   3.6   168   1.9 
Net income before taxes  3,955   41.9   3,698   42.3 
(Provision) for income taxes  (1,143)  (12.1)  (1,035)  (11.8)
Income from continuing operations  2,812   29.8%   2,663   30.5 
Results of discontinued operations, net of tax  216   2.3   52   0.6 
Net income $3,028   32.1%  $2,715   31.1% 

* Numbers in the prior year have been reclassified to conform to the current year’s presentation.

FY12 Compared with FY11

Net Sales

Consolidated net

Net sales increased $1,569,000,$710,000, or 17.2%8.1%, to $10,712,000$9,449,000 in FY10fiscal year 2012 from $9,143,000$8,739,000 in FY09.  Sales from pharmaceutical software and services increased approximately $1,320,000, or 20.9%; and Words+’s sales increased approximately $249,000, or 2.4%, for the year.FY11. We attribute the increase in pharmaceutical software sales to increases in the number of licenses with new and existing customers, as well as licensing of new modules to existing customers.  A price increase on pharmaceutical softwarecustomers, especially for our GastroPlus line of products institutedbecause it has more modules than other products we offer. In addition, in the second4th quarter (withwe began two funded collaborations that will expand the effect being seen primarilycapabilities of our GastroPlus software.

Those increases outweighed the decreases in the 3rdnet sales from previously large funded collaborations and 4th quarters) is an additional factor re sultinganalytical studies (large collaboration contracts were completed by August 2010), workshops, and a Small Business Innovation Research Grant (2-year grant from NIH ended in increased revenues, accounting for approximately 20% of the $1,320,000 increase.  March 2011.)

The other 80% increase is a result of increases in number ofrevenue from software licenses resulted in an increase of $8,002,000, or 12.4%, while the revenue from services, such as funded collaborations contracts, grant, and analytical study contracts, and grant revenue.  We attribute the increaseresulted in Words+ sales to our “Conversa” product with preloaded “Say-it! SAM” software and our new EyePro product.  Increased revenues from these products outweighed decreased revenues from other products.


a decrease of $281,000, or 38.2%.

Cost of Sales

Consolidated

Cost of sales decreased $49,000, or 3.1%, to $1,510,000 in FY12 from $1,559,000 in FY11. As a percentage of net sales, cost of sales increased $225,000, or 9.7%, to $2,546,000 in FY10 from $2,321,000 in FY09, however, as a percentage of revenue, cost of salesalso decreased 1.6%by 1.8%.  For pharmaceutical software and services, cost of sales increased $140,000, or 13.0%, however, as a percentage of revenue, cost of sales decreased to 15.9% in FY10 from 17.0% in FY09.  

A significant portion of cost of sales for pharmaceutical software products is the systematic amortization of capitalized software development costs, which is an independent fixed cost rather than a variable cost related to sales. This amortization cost increased approximately $124,000,$7,000, or 1%, in FY12 compared with FY11.

Royalty expense, a variable cost related to sales of our GastroPlus core program as well as royalties from the agreement with Accelrys, Inc. (the original agreement was with Symyx Technologies which merged with Accelrys, Inc. in 2010) Metabolite/Metabolism, decreased approximately $26,000, or 5%, in FY12 compared with FY11. We also incurred royalty expense on the Enslein Metabolism Module; however, we signed an agreement to buy out this royalty agreement from Enslein Research of Rochester, New York on February 28, 2012 for $75,000, and as a result, we no longer had this royalty expense beginning March 2012.

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Service cost, such as labor costs for trainings/workshops, analytical studies, and technical support, decreased approximately $85,000, or 26%, in FY10FY12 compared with FY09.  Royalty expense, another significant portionFY11 as a result of costa lesser number of sales, increased approximately $28,000, or 7%, in FY10person-hours allocated to those services during FY12 compared with FY09.  We pay a royalty on GastroPlus basic software sales but not on its modules.  We also pay royalties on the Enslein Metabolism Module in our ADMET Predictor software in accordance with our agreement with Enslein Research, Inc.


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For Words+, cost of sales increased $85,000, or 6.8%, and as a percentage of revenue, cost of sales were almost the same with a slight decrease of 0.8% to 43.1% in FY10 from 43.9% in FY09.

FY11.

Gross Profit

Consolidated gross

Gross profit increased $1,344,000,$759,000, or 19.7%10.6%, to $8,166,000$7,939,000 in FY10FY12 from $6,822,000$7,180,000 in FY09.FY11. We attribute this increase to the increased sales of pharmaceutical software and servicesa decrease in addition to increased sales of Words+ products, which was greater than the increase in cost of goods sold.


Selling, General and Administrative Expenses

Selling, general and administrative (“SG&A”) expenses for FY10 increased by $429,000,$193,000, or 11.0%,6.1% to $4,325,000,$3,379,000 in FY12, compared to $3,896,000 for FY09. As$3,186,000 in FY11; however, as a percentage of sales, SG&A expenses decreased to 40.4%approximately 35.8% in FY12 from 42.6%approximately 36.5% in FY09. For Simulations Plus,FY11. The increase in SG&A expenses increased $242,000, or 10.4%.  As a percentageis due to an increase in the amount of sales, SG&A for Simulations Plus decreasedour office rent to 33.7%$293,000 from 36.9%. The major increases in expenses were accounting fees incurred for filing$144,000, because we now pay the entire office lease following the sale of amended tax returns, valuation services and travel expenses associated with investigating potential acquisitions, investor relations, selling expenses asour former subsidiary, Words+, on November 30, 2011. Although we continue to attendsublease approximately 20% of the office space to Words+, the income from the sublease is recorded as Other Income and so does not directly offset the increase in SG&A. Other increases in SG&A expense were due to increases in the costs associated with advertising, trade shows, marketing and labor, as we attended more trade shows and salaryconferences in FY12, we also contracted additional labor, were subject to a new tax on sales generated in India which the Indian government regulates, and had additional payroll-related expenses.


For Words+, expenses, increased by $188,000, or 12.0% due to increases in travel, commissions, salariessuch as payroll taxes, 401k and payroll-related expenses.insurances. These increases outweighed decreased in allowances for bad debts.

consulting fees, equipment rental, and recruiting costs.

Research and Development

We incurred approximately $1,857,000$1,900,000 of research and development (“R&D”) costs during FY10.FY12. Of this amount, $887,000$952,000 was capitalized and $970,000$948,000 was expensed as R&D.  As we record hours spent for studies, $175,000 was expensed as cost of sales.  During FY09expensed. In FY11, we incurred approximately $1,788,000$1,261,000 of research and development costs, of which approximately $674,000$797,000 was capitalized and approximately $1,114,000$464,000 was expensed. The hours spent for studies during FY09 was expensed as costincrease of sales which amounted $187,000.  The 4.9% increase$639,000, or 50.7%, in total research and development expenditureexpenditures from FY09FY11 to FY10FY12 was due to new hireslaboratory experimental costs of $140,000 for our NCE (new chemical entity) malaria project, staff increases, and salary increases for existing employees, which outweighed a reduced allocation of part of our CEO’s salary that had been spent on R&D, reflecting changes in his activities to a greater focus on business development and other administrative duties.


staff.

Income from operations

During FY10,FY12, we generated income from operations of $2,871,000,$3,612,000, as compared to $1,812,000$3,530,000 for FY09,FY11, an increase of 58.4%2.3%. We attribute this increase to increases in revenue from both pharmaceutical softwaregross profit and services and Words+ operations, and a decreasedecreases in R&D expenses, which was greater than the increases in cost of goods sold which outweighed increases in SG&A expenses,expense and sellingresearch and general administrativedevelopment expenses.


Other Income and (Expense)

The net of

Net other income over other expense for FY10(expense) increased by $18,000,$175,000, or 8.9%104.2%, to $233,000, compared to $215,000 for FY09.$343,000 in FY12 from $168,000 in FY11. This is due to increased interest income on money market accountsgains from Japanese Yen and gains onChinese Yuan currency exchange.


exchanges and sublease payments we received from Words+ for their rented space.

Provision for Income Taxes

Provision for income taxes for FY10FY12 increased by $333,000,$108,000, or 54.3%10.4%, to $948,000,$1,143,000, compared to $615,000$1,035,000 for FY09FY11 due to our estimation of higher provision for income taxthe increase in FY10.net income. The tax rate used in this report is lower than the standard rate because of various tax credits generated during the reporting period for this reporting period.


Annual Report on Form 10-K.

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Net

Income

from Continuing Operations

Net income from continuing operations for FY10FY12 increased by $744,000,$149,000, or 52.7%5.6%, to $2,156,000,$2,812,000, compared to $1,412,000$2,663,000 for FY09.FY11. We attribute this increase in net income to increased sales for both companiesgross profit and other income, and decreased R&D expense which was greater than theoutweighed increases in cost of goods sold, SG&A expenses and taxes.


SEASONALITY

Seasonality

Sales in the pharmaceutical products and servicesour business segment  (“Simulations Plus” in the table below) exhibit some seasonal fluctuations, with the fourth fiscal quarter (June-August) generally having the lowest sales over the past three fiscal years because of summer vacations and reduced activities at our customer’scustomers’ sites. This unaudited net sales information has been prepared on the same basis as the annual information presented elsewhere in this Annual Report on Form 10-K and, in the opinion of management, reflects all adjustments (consisting of normal recurring entries) necessary for a fair presentation of the information presented. Net sales for any quarter are not necessarily indicative of sales for any future period; however, because our pharmaceutical software is l icensedlicensed on an annual basis, renewals are almost alwaysgenerally within the same quarter year after year.

  
Net Simulations Plus Sales (in thousands)
 
FY 
First
Quarter
  
Second
Quarter
  
Third
Quarter
  
Fourth
Quarter
  Total 
2010  1,735   2,227   2,325   1,334   7,621 
2009  1,430   1,779   1,985   1,107   6,301 
2008  1,438   1,550   1,975   1,092   6,055 
2007  824   1,808   1,659   1,465   5,756 
2006  199   884   1,096   1,007   3,186 
2005  524   410   662   473   2,069 
2004  642   742   603   869   2,856 
2003  507   582   614   1,403   3,106 
2002  390   554   504   595   2,043 
2001  221   373   305   282   1,181 
2000  151   467   143   174   935 
1999  87   93   117   164   461 
1998  11   11   13   27   62 


Sales of our disability products business segment (“Words+”) to schools were slightly seasonal prior to our fiscal year ended August 31, 2006, with greater sales to schools during our third

  Net Sales (in thousands) 
FY First
Quarter
  Second
Quarter
  Third
Quarter
  Fourth
Quarter
  Total 
                
2012  2,248   2,789   2,772   1,640   9,449 
2011  2,050   2,622   2,640   1,427   8,739 
2010  1,735   2,227   2,325   1,334   7,621 
2009  1,430   1,779   1,985   1,107   6,301 
2008  1,438   1,550   1,975   1,092   6,055 
2007  824   1,808   1,659   1,465   5,756 
2006  199   884   1,096   1,007   3,186 
2005  524   410   662   473   2,069 
2004  642   742   603   869   2,856 
2003  507   582   614   1,403   3,106 
2002  390   554   504   595   2,043 
2001  221   373   305   282   1,181 
2000  151   467   143   174   935 
1999  87   93   117   164   461 
1998  11   11   13   27   62 

Liquidity and fourth fiscal quarter (March-May and June-August), as shown in the table below.



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   Net Words+ Sales (in thousands) 
FY 
First
Quarter
  
Second
Quarter
  
Third
Quarter
  
Fourth
Quarter
  Total 
2010  702   723   794   872   3,091 
2009  704   678   728   732   2,842 
2008  545   630   994   744   2,913 
2007  632   726   972   772   3,102 
2006  620   598   692   759   2,669 
2005  543   622   762   757   2,684 
2004  497   626   630   598   2,351 
2003  571   538   646   624   2,379 


LIQUIDITY AND CAPITAL RESOURCES
Capital Resources

Our principal source of capital has been the cash flow from our operations. We have achieved continuous positive operating cash flow over the last eightnine fiscal years. We believe that our existing capital and anticipated funds from operations will be sufficient to meet our anticipated cash needs for working capital and capital expenditures for the foreseeable future. Thereafter, if cash generated from operations is insufficient to satisfy our capital requirements, we may open a revolving line of credit with a bank, or we may have to sell additional equity or debt securities or obtain expanded credit facilities. In the event such financing is needed in the future, there can be no assurance that such financing will be available to us, or, if available, that it will be in amounts and on t ermsterms acceptable to us. If cash flows from operations became insufficient to continue operations at the current level, and if no additional financing was obtained, then management would restructure the Company in a way to preserve its pharmaceutical and disability businesses while maintaining expenses within operating cash flows.


We are not aware of any trends or demands, commitments, or uncertainties that are reasonably likely to result in a decrease in liquidity of our assets. The trend over the last eightten years has been increasing cash deposits from our operating cash flows, and we expect that trend to continue for the foreseeable future. We have no material commitments for capital expenditures as of the end of the latest fiscal period. We plan to continue our share repurchase program through the ending date of February 15, 2011; however, the exact amount of shares to be repurchased will depend on current market conditions and share prices on the NASDAQ stock exchange. If we repurchase all of the remaining 381,971 authorized shares (as of November 19, 2010) prior to February 15, 2011, at the current share price as of November 26, 2010, approximately $1.1 million in cash would be used.  This would be offset by the additional cash flow, if any, generated from operations prior to February 15, 2011.

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We continue to seek opportunities for strategic acquisitions. If one or more such acquisition is identified, a substantial portion of our cash reserves may be required to complete it; however, we intend to maintain sufficient cash reserves after any acquisition to provide reasonable assurance that outside financing will not be necessary to continue operations. If we identify an attractive acquisition that would require more cash to complete than we are willing or able to use from our cash reserves, we will consider financing options to complete the acquisition, including obtaining loans and issuing additional securities.


Because we have not been able to find suitable acquisitions for several years, the board of directors decided to distribute a portion of our cash reserves to our shareholders, declaring an ongoing $0.05 per share per quarter cash dividend beginning with the second quarter of FY12. Quarterly dividend payments were made on March 1, May 8, and August 10, 2012 during FY12. There can be no assurances that our Board of Directors will continue the dividend distributions for any specified number of quarters; however, there is no current plan to discontinue the quarterly dividend distributions.

UNUSUAL OR INFREQUENT EVENTS

There have been no unusual or infrequent events or other significant economic changes that have affected reported income.

On November 30, 2011, we sold our entire interest in our former wholly-owned subsidiary, Words+, an augmentative and alternative communication device manufacturer, for aggregate gross proceeds of $1.97 million. We recognized a gain of approximately $465,820, net of tax, from the sale of Words+, which is included in discontinued operations in our statement of operations for the fiscal year ended August 31, 2012. The difference between the sales price and the net gain is a result of adjustments to net working capital from August 31, 2011, until the closing on November 30, 2011, legal fees, auditing fees, tax specialist’s fees, and severance compensation for terminated employees.

KNOWN TRENDS OR UNCERTAINTIES

We are

Although we have not aware ofseen any trends or uncertainties expectedsignificant reduction in revenues to impact net sales or revenues from continuing operations. The recent trend towarddate, we have seen consolidation in the pharmaceutical industry during the current economic downturn. This trend has not had a negative effect on our total sales to that industry; however, these consolidations and downsizing in the industry could have an impact on our revenues and weearnings going forward.

We believe that the need for improved productivity in the research and development activities directed toward developing new medicines will continue to result in increasing adoption of simulation and modeling tools such as those we produce. For Words+, the ability of government agencies to continue to fund assistive technology for the disabled may be impacted by the current financial difficulties within federal, state, and local governments; however, we are not aware of any reductions in such funding to date.


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New product developments in both the pharmaceutical and disability business segments could result in increased revenues and earnings if they are accepted by our markets; however, there can be no assurances that new products will result in significant improvements to revenues or earnings. For competitive reasons, we do not disclose all of our new product development activities.

Our continued quest for acquisitions in the pharmaceutical business segment could result in a significant change to revenues and earnings if one or more such acquisitions isare completed. It is our intent to only complete acquisitions that would add to both revenues and earnings; however, there can be no assurances that any acquisitions that may be completed will in fact result in both increased revenues and earnings.


EFFECT OF CHANGING PRICES
A price increase on most of our pharmaceutical software products instituted in January 2010 has resulted in a contribution to increased revenues in that business segment. We attribute approximately 20% of the increased revenues in the pharmaceutical business segment for the fourth fiscal quarter of FY10 to these price increases, and the remaining 80% to new business.

INFLATION

We have not been affected materially by inflation during the periods presented, and no material effect is expected in the near future.


OFF-BALANCE SHEET ARRANGEMENTS

As of August 31, 2010,2012, we did not have any relationships with unconsolidated entities or financial partnerships, such as entities often referred to as structured finance or special purpose entities, which would have been established for the purpose of facilitating off-balance sheet arrangements or other contractually narrow or limited purposes. As such, we are not materially exposed to any financing, liquidity, market or credit risk that could arise if we had engaged in such relationships.

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We do not have relationships or transactions with persons or entities that derive benefits from their non-independent relationship with us or our related parties.


RECENTLY ISSUED or Newly adopted ACCOUNTING STANDARDS

In September 2009, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) 2009-14 which amends Statement of Position (“SOP”) 97-2, “Software Revenue Recognition”, to exclude tangible products containing software components and non-software components that function together to deliver the product’s essential functionality. ASU 2009-14 applies to revenue arrangements entered into or materially modified in fiscal years beginning on or after June 15, 2010, with early application permitted with Emerging Issues Task Force (“EITF”) 08-1.EITF 08-1 (as defined below). We expect to adoptadopted this standard in the first quarter of fiscal 2011. We are currently evaluating the impact ASU 2009-14 willbelieve adoption did not have a material effect on our consolidated fin ancialfinancial statements.


In September 2009, the FASB issued ASU 2009-13, “Revenue Arrangements with Multiple Deliverables” (“EITF 08-1”). ASU 2009-13EITF 08-1 amends EITFEmerging Issues Task Force (“EITF”) 00-21, “Revenue Arrangements with Multiple Deliverables”, to require an entity to use an estimated selling price when vendor-specific objective evidence or acceptable third-party evidence does not exist for any products or services included in a multiple element arrangement. The arrangement consideration should be allocated among the products and services based upon their relative selling prices, thus eliminating the use of the residual method of allocation. ASU 2009-13EITF 08-1 also requires expanded qualitative and quantitative disclosures regarding significant judgments made and changes in applying the guidance.  60;ASU 2009-13EITF 08-1 applies to fiscal years beginning after June 15, 2010, with early application permitted. We expect to adoptadopted this standard in the first quarter of fiscal 2011. We are currently evaluating the impact ASU 2009-13 willbelieve adoption did not have a material effect on our consolidated financial statements.

In May 2011, the FASB issued ASU 2011-04,Fair Value Measurement (“ASU 2011-04”), which amendedAccounting Standard Codification(“ASC”) 820,Fair Value Measurements(“ASC 820”), providing a consistent definition and measurement of fair value, as well as similar disclosure requirements between U.S. generally accepted account principals and International Financial Reporting Standards. ASU 2011-04 changes certain fair value measurement principles, clarifies the application of existing fair value measurement and expands the disclosure requirements. We adopted this standard in the first quarter of 2012. We believe adoption did not have a material effect on our financial statements.

In June 2011, the FASB issued ASU 2011-05,Presentation of Comprehensive Income (“ASU 2011-05”). ASU 2011-05 requires the presentation of comprehensive income in either (1) a continuous statement of comprehensive income or (2) two separate but consecutive statements. We adopted this standard in the first quarter of 2012. We believe adoption did not have a material effect on our financial statements.

In September 2011, the FASB issued ASU 2011-08,Testing Goodwill for Impairment (“ASU 2011-08”), which amends the guidance in ASC 350-20,Intangibles—Goodwill and Other – Goodwill. ASU 2011-08 provides entities with the option of performing a qualitative assessment before calculating the fair value of the reporting unit when testing goodwill for impairment. If the fair value of the reporting unit is determined, based on qualitative factors, to be more likely than not less than the carrying amount of the reporting unit, the entities are required to perform a two-step goodwill impairment test. We adopted this standard in the first quarter of 2012. We believe adoption did not have a material effect on our financial statements.

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CRITICAL ACCOUNTING POLICIES
Our consolidated

In December 2011, the FASB issued ASU No. 2011-11, “Disclosures about Offsetting Assets and Liabilities.” The amendments in this update require enhanced disclosures around financial statementsinstruments and accompanying notesderivative instruments that are preparedeither (1) offset in accordance with accounting principles generally acceptedeither ASC 210-20-45 or ASC 815-10-45 or (2) subject to an enforceable master netting arrangement or similar agreement, irrespective of whether they are offset in accordance with either ASC 210-20-45 or ASC 815-10-45. An entity should provide the disclosures required by those amendments retrospectively for all comparative periods presented. The amendments are effective during interim and annual periods beginning after February 28, 2012. We adopted this standard in the United Statesthird quarter of America.  Preparing2012. We believe adoption did not have a material effect on our financial statements requires managementstatements.

In July 2012, the FASB issued ASU 2012-02, “Testing Indefinite-Lived Intangible Assets for Impairment”, which amended the guidance in ASU 2011-08 to make estimatessimplify the testing of indefinite-lived intangible assets other than goodwill for impairment. ASU 2012-02 becomes effective for annual and assumptions that affectinterim impairment tests performed for fiscal years beginning on or after September 15, 2012 and earlier adoption is permitted. We adopted this standard in the reported amountsfirst quarter of assets, liabilities, revenue, and expenses. These estimates and assumptions are affected by management’s application of accounting policies.  Critical accounting policies for us include revenue recognition, accounting for capitalized software development costs, and accounting for income taxes.


fiscal year 2013. We believe adoption did not have a material effect on our financial statements.

Revenue Recognition

We recognize revenuerevenues related to software licenses and software maintenance in accordance with the FASB Accounting Standard Codification (“ASC”) 985-605.  ProductASC 985-605,“Software – Revenue Recognition”. Software products revenue is recorded when the following conditions are met: 1) evidence of arrangement exists, such as signed purchase orders from customers or executed contracts,exists; 2) delivery has been made, such as unlocking the software on the customer’s computer(s),made; 3) the amount is fixed,fixed; and 4) itcollectability is collectible.probable. Post-contract customer support ("PCS"(“PCS”) obligations are insignificant; therefore, revenue for PCS is recognized at the same time as the licensing fee, and the costs of providing such support services are accrued and amortized over the obligation period.


As a byproduct of ongoing improvements and upgrades to ourfor the new programs and new modules of software, some modifications are provided to our customers who have already licensedpurchased software during their license term at no additional charge. Other software modifications result in new, additional cost modules that expand the functionality of the software. These are licensed separately. We consider thesethe modifications that are provided without charge to be minimal, as they aredo not changingsignificantly change the basic functionality or utility of the software, but rather addingadd convenience, such as being able to plot some additional variable on a graph in addition to the numerous variables that had been available before.before, or adding some additional calculations to supplement the information provided from running the software. Such software modifications for any single product have been typically occurred once or twice per year, sometimes more, sometimes less. Thus, they are infrequent. We provide,The Company provides, for a fee, additional training and service calls to ourits customers and recognizerecognizes revenue at the time the training or service call is provided.


We

Generally, we enter into one-year license agreements with most of our customers for the use of our pharmaceutical software products. However,We recognize revenue on these contracts when all the criteria are met.

Most license agreements have a term of one year; however, from time to time, we enter into multi-year license agreements. We generally unlock and invoice software one year at a time for multi-year licenses. Therefore, revenue is recognized one year at a time.


We recognize the revenue from collaboration research and the revenue from grants equally over their terms. However, we recognize the contract study revenue either equally over the term of the contract or using the percentage of completion method, depending upon how the contract studies are engaged, in accordance with FASB ASC 605-35.  605-35,“Revenue Recognition – Construction-Type and Production-Type Contracts”.To recognize revenue using the percentage of completion method, we must determine whether we meet the following criteria: 1) there is a long-term, legally enforceable contract and 2) it is possible to reasonably estimate the total project costs, and 3) it is possible to reasonably estimate the extent of progress toward completion.

18

Capitalized Computer Software Development Costs

Software development costs are capitalized in accordance with FASB ASC 985-20.985-20,“Costs of Software to Be Sold Leased, or Marketed”. Capitalization of software development costs begins upon the establishment of technological feasibility and is discontinued when the product is available for sale.


The establishment of technological feasibility and the ongoing assessment for recoverability of capitalized software development costs require considerable judgment by management with respect to certain external factors including, but not limited to, technological feasibility, anticipated future gross revenues, estimated economic life, and changes in software and hardware technologies. Capitalized computer software development costs are comprised primarily of salaries and direct payroll-related costs and the purchase of existing software to be used in ourthe Company’s software products.


20



Amortization of capitalized computer software development costs is provided on a product-by-product basis on the straight-line method over the estimated economic life of the products (not to exceed five years). Amortization of software development costs amounted to $644,014$668,021 and $519,415$660,893 for the fiscal years ended August 31, 20102012 and 2009,2011, respectively. We expect future amortization expense to vary due to increases in capitalized computer software development costs.


We test capitalized computer software development costs for recoverability whenever events or changes in circumstances indicate that the carrying amount may not be recoverable within a reasonable time.


recoverable.

Income Taxes

We utilize FASB ASC 740-10,“Income Taxes”,which requires the recognition of deferred tax assets and liabilities for the expected future tax consequences of events that have been included in the financial statements or tax returns.


Under this method, deferred income taxes are recognized for the tax consequences in future years of differences between the tax bases of assets and liabilities and their financial reporting amounts at each year-end based on enacted tax laws and statutory tax rates applicable to the periods in which the differences are expected to affect taxable income. Valuation allowances are established, when necessary, to reduce deferred tax assets to the amount expected to be realized. The provision for income taxes represents the tax payable for the period and the change during the period in deferred tax assets and liabilities.


Stock-Based Compensation

The Company accountsWe account for stock options using the modified prospective method in accordance with FASB ASC 718-10,“Compensation-Stock Compensation”. Under this method, compensation costs includes:include: (1) compensation cost for all share-based payments granted prior to, but not yet vested as of September 1, 2006, based on the grant dategrant-date fair value estimated in accordance with the original provisions of SFASStatement of Financial Accounting Standards No. 123 amortized over the options’ vesting period, and (2) compensation cost for all share-based payments granted subsequent to September 1, 2006, based on the grant-date fair value estimated in accordance with the provisions of FASB ASC 718-10,, amortized on a straight-line basis over the options’ vesting period.


Principles Stock-based compensation was $181,520 and $155,252 for the fiscal years ended August 31, 2012 and 2011, respectively, and is included in the consolidated statements of Consolidation
The consolidated financial statements include the accounts of Simulations Plus, Inc.operations as Consulting, Salaries, and its wholly owned subsidiary, Words+, Inc.  All significant intercompany accountsResearch and transactions are eliminated in consolidation.

Development expense.

Estimates

Our consolidated financial statements and accompanying notes are prepared in accordance with accounting principles generally accepted in the United States of America. Preparing financial statements requires management to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenue, and expenses. These estimates and assumptions are affected by management’s application of accounting policies. Actual results could differ from those estimates. Significant accounting policies for us include revenue recognition, accounting for capitalized software development costs, and accounting for income taxes.

19

ITEM 7A

Item 7a – QUANTITATIVE AND QUALITATIVEQUALitaTiVe DISCLOSURES ABOUT MARKET RISK


Not applicable because the Company iswe are a smaller reporting company.


21



ITEM

Item 8 - FINANCIAL STATEMENTSFinancial Statements AND SUPPLEMENTARY DATA


The responses to this item are included elsewhere in this Form 10-K (see pages F1 – F26)F23) and incorporated herein by reference.


ITEM

Item 9 – CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND FINANCIAL DISCLOSURE


Changes in and Disagreements with Accountants on Accounting and Financial Disclosure

There have been no changes to our public accountants during the past two years.


ITEM 9A – CONTROLS AND PROCEDURES


Disclosure Controls and Procedures

We are responsible for maintaining disclosure controls and procedures, as defined in Rules 13a-15(e) and 15d-15(e) under the Exchange Act.Exchange. Disclosure controls and procedures are controls and other procedures designed to ensureprovide reasonable assurance that the information required to be disclosed by us in the reports that we file or submit under the Exchange Act is recorded, processed, summarized, and reported within the time periods specified in the Securities and Exchange Commission’sSEC’s rules and forms. Disclosure controls and procedures include, without limitation, controls and procedures designed to ensure that information required to be disclosed by us in the reports that we file or submit under the Exchange Act is accumulated and communicated to our management, including our principal executive officer and principal financial offic erofficer, as appropriate, to allow timely decisions regarding required disclosure. In designing and evaluating disclosure controls and procedures, management recognizes that any controls and procedures, no matter how well designed and operated, can provide only reasonable assurance of achieving the desired control objectives, and management is required to apply its judgment in evaluating the cost-benefit relationship of possible controls and procedures.


Based on our management’s evaluation (with the participation of our principal executive officer and principal financial officer) of our disclosure controls and procedures as required by Rule 13a-1513a-15(b) and 15d-15(b) under the Exchange Act, our principal executive officer and principal financial officer have concluded that our disclosure controls and procedures were effective at the reasonable assurance level as of August 31, 2010,2012, the end of the fiscal year covered by this report.


Management's

Management’s Report on Internal Control overOver Financial Reporting

Our management is responsible for establishing and maintaining adequate internal controls over financial reporting, as defined in Exchange Act RuleRules 13a-15(f) and 15d-15(f). Our internal controls over financial reporting are designed to provide reasonable assurance regarding the reliability of financial reporting and the preparation of consolidated financial statements for external purposes in accordance with generally accepted accounting principles.

20

Under the supervision and with the participation of our management, including our Chief Executive Officerprincipal executive officer and Chief Financial Officer,principal financial officer, we conducted an evaluation of the effectiveness of our internal controls over financial reporting based on the framework established by the Committee of Sponsoring Organizations forof the Treadway Commission. Based on our evaluation under thesuch framework, including the completion and review of internal review assessment forms and the completion and review of financial reporting information systems and controls checklists in the framework, our management concluded that our internal control over financial reporting was effective as of August 31, 2010.


22


Because of the inherent limitations, internal control over financial reporting may not prevent or detect misstatements. Projections of any evaluation of effectiveness to future periods are subject to the risks that controls may become inadequate because of2012.

No changes in conditions or that the degree of compliance with the policies or procedures may deteriorate.


Changes in Internal Control over Financial Reporting
In connection with the evaluation required by Exchange Act Rule 13a-15(d), our management, including the Chief Executive Officer and Chief Financial Officer, concluded that no changes occurredwere made in our internal controls over financial reporting (as defined in Rules 13a-15(f) and 15d-15(f) of the Exchange Act) during our most recent fiscalthe quarter ended August 31, 2012, that have materially affected, or are reasonably likely to materially affect, our internal controls over financial reporting.

Our management, including our CEO and CFO, does not expect that our disclosure controls or internal controls over financial reporting will prevent all errors or all instances of fraud. A control system, no matter how well-designed and operated, can provide only reasonable, not absolute, assurance that the control system’s objectives will be met. Further, the design of a control system must reflect the fact that there are resource constraints, and the benefits of controls must be considered relative to their costs. Because of the inherent limitations in all control systems, no evaluation of controls can provide absolute assurance that all control issues and instances of fraud, if any, within our company have been detected. These inherent limitations include the realities that judgments in decision-making can be faulty, and that breakdowns can occur because of simple errors or mistakes. Controls can also be circumvented by the individual acts of some persons, by collusion of two or more people, or by management override of the controls. The design of any system of controls is based in part upon certain assumptions about the likelihood of future events, and any design may not succeed in achieving its stated goals under all potential future conditions. Over time, controls may become inadequate because of changes in conditions or deterioration in the degree of compliance with policies or procedures. Because of the inherent limitation of a cost-effective control system, misstatements due to error or fraud may occur and not be detected.

ITEM

Item 9B - OTHER INFORMATION


Other Information

Not applicable.



PART III


ITEM

Item 10 – DIRECTORS, AND EXECUTIVE OFFICERS,Directors, and Executive Officers, AND CORPORATE GOVERNANCE


Code of Ethics

We have adopted a

Our code of ethics which applies to allis posted on our employees, including our Chief Executive Officer, Chief Financial Officer and persons performing similar function. The full text of our code of ethics can be found in the “Investor ” section of our website accessible to the public at www.simulations-plus.com, by clicking the Corporate Overview link.


website: www.simulations-plus.com.

Changes to Procedures for Recommending Nominees to the Board of Directors

There have been no material changes to the procedures by which security holders may recommend nominees to our board of directors since we last described such procedures.


The remaining information required by Item 10 is incorporated by reference from the Company’ssections entitled “Board Matters and Corporate Governance,” “Election of Directors,” “Executive Compensation and Other Information,” and “Security Ownership of Certain Beneficial Owners and Management” in our definitive proxy statement on Schedule 14A (the “Proxy Statement”) for its 2011to be distributed in connection with our 2013 Annual Shareholders’ Meeting.

21

ITEM

Item 11 – EXECUTIVE COMPENSATION


Executive Compensation

The information required by Item 11 is incorporated by reference from the Company’ssections entitled “Executive Compensation and Other Information” and “Board Matters and Corporate Governance” in our Proxy Statement for its 2011to be distributed in connection with our 2013 Annual Shareholders’ Meeting.


ITEM

Item 12 - SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENTSecurity Ownership of Certain Beneficial Owners and Management AND RELATED STOCKHOLDER MATTERS


The information required by Item 12 is incorporated by reference from the Company’ssections entitled “Security Ownership of Certain Beneficial Owners and Management” and “Executive Compensation and Other Information” in our Proxy Statement for its 2011to be distributed in connection with our 2013 Annual Shareholders’ Meeting.


23



ITEM

Item 13 – CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS,Certain Relationships and Related Transactions, AND DIRECTOR INDEPENDENCE


The information required by Item 13 is incorporated by reference from the Company’ssubsection entitled “Certain Relationships and Related Transactions; Transactions with Related Persons” and the section entitled “Board Matters and Corporate Governance” in our Proxy Statement for its 2011to be distributed in connection with our 2013 Annual Shareholders’ Meeting.


ITEM

Item 14 – PRINCIPAL ACCOUNTING FEES AND SERVICES


principal accountING fees and services

The information required by Item 14 is incorporated by reference from the Company’ssection of the proposal entitled “Ratification of Selection of Independent Registered Public Accounting Firm” in our Proxy Statement for its 2011to be distributed in connection with our 2013 Annual Shareholders’ Meeting.



PART IV


ITEM 15 – EXHIBITS, FINANCIAL STATEMENT SCHEDULES


Exhibits, Financial Statement Schedules

(a)               (1) Financial Statements. The consolidated financial statements are included in this Annual Report.

(2) Financial Statement Schedules. All financial statement schedules have been omitted since the information is either not applicable or required or was included in the financial statements or notes included in this Annual Report on Form 10-K.

10-K

(3) List of Exhibits required by Item 601 of Regulation S-K. See part (b) below.

(b)              Exhibits. The following exhibits are filed as part of this report. Those exhibits marked with a (†) refer to management contracts or compensatory plans or arrangements.

EXHIBIT 
NUMBERDESCRIPTION
  
3.1Articles of Incorporation of Simulations Plus, Inc. (7)the Company. (5)
3.2Amended and Restated Bylaws of Simulations Plus, Inc. (7)the Company. (5)
4.1Articles of Incorporation of Simulations Plus, Inc.the Company. (incorporated by reference to Exhibit 3.1 hereof) and
4.2Bylaws of Simulations Plus, Inc.the Company. (incorporated by reference to Exhibit 3.2 hereof)
4.24.3Form of Common Stock Certificate (1)
4.34.4Share Exchange Agreement (1)
10.1
Simulations Plus, Inc.The Company’s 1996 Stock Option Plan (the “Option Plan”) and forms of agreements relating thereto (1) (†)
10.2410.2Exclusive License Software License Agreement by and between Simulations Plus, Inc.the Company and Therapeutic Systems Research Laboratories dated June 30, 1997. (2)
10.3410.3OEM/Remarketing Agreement between Words+, Inc. and Eloquent Technology, Inc. (6)The Company’s 2007 Stock Option Plan. (3)
10.4110.4Technology Transfer Agreement between Sam Communications, LLC. (6)
10.43Notice of Election to Extend Term of Lease Agreement by and between Simulations Plus, Inc.the Company and VentureCrest Development LLC formerly Freeway LLC. (3)Ventures LLC, dated July 29, 2010.(4)
10.4510.5
Employment Agreement by and between the Company and Walter S. Woltosz, (4)dated as of July 22, 2011. (5) (†)
10.4610.6
Simulations Plus, Inc. 2007 Stock Option Plan (the “2007 Option Plan”) (5 (†)
10.47Lease extension agreementBill of Sale by and between Simulations Plus,the Company and Entelos, Inc. and Crest Development (7)dated September 19, 2011. (6)
21.110.7List of SubsidiariesStock Purchase Agreement by and among the Company, Words+, Inc., and Prentke Romich Company dated November 15, 2011. (7)
23.1Consent of Rose, Snyder and Jacobs (7)Independent Registered Public Accounting Firm (8)
31.1Rule 13a-14(a)/15d-14(a)Section 302 – Certification of Chiefthe Principal Executive Officer (CEO). (7)Officer. (8)
31.2Rule 13a-14(a)/15d-14(a)Section 302 – Certification of Chiefthe Principal Financial Officer (CFO). (7)Officer. (8) 
3232.1Section 1350906 – Certification of CEOthe Chief Executive Office and CFO. (7)Chief Financial Officer.  (8)
101.INSXBRL Instance Document.*
101.SCHXBRL Taxonomy Extension Schema Document.*
101.CALXBRL Taxonomy Extension Calculation Linkbase Document.*
101.DEFXBRL Taxonomy Extension Definition Linkbase Document.*
101.LABXBRL Taxonomy Extension Label Linkbase Document.*
101.PREXBRL Taxonomy Extension Presentation Linkbase Document.*

 
________________

(1)Incorporated by reference to the Company’s Registration Statement on Form SB-2 (Registration No. 333-6680) filed on March 25, 1997.
(2)Incorporated by reference to the Company’s Form 10-KSB filed December 15, 1997 (Commission file No. 333-05400-LA).for the fiscal year ended August 31, 1997.
(3)Incorporated by reference to the Company’s Form 10-KSB filed December 15, 1997 (Commission file No. 333-05400-LA).10-K for the fiscal year ended August 31, 2009.
(4)Incorporated by reference to the Company’s Form 10-K filed November 30, 2010 (Commission file No. 001-32046).for the fiscal year ended August 31, 2010.
(5)Incorporated by reference to the Company’s Form 10-Q filed January 13, 2010 (Commission No. 001-32046)10-K for the fiscal year ended August 31, 2011.
(6)Incorporated by reference to the Company’s Form 10-K/A8-K filed on March 1, 2010 (Commission file No. 001-32046).September 22, 2011.
(7)Incorporated by reference to the Company’s Form 8-K filed November 16, 2011.
(8)Filed herewith

* Pursuant to Rule 405(a)(2) of Regulation S-T, the Company will furnish the XBRL Interactive Data Files with detailed footnote tagging as Exhibit 101 in an amendment to this Form 10-Q within the permitted 30-day grace period granted for the first quarterly period in which detailed footnote tagging is required.

(c)           Financial Statement Schedule.

See Item 15(a)(2) above.

23
 (7)Filed herewith.

(c)        Financial Statement Schedule.

See Item 15(a)(2) above.

24



SIGNATURES


In accordance with

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the Registrantregistrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Lancaster, State of California, on November 29, 2010.


13, 2012.

 SIMULATIONS PLUS, INC.
  
 By:/s/Momoko A. Beran 
 
By /s/ Momoko A. Beran                            
 Momoko A. Beran
 Chief Financial Officer


In accordance with

Pursuant to the requirements of the Securities Exchange Act of 1934, this report has been signed below by the following persons on behalf of the Registrantregistrant and in the capacities indicated on.



and on the dates indicated.

SignatureTitle
  
 
/s/Walter S. Woltosz
Chairman of the Board of Directors
Walter S. Woltoszand Chief Executive Officer (Principal executive officer)
  
/s/ Virginia E. Woltosz  
 
/s/Virginia E. WoltoszSecretary and Director of the Company
Virginia E. Woltosz
/s/ Dr. David Z. D’Argenio
Dr. David Z. D’ArgenioDirector
  
  
/s/ Dr. Richard R. Weiss
 
/s/Dr. Richard R. WeissDavid Z. D’ArgenioDirector
Dr. David Z. D’Argenio  
  
/s/ Dr. David L. RalphDirector
Dr. David L. Ralph
/s/ Harold W. Rosenberger 
Harold W. RosenbergerDirector
  
  
/s/ Momoko A. Beran
 
/s/Momoko A. BeranChief Financial Officer of the Company(Company
Momoko A. Beran(Principal financial officer and principal accounting officer)


SIMULATIONS PLUS, INC.

CONTENTS

August 31, 2012 and 2011

 
25


SIMULATIONS PLUS, INC. AND SUBSIDIARY
CONTENTS
August 31, 2010 and 2009


 Page
  
REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRMF2F-2
  
CONSOLIDATED FINANCIAL STATEMENTS 
  
Consolidated Balance SheetsF3F-3
  
Consolidated Statements of OperationsF4F-4
  
Consolidated Statements of Shareholders’ EquityF5F-5
  
Consolidated Statements of Cash FlowsF6F-6
  
Notes to Financial Statements F-7 – F-24
 Notes to Consolidated Financial StatementsF7 – F23






REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM




To the Board of Directors and Shareholders of

Simulations Plus, Inc.

Lancaster, California



We have audited the accompanying consolidated balance sheets of Simulations Plus, Inc. (a California corporation) and Subsidiary as of August 31, 20102012 and 20092011 and the related consolidated statements of operations, shareholders’ equity and cash flows for the years then ended. These consolidated financial statements are the responsibility of the Company’s management. Our responsibility is to express an opinion on these consolidated financial statements based on our audits.


We conducted our audits in accordance with the standards established by the Public Company Accounting Oversight Board (United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement. The Company is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. Our audits included consideration of internal control over financial reporting as a basis for designing audit procedures that are appropriate in the circumstances, but not for the purpose of expressing an opinion on the effectiveness of the Company’s internal control over financial reporting. Accordingly, we express no such opinion. An audit also includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements, assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audits provide a reasonable basis for our opinion.


In our opinion, the consolidated financial statements referred to above present fairly, in all material respects, the consolidated financial position of Simulation Plus, Inc. and Subsidiary as of August 31, 20102012 and 2009,2011, and the consolidated results of theirits operations and theirits cash flows for the years then ended in conformity with accounting principles generally accepted in the United States of America.




Rose, Snyder & Jacobs

A Corporation of Certified Public Accountants

LLP

Encino, California


November 26, 2010

13, 2012

SIMULATIONS PLUS, INC.

BALANCE SHEETS

For the years ended

 
F-2

SIMULATIONS PLUS, INC. AND SUBSIDIARY
CONSOLIDATED BALANCE SHEETS

ASSETS 
       
  August 31, 
  2010  2009 
Current assets      
Cash and cash equivalents $9,631,762  $7,473,485 
Income tax refund receivable  225,510   - 
Accounts receivable, net of allowance for doubtful accounts and estimated contractual discounts of $421,118 and $447,073  1,291,350   1,888,904 
Contracts receivable  184,081   79,565 
Inventory  554,867   325,926 
Prepaid expenses and other current assets  138,163   158,738 
Deferred income taxes  364,264   338,516 
Total current assets  12,389,997   10,265,134 
         
Capitalized computer software development costs,
        
net of accumulated amortization of $4,487,757 and $3,843,743  2,186,419   1,942,893 
Property and equipment, net (note 3)
  55,984   53,220 
Customer relationships, net of accumulated amortization of $118,442 and $104,728
  9,600   23,314 
Other assets  18,445   18,445 
         
Total assets $14,660,445  $12,303,006 
         
         
LIABILITIES AND SHAREHOLDERS' EQUITY 
Current liabilities        
Accounts payable $239,424  $199,218 
Accrued payroll and other expenses  511,106   552,431 
Accrued bonuses to officer  60,000   60,000 
Accrued income taxes  261,861   - 
Accrued warranty and service costs  35,586   43,236 
Deferred revenue  96,092   82,190 
Total current liabilities  1,204,069   937,075 
         
Long-term liabilities        
Deferred income taxes  410,523   795,140 
         
Total liabilities  1,614,592   1,732,215 
         
Commitments and contingencies (note 4)
        
         
Shareholders' equity (note 5)
        
Preferred stock, $0.001 par value 10,000,000 shares authorized no shares issued and outstanding  -   - 
Common stock, $0.001 par value 50,000,000 shares authorized 15,833,006 and 15,700,382 shares issued and outstanding  4,304   4,172 
Additional paid-in capital  5,891,268   5,572,411 
Retained earnings  7,150,281   4,994,208 
         
Total shareholders' equity  13,045,853   10,570,791 
         
Total liabilities and shareholders' equity $14,660,445  $12,303,006 

 August 31, 
ASSETS 2012  2011 
Current assets        
Cash and cash equivalents $12,701,075  $10,181,049 
Income tax refund receivable  153,896   259,434 
Accounts receivable, net of allowance for doubtful accounts of $0  1,451,864   1,170,861 
Contracts receivable  18,893   185,816 
Prepaid expenses and other current assets  150,856   123,954 
Deferred income taxes  193,712   302,076 
Current assets of discontinued operations     1,051,637 
Total current assets  14,670,296   13,274,827 
Long-term assets        
Capitalized computer software development costs,        
net of accumulated amortization of $5,084,690 and $4,416,669  2,479,468   2,188,982 
Property and equipment, net (note 3)  107,410   43,010 
Intellectual property, net of accumulated amortization of $3,750  71,250    
Customer relationships, net of accumulated amortization of $128,042 and $126,172     1,870 
Other assets  18,445   18,445 
Non-current assets of discontinued operations     340,204 
Total assets $17,346,869  $15,867,338 
         
LIABILITIES AND SHAREHOLDERS' EQUITY        
Current liabilities        
Accounts payable $177,509  $176,136 
Accrued payroll and other expenses  312,912   276,327 
Accrued bonuses to officer  60,000    
Accrued income taxes  733,233   168,897 
Deferred revenue  131,782   141,191 
Current liabilities of discontinued operations     378,567 
Total current liabilities  1,415,436   1,141,118 
         
Long-term liabilities        
Deferred income taxes  788,857   656,047 
Non-current liabilities of discontinued operations     33,558 
Total liabilities  2,204,293   1,830,723 
         
Commitments and contingencies(note 4)        
         
Shareholders' equity (note 5)        
Preferred stock, $0.001 par value 10,000,000 shares authorized no shares issued and outstanding      
Common stock, $0.001 par value 50,000,000 shares authorized 15,923,019 and 15,572,943 shares issued and outstanding  4,399   4,044 
Additional paid-in capital  4,628,366   4,167,650 
Retained earnings  10,509,811   9,864,921 
Total shareholders' equity  15,142,576   14,036,615 
         
Total liabilities and shareholders' equity $17,346,869  $15,867,338 

The accompanying notes are an integral part of these consolidated financial statements.

F-3

SIMULATIONS PLUS, INC. AND SUBSIDIARY

CONSOLIDATED

STATEMENTS OF OPERATIONS

For the years ended


  August 31, 
  2010  2009 
       
Net sales $10,711,829  $9,143,271 
         
Cost of sales  2,545,709   2,321,592 
         
Gross profit  8,166,120   6,821,679 
         
Operating expenses        
Selling, general, and administrative  4,325,621   3,895,995 
Research and development  969,871   1,113,855 
         
Total operating expenses  5,295,492   5,009,850 
         
Income from operations  2,870,628   1,811,829 
         
Other income (expense)        
Interest income  101,545   93,874 
Miscellaneous income  1,231   607 
Gain on currency exchange  130,150   120,350 
Gain on sale of assets  1,993   - 
Interest expense  (1,045)  - 
         
Total other income (expense)  233,874   214,831 
         
Income before income taxes  3,104,502   2,026,660 
         
Provision for income taxes        
Deferred income taxes  (289,829)  (32,628)
Current Income taxes  (658,600)  (581,948)
         
Net income $2,156,073  $1,412,084 
         
Basic earnings per share $0.14  $0.09 
         
Diluted earnings per share $0.13  $0.08 
         
Weighted-average common        
shares outstanding        
         
Basic  15,831,294   16,126,471 
         
Diluted  16,513,018   17,187,547 

 

  August 31, 
  2012  2011 
       
Net sales $9,448,608  $8,738,739 
Cost of sales  1,510,148   1,558,178 
Gross profit  7,938,460   7,180,561 
Operating expenses        
Selling, general, and administrative  3,379,017   3,185,999 
Research and development  947,556   464,281 
Total operating expenses  4,326,573   3,650,280 
         
Income from operations  3,611,887   3,530,281 
         
Other income (expense)        
Interest income  89,265   91,224 
Miscellaneous income  76,149    
Gain on currency exchange  177,790   76,416 
Gain on sale of assets  (433)  240 
Interest expense  (3)  (43)
Total other income (expense)  342,768   167,837 
         
Income from continuing operations before provision for income taxes  3,954,655   3,698,118 
         
Provision for income taxes(note 6)  (1,142,693)  (1,035,473)
         
Income from continuing operations $2,811,962  $2,662,645 
         
Discontinued operations:        
Gain (loss) from discontinued operations, net of tax  (249,898)  51,996 
Gain on sale of Words+, net of tax  465,820    
Results of discontinued operations  215,922   51,996 
         
Net Income $3,027,884  $2,714,641 
         
Basic earnings per share:        
Continuing operations $0.18  $0.17 
Discontinued operations  0.01   0.00 
Net basic earning per share $0.19  $0.17 
Diluted earnings per share        
Continuing operations $0.18  $0.17 
Discontinued operations  0.01   0.00 
Net basic earning per share $0.19  $0.17 
         
Weighted-average common shares outstanding        
Basic  15,763,674   15,540,047 
Diluted  16,151,873   16,082,454 

The accompanying notes are an integral part of these consolidated financial statements.

F-4

SIMULATIONS PLUS, INC. AND SUBSIDIARY

CONSOLIDATED

STATEMENTS OF SHAREHOLDERS' EQUITY

For the years ended August 31,



        Additional       
  Common Stock  Paid-In       
  Shares  Amount  Capital  Retained Earnings  Total 
                
Balance, August 31, 2008  16,297,400   4,769   6,328,185   3,582,124   9,915,078 
                     
Exercise of stock options  249,824   250   124,514       124,764 
                     
Stock-based Compensation          183,294       183,294 
                     
Stock Repurchases  (846,842)  (847)  (1,063,582)      (1,064,429)
          ��          
Net income              1,412,084   1,412,084 
                     
Balance, August 31, 2009  15,700,382  $4,172  $5,572,411  $4,994,208  $10,570,791 
                     
Exercise of stock options  632,674   632   94,290       94,922 
                     
Stock-based Compensation          127,597       127,597 
                     
Stock Repurchases  (500,050)  (500)  (1,033,607)      (1,034,107)
                     
Deferred tax adjustments          1,130,577       1,130,577 
                     
Net income              2,156,073   2,156,073 
                     
Balance, August 31, 2010  15,833,006  $4,304  $5,891,268  $7,150,281  $13,045,853 

 

  Common Stock  Additional Paid-In  Retained    
  Shares  Amount  Capital  Earnings  Total 
                     
Balance, August 31, 2010  15,833,006  $4,304  $5,891,268  $7,150,280  $13,045,852 
                     
Exercise of stock options  415,776   416   144,545       144,961 
                     
Stock-based Compensation          155,252       155,252 
                     
Stock Repurchases  (675,839)  (676)  (2,047,496)      (2,048,172)
                     
Deferred tax adjustments          24,081       24,081 
                     
Net income              2,714,641   2,714,641 
                     
Balance, August 31, 2011  15,572,943  $4,044  $4,167,650  $9,864,921  $14,036,615 
                     
Exercise of stock options  354,863   355   301,286       301,641 
                     
Stock-based Compensation          181,521       181,521 
                     
Deferred tax adjustments                    
- Change in prior year tax refund          (36,868)      (36,868)
                     
- Current deferred tax adjustments          14,777       14,777 
                     
Declaration of Dividend              (2,382,994)  (2,382,994)
                     
Net income              3,027,884   3,027,884 
                     
Balance, August 31, 2012  15,927,806  $4,399  $4,628,366  $10,509,811  $15,142,576 

The accompanying notes are an integral part of these consolidated financial statements.

F-5

SIMULATIONS PLUS, INC. AND SUBSIDIARY

CONSOLIDATED

STATEMENTS OF CASH FLOWS

For the years ended


 
  August 31, 
  2010  2009 
Cash flows from operating activities      
Net income $2,156,073  $1,412,084 
Adjustments to reconcile net income to net cash provided by operating activities
        
Depreciation and amortization of property and equipment  25,215   21,893 
Amortization of customer relationships  13,714   19,699 
Amortization of capitalized computer software development costs  644,014   519,415 
Bad debts  176,978   219,998 
Excess tax benefits from share-based arrangements  (1,130,577)  - 
Stock-based compensation  127,597   183,294 
Gain on sale of equipment  (1,993)  - 
Deferred income taxes  289,829   32,628 
(Increase) decrease in        
Accounts receivable and Contracts receivable  335,216   (83,397)
Income tax refundable  298,641   - 
Inventory  (228,940)  88,205 
Prepaid expenses and other assets  24,532   36,592 
Increase (decrease) in        
Accounts payable  42,741   17,988 
Accrued payroll and other expenses  (41,327)  15,068 
Accrued income taxes  167,993     
Accrued warranty and service costs  (7,651)  9,337 
Deferred revenue  13,902   (1,143)
         
Net cash provided by operating activities  2,905,957   2,491,661 
         
Cash flows from investing activities        
Purchases of property and equipment  (51,532)  (44,560)
Proceeds from sale of investments  -   750,000 
Capitalized computer software development costs  (887,541)  (673,552)
         
Net cash provided by (used in) investing activities  (939,073)  31,888 
         
Cash flows from financing activities        
Repurchase of common stock  (1,034,106)  (1,064,429)
Excess tax benefits from share-based arrangements  1,130,577   - 
Proceeds from the exercise of stock options  94,922   124,764 
         
Net cash provided by (used in) financing activities  191,393   (939,665)
         
Net increase in cash and cash equivalents $2,158,277  $1,583,884 
         
Cash and cash equivalents, beginning of year  7,473,485   5,889,601 
         
Cash and cash equivalents, end of period $9,631,762  $7,473,485 
         
Supplemental disclosures of cash flow information        
         
Interest paid $1,045  $- 
         
Income taxes paid $390,696  $549,122 

  2012  2011 
Cash flows from operating activities        
Net income $3,027,884  $2,714,641 
Adjustments to reconcile net income to net cash provided by operating activities        
(Income) from Discontinued Operations  (215,922)  (51,996)
Depreciation and amortization of property and equipment  41,802   21,822 
Amortization of customer relationships  1,871   7,730 
Amortization of capitalized computer software development costs  668,021   660,893 
Amortization of Intellectual property  3,750    
Excess tax benefits from share-based arrangement  22,091   (24,081)
Stock-based compensation  127,738   155,253 
(Gain)/Loss from sale of assets  433   (240)
Deferred income taxes  207,617   307,712 
(Increase) decrease in        
Accounts receivable and Contracts receivable  (114,080)  (449,458)
Income tax refundable  105,538   (33,924)
Prepaid expenses and other assets  (26,902)  (57,969)
Increase (decrease) in        
Accounts payable  1,372   57,940 
Accrued payroll and other expenses  28,798   30,209 
Accrued Bonus  60,000   (60,000)
Accrued income taxes  542,245   (88,683)
Deferred revenue  (9,409)  45,099 
Net cash provided by operating activities of continuing operations  4,472,847   3,234,948 
Net cash provided by (used in) operating activities of discontinued operations  (688,862)  262,595 
Net cash provided by operating activities  3,783,985   3,497,543 
         
Cash flows from investing activities        
Proceeds from sale of Words+, Inc.  1,973,096    
Proceeds from sale of assets  200   240 
Purchases of property and equipment  (106,835)  (19,101)
Purchase of royalty  (75,000)    
Capitalized computer software development costs  (958,507)  (797,319)
Net cash provided by (used in) investing activities of continuing operations  832,954   (816,180)
Net cash provided by (used in) investing activities of discontinued operations  6,532   (252,945)
Net cash provided by (used in) investing activities  839,486   (1,069,125)
         
Cash flows from financing activities        
Repurchase of common stock     (2,048,172)
Excess tax benefits from share-based arrangement  (22,091)  24,081 
Dividends  (2,382,994)   
Proceeds from the exercise of stock options  301,641   144,960 
Net cash (used in) financing activities of continuing operations  (2,103,444)  (1,879,131)
         
Net increase in cash and cash equivalents from continuing operations  3,202,357   539,637 
Net increase (decrease) in cash and cash equivalents from discontinued operations  (682,330)  9,650 
Net increase in cash and cash equivalents  2,520,027   549,287 
Cash and cash equivalents, beginning of year  10,181,049   9,631,762 
Cash and cash equivalents, end of period $12,701,076  $10,181,049 
         
Supplemental disclosures of cash flow information        
Interest paid $3  $43 
Income taxes paid $457,000  $320,232 

The accompanying notes are an integral part of these consolidated financial statements.

F-6

SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and 2011

 
F-6

SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010 and 2009


NOTE 1 - ORGANIZATION AND LINES OF BUSINESS


Organization

Simulations Plus, Inc. (the “Company”, “we”, “us”, “our”) was incorporated on July 17, 1996. On August 29, 1996, the shareholders of Words+, Inc. exchanged their 2,000 shares of Words+, Inc. common stock for 2,200,000 (Pre-split) shares of Simulations Plus, Inc. common stock, and Words+, Inc. became a wholly owned subsidiary of Simulations Plus, Inc. (collectively,The Words+ subsidiary was sold effective November 30, 2011, and is treated as “discontinued operations” in the "Company").


accompanying financial statements.

Lines of Business

The Company designs and develops pharmaceutical simulation software to promote cost-effective solutions to a number of problems in pharmaceutical research and in the education of pharmacy and medical students. The Company also developsdeveloped and sells interactive, educational software programs that simulate science experiments conducted in middle school, high school, and junior college science classes as well as a productivity software program called Abbreviate! that was moved from the Words+ subsidiary to Simulations Plus. In addition, the Company’s subsidiary designs and develops computer software and manufactures augmentative communication devices and computer access products that provide a voice for those who cannot speak and allow physically disabled persons to operate a standard computer.

NOTE 2 - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES


Use of Estimates

Our consolidated financial statements and accompanying notes are prepared in accordance with accounting principles generally accepted in the United States of America. Preparing financial statements requires management to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenue, and expenses. These estimates and assumptions are affected by management’s application of accounting policies. Actual results could differ from those estimates.


Principles of Consolidation

The consolidated financial statements of Simulations Plus, Inc. include the accounts of Simulations Plus, Inc. and itsWords+ up to November 30, 2011, the date of sale of the wholly owned subsidiary, Words+, Inc.subsidiary. All significant intercompany accounts and transactions arewere eliminated in consolidation.


The operations of Words+ are presented as “discontinued operations” in the financial statements.

Revenue Recognition

The Company recognizes

We recognize revenues related to software licenses and software maintenance in accordance with the Financial Accounting Standard Board (“FASB”) Accounting Standard Codification (“ASC”) 985-605.985-605, “Software - Revenue Recognition”. Software products revenue is recorded when the following conditions are met: 1) evidence of arrangement exists, 2) delivery has been made, 3) the amount is fixed, and 4) collectibilitycollectability is probable. Post-contract customer support ("PCS") obligations are insignificant; therefore, revenue for PCS is recognized at the same time as the licensing fee, and the costs of providing such support services are accrued and amortized over the obligation period.  For Words+ products, the revenue is recorded at the time of shipment, net of estimated allowances

F-7

SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and returns.


2011

 
F-7


SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010 and 2009


As a byproduct of ongoing improvements and upgrades for the new programs and new modules of software, some modifications are provided to customers who have already purchased software at no additional charge. Other software modifications result in new, additional cost modules that expand the functionality of the software. These are licensed separately. We consider the modifications that are provided without charge to be minimal, as they do not significantly change the basic functionality or utility of the software, but rather add convenience, such as being able to plot some additional variable on a graph in addition to the numerous variables that had been available before, or adding some additional calculations to supplement the information provided from running the software. Such software modifications for any single product have typically occurred once or twice per year, sometimes more, sometimes less. Thus, they are infrequent. The Company provides, for a fee, additional training and service calls to its customers and recognizes revenue at the time the training or service call is provided.


Generally, we enter into one-year license agreements with customers for the use of our pharmaceutical software products. We recognize revenue on these contracts when all the criteria are met.


Most license agreements have a term of one year; however, from time to time, we enter into multi-year license agreements. Weagreements.We generally unlock and invoice software one year at a time for multi-year licenses. Therefore, revenue is recognized one year at a time.

We recognize the revenue from collaboration research and the revenue from grants equally over their terms. However, we recognize the contract study revenue using the percentage of completion method, depending upon how the contract studies are engaged, in accordance with FASB ASC 605-35.605-35,Revenue Recognition – Construction-Type and Production-Type Contracts”. To recognize revenue using the percentage of completion method, we must determine whether we meet the following criteria:1) there is a long-term, legally enforceable contract and 2) it is possible to reasonably estimate the total project costs, and 3) it is possible to reasonably estimate the extent of progress toward completion.

Reclassifications

Certain numbers in the prior year have been reclassified to conform to the current year’s presentation.

Cash and Cash Equivalents

For purposes of the statements of cash flows, the Company considers all highly liquid investments purchased with original maturities of three months or less to be cash equivalents.


Accounts Receivable

The Company maintains an allowance for doubtful accounts for estimated losses that may arise if any of its customers are unable to make required payments.  Management specifically analyzes

We analyze the age of customer balances, historical bad debt experience, customer credit-worthiness,creditworthiness, and changes in customer payment terms when making estimates of the collectibilitycollectability of the Company’s trade accounts receivable balances. If the Company determineswe determine that the financial conditions of any of its customers deteriorated, whether due to customer-specific or general economic issues, an increase in the allowance may be made. Accounts receivable are written off when all collection attempts have failed. The Company also estimatesestimated the contractual discount obligation for third party funding suc hsuch as, Medicare, Medicaid, and private insurance companies. Those estimated discounts arewere reflected in the allowance for doubtful accounts and contractual discounts.discounts and included in discontinued operations. Although we experienced significant collection problems with our former Words+ subsidiary, we have not had customers fail to pay on the pharmaceutical software and services side of the business, which now represents our entire business after the sale of our former subsidiary on November 30, 2011.

F-8


SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and 2011

 
F-8


SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010 and 2009


Inventory
Inventory is stated at the lower of cost (first-in, first-out basis) or market and consists primarily of computers and peripheral computer equipment.

Capitalized Computer Software Development Costs

Software development costs are capitalized in accordance with FASB ASC 985-20.985-20,“Costs of Software to Be Sold, Leased, or Marketed”. Capitalization of software development costs begins upon the establishment of technological feasibility and is discontinued when the product is available for sale.


The establishment of technological feasibility and the ongoing assessment for recoverability of capitalized software development costs require considerable judgment by management with respect to certain external factors including, but not limited to, technological feasibility, anticipated future gross revenues, estimated economic life, and changes in software and hardware technologies. Capitalized computer software development costs are comprised primarily of salaries and direct payroll-related costs and the purchase of existing software to be used in the Company's software products.


Amortization of capitalized computer software development costs is provided on a product-by-product basis on the straight-line method over the estimated economic life of the products (not to exceed five years). Amortization of software development costs amounted to $644,014$668,021 and $519,415$660,893 for the years ended August 31, 20102012 and 2009,2011, respectively. We expect future amortization expense to vary due to increases in capitalized computer software development costs.


Management tests

We test capitalized computer software development costs for recoverability whenever events or changes in circumstances indicate that the carrying amount may not be recoverable.


Property and Equipment

Property and equipment are recorded at cost, less accumulated depreciation and amortization. Depreciation and amortization are provided using the straight-line method over the estimated useful lives as follows:


Equipment5 years
Computer equipment3 to 7 years
Furniture and fixtures5 to 7 years
Leasehold improvementsShorter of life of asset or lease


F-9


SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010 and 2009



Maintenance and minor replacements are charged to expense as incurred. Gains and losses on disposals are included in the results of operations.


Fair Value of Financial Instruments

AAssets and liabilities recorded at fair value in the Consolidated Balance Sheets are categorized based upon the level of judgment associated with the inputs used to measure their fair value. The categories, as defined by the standard, are as follows:

F-9

SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and 2011

Level Input: Input Definition:
Level I Inputs are unadjusted, quoted prices for identical assets or liabilities in active markets at the measurement date.
Level II Inputs, other than quoted prices included in Level I, that are observable for the asset or liability through corroboration with market data at the measurement date.
Level III Unobservable inputs that reflect management’s best estimate of what market participants would use in pricing the asset or liability at the measurement date.

The following table summarizes fair value measurements by level at August 31, 20102012 for assets and liabilities measured at fair value on a recurring basis:


  Level I  Level II  Level III  Total 
Cash and cash equivalents $9,631,762  $-  $-  $9,631,762 
                 
Total assets $9,631,762  $-  $   $9,631,762 

  Level I  Level II Level III Total 
Cash and cash equivalents $12,701,075  $ $ $12,701,075 
             
 Total assets $12,701,075  $ $ $12,701,075 

For certain of our financial instruments, including accounts receivable, accounts payable, accrued payroll and other expenses, accrued bonuses to officers, and accrued warranty and service costs, the carrying amounts are approximate fair value due to their short maturities.

Advertising

The Company expenses advertising costs as incurred. Advertising costs for the years ended August 31, 20102012 and 20092011 were $40,000$79,000 and $34,000,$37,000, respectively.


Shipping and Handling
Shipping and handling costs are recorded as cost of sales and amounted to $114,000 and $103,000 for the years ended August 31, 2010 and 2009, respectively.

Research and Development Costs

Research and development costs are charged to expense as incurred until technological feasibility has been established. These costs consist primarily ofinclude salaries, laboratory experiment, and direct payroll-related costs.  It also includes purchased software which was developed by other companies and incorporated into, or used in the development of, our final products.


Income Taxes

The Company utilizes FASBaccounts for income taxes in accordance with ASC 740-10,“Income Taxes” which requires the recognition of deferred tax assets and liabilities for the expected future tax consequences of events that have been included in the financial statements or tax returns.



F-10


SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010 and 2009


Under this method, deferred income taxes are recognized for the tax consequences in future years of differences between the tax bases of assets and liabilities and their financial reporting amounts at each year-end based on enacted tax laws and statutory tax rates applicable to the periods in which the differences are expected to affect taxable income. Valuation allowances are established, when necessary, to reduce deferred tax assets to the amount expected to be realized. The provision for income taxes represents the tax payable for the period and the change during the period in deferred tax assets and liabilities.

F-10

SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and 2011

The California Franchise Tax Board (“FTB”) audited us for the fiscal years ended (“FYE”) August 31, 2007 and 2008. We received refunds as we claimed; however they have now continued their audit to include FYE 2009 and 2010, and are reviewing 2007 and 2008 R&D credits since those credits were carried forward to FYE 2009 and 2010. In March 2012, we also received a notice from the Internal Revenue Service (IRS) that our fiscal year ended August 31, 2008 is subject to their examination. In October 2012, the IRS completed their examination of our 2007 tax filing. The outcome of this examination was a decrease of $36,868 in the amount refundable.

Intellectual property

On February 28, 2012, we bought out the royalty agreement with Enslein Research of Rochester, New York. The cost of $75,000 is being amortized over 10 years under the straight-line method. Amortization expense for the fiscal year ended August 31, 2012 was $3,750. Accumulated amortization as of August 31, 2012 was $3,750.

Customer relationships

We purchased customer relationships as a part of the acquisition of certain assets of Bioreason, Inc. in November 2005. Customer relationships was recorded at a cost of $128,042, and is being amortized over 78 months under the sum-of-the-years’-digits method. Amortization expense for the fiscal year ended August 31, 2012 and 2011 amounted to $1,871 and $7,730, respectively. Accumulated amortization as of August 31, 2012 and 2011 were $128,042 and $126,172, respectively.

Earnings per Share

The Company reports earnings per share in accordance with FASB ACS 260-10. Basic earnings per share is computed by dividing income available to common shareholders by the weighted-average number of common shares available. Diluted earnings per share is computed similarly to basic earnings per share except that the denominator is increased to include the number of additional common shares that would have been outstanding if the potential common shares had been issued and if the additional common shares were dilutive. The components of basic and diluted earnings per share for the years ended August 31, 20102012 and 20092011 were as follows:

  2012  2011 
Numerator      
Net income attributable to common shareholders $3,027,884  $2,714,641 
         
Denominator        
Weighted-average number of common shares outstanding during the year  15,921,196   15,540,047 
Dilutive effect of stock options  388,199   542,407 
         
Common stock and common stock equivalents used for diluted earnings per share  16,309,395   16,082,454 

F-11

SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and 2011


  2010  2009 
Numerator      
Net income attributable to common shareholders $2,156,073  $1,412,084 
         
Denominator        
Weighted-average number of common shares outstanding during the year  15,831,294   16,126,471 
Dilutive effect of stock options  681,724   1,061,076 
         
Common stock and common stock equivalents used for diluted earnings per share  16,513,018   17,187,547 

Stock-Based Compensation

The Company accounts for stock options using the modified prospective method in accordance with FASB ACS 718-10.718-10,“Compensation-Stock Compensation”. Under this method, compensation costs include: (1) compensation cost for all share-based payments granted prior to, but not yet vested as of September 1, 2006, based on the grant date fair value estimated in accordance with the original provisions of Statement of Financial Accounting Standard (“SFAS”) No. 123 amortized over the options’ vesting period, and (2) compensation cost for all share-based payments granted subsequent to September 1, 2006, based on the grant-date fair value estimated in accordance with the provisions of SFAS No. 123R, amortized on a straight-line basis over the options’ vesting period. Stock-based compensation was $127,597$181,520 and $183,294 f or$155,252 for the years ended August 31, 20102012 and 2009,2011, respectively, and is included in the consolidated statements of operations as Consulting, Salaries, and Research and Development expense.



F-11


SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010 and 2009



Concentrations and Uncertainties
Financial instruments that potentially subject the Company to concentration of credit risk consist principally of cash, cash equivalents and trade accounts receivable.  The Company holds cash and cash equivalents at banks located in California, with balances that often exceed FDIC insured limits.  Historically, the Company has not experienced any losses in such accounts and believes it is not exposed to any significant credit risk on cash and cash equivalents.  However, considering the current banking environment, the Company is investigating alternative ways to minimize its exposure to such risks.  While the Company may be exposed to credit losses due to the nonperformance of its counterparties, the Company does not expect the settlement of these transactions to have a ma terial effect on its results of operations, cash flows or financial condition.

International sales accounted for 34% and 32% of net sales for the years ended August 31, 2010 and 2009, respectively.  For Simulations Plus, Inc. (pharmaceutical segment), two customers accounted for 12% (one is a dealer account representing various customers) and 11% of net sales for the year ended August 31, 2010.  For the year ended August 31, 2009, two customers accounted for 13% each (one is a dealer account) of net sales.
For Words+, Inc., third-party billing, which includes various government agencies as well as private insurance companies, accounted for 65% and 50% of net sales for the years ended August 31, 2010 and 2009, respectively.  If changes are made in government funding policies for Words+ products, Words+ revenue may be impacted.  We continually evaluate and monitor regulatory developments in funding matters, and we do not expect Medicare and Medicaid of all 50 states to discontinue their funding of Words+ products; however, there can be no assurances that the current level of revenue from third parties will continue.

We operate in the computer software industry, which is highly competitive and changes rapidly.  Our operating results could be significantly affected by our ability to develop new products and find new distribution channels for new and existing products.

For Simulations Plus (pharmaceutical segment), one customer comprised 43% (a dealer account representing various customers) and 16% of accounts receivable at August 31, 2010, and two customers comprised 39% (one is a dealer account representing various customers) and 14% of accounts receivable at August 31, 2009.  For Words+, third-party billing, which includes various government agencies, comprised 84% of its accounts receivable at August 31, 2010 and 87% of its accounts receivable at August 31, 2009.  Collection of those accounts receivable in a timely manner is critical in Words+’ cash flow and its operations.  We have three dedicated funding/billing personnel who continually track such collections.

The Company’s subsidiary, Words+, Inc., purchases components for the main computer products from three manufacturers. Words+, Inc. also uses a number of pictographic symbols that are used in its software products which are licensed from a third party. The inability of the Company to obtain computers used in its products or to renew its licensing agreement to use pictographic symbols could negatively impact the Company's financial position, results of operations, and cash flows.

F-12


SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010 and 2009


Recently Issued Accounting Standards


In September 2009, the FASB issued ASU 2009-14 which amends Statement of Position (“SOP”) 97-2, “Software Revenue Recognition”, to exclude tangible products containing software components and non-software components that function together to deliver the product’s essential functionality. ASU 2009-14 applies to revenue arrangements entered into or materially modified in fiscal years beginning on or after June 15, 2010, with early application permitted with EITF 08-1. We expect to adoptadopted this standard in the first quarter of fiscal 2011. We are currently evaluatingbelieve adoption did not have a material effect on the impact ASU 2009-14 will have on our consolidatedCompany’s financial statements.


In September 2009, the FASB issued ASU 2009-13, “Revenue Arrangements with Multiple Deliverables” (“EITF 08-1”). ASU 2009-13 amends EITF 00-21, “Revenue Arrangements with Multiple Deliverables”, to require an entity to use an estimated selling price when vendor-specific objective evidence or acceptable third-party evidence does not exist for any products or services included in a multiple element arrangement. The arrangement consideration should be allocated among the products and services based upon their relative selling prices, thus eliminating the use of the residual method of allocation. ASU 2009-13 also requires expanded qualitative and quantitative disclosures regarding significant judgments made and changes in applying the guidance.  60;ASU 2009-13 applies to fiscal years beginning after June 15, 2010, with early application permitted. We expect to adoptadopted this standard in the first quarter of fiscal 2011. We are currently evaluatingbelieve adoption did not have a material effect on the impact ASU 2009-13 will have on our consolidatedCompany’s financial statements.

In May 2011, the Financial Accounting Standards Board (“FASB”) issued ASU 2011-04,Fair Value Measurement (“ASU 2011-04”), which amended ASC 820,Fair Value Measurements(“ASC 820”), providing a consistent definition and measurement of fair value, as well as similar disclosure requirements between U.S. GAAP and International Financial Reporting Standards. ASU 2011-04 changes certain fair value measurement principles, clarifies the application of existing fair value measurement and expands the disclosure requirements. We adopted this standard in the first quarter of 2012. We believe adoption did not have a material effect on the Company’s financial statements.

F-12

SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and 2011

In June 2011, the FASB issued ASU 2011-05,Presentation of Comprehensive Income (“ASU 2011-05”). ASU 2011-05 requires the presentation of comprehensive income in either (1) a continuous statement of comprehensive income or (2) two separate but consecutive statements. We adopted this standard in the first quarter of 2012. We believe adoption did not have a material effect on the Company’s financial statements.

In September 2011, the FASB issued ASU 2011-08,Testing Goodwill for Impairment (“ASU 2011-08”), which amends the guidance in ASC 350-20,Intangibles—Goodwill and Other – Goodwill. ASU 2011-08 provides entities with the option of performing a qualitative assessment before calculating the fair value of the reporting unit when testing goodwill for impairment. If the fair value of the reporting unit is determined, based on qualitative factors, to be more likely than not less than the carrying amount of the reporting unit, the entities are required to perform a two-step goodwill impairment test. We adopted this standard in the first quarter of 2012. We believe adoption did not have a material effect on the Company’s financial statements.

In December 2011, the FASB issued ASU No. 2011-11, "Disclosures about Offsetting Assets and Liabilities." The amendments in this update require enhanced disclosures around financial instruments and derivative instruments that are either (1) offset in accordance with either ASC 210-20-45 or ASC 815-10-45 or (2) subject to an enforceable master netting arrangement or similar agreement, irrespective of whether they are offset in accordance with either ASC 210-20-45 or ASC 815-10-45. An entity should provide the disclosures required by those amendments retrospectively for all comparative periods presented. The amendments are effective during interim and annual periods beginning after February 28, 2012. The Company does not expect this guidance to have any impact on its financial position, results of operations or cash flows.

NOTE 3 – PROPERTY AND EQUIPMENT


Property and equipment at August 31, 20102012 and 2009.2011 consisted of the following:


  2010  2009 
Automobile $21,769  $21,769 
Equipment  80,830   80,830 
Computer equipment  403,635   376,680 
Furniture and fixtures  61,498   61,498 
Leasehold improvements  53,898   53,898 
   621,630   594,675 
Less accumulated depreciation and Amortization  565,646   541,455 
         
Total $55,984  $53,220 

  2012  2011 
Equipment  123,062   39,374 
Computer equipment  272,562   255,074 
Furniture and fixtures  48,813   48,813 
Leasehold improvements  53,898   53,898 
   498,335   397,159 
Less accumulated depreciation and Amortization  390,925   354,149 
Total $107,410  $43,010 

Depreciation expense was $25,215$41,802 and $21,893$21,822 for the years ended August 31, 20102012 and 2009,2011, respectively.

F-13

SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and 2011

 
F-13


SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010 and 2009


NOTE 4 - COMMITMENTS AND CONTINGENCIES


Leases

We lease approximately 13,500 square feet of space under a five-year term with two (2), three (3)-year options to extend the lease. The base rent is $18,445 per month plus common area maintenance fees. The base rental rate increases at 4% annually. Rent expense, including common area maintenance fees, was $278,788 and $271,748$293,089 for the yearsyear ended August 31, 20102012 and 2009, respectively.$288,979, of which $144,490 was recorded as Simulations Plus rent expense and $144,489 was recorded as Words+ (a former subsidiary) rent expense for the year ended August 31, 2011. During the year ended August 31, 2010,2011, the Company exercised its option to extend the term of the lease to February 2, 2014.


After the sale of Words+, we entered into a month to month sublease agreement commencing January 1, 2012 under which Words+ pays 20 percent of the monthly rent we pay to our landlord, plus 20% of facility-related operating expenses. We report our gross lease expense under Selling, General and Administrative expense; however, the sublease payments received from Words+ are reported under Other Income.

Future minimum lease payments under non-cancelable operating leases with remaining terms of one year or more at August 31, 2012 were as follows:

Years Ending
August 31,
   
2013  286,601 
2014  121,362 
  $407,963 

On October 30, 2006, the Company entered into an equipment lease agreement. In this agreement, the Company leased a Ricoh Copier/Printer for 36 months with the option of earlier termination with a 60-day written notice. On October 30, 2009, we renewed the same agreement for another 36 months with an increment of 1 cent per copy on color printing which reflects their material cost.


Future minimum On April 17, 2012, we entered into a new lease paymentsagreement with ARC, a successor of former leasing company, for 36-month under non-cancelable operating leases with remaining terms of one year or more at August 31, 2010 werethe same term as follows:

Years Ending August 31,
  
2011 264,979
2012 275,578
2013 286,601
2014 121,362
 $948,520
the existing agreement.

Employment Agreement

On August 31, 2009,July 22, 2011, the Company entered into an employment agreement with its President/Chief Executive Officer that expires in August 2011.2013. The employment agreement provides for an annual base salary of $275,000$300,000 per year, and a performance bonus in an amount not to exceed 10% of Employee’s salary, or $27,500$30,000 per year, at the end of each fiscal year. The specific amount of the bonus to be awarded will be determined by the Compensation Committee of the Board of Directors, based on the financial performance and achievements of the Company for the previous fiscal year. The agreement also provides Employee stock options, exercisable for five years, to purchase fifty (50) shares of Common Stock for each one thousand dollars ($1,000) of net income before taxes at the end of each fisca lfiscal year up to a maximum of 120,000 options over the term of the agreement. The Company may terminate the agreement upon 30 days' written notice if termination is without cause. The Company's only obligation would be to pay its President the greater of a) 12 months salary or b) the remainder of the term of the employment agreement from the date of notice of termination.

F-14


SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and 2011

 
F-14


SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010

For fiscal year 2012, the Compensation Committee awarded a $30,000 performance bonus to Walter Woltosz, our President/Chief Executive Officer, and 2009



was paid in September 2012.

For fiscal year 2011, the Compensation Committee awarded a $27,500 performance bonus to Walter Woltosz. The bonus for FY2011, which was 100% of the previous year’s contract bonus amount, was paid in December 2011.

License Agreement

In 1997, the Company entered into an agreement with Therapeutic Systems Research Laboratory ("TSRL") to jointly develop a computer simulation software program of the absorption of drug compounds in the gastrointestinal tract. Upon execution of a definitive License Agreement on July 9, 1997, TSRL received an initial payment of $75,000, and thereafter, the Company is obligated to pay a royalty of 20% of the net sales of the basic GastroPlus software without additional modules.


In September 2007, the Companywe entered into an agreement with Enslein Research, Inc. (“Enslein”) to jointly create a new metabolism module as part of ADMET Predictor. The fee for the exclusive license to the Enslein Data, in the form of a royalty, is 50% of the gross sales revenues of the ADMET Predictor Enslein Metabolism Module, and a $50,000 bonus at the time the cumulative revenue from ADMET Predictor Enslein Metabolism Module sales reaches $250,000.


On February 28, 2012, we signed a buyout agreement with Enslein for $75,000, and are amortizing its cost over 10 years after this date.

We also have a royalty agreement with Accelrys (the original agreement with Symyx in March 2010) for Metabolite Database access for developing our Metabolite module which was renamed as Metabolism module when we released ADMET Predictor version 6 on April 19, 2012. Under this agreement, we pay 25% of revenue derived from the sale of Metabolism/Metabolite module.

For the years ended August 31, 20102012 and 2009, Simulations Plus, Inc.2011, we incurred total royalties of approximately $441,000$601,000 and $413,000,$575,000, respectively.


The Company’s subsidiary, Words+, Inc., entered into royalty agreements with several vendors to apply their software & technologies into the finished goods to be sold.  For the years ended August 31, 2010 and 2009, Words+ incurred royalties of approximately $26,000 and $32,000, respectively.

Legal Matters


We are not a party to any litigation at this time and we are not aware of any pending litigation of any kind.


NOTE 5 - SHAREHOLDERS' EQUITY


Stock Repurchase
On October 23, 2008, the

Dividend

The Board of Directors authorized a share repurchase program (Phase I) enablingdeclared cash dividend during fiscal year 2012. The details of dividend paid are in the buyback of up to $2.5 million in shares during a 12-month period beginning Monday, October 27, 2008.  The actual repurchase started on December 2, 2008; therefore the Board of Directors extended it through December 1, 2009 in order to have a full 12-month period.  We opened an account with Morgan Stanley Smith Barney for the purchase of such securities. Funds for any stock purchases are drawn from our cash reserves.following table:

F-15

SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and 2011

Record Date Distribution Date Number of Shares Outstanding on Record Date  Dividend per Share Total Amount 
02/21/2012 03/01/2012  15,813,844  $0.05 $790,692.20 
04/27/2012 05/08/2012  15,923.019  $0.05 $796,150.95 
08/07/2012 08/10/2012  15,923.019  $0.05 $796,150.95 
Total         $2,382,994.10 

Stock Repurchase

On January 10, 2010, the Board of Directors authorized a renewed share repurchase program (Phase II) effective as of February 15, 2010. The renewed program enablesenabled the Company to buy back up to one million shares during a 12-month period.


The details of repurchases made during the years ended August 31, 2010 and 2009under Phase II are listed in the following table:



F-15


SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010 and 2009


Period
Total Number of
Shares Purchased
Average Price
Paid per Share
Remaining Funds
Available Under the
Share Repurchase Plan
(including broker’s fees)
12/02/08 to 12/31/0890,632 $0.9764 $2,409,631 
01/01/09 to 01/31/09105,752 $1.0352 $2,296,807 
02/01/09 to 02/28/0973,118 $1.0086 $2,221,124 
03/01/09 to 03/31/09 73,315 $0.9575 $2,149,168 
04/01/09 to 04/30/09 55,580 $1.0045 $2,091,896 
05/01/09 to 05/31/09 44,083 $1.1360 $2,041,649 
06/01/09 to 06/30/09171,740*$1.3885 $1,799,550 
07/01/09 to 07/31/09131,308 $1.5321 $1,596,486 
08/01/09 to 08/31/09101,314 $1.7467 $1,416,478 
09/01/09 to 09/30/0982,630 $1.6989 $1,274,155 
10/01/09 to 10/31/0952,364 $1.5685 $1,190,386 
11/01/09 to 11/30/0942,061 $1.4884 $1,126,560 
12/01/092,586 $1.3823 $1,122,985 
 
Phase I Total
1,026,483 $1.3823   

Period
Total Number of
Shares Purchased
Average Price
Paid per Share
Remaining Shares
Authorized for
Repurchase Under the
Share Repurchase
Plan – Phase II
04/01/10 to 04/30/1086,976 $2.2237 913,024 
05/01/10 to 05/31/10170,101 $2.3515 742,923 
06/01/10 to 06/30/1033,665 $2.3670 709,258 
07/01/10 to 07/31/1018,789 $2.4433 690,469 
08/01/10 to 08/31/1010,878 $2.4283 679,591 
 
Phase II Total
320,409 $2.3264   

Period Total Number of Shares Purchased  Average Price Paid per Share  Remaining Shares Authorized for Repurchase Under the Share Repurchase Plan – Phase II 
04/01/10 to 04/30/10  86,976  $2.2237   913,024 
05/01/10 to 05/31/10  170,101  $2.3515   742,923 
06/01/10 to 06/30/10  33,665  $2.3670   709,258 
07/01/10 to 07/31/10  18,789  $2.4433   690,469 
08/01/10 to 08/31/10  10,878  $2.4283   679,591 
09/01/10 to 09/30/10  81,070  $2.6969   598,521 
10/01/10 to 10/31/10  170,494  $3.1671   428,027 
11/01/10 to 11/30/10  146,116  $2.9523   281,911 
12/01/10 to 12/31/10  41,214  $2.5716   240,697 
01/01/11 to 01/31/11  119,469  $2.9028   121,228 
02/01/11 to 02/28/11  117,476  $3.4510   3,752 
Phase II Total  996,248  $2.8041     

*Phase II repurchase program ended on 02/14/2011.

Stock Option Plan

In September 1996, the Board of Directors adopted, and the shareholders approved, the 1996 Stock Option Plan (the "Option Plan") under which a total of 1,000,000 shares of common stock had been reserved for issuance. In March 1999, the shareholders approved an increase in the number of shares that may be granted under the Option Plan to 2,000,000. In February 2000, the shareholders approved an increase in the number of shares that may be granted under the Option Plan to 4,000,000. In December 2000, the shareholders approved an increase in the number of shares that may be granted under the Option Plan to 5,000,000. Furthermore, in February 2005, the shareholders approved an additional 1,000,000 shares, resulting in the total number of shares that may be granted under the Opt ionOption Plan to 6,000,000. The 1996 Stock Option Plan terminated in September 2006 by its term.

F-16


SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and 2011

 
F-16


SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010 and 2009


On February 23, 2007, the Board of Directors adopted and the shareholders approved the 2007 Stock Option Plan under which a total of 1,000,000 shares of common stock had been reserved for issuance.


The number of shares described above are adjusted reflecting the two-for-one stock splits on August 14, 2006 and October 1, 2007.

The following table summarizes the stock option transactions.


TRANSACTIONS IN FY 20102012 AND 20092011

Transactions in FY11
(Incentive Stock Option Plan)
 Number of Options  

Weighted-Average Exercise Price

Per Share

  Weighted-Average Remaining Contractual Life 
          
Outstanding, August 31, 2010  1,493,902  $1.13     
Granted  20,000  $3.27     
Exercised  (442,300) $0.54     
Canceled/Forfeited  (107,066) $1.61     
Expired  (6,900) $0.88     
             
Outstanding, August 31, 2011  957,636  $1.40   5.22 
Vested and Exercisable, August 31, 2011  687,102  $1.27   4.522 
Vested and Expected to Vest, August 31, 2011  931,883  $1.37   5.132 

Transactions in FY12
(Incentive Stock Option Plan)
 Number of Options  Weighted-Average Exercise Price
Per Share
  Weighted-Average Remaining Contractual Life 
          
Outstanding, August 31, 2011  957,636  $1.40    
Granted  100,000  $3.25    
Exercised  (360,736) $1.22    
Expired  (7,100) $2.54    
             
Outstanding, August 31, 2012  689,800  $1.74   4.523 
Vested and Exercisable, August 31, 2012  467,100  $1.42   4.071 
Vested and Expected to Vest, August 31, 2012  666,789  $1.71   4.451 

F-17
 
 
Transactions in FY09
 
Number of Options
  
Weighted-Average Exercise Price
Per Share
  
Weighted-Average Remaining Contractual Life
 
          
Outstanding, August 31, 2008  2,714,536  $0.91    
Granted  392,000  $1.09    
Exercised  (237,000) $0.51    
Canceled/Forfeited  (3,000) $3.02    
Expired  (4,000) $0.38    
            
Outstanding, August 31, 2009  2,862,536  $0.97   3.927 
Exercisable, August 31, 2009  2,158,136  $0.74   2.346 

SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and 2011

 
 
 
Transactions in FY10
 
Number of Options
  
Weighted-Average Exercise Price
Per Share
  
Weighted-Average Remaining Contractual Life
 
          
Outstanding, August 31, 2009  2,862,536  $0.97    
Granted  252,666  $1.79    
Exercised  (931,800) $0.60    
Canceled/Forfeited  (41,000) $1.39    
Expired  (648,500) $1.44    
            
Outstanding, August 31, 2010  1,493,902  $1.13   4.248 
Exercisable, August 31, 2010  934,036  $0.87   3.245 

The fair value of the options, including options to outside board members, granted during the year ended August 31, 20102012 is estimated at $225,650.$167,124. The fair value of these options was estimated at the date of grant using the Black-Scholes option-pricing model with the following assumptions for the fiscal year ended August 31, 2010:2012: dividend yield of 0.41%, pre-vest forfeiture rate of 5.61% to 6.09%, expected volatility of 62.27% to 69.87%, risk-free interest rate of 0.82% to 1.01%, and expected life of 5.0 years to 7.0 years. The total fair value of non-vested stock options as of August 31, 2012 was $292,426 and is amortizable over a weighted average period of 2.03 years.

During the previous fiscal year ended August 31, 2011, the fair value of the options granted is estimated at $57,384. The assumptions were dividend yield of 0%, pre-vest forfeiture rate of 2.32% to 40.71%, expected volatility of 54.71% to 79.91%, risk-free interest rate of 0.43%1.42% to 2.35%2.66%, and expected life of 1.0 to 5.04.0 years. The total fair value of non-vested stock options as of August 31, 20102011 was $509,478$270,387 and is amortizable over a weighted average period of 2.822.18 years.



F-17


SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010 and 2009


During the previous fiscal year ended August 31, 2009, the fair value of the options granted is estimated at $307,571.  The assumptions were dividend yield of 0%, expected volatility of 67.78% to 81.34%, risk-free interest rate of 2.67% to 3.17%, and expected life of 7 to 7.7 years.

During the years ended August 31, 2010 and 2009,, the Company recognized an income tax benefit of $1,130,577 and $0, respectively, relating to stock-based compensation arrangements.

The Black-Scholes option valuation model was developed for use in estimating the fair value of traded options, which do not have vesting restrictions and are fully transferable. In addition, option valuation models require the input of highly subjective assumptions, including the expected stock price volatility. Because the Company'sour employee stock options have characteristics significantly different from those of traded options, and because changes in the subjective input assumptions can materially affect the fair value estimate, in management's opinion, the existing models do not necessarily provide a reliable single measure of the fair value of its employee stock options.


The weighted-average remaining contractual life of options outstanding issued under the Plan was 4.24.17 years at August 31, 2010.2012. The exercise prices for the options outstanding at August 31, 20102012 ranged from $0.26$1.00 to $3.02,$6.68, and the information relating to these options is as follows:

Exercise Price Awards Outstanding Awards Exercisable
Low High Quantity  Weighted Average Remaining Contractual Life Weighted Average Exercise Price Quantity  Weighted Average Remaining Contractual Life Weighted Average Exercise Price
$1.00 $1.50  382,700  4.8 years $1.07  311,900  4.4 years $1.08
$1.51 $3.00  154,600  4.1 years $1.88  199,800  3.1 years $1.73
$3.01 $4.50  185,100  5.0 years $3.26  48,400   5.3 years $3.08
$4.51 $6.68  4,000  5.0 years $6.68  4,000   5.0 years $6.68
     726,400       484,100     

F-18

SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and 2011

Exercise Price  Awards Outstanding  Awards Exercisable 
Low  High  Quantity Weighted Average Remaining Contractual Life Weighted Average Exercise Price  Quantity Weighted Average Remaining Contractual Life Weighted Average Exercise Price 
$0.26  $0.75   392,236 0.6 years $0.36   392,236 0.6 years $0.36 
$0.76  $1.25   725,000 5.9 years $1.08   502,200 5.0 years $1.13 
$1.26  $3.02   376,666 4.9 years $2.03   39,600   7.6 years $2.69 
         1,493,902        934,036      
 

Intrinsic Value of options outstanding and options exercisable


  Intrinsic Value of Options Outstanding  Intrinsic Value of Options Exercisable  Intrinsic Value of Options Exercised 
FY10 $2,029,935  $1,499,527  $931,631 
FY09 $2,713,395  $2,354,206  $191,400 

F-18


SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010 and 2009



   Intrinsic Value of Options Outstanding  Intrinsic Value of Options Exercisable  Intrinsic Value of Options Exercised 
 FY11  $1,755,674  $1,348,809  $1,092,176 
 FY12  $1,918,904  $1,447,900  $982,786 

Other Stock Options

As of August 31, 2010,2012, the outside members of the Board of Directors holdshold options to purchase 71,00079,000 shares of common stock at exercise prices ranging from $0.30$0.38 to $6.68.


 
Transactions in FY09
 
Number of Options
  
Weighted-Average Exercise Price
Per Share
 
       
Outstanding, August 31, 2009  51,000  $1.89 
Granted  24,000  $2.06 
Exercised  (4,000) $0.63 
         
Outstanding, August 31, 2010  71,000  $2.02 
Exercisable, August 31, 2010  46,850  $1.99 


Transactions in FY11 Number of Options  

Weighted-Average Exercise Price

Per Share

 
       
Outstanding, August 31, 2010  71,000  $2.02 
Granted  12,000     
Exercised  (4,000)    
         
Outstanding, August 31, 2011  79,000  $2.29 
Exercisable, August 31, 2011  50,950  $2.15 

Transactions in FY12 Number of Options  

Weighted-Average Exercise Price

Per Share

 
       
Outstanding, August 31, 2011  79,000  $2.29 
Granted  10,000  $4.46 
Exercised  (40,800) $1.25 
Canceled/Forfeited  (11,600) $4.10 
         
Outstanding, August 31, 2012  36,600  $3.47 
Exercisable, August 31, 2012  17,000  $3.35 

NOTE 6 - INCOME TAXES


The components of the income tax provision for the years ended August 31, 20102012 and 20092011 were as follows:

  2012  2011 
Current      
Federal $(872,907) $(623,006)
State  (177,975)  (148,171)
   (1,050,882)  (771,177)
Deferred        
Federal  114,712   (262,536)
State  (22,901)  (21,560)
   91,811   (284,096)
         
Total $(1,142,693) $(1,055,273)

F-19

SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and 2011

 
  2010  2009 
Current      
Federal $(531,586) $(491,258)
State  (127,014)  (90,690)
   (658,600)  (581,948)
Deferred        
Federal  (260,843)  (14,912)
State  (28,986)  (17,716)
   (289,829)  (32,628)
         
Total $(948,429) $(614,576)

A reconciliation of the expected income tax (benefit) computed using the federal statutory income tax rate to the Company's effective income tax rate is as follows for the years ended August 31, 20102012 and 2009:

  2010  2009 
Income tax computed at federal statutory tax rate  34.0%   34.0% 
State taxes, net of federal benefit  2.7   6.1 
Meals & Entertainment  0.2   0.6 
Other permanent differences  (1.5)  (1.8)
Research and development credit  (5.1)  (9.4)
Change in prior year estimated taxes  0.3   0.8 
         
Total  30.6%   30.3% 
F-19


SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010 and 2009


2011:

  2012  2011 
Income tax computed at federal statutory tax rate  34.0%   34.0% 
State taxes, net of federal benefit  3.3   2.6 
Meals & Entertainment  0.1   0.1 
Other permanent differences  0.8   (1.0)
Research and development credit  (8.4)  (8.2)
Change in prior year estimated taxes  (0.9)  0.5 
Total  28.9%   28.0% 

Significant components of the Company's deferred tax assets and liabilities for income taxes for the years ended August 31, 20102012 and 20092011 are as follows:

  2012  2011 
Deferred tax assets        
Accrued payroll and other expenses $79,922  $91,489 
Accrued warranty and service costs     18,732 
Bad debt allowance     99,982 
Deferred revenue  56,456   60,486 
Property and equipment  32,916   60,626 
Research and development credit  261,526   289,357 
State taxes  66,902   50,378 
         
Total deferred tax assets  497,722   671,050 
Less:  Valuation allowance      
   497,722   671,050 
Deferred tax liabilities        
State Tax Deferred  (30,663)  (26,710)
Capitalized computer software development costs  (1,062,204)  (1,031,869)
         
Total deferred tax liabilities  (1,092,867)  (1,058,579)
         
Net deferred tax liabilities $(595,145) $(387,529)

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SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and 2011

  2010  2009 
Deferred tax assets      
Accrued payroll and other expenses $108,488  $90,795 
Accrued warranty and service costs  15,245   18,522 
Bad debt allowance  180,407   191,525 
Deferred revenue  41,166   27,945 
Property and equipment  33,856   - 
Research and development credit  525,650   - 
State taxes  43,185   69,723 
         
Total deferred tax assets  947,997   398,510 
Less:  Valuation allowance  -   - 
   947,997   398,510 
Deferred tax liabilities        
Property and equipment  -   (22,799)
State Tax Deferred  (53,481)  - 
Capitalized computer software development costs  (940,775)  (832,335)
         
Total deferred tax liabilities  (994,256)  (855,135)
         
Net deferred tax assets or (liabilities) $(46,259) $(456,624)

The Company follows

We follow guidance issued by the FASB with regard to its accounting for uncertainty in income taxes recognized in the financial statements. Such guidance prescribes a recognition threshold of more likely than not and a measurement process for financial statement recognition and measurement of a tax position taken or expected to be taken in a tax return. In making this assessment, a company must determine whether it is more likely than not that a tax position will be sustained upon examination, based solely on the technical merits of the position and must assume that the tax position will be examined by taxing authorities. Our policy is to include interest and penalties related to unrecognized tax benefits in income tax expense. Interest and penalties totaled $7,191$1,300 and $1,028$1,035 for the y earsyears ended August 31, 20102012 and 2009,2011, respectively. The Company filesWe file income tax returns with the Internal Revenue Service (“IRS”) and the state of California. For jurisdictions in which tax filings are prepared, the Company iswe are no longer subject to income tax examinations by state tax authorities for years through 2004,2006, and by the IRS for years through 2005.2007. As of August 31, 2010,2012, the Company’s tax returns for tax year ends August 31, 20072009 and 20082010 are under examination by the California Franchise Tax Board. The potential outcome of these examinations cannot be determined as of August 31, 2012. As of August 31, 2012, our 2007 tax filing was also under examination by the IRS. In October 2012, the IRS completed their examination of our 2007 tax filing, the result of which was a decrease of $36,868 in the amount refundable. Our review of prior year tax positions using the criteria and provisions presented in guidance issued by FASB did not resultresultin in a material impact on the Company’s financial position or results of operations.


F-20


SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010 and 2009


NOTE 7 - LINES OF BUSINESS


For internal reporting purposes, management segregates– CONCENTRATIONS AND UNCERTAINTIES

Financial instruments that potentially subject the Company into two divisions.to concentration of credit risk consist principally of cash, cash equivalents and trade accounts receivable. The segment informationCompany holds cash and cash equivalents at banks located in California, with balances that often exceed FDIC insured limits. Historically, the Company has not experienced any losses in such accounts and believes it is as followsnot exposed to any significant credit risk on cash and cash equivalents. However, considering the current banking environment, the Company is investigating alternative ways to minimize its exposure to such risks. While the Company may be exposed to credit losses due to the nonperformance of its counterparties, the Company does not expect the settlement of these transactions to have a material effect on its results of operations, cash flows or financial condition.

Revenue concentration shows that International sales accounted for 49% and 36% of net sales for the years ended August 31, 20102012 and 2009:2011, respectively. Two customers accounted for 10% (one is a dealer account representing various customers) and 6% of net sales for the year ended August 31, 2012. For the year ended August 31, 2011, three customers accounted for 11% (one is a dealer account representing various customers), 8% and 7% of net sales.

Accounts receivable concentration shows that two customers comprised 28% (a dealer account representing various customers) and 22% of accounts receivable at August 31, 2012, and two customers comprised 36% (a dealer account representing various customers) and 18% of accounts receivable at August 31, 2011.

F-21
  August 31, 2010 
  Simulations          
  Plus, Inc.  Words+, Inc.  Eliminations  Total 
             
Net sales $7,620,748  $3,091,081  $-  $10,711,829 
Income from operations $2,955,389  $(84,761) $-  $2,870,628 
Identifiable assets $14,434,920  $1,673,227  $(1,447,702) $14,660,445 
Capital expenditures $39,013  $12,519  $-  $51,532 
Depreciation/Amortization $628,677  $54,266  $-  $682,943 
Stock-based compensation $97,494  $30,103  $-  $127,597 
Interest Income $101,369  $176  $-  $101,545 
Income tax expense $948,429  $-  $-  $948,429 

  August 31, 2009 
  Simulations          
  Plus, Inc.  Words+, Inc.  Eliminations  Total 
             
Net sales $6,301,355  $2,841,916  $-  $9,143,271 
Income from operations $1,899,260  $(87,431) $-  $1,811,829 
Identifiable assets $11,937,864   $1,966,042  $(1,636,900) $12,267,006 
Capital expenditures $23,106  $21,454  $-  $44,560 
Depreciation/Amortization $508,629  $52,378  $-  $561,007 
Stock-based compensation $157,169  $26,125  $-  $183,294 
Interest Income $93,769  $105  $-  $93,874 
Income tax expense $614,576  $-  $-  $614,576 

Most corporate expenses, such as legal

SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and accounting expenses, public relations expenses, and bonuses to the President and Secretary are included in Simulations Plus, Inc.



2011

 
F-21


SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010

We operate in the computer software industry, which is highly competitive and 2009



changes rapidly. Our operating results could be significantly affected by our ability to develop new products and find new distribution channels for new and existing products.

The majority of our customers are in the pharmaceutical industry. During the current economy downturn, we have seen consolidation in the pharmaceutical industry. Although we have not seen any significant reduction in revenues to date, continued consolidation and downsizing in the pharmaceutical industry could have an impact on our revenues and earnings going forward.

NOTE 8 - GEOGRAPHIC REPORTING


Prior to the sale of Words+ on November 30, 2011, the Company operated in two business segments, which consisted of the pharmaceutical software and consulting services business and the augmentative communication devise business. Upon the sale of Words+ on November 30, 2011, the Company ceased operations in the augmentative communication devise business. The results of this segment are presented as discontinued operations in the accompanying financial statements. The pharmaceutical software segment, which represents the Company’s ongoing business, is presented as continuing operations.

The Company allocates revenues to geographic areas based on the locations of its customers. Geographical revenues were as follows for the fiscal years ended August 31, 20102012 and 2009:2011:

   August 31, 2012 
 
(in ‘000)
  North America   

 

Europe

   

 

Asia

   South America   

 

Total

 
 
Simulations Plus, Inc.
  4,805   2,986   1,633   25   9,449 

   August 31, 2011 
 
(in ‘000)
  North America   

 

Europe

   

 

Asia

   South America   

 

Total

 
 
Simulations Plus, Inc.
  4,548   2,606   1,554   31   8,739 

NOTE 9 – RELATED PARTY TRANSACTIONS

As of August 31, 2012, included in bonus expenses to officers was $87,500, of which $60,000 was accrued bonus representing 5% of the Company’s FY12 net income before bonuses and taxes, not exceeding $60,000, paid to the Corporate Secretary, Virginia Woltosz, as an annual bonus as part of the terms of the sale of Words+ to Simulations Plus in 1996. The other $27,500, paid in December 2011, was FY2011 performance bonus to Walter Woltosz, our President/Chief Executive Officer.

F-22

SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and 2011

  August 31, 2010 
 
(in ‘000)
 North America  Europe  Asia  Oceania  South America  Total 
 
Simulations Plus, Inc.
  4,132   2,240   1,238   -   11   7,621 
 
Words+, Inc.
  2,960   27   44   60   0   3,091 
 
Total
  7,092   2,267   1,282   60   11   10,712 


  August 31, 2009 
 
(in ‘000)
 North America  Europe  Asia  Oceania  South America  Total 
 
Simulations Plus, Inc.
  3,505   1,822   974   -   -   6,301 
 
Words+, Inc.
  2,723   50   17   50   2   2,842 
 
Total
  6,228   1,872   991   50   2   9,143 
 

NOTE 910 – CUSTOMER RELATIONSHIPS


The Company purchased customer relationships as a part of the acquisition of certain assets of Bioreason, Inc. in November 2005. Customer relationships was recorded at a cost of $128,042 and is being amortized over 78 months under the sum-of-the-years’-digits method. Amortization expense for the years ended August 31, 20102012 and 20092011 amounted to $13,714$1,871 and $19,699,$7,730, respectively. Accumulated amortization was $118,442$128,042 as of August 31, 2010.



F-22


SIMULATIONS PLUS, INC. AND SUBSIDIARY
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
August 31, 2010 and 2009


2012.

NOTE 1011 - EMPLOYEE BENEFIT PLAN


We maintain a 401(k) Plan for all eligible employees. We make matching contributions equal to 100% of the employee’s elective deferral, not to exceed 4% of the total employee compensation. We can also elect to make a profit-sharing contribution. Contributions by the Company to this Plan amounted to $84,949$89,258 and $79,787$81,074 for the years ended August 31, 20102012 and 2009,2011, respectively.

NOTE 12 - DISCONTINUED OPERATIONS

On November 30, 2011, we sold our interest in Words+, Inc. for $1,973,096 in cash. Words+ operations are now presented as discontinued operations in accordance with accounting rules related to the disposal of long-lived assets.

We recognized a gain of $465,820, net of tax, from this sale, which is included in income from discontinued operations in our statement of operations for the fiscal quarter ended November 30, 2011. The revenue and expenses of discontinued operations for the first fiscal quarter of 2012 and the fiscal year ended August 31, 2011 are as follows:

(in thousands) Period
from 09/01/11
to 11/30/11
  For the fiscal year ended 08/31/11 
Net sales $479  $2,981 
Cost of sales  265   1,381 
Gross profit  214   1,600 
Selling, general and administrative  563   1,466 
Research and development  55   64 
Total operating expenses  618   1,530 
Income (Loss) from discontinued operations  (404)  70 
Other income     2 
Income (Loss) from discontinued operations before income taxes  (404)  72 
(Provision for) income taxes  154   20 
Results from discontinued operations, net of tax $(250) $52 

F-23

SIMULATIONS PLUS, INC.

NOTES TO FINANCIAL STATEMENTS

August 31, 2012 and 2011

The carrying amount of the assets and liabilities of discontinued operations at August 31, 2011 and just prior to the date of the sale on November 30, 2011 were as follows:

(in thousands) 11/30/11  08/31/11 
Cash and cash equivalents $6  $143 
Receivables, net  357   603 
Inventory  392   392 
Prepaid and other current assets  33   57 
Capitalized software development costs, net  212   220 
Property and equipment, net  91   120 
    Total Assets  1,091   1,535 
         
Accounts payable  72   116 
Accrued payroll and other expenses  109   219 
Accrued warranty and service costs  37   44 
Total Liabilities  218   379 
         
Net Assets of discontinued operations $873  $1,156 

NOTE 1113 - SUBSEQUENT EVENTS


On October 26, 2012, our board of directors declared the next quarterly cash dividend of $0.05 per share to our shareholders. The detailsdividend will be distributed on Wednesday, November 13, 2012, for shareholders of repurchases made since August 31, 2010 are listed in the following table.  Thus, adding these shares to those described above through August 31, 2010, the total numberrecord as of shares repurchased throughFriday, November 19, 2010 under the phase II was 718,089.

8, 2012.

F-20


Period
Total Number of
Shares Purchased
Average Price
Paid per Share
Remaining Shares
Authorized for
Repurchase Under the
Share Repurchase
Plan – Phase II
09/01/10 to 09/30/1081,070 $2.6969 598,521 
10/01/10 to 10/31/10170,494 $3.1671 428,027 
11/01/10 to 11/19/10146,116 $2.9523 281,911 
 
As of 11/19/10
397,680 $2.9923   

From September 1, 2010 to November 19, 2010, an additional 66,653 stock options to purchase shares have been exercised by employees that generated $13,325 in cash.

The Company noticed that there was ambiguity between the 2007 Stock Option Plan and the compensation in the employment agreement with Walter Woltosz, CEO of the Company. In compliance with the 2007 Stock Option Plan, he agreed to return 102,666 stock options to the Company.

 
 F-23