UNITED STATES

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549

FORM 10-Q

☒ Quarterly report pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

For the quarterly period ended ~~March 31,~~June 30, 2023

☐ Transition report pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

For the transition period from to

Commission file number 001-33957

HARVARD BIOSCIENCE, INC.

(Exact Name of Registrant as Specified in Its Charter)

Delaware	04-3306140
(State or other jurisdiction of Incorporation or organization)	(I.R.S. Employer Identification No.)

84 October Hill Road, Holliston, Massachusetts 01746

(Address of Principal Executive Offices, including zip code)

(508) 893-8999

(Registrant’s telephone number, including area code)

Securities registered pursuant to Section 12(b) of the Act:

Title of each class	Trading Symbol(s)	Name of each exchange on which registered
Common Stock, $0.01 par value	HBIO	The Nasdaq Global Market

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes ☒ No ☐

Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S- T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). Yes ☒ No ☐

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

Large accelerated filer ☐	Accelerated filer ☒
Non-accelerated filer ☐	Smaller reporting company ☒
	Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes ☐ No ☒

As of ~~April 20,~~July 31, 2023, there were ~~42,190,043~~42,688,246 shares of the registrant’s common stock issued and outstanding.

Table of Contents

	March 31,			December 31,
	2023			2022			June 30, 2023			December 31, 2022
Assets
Current assets:
Cash and cash equivalents	$	3,789		$	4,508		$	4,324		$	4,508
Accounts receivable, net		17,737			16,705			16,903			16,705
Inventories		26,861			26,439			26,089			26,439
Other current assets		4,062			3,472			5,301			3,472
Total current assets		52,449			51,124			52,617			51,124
Property, plant and equipment, net		3,424			3,366			3,491			3,366
Operating lease right-of-use assets		5,505			5,816			5,253			5,816
Goodwill		56,618			56,260			56,771			56,260
Intangible assets, net		19,641			21,014			18,356			21,014
Other long-term assets		7,941			7,780			6,411			7,780
Total assets	$	145,578		$	145,360		$	142,899		$	145,360
Liabilities and Stockholders' Equity
Current liabilities:
Current portion of long-term debt	$	2,970		$	3,811		$	3,220		$	3,811
Current portion of operating lease liabilities		2,130			2,135			2,125			2,135
Accounts payable		5,978			6,447			4,716			6,447
Deferred revenue		4,121			3,370			3,835			3,370
Other current liabilities		8,018			7,486			9,046			7,486
Total current liabilities		23,217			23,249			22,942			23,249
Long-term debt, net		41,083			43,013			38,203			43,013
Deferred tax liability		546			590			667			590
Operating lease liabilities		4,938			5,282			4,653			5,282
Other long-term liabilities		1,454			1,006			1,046			1,006
Total liabilities		71,238			73,140			67,511			73,140
Commitments and contingencies - Note 13
Stockholders' equity:
Preferred stock, par value $0.01 per share, 5,000,000 shares authorized		-			-			-			-
Common stock, par value $0.01 per share, 80,000,000 shares authorized: 42,190,043 shares issued and outstanding at March 31, 2023; 42,081,707 shares issued and outstanding at December 31, 2022		455			454
Common stock, par value $0.01 per share, 80,000,000 shares authorized: 42,688,246 shares issued and outstanding at June 30, 2023; 42,081,707 shares issued and outstanding at December 31, 2022								457			454
Additional paid-in-capital		230,108			229,008			231,533			229,008
Accumulated deficit		(141,568	)		(142,190	)		(142,548	)		(142,190	)
Accumulated other comprehensive loss		(14,655	)		(15,052	)		(14,054	)		(15,052	)
Total stockholders' equity		74,340			72,220			75,388			72,220
Total liabilities and stockholders' equity	$	145,578		$	145,360		$	142,899		$	145,360

												Accumulated																	Accumulated
Three Months Ended																		*Number*					*Additional*						*Other*			*Total*
June 30, 2023																		*of Shares*			*Common*		*Paid-in*			*Accumulated*			*Comprehensive*			*Stockholders*’
	*Number*					*Additional*						*Other*			*Total*			*Issued*			*Stock*		*Capital*			*Deficit*			*Loss*			*Equity*
	*of Shares*			*Common*		*Paid-in*			*Accumulated*			*Comprehensive*			*Stockholders*’
	*Issued*			*Stock*		*Capital*			*Deficit*			*Loss*			*Equity*
Balance at December 31, 2022		42,082		$	454	$	229,008		$	(142,190	)	$	(15,052	)	$	72,220
Balance at March 31, 2023																			42,190		$	455	$	230,108		$	(141,568	)	$	(14,655	)	$	74,340
Stock option exercises		39			1		103			-			-			104			173			2		403			-			-			405
Vesting of restricted stock units		125			-		-			-			-			-
Shares withheld for taxes		(56	)		-		(156	)		-			-			(156	)
Stock-based compensation expense		-			-		1,153			-			-			1,153
Net income		-			-		-			622			-			622
Other comprehensive income		-			-		-			-			397			397
Balance at March 31, 2023		42,190		$	455	$	230,108		$	(141,568	)	$	(14,655	)	$	74,340

												*Accumulated*
	*Number*					*Additional*						*Other*			*Total*
	*of Shares*			*Common*		*Paid-in*			*Accumulated*			*Comprehensive*			*Stockholders*’
	*Issued*			*Stock*		*Capital*			*Deficit*			*Loss*			*Equity*
Balance at December 31, 2021		41,143		$	452	$	225,650		$	(132,674	)	$	(10,027	)	$	83,401
Stock option exercises		11			-		31			-			-			31
Stock purchase plan																			91			-		215			-			-			215
Vesting of restricted stock units		151			-		-			-			-			-			287			-		-			-			-			-
Shares withheld for taxes		(64	)		-		(501	)		-			-			(501	)		(54	)		-		(295	)		-			-			(295	)
Stock-based compensation expense		-			-		1,023			-			-			1,023			-			-		1,102			-			-			1,102
Net loss		-			-		-			(6,880	)		-			(6,880	)		-			-		-			(980	)		-			(980	)
Other comprehensive loss		-			-		-			-			(699	)		(699	)
Balance at March 31, 2022		41,241		$	452	$	226,203		$	(139,554	)	$	(10,726	)	$	76,375
Other comprehensive income																			-			-		-			-			601			601
Balance at June 30, 2023																			42,687		$	457	$	231,533		$	(142,548	)	$	(14,054	)	$	75,388

												Accumulated
Three Months Ended	*Number*					*Additional*						*Other*			*Total*
June 30, 2022	*of Shares*			*Common*		*Paid-in*			*Accumulated*			*Comprehensive*			*Stockholders*’
	*Issued*			*Stock*		*Capital*			*Deficit*			*Loss*			*Equity*
Balance at March 31, 2022		41,241		$	452	$	226,203		$	(139,554	)	$	(10,726	)	$	76,375
Stock option exercises		5			1		11			-			-			12
Stock purchase plan		78			-		239			-			-			239
Vesting of restricted stock units		244			-		-			-			-			-
Shares withheld for taxes		(68	)		-		(279	)		-			-			(279	)
Stock-based compensation expense		-			-		1,239			-			-			1,239
Net income		-			-		-			2,435			-			2,435
Other comprehensive loss		-			-		-			-			(2,517	)		(2,517	)
Balance at June 30, 2022		41,500		$	453	$	227,413		$	(137,119	)	$	(13,243	)	$	77,504

												Accumulated
Six Months Ended	*Number*					*Additional*						*Other*			*Total*
June 30, 2023	*of Shares*			*Common*		*Paid-in*			*Accumulated*			*Comprehensive*			*Stockholders*’
	*Issued*			*Stock*		*Capital*			*Deficit*			*Loss*			*Equity*
Balance at December 31, 2022		42,082		$	454	$	229,008		$	(142,190	)	$	(15,052	)	$	72,220
Stock option exercises		212			3		506			-			-			509
Stock purchase plan		91			-		215			-			-			215
Vesting of restricted stock units		412			-		-			-			-			-
Shares withheld for taxes		(110	)		-		(451	)		-			-			(451	)
Stock-based compensation expense		-			-		2,255			-			-			2,255
Net loss		-			-		-			(358	)		-			(358	)
Other comprehensive income		-			-		-			-			998			998
Balance at June 30, 2023		42,687		$	457	$	231,533		$	(142,548	)	$	(14,054	)	$	75,388

												Accumulated
Six Months Ended	*Number*					*Additional*						*Other*			*Total*
June 30, 2022	*of Shares*			*Common*		*Paid-in*			*Accumulated*			*Comprehensive*			*Stockholders*’
	*Issued*			*Stock*		*Capital*			*Deficit*			*Loss*			*Equity*
Balance at December 31, 2021		41,143		$	452	$	225,650		$	(132,674	)	$	(10,027	)	$	83,401
Stock option exercises		16			1		42			-			-			43
Stock purchase plan		78			-		239			-			-			239
Vesting of restricted stock units		395			-		-			-			-			-
Shares withheld for taxes		(132	)		-		(780	)		-			-			(780	)
Stock-based compensation expense		-			-		2,262			-			-			2,262
Net loss		-			-		-			(4,445	)		-			(4,445	)
Other comprehensive loss		-			-		-			-			(3,216	)		(3,216	)
Balance at June 30, 2022		41,500		$	453	$	227,413		$	(137,119	)	$	(13,243	)	$	77,504

		Three Months Ended March 31,							Six Months Ended June 30,
		2023			2022				2023			2022
Cash flows from operating activities:
Net income (loss)		$	622		$	(6,880	)
Adjustments to reconcile net income (loss) to net cash provided by (used in) operating activities:
Net loss									$	(358	)	$	(4,445	)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:
Depreciation			333			382				665			758
Amortization of intangible assets			1,388			1,466				2,777			2,920
Amortization of deferred financing costs			70			70				140			140
Stock-based compensation expense			1,153			1,023				2,255			2,262
Deferred income taxes and other			(55	)		(123	)			86			1,040
Unrealized loss on equity securities - Note 14										1,581			-
Convertible Preferred Stock received in Biostage Settlement - Note 14										-			(3,900	)
Gain on sale of product line			(403	)		-				(403	)		-
Changes in operating assets and liabilities:
Accounts receivable			(923	)		1,506				(68	)		3,587
Inventories			(292	)		(1,308	)			398			(2,667	)
Other assets			(308	)		(466	)			(1,268	)		(250	)
Accounts payable and accrued expenses			(150	)		2,729				(270	)		(435	)
Deferred revenue			741			(300	)			445			(611	)
Other liabilities			(364	)		(85	)			(616	)		(575	)
Net cash provided by (used in) operating activities			1,812			(1,986	)			5,364			(2,176	)
Cash flows from investing activities:
Additions to property, plant and equipment			(224	)		(471	)			(741	)		(913	)
Acquisition of intangible assets										(108	)		-
Proceeds from sale of product line			512			-				512			-
Net cash provided by (used in) investing activities			288			(471	)
Net cash used in investing activities										(337	)		(913	)
Cash flows from financing activities:
Borrowing on bank line of credit			1,500			1,500
Repayment on bank line of credit			(2,500	)		-
Borrowing from revolving line of credit										2,500			5,300
Repayment of revolving line of credit										(5,450	)		(3,600	)
Repayment of term debt			(1,841	)		(936	)			(2,591	)		(1,686	)
Proceeds from exercise of stock options and employee stock purchase plan			104			31				724			282
Taxes paid related to net share settlement of equity awards			(156	)		(501	)			(451	)		(780	)
Net cash (used in) provided by financing activities			(2,893	)		94
Net cash used in financing activities										(5,268	)		(484	)
Effect of exchange rate changes on cash			74			(25	)			57			11
Decrease in cash and cash equivalents			(719	)		(2,388	)			(184	)		(3,562	)
Cash and cash equivalents at beginning of period			4,508			7,821				4,508			7,821
Cash and cash equivalents at end of period		$	3,789		$	5,433			$	4,324		$	4,259
Supplemental disclosures of cash flow information:	Supplemental disclosures of cash flow information:							Supplemental disclosures of cash flow information:
Cash paid for interest		$	1,172		$	383			$	2,148		$	845
Cash paid for income taxes, net of refunds		$	(134	)	$	107			$	115		$	352

The unaudited consolidated financial statements of Harvard Bioscience, Inc. and its wholly-owned subsidiaries (collectively, the “Company”) as of ~~March 31,~~June 30, 2023 and for the three and sixmonths ended ~~March 31,~~June 30, 2023 and 2022, have been prepared by the Company pursuant to the rules and regulations of the Securities and Exchange Commission (the “SEC”). Certain information and footnote disclosures normally included in financial statements prepared in accordance with U.S. generally accepted accounting principles (“U.S. GAAP”) have been condensed or omitted pursuant to such rules and regulations. The December 31, 2022, consolidated balance sheet was derived from audited financial statements but does not include all disclosures required by U.S. GAAP. However, the Company believes that the disclosures are adequate to make the information presented not misleading. These unaudited consolidated financial statements should be read in conjunction with the consolidated financial statements and the notes thereto included in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2022.

In the opinion of management, all adjustments, which include normal recurring adjustments necessary to present a fair statement of financial position as of ~~March 31,~~June 30, 2023, results of operations and comprehensive income (loss) and cash flows for the three and sixmonths ended ~~March 31,~~June 30, 2023 and 2022, as applicable, have been made. The results of operations for the three and sixmonths ended ~~March 31,~~June 30, 2023, are not necessarily indicative of the operating results for the full fiscal year or any future periods.

The accounting policies underlying the accompanying unaudited consolidated financial statements are set forth in Note 2 to the consolidated financial statements included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2022. ~~There~~Except as described below, there have been no material changes in the Company’s significant accounting policies during the three and sixmonths ended ~~March 31,~~June 30, 2023.

Equity securities traded in active markets are marked to market at each balance sheet date based on their prices as quoted on the relevant stock exchange. Fair value mark-to-market adjustments are recorded as non-operating gains (losses) in the consolidated statement of operations. The Company’s investments in marketable equity securities are classified in the consolidated balance sheet based on the nature of the securities and their availability for use in current operations.

The global supply chain has experienced significant disruptions over the last few years due to electronic component and labor shortages and other macroeconomic factors which have emerged since the onset of COVID-~~19,~~19. ~~leading~~This has led to increased cost of freight, purchased materials, and manufacturing labor costs, while also delaying customer shipments. Additionally, the global economy has recently experienced increasing economic uncertainty, including inflationary pressure, rising interest rates, and significant fluctuations in exchange rates. ~~The COVID-~~19 ~~pandemic has also caused significant economic disruption, including shutdowns that affected various regions in China throughout~~ ~~2022.~~These conditions have negatively impacted the Company’s past business, results of operations, and cash flow.

The Company believes that these global economic uncertainties ~~and supply chain trends~~ will continue through 2023. ~~The COVID-~~19 ~~pandemic continues to evolve, and the future impact of the pandemic is difficult to predict.~~ If these factors are prolonged or are more severe than anticipated, the Company’s business, results of operations, and cash flow ~~would likely~~ may be materially impacted.

In January 2017, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) 2017-04, ~~Intangibles—~~Intangibles—Goodwill and Other (Topic 350): Simplifying the Test for Goodwill Impairment (“ASU 2017-04”), which eliminates the performance of Step 2 from the goodwill impairment test. In performing its annual or interim impairment testing, an entity will instead compare the fair value of the reporting unit with its carrying amount and recognize any impairment charge for the amount by which the carrying amount exceeds the reporting unit’s fair value. Additionally, an entity should consider income tax effects from any tax-deductible goodwill on the carrying amount of the reporting unit when measuring the goodwill impairment loss. ~~ASU~~ ~~2017~~-04 ~~will be effective for the Company for fiscal years beginning after~~ ~~December 15, 2022.~~ The Company adopted ASU 2016-13 effective January 1, 2023 with no impact to the consolidated financial statements. The Company will perform future goodwill impairment test according to ASU 2017-04.

In September 2016, the FASB issued ASU No. 2016-13, Financial ~~Instruments—~~Instruments—Credit Losses (Topic 326): Measurement of Credit Losses on Financial Instruments (‘ (“ASU 2016-~~13’~~13”), which amends the impairment model by requiring entities to use a forward-looking approach based on expected losses rather than incurred losses to estimate credit losses on certain types of financial instruments, including trade receivables. This may result in the earlier recognition of allowances for losses. The FASB issued several ASUs after ASU 2016-13 to clarify implementation guidance and to provide transition relief for certain entities. ~~ASU~~ ~~2016~~-13 ~~will be effective for the Company for fiscal years beginning after~~ ~~December 15, 2022,~~ ~~with early adoption permitted.~~ The Company adopted ASU 2016-13 effective January 1, 2023, which resulted in an immaterial impact to the consolidated financial statements.

The change in the carrying amount of goodwill for the ~~three~~six months ended ~~March 31,~~June 30, 2023 is as follows:

Identifiable intangible assets at ~~March 31,~~June 30, 2023 and December 31, 2022 consist of the following:

Intangible asset amortization expense was $1.4 million and $1.5 million for the three months ended ~~March 31,~~June 30, 2023 and 2022, respectively, and $2.8 million and $2.9 million for the six months ended June 30, 2023 and 2022, respectively. Estimated amortization expense of existing amortizable intangible assets for each of the five succeeding years and thereafter as of ~~March 31,~~June 30, 2023, is as follows:

The following tables provide details of selected balance sheet items as of the periods indicated:

~~In connection with the~~ ~~2014~~ acquisitions of Multi Channel Systems MCS GmbH (“MCS”), the Company entered into a facility lease agreement with the former principal owner of MCS who became an employee of the Company at the time of the acquisition and subsequently retired in ~~2021.~~ ~~The MCS agreement expires on~~ ~~December 31, 2024.~~ ~~Pursuant to this lease agreement, the Company made rent payments of approximately $0.1 million for each of the~~ ~~three~~ ~~months ended~~ ~~March 31, 2023~~ ~~and~~ ~~2022.~~

The Company has noncancelable operating leases for offices, manufacturing facilities, warehouse space, automobiles and equipment expiring at various dates through 2030.

The components of lease expense for the three and sixmonths ended ~~March 31,~~June 30, 2023 and 2022, are as follows:

Supplemental cash flow information related to the Company's operating leases ~~was~~is as follows:

Supplemental balance sheet information related to the Company’s operating leases are as follows:

Future minimum lease payments for operating leases, with initial terms in excess of one year at ~~March 31,~~June 30, 2023, are as follows:

As of ~~March 31,~~June 30, 2023 and December 31, 2022, the Company’s borrowings ~~were~~are as follows:

OnIn December, ~~22,~~ 2020, the Company entered into a Credit Agreement (the “Credit Agreement”) with Citizens Bank, N.A., Wells Fargo Bank, National Association, and Silicon Valley Bank (together, the “Lenders”). All commitments and obligations under the Credit Agreement previously held by Silicon Valley Bank have now been assumed by ~~Silicon Valley Bridge~~First-Citizens Bank ~~N. A.~~& Trust Company. The Credit Agreement provides for a term loan of $40.0 million and a $25.0 million senior revolving credit facility (including a $10.0 million sub-facility for the issuance of letters of credit and a $10.0 million swingline loan sub facility) (collectively, the “Credit Facility”). The Company’s obligations under the Credit Agreement are guaranteed by certain of the Company’s direct, domestic wholly-owned subsidiaries; none of the Company’s direct or indirect foreign subsidiaries has guaranteed the Credit Facility. The Company’s obligations under the Credit Agreement are secured by substantially all of the assets of Harvard Bioscience, Inc., and each guarantor (including all or a portion of the equity interests in certain of the Company’s domestic and foreign subsidiaries). The Credit Facility matures on December 22, 2025. Issuance costs of $1.4 million are amortized over the contractual term to maturity date on a straight-line basis, which approximates the effective interest method. Available and unused borrowing capacity under the revolving line of credit was ~~$10.5~~$12.4 million as of ~~March 31,~~June 30, 2023 based on the Credit Agreement, as ~~amended, pursuant to the~~ ~~April 2022~~ ~~Amendment and~~ ~~November 2022~~ ~~Amendment (both described below).~~amended. Total revolver borrowing capacity is limited by the consolidated net leverage ratio as defined under the amended Credit Agreement.

Borrowings under the amended Credit Facility will, at the option of the Company, bear interest at either (i) a rate per annum based on the Secured Overnight Financing Rate (“SOFR”) for an interest period of one, two, three or six months, plus an applicable interest rate margin determined as provided in the Credit Agreement, as amended (a “SOFR Loan”), or (ii) an alternative base rate plus an applicable interest rate margin, each as determined as provided in the Credit Agreement (an “ABR Loan”). SOFR interest under the Credit Agreement is subject to applicable market rates and a floor of 0.50%. The alternative base rate is based on the Citizens Bank prime rate or the federal funds effective rate of the Federal Reserve Bank of New York and is subject to a floor of 1.0%. The applicable interest rate margin varies from 2.0% per annum to 3.25% per annum for SOFR Loans, and from 1.5% per annum to 3.0% per annum for ABR Loans, in each case depending on the Company’s consolidated leverage ratio and is determined in accordance with a pricing grid set forth in the Credit Agreement. Interest on SOFR Loans is payable in arrears on the last day of each applicable interest period, and interest on ABR Loans is payable in arrears at the end of each calendar quarter. There are no prepayment penalties in the event the Company elects to prepay and terminate the Credit Facility prior to its scheduled maturity date, subject to SOFR Loan breakage and redeployment costs in certain circumstances.

The effective interest rate on the Company borrowings for the three months ended ~~March 31,~~June 30, 2023 and 2022, was ~~7.9 %~~8.3% and ~~3.1%~~4.0%, respectively, and for thesix months ended June 30, 2023 and 2022, was 8.1% and 3.6%, respectively. The weighted average interest rate as of ~~March 31,~~June 30, 2023, ~~net~~inclusive of the effect of the Company’s interest rate swaps, was ~~8.0%~~8.1%. The carrying value of the debt approximates fair value because the interest rate under the obligation approximates market rates of interest available to the Company for similar instruments.

The term ~~loans amortize~~loan amortizes in quarterly installments of $0.75 million per quarter for each of the next ~~three~~two quarters and $1.0 million per quarter during the next seven quarters thereafter, with a balloon payment at maturity. Furthermore, within ninety days after the end of the Company’s fiscal year, the term ~~loans~~loan may be permanently reduced pursuant to certain mandatory prepayment events including an annual “excess cash flow sweep” of 50% of the consolidated excess cash flow, as defined in the agreement; provided that, in any fiscal year, any voluntary prepayments of the term loans shall be credited against the Company’s “excess cash flow” prepayment obligations on a dollar-for-dollar basis for such fiscal year. As of December 31, 2022, the current portion of long-term debt included an excess cash flow sweep of $1.1 million which was paid onduring the quarter ended March 31, 2023. Amounts outstanding under the revolving credit facility can be repaid at any time but are due in full at maturity.

The Credit Agreement, as amended, includes customary affirmative, negative, and financial covenants binding on the Company. The negative covenants limit the ability of the Company, among other things, to incur debt, incur liens, make investments, sell assets and pay dividends on its capital stock. The financial covenants include a maximum consolidated net leverage ratio and a minimum consolidated fixed charge coverage ratio. The Credit Agreement, as amended, also includes customary events of default.

On April 28, 2022, the Company entered into an amendment to the Credit Agreement (the “April 2022 Amendment”) pursuant to which the Lenders and administrative agent, among other things, modified the financial covenant relating to the consolidated net leverage ratio, and consented to the Biostage Settlement (as defined below), including without limitation the receipt by the Company of convertible preferred stock in Biostage, Inc. (“Biostage”) and the securities issuable upon conversion thereof, as partial payment for Biostage’s indemnification obligations in connection with the Biostage Settlement. See Note 1413 for information regarding the Biostage Settlement. In consideration for the April 2022 Amendment, the Company paid fees of $0.2 million to the Lenders and administrative agent.

On November 8, 2022, the Company entered into a subsequent amendment to the Credit Agreement (the “November 2022 Amendment”) pursuant to which, among other things the Lenders and administrative agent modified the financial covenant relating to the consolidated net leverage ratio, and the definition of Consolidated EBITDA used in the calculation of certain financial covenants, including to exclude non-cash inventory charges related to the Company’s decision to discontinue non-strategic products. In consideration for the November 2022 Amendment, the Company paid fees of $0.2 million to the Lenders and administrative agent.

The Company was in compliance with the covenants of the Credit Agreement, as amended, as of ~~March 31,~~June 30, 2023.

The Company monitors interest rate risk attributable to both its outstanding and forecasted debt obligations by the use of cash flow sensitivity analysis, which estimates the expected impact of changes in interest rates on the Company’s future cash. The Company uses interest-rate-related derivative instruments to manage its exposure related to changes in interest rates on its variable-rate debt instruments. The Company does not enter into derivative instruments for any purpose other than cash flow hedging.

By using derivative financial instruments to hedge exposure to changes in interest rates, the Company exposes itself to credit risk and market risk. Credit risk is the failure of the counterparty to perform under the terms of the derivative contract. When the fair value of a derivative contract is positive, the counterparty owes the Company, which creates credit risk for the Company. When the fair value of a derivative contract is negative, the Company owes the counterparty and, therefore, the Company is not exposed to the counterparty’s credit risk in those circumstances. The Company minimizes counterparty credit risk in derivative instruments by entering into transactions with carefully selected major financial institutions based upon their credit profile.

Market risk is the adverse effect on the value of a derivative instrument that results from a change in interest rates. The market risk associated with interest-rate contracts is managed by establishing and monitoring parameters that limit the types and degree of market risk that may be undertaken. The Company monitors interest rate risk attributable to both its outstanding and forecasted debt obligations by the use of cash flow sensitivity analysis, which estimates the expected impact of changes in interest rates on the Company’s future cash flows.

On February 28, 2023, the Company entered into an interest rate swap contract to improve the predictability of cash flows from interest payments related to its variable, ~~SOFR based~~SOFR-based debt. The swap contract has a notional amount of ~~$31.8~~$30.3 million as of ~~March 31,~~June 30, 2023 and matures on December 22, 2025. This swap contract effectively converts the SOFR-based variable portion of the interest payable under the Credit Agreement into fixed-rate debt at an annual rate of 4.75%. The swap contract does not impact the additional interest related to the applicable interest rate margin as discussed above in Note 76, Long-Term Debt. The interest rate swap is considered an effective cash flow hedge, and as a result, the net gains or losses on such instrument are reported as a component of other comprehensive income (loss) (“OCI”) in the consolidated financial statements and are reclassified as net income when the underlying hedged interest impacts earnings. A qualitative and quantitative assessment over the hedge effectiveness is performed on a quarterly basis unless facts and circumstances indicate that the hedge may no longer be highly effective.

The following table presents the notional amount and fair value of the Company’s derivative ~~instruments~~instrument as of ~~March 31,~~June 30, 2023:

(a) See Note 98 for the fair value measurements related to ~~these~~this financial ~~instruments.~~instrument.

The ~~portion~~following table summarizes the effect of ~~the interest rate swap that was reclassified to interest expense from accumulated other comprehensive loss~~derivatives designated as cash flow hedging instruments for the three and sixmonths ended ~~March 31, 2023~~ June 30, 2023:~~was~~ ~~not~~ ~~significant.~~

The following tables present the fair value hierarchy for those assets or liabilities measured at fair value on a recurring basis:

The Company uses the market approach technique to value its financial assets and liabilities. The Company’s financial assets and liabilities carried at fair value include, when applicable, investments in common stock and derivative instruments used to hedge the Company’s interest rate risks. The fair value of the Company’s investment in common stock of Biostage was based on the closing price ~~per~~as quoted on the OTCQB Marketplace at the reporting date. The fair value of the Company’s interest rate swap agreements was based on SOFR yield curves at the reporting date.

Stock-based awards consist of stock options, time-based restricted stock units, ~~(“RSUs”), performance-based RSUs (“PRSUs”)~~market condition restricted stock units, and shares issued under the Company’s employee stock purchase ~~plan (the “ESPP”).~~plan. Activity under the Company’s equity incentive plans for the ~~three~~six months ended ~~March 31,~~June 30, 2023 ~~was~~is as follows:

Stock-based compensation expense ~~related to stock options, RSUs, PRSUs, and the ESPP~~ for the three and sixmonths ended ~~March 31,~~June 30, 2023 and 2022 ~~was~~is allocated as follows:

As of ~~March 31,~~June 30, 2023, the total compensation costs related to unvested awards not yet recognized is ~~$8.4~~$7.4 million and the weighted average period over which it is expected to be recognized is approximately ~~2.1~~1.9 years. The Company did not capitalize any stock-based compensation.

The weighted average estimated fair value of ~~PRSUs~~the market condition restricted stock awards that were granted during the ~~three~~six months ended ~~March 31,~~June 30, 2023 was $2.61 per unit. The ~~following assumptions were used to~~ estimate of the fair value ~~of PRSUs granted during the~~ ~~three~~ ~~months ended~~ ~~March 31, 2023~~ was determined using a Monte-Carlo valuation ~~simulation:~~simulation, which included the following assumptions:

Basic earnings (loss) per share (EPS) is calculated by dividing net income (loss) by the number of weighted average shares of common stock outstanding during the period. The calculation of diluted earnings per share assumes conversion of stock options ~~RSUs,~~ and ~~PRSUs~~restricted stock units into common stock using the treasury method. The weighted average number of shares used to compute basic and diluted EPS ~~consists~~consisted of the following:

The following tables represent a disaggregation of revenue from contracts with customers for the three and sixmonths ended ~~March 31,~~June 30, 2023 and 2022:

The following tables represent a disaggregation of revenue by geographic destination for the three and sixmonths ended ~~March 31,~~June 30, 2023 and 2022:

No customer ~~accounted~~accounts for more than 10% of revenues for the three and sixmonths ended ~~March 31,~~June 30, 2023 and 2022. At ~~March 31,~~June 30, 2023 and December 21, 2022, no customer ~~accounted~~accounts for more than 10% of net accounts receivable.

The following tables provide details of deferred revenue as of the periods indicated:

During each of the three months ended ~~March 31,~~June 30, 2023 and 2022, the Company recognized revenue of ~~$1.0~~$0.6 million from deferred revenue existing at December 31, 2022 and 2021, respectively. During the six months ended June 30, 2023 and 2022, the Company recognized revenue of $1.6 million and ~~$0.7~~$1.3 million from deferred revenue existing at December 31, 2022 and 2021, respectively.

The allowance for expected credit losses on receivables is used to present accounts receivable, net at an amount that represents the Company’s estimate of the related transaction price recognized as revenue. The allowance represents an estimate of expected credit losses over the lifetime of the receivables, even if the loss is considered remote, and reflects expected recoveries of amounts previously written-off. The Company estimates the allowance on the basis of specifically identified receivables that are evaluated individually for impairment and an analysis of the remaining receivables determined by reference to past default experience. The Company considers the need to adjust historical information to reflect the extent to which current conditions and reasonable forecasts are expected to differ from the conditions that existed for the historical period considered. Losses on receivables have not historically been significant.

Management judgments are used to determine when to charge off uncollectible trade accounts receivable. The Company bases these judgments on the age of the receivable, credit quality of the customer, current economic conditions, and other factors that may affect a customer’s ability and intent to pay. Customers are generally not required to provide collateral for purchases.

The determination of the annual effective tax rate is based upon a number of significant estimates and judgments, including the estimated annual pretax income in each tax jurisdiction in which the Company operates and the development of tax planning strategies during the year. In addition, as a global commercial enterprise, the Company’s tax expense can be impacted by changes in tax rates or laws, the finalization of tax audits and reviews and other factors that cannot be predicted with certainty. As such, there can be significant volatility in interim tax provisions.

Income tax (benefit) expense ~~(benefit) was $0.6~~is $(1.1) million and ~~$(0.1)~~$1.0 million for the three months ended ~~March 31,~~June 30, 2023 and 2022, respectively, and is $(0.5) million and $0.8 million for the six months ended June 30, 2023 and 2022, respectively. The effective tax rates for the three months ended ~~March 31,~~June 30, 2023 and 2022, ~~were 48.5%~~are 53.3% and ~~2.0%~~28.8%, respectively. The effective tax rates for the six months ended June 30, 2023 and 2022, are 59.8% and (23.6)%, respectively.

The difference between the Company’s effective tax rates in 2023 and 2022 compared to the U.S. statutory tax rate of 21% is primarily due to a Global Intangible Low-Taxed Income (“GILTI”) inclusion to taxable income and changes in valuation allowances associated with the Company’s assessment of the likelihood of the recoverability of deferred tax assets. The Company has valuation allowances against substantially all of its net operating loss carryforwards and tax credit carryforwards.

On April 27, 2022, the Company and Biostage executed a settlement with the plaintiffs in the Biostage Litigation (as defined below) which resolved all claims relating to the litigation as described in Note 1413 – Litigation Settlement.

The Company is involved in various other claims and legal proceedings arising in the ordinary course of business. After consultation with legal counsel, the Company has determined that the ultimate disposition of such proceedings is not likely to have a material adverse effect on its business, financial condition, results of operations or cash flows. Although unfavorable outcomes in the proceedings are possible, the Company has not accrued loss contingencies relating to any such matters as they are not considered to be probable and reasonably estimable. If one or more of these matters are resolved in a manner adverse to the Company, the impact on the Company’s business, financial condition, results of operations and cash flows could be material.

In addition, the Company has entered into indemnification agreements with its directors. It is not possible to determine the maximum potential liability amount under these indemnification agreements due to the limited history of prior indemnification claims and the unique facts and circumstances involved in each particular agreement. The Company has not recorded any liability for costs related to contingent indemnification obligations as of ~~March 31,~~June 30, 2023.

The Company is ~~also~~ subject to unclaimed property laws in the ordinary course of its business. State escheat laws generally require entities to report and remit abandoned and unclaimed property to the state. Failure to timely report and remit the property can result in assessments that could include interest and penalties, in addition to the payment of the escheat liability itself. The Company is currently undergoing unclaimed property audits conducted by ~~three~~in various states. Based on the current stage of the audits, the Company has not accrued any loss contingencies related to these audits as of ~~March 31,~~June 30, 2023.

On April 14, 2017, representatives for the estate of an individual plaintiff filed a wrongful death complaint with the Suffolk Superior Court, in the County of Suffolk, Massachusetts, against the Company and other defendants, including Biostage, a former subsidiary of the Company that was spun off in 2013, as well as another third party (the “Biostage Litigation”). The complaint sought payment for an unspecified amount of damages and alleged that the plaintiff sustained terminal injuries allegedly caused by products, including one synthetic trachea scaffold and two bioreactors, provided by certain of the named defendants and utilized in connection with surgeries performed by third parties in Europe in 2012 and 2013.

On April 27, 2022, the Company and Biostage executed a settlement with the plaintiffs of the Biostage Litigation and Biostage’s products liability insurance carriers (the “Biostage Settlement”), which resolved all claims by and between the parties and Biostage’s product liability insurance carriers and resulted in the dismissal with prejudice of the wrongful death claim and all claims between the Company, Biostage and the insurance carriers. The Biostage Settlement was entered into solely by way of compromise and settlement and is not in any way an admission of liability or fault by the Company or Biostage. Biostage has indemnified the Company for all losses and expenses, including legal expenses that the Company incurred in connection with the Biostage Litigation and the Biostage Settlement.

During the three months ended March 31, 2022, the Company accrued $5.2 million of costs related to legal fees and the Biostage Settlement. Due to the financial condition of Biostage, the Company determined that it was uncertain as to whether Biostage would be able to meet its indemnification obligation and had fully reserved any receivable from Biostage.

During the three months ended June 30, 2022, ~~and~~ ~~September 30, 2022,~~ the Company recorded credits of $4.9 million ~~and $0.5 million, respectively,~~ to the reserve against the indemnification receivable from Biostage. These adjustments reflected: i) the issuance by Biostage of 4,000 shares of its Series E Convertible Preferred Stock (the “Series E Preferred Stock”) to the Company on June 10, 2022, in satisfaction of $4.0 million of Biostage’s total indemnification obligation, ii) the payment by Biostage of the legal fees associated with the Biostage Settlement, and iii) other accrual adjustments. The Series E Preferred Stock accrued dividends at a rate of 8% per annum that are payable in additional shares of Series E Preferred Stock. The Series E Preferred Stock was initially recorded at an estimated fair value of $3.9 million using a Monte Carlo valuation simulation incorporating information from selected guideline companies.

~~The Series E Preferred Stock ranks senior to all classes~~As of common stock of Biostage and all classes of preferred stock of Biostage (unless the Company consents to Biostage’s issuance of other preferred stock that is senior to or pari passu with the Series E Preferred Stock) and accrues dividends at a rate of 8% per annum that are payable in additional shares of Series E Preferred Stock. Each share of Series E Preferred Stock is convertible at any time at the option of the Company into such number of shares of Biostage common stock determined by dividing (a) the $1,000 face value of the Series E Preferred Stock plus all accrued and unpaid dividends thereon by (b) the average of the volume weighted average trading prices of Biostage’s common stock, which is currently quoted on the OTCQB Marketplace, for the 60 consecutive trading days prior to the conversion. In the event Biostage has a subsequent qualified offering of its common stock, (which is defined as an offering of Biostage common stock that coincides with its uplisting onto Nasdaq, the ~~first~~ ~~subsequent public offering by Biostage, or the~~ ~~first~~ subsequent private placement by Biostage resulting in gross proceeds to Biostage of at least $4,000,000), the Series E Preferred Stock is mandatorily converted into Biostage common stock at the applicable qualified offering price.

~~During the~~ ~~three~~ ~~months ended~~ ~~March~~December 31, ~~2023,~~2022, the ~~Company converted 200 shares of its Series E Preferred Stock into 31,933 shares of Biostage common stock. The market value of this Biostage common stock was $0.2 million at~~ ~~March 31, 2023.~~

~~The~~ book value of the shares of Series E Preferred Stock, inclusive of accrued dividends, ~~as of~~ ~~March 31, 2023~~ iswas $4.0 million and iswas included in the consolidated balance sheet as a component of Other long-term assets. The Company ~~has~~ elected the provisions within ASC 321, Investment Securities, to subsequently measure the Series E Preferred Stock at its original cost minus impairment, if any, plus or minus changes resulting from observable price changes in orderly transactions for the identical or a similar investment of Biostage. As of ~~March~~December 31, ~~2023,~~2022, there ~~have been~~were no observable price changes or indicators of impairment and therefore, there ~~have been~~was no measurement adjustments to the carrying value of the Series E Preferred Stock.

On January 18, 2023, the Company voluntarily converted 200 shares of its Series E Preferred Stock into 31,933 shares of Biostage common stock.

On April 6, 2023, Biostage disclosed that it had completed a private placement of its common stock for an aggregate offering amount of approximately $6.0 million at a purchase price of $6.00 per share. As the proceeds of the private placements were in excess of $4.0 million, the transaction triggered a mandatory conversion of the Company’s remaining Series E Preferred Stock into shares of Biostage common stock at the offering price of $6.00 per share. As of June 30, 2023, the Company held 707,626 shares of Biostage common stock with an estimated fair value of $2.6 million, which has been included in the consolidated balance sheet as a component of Other long-term assets due to the limited trading volumes of Biostage’s common stock on the OTCQB Marketplace.

The Company determines the fair value of its shares of Biostage common stock at each reporting period using prices as quoted on the OTCQB Marketplace. Due to Biostage’s limited operating history, its overall financial condition and the limited trading volumes and liquidity of its common stock, the value of the Company’s investment in Biostage’s common stock could fluctuate considerably or become worthless. During the three months ended June 30, 2023, the Company recorded unrealized losses related to its investment in Biostage common stock of $1.6 million, which was recorded in the Other expense section in the consolidated statements of operations.

On February 17, 2023, the Company completed the disposition of its Hoefer product line for cash consideration of $0.5 million. The carrying value of assets sold was $0.1 million resulting in a gain on disposition of $0.4 million which is recorded in Other income, net in the consolidated statement of operations for the ~~three~~six months ended ~~March 31,~~June 30, 2023. Revenue and gross profit of this disposed product line included in the condensed consolidated statement of operations for the ~~three~~six months ended ~~March 31,~~June 30, 2023, and for the ~~2022~~three ~~are~~and six months ended June 30, 2022, were not significant.

On ~~April 6, 2023,~~ Biostage disclosed that it had completed a private placement with certain investors to purchase shares of Biostage common stock for the aggregate purchase price of approximately $6.0 million at a purchase price of $6.00 per share. As the proceeds of the private placement are in excess of $4.0 million, the transaction triggered a mandatory conversion of the Series E Preferred Stock, plus all accrued dividends, into Biostage common stock as discussed in Note 14 ~~above.~~

On ~~April 6, 2023,~~ all of the Company’s remaining Series E Preferred Stock, plus all accrued dividends, were converted into approximately 675,000 shares of Biostage common stock at the applicable qualified offering price of $6.00 per share. Immediately after the conversion, the Company owned approximately 5% of Biostage’s total common shares outstanding. Due to Biostage’s limited operating history, their overall financial condition and the limited trading volumes and liquidity of their common stock, the value of the Company’s investment in Biostage’s common stock could fluctuate considerably or become worthless.

Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations.

This Quarterly Report on Form 10-Q contains statements that are not statements of historical fact and are forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 (the “Exchange Act”). The forward-looking statements are principally, but not exclusively, contained in “Item 2: Management’s Discussion and Analysis of Financial Condition and Results of Operations.” These statements involve known and unknown risks, uncertainties and other factors that may cause our actual results, performance, or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Forward-looking statements include, but are not limited to, statements about management’s confidence or expectations, and our plans, objectives, expectations, and intentions that are not historical facts. In some cases, you can identify forward-looking statements by terms such as “may,” “will,” “should,” “could,” “would,” “seek,” “expects,” “plans,” “aim,” “anticipates,” “believes,” “estimates,” “projects,” “predicts,” “intends,” “think,” “potential,” “objectives,” “optimistic,” “strategy,” “goals,” “sees,” “new,” “guidance,” “future,” “continue,” “drive,” “growth,” “long-term,” “projects,” “develop,” “possible,” “emerging,” “opportunity,” “pursue” and similar expressions intended to identify forward-looking statements. These statements reflect our current views with respect to future events and are based on assumptions and subject to risks and uncertainties. Given these uncertainties, you should not place undue reliance on these forward-looking statements. We discuss many of these risks in detail in our Annual Report on Form 10-K for the year ended December 31, 2022 and our other filings with the SEC. You should carefully review all of these factors, as well as other risks described in our public filings, and you should be aware that there may be other factors, including factors of which we are not currently aware, that could cause these differences. Also, these forward-looking statements represent our estimates and assumptions only as of the date of this report. We may not update these forward-looking statements, even though our situation may change in the future, unless we have obligations under the federal securities laws to update and disclose material developments related to previously disclosed information. Harvard Bioscience, Inc. is referred to herein as “we,” “our,” “us,” and “the Company.”

The global supply chain has experienced significant disruptions over the last few years due to electronic component and labor shortages and other macroeconomic factors which have emerged since the onset of ~~COVID-19, leading~~COVID-19. This has led to increased cost of freight, purchased materials, and manufacturing labor costs, while also delaying customer shipments. Additionally, the global economy has recently experienced increasing economic uncertainty, including inflationary pressure, rising interest rates, and significant fluctuations in exchange rates. ~~The COVID-19 pandemic has also caused significant economic disruption, including shutdowns that affected various regions in China throughout 2022.~~ These conditions have negatively impacted our past business, results of operations, and cash flow.

We believe that these global economic uncertainties ~~and supply chain trends~~ will continue through 2023. ~~The COVID-19 pandemic continues to evolve, and the future impact of the pandemic is difficult to predict.~~ If these factors are prolonged or are more severe than anticipated, our business, results of operations, and cash flow may be materially impacted.

Three months ended ~~March 31,~~June 30, 2023 compared to three months ended ~~March 31,~~June 30, 2022.

~~Revenues increased $1.2~~Revenue decreased $0.4 million, or ~~4.2%~~1.5%, ~~to $30.0 million for the three months ended March 31, 2023, compared~~ to $28.8 million for the three months ended ~~March 31,~~June 30, 2023, compared to $29.2 million for the three months ended June 30, 2022. ~~The increase~~This decline included a decrease of $1.6 million in ~~revenue was primarily due to growth in preclinical products, which was partially offset by reduced~~ revenue from the discontinuation of non-strategic cellular and molecular products ~~and unfavorable currency impacts.~~in the second half of 2022, partially offset by revenue growth in preclinical products.

Gross profit ~~increased $2.2~~was $16.7 million ~~or 13.4%, to $18.3~~for three months ended June 30, 2023, compared with $16.6 million for the three months ended ~~March 31, 2023 compared with $16.2 million~~June 30, 2022. Gross margin increased to 58.0% for the three months ended ~~March 31, 2022. Gross margin increased to 61.2%~~June 30, 2023, compared with 57.0% for the three months ended ~~March 31, 2023, compared with 56.2% for the three months ended March 31,~~June 30, 2022. The increase in gross margin was due primarily to ~~the increase in revenue,~~ a higher mix of preclinical products which ~~carries a~~generally have higher gross margin than our other product lines, and ~~the discontinuation in~~reduced revenue from lower margin products discontinued during the second half of ~~2022 of lower margin non-strategic products.~~

~~The~~2022. Additionally, during the three months ended June 30, 2023, we aligned our global ~~supply chain has experienced significant disruptions due~~inventory costing process, which had an unfavorable impact to ~~electronic components and labor shortages and other macroeconomic factors, leading to increased costs. We expect that these supply chain trends will continue through the rest of 2023.~~gross margin.

Sales and marketing expenses decreased ~~$0.7~~$0.4 million, or ~~10.6%~~6.2%, to ~~$6.0~~$6.2 million for the three months ended ~~March 31,~~June 30, 2023, compared to ~~$6.7~~$6.6 million ~~during~~for the ~~same period in~~three months ended June 30, 2022. The decrease was primarily due to reduced salaries and travel ~~expenses partially offset by increases in variable compensation.~~expenses.

General and administrative expenses ~~were $6.3~~decreased $0.6 million, or 10.5%, to $5.4 million for ~~each of~~ the three months ended ~~March 31,~~June 30, 2023, ~~and~~compared with $6.0 million for the three months ended June 30, 2022. This ~~includes decreases in~~decrease was primarily due to reduced consulting costs ~~associated with enterprise-level operational improvement initiatives~~partially offset by increases in salaries and variable compensation.

Research and development expenses decreased ~~$0.3~~$0.5 million, or ~~10.0%~~15.4%, to ~~$2.9~~$3.0 million for the three months ended ~~March 31,~~June 30, 2023, compared with ~~$3.2~~$3.5 million for the three months ended ~~March 31,~~June 30, 2022. The decrease was primarily due to reduced salaries and consulting costs partially offset by increases in variable compensation.

Amortization of intangible asset expenses were $1.4 million for the three months ended ~~March 31,~~June 30, 2023, compared with $1.5 million for the three months ended ~~March 31,~~June 30, 2022. Amortization expense decreased as we completed the amortization of certain intangible assets ~~discontinued~~ during 2022.

During the three months ended March 31, 2022, we accrued $5.2 million of costs related to legal fees in connection with the Biostage Litigation and the Biostage Settlement. Due to the financial condition of Biostage, we determined that it was uncertain as to whether Biostage would be able to meet its indemnification obligation and had fully reserved any receivable from Biostage.

During the three months ended June 30, 2022, ~~and September 30, 2022,~~ we recorded ~~credits~~a credit of $4.9 million ~~and $0.5 million, respectively~~ consisting of adjustments to the reserve against an indemnification receivable from Biostage to reflect: i) the issuance by Biostage of Series E Preferred Stock to us on June 10, 2022, in satisfaction of $4.0 million of Biostage’s total indemnification obligations, ii) the payment by Biostage of legal fees associated with the Biostage Settlement, and iii) other accrual adjustments. The Series E Preferred Stock was initially recorded at an estimated fair value of $3.9 million using a Monte Carlo valuation simulation incorporating information from selected guideline companies.

On April 6, 2023, Biostage disclosed that it had completed a private placement of its common stock for an aggregate offering amount of approximately $6.0 million at a purchase price of $6.00 per share. As the proceeds of the private placements were in excess of $4.0 million, the transaction triggered a mandatory conversion of our Series E Preferred Stock into shares of Biostage common stock at the offering price of $6.00 per share. As of June 30, 2023, we held 707,626 shares of Biostage common stock with an estimated fair value of $2.6 million.

We determine the fair value of our shares of Biostage common stock at each reporting period using prices as quoted on the OTCQB Marketplace. During the three months ended June 30, 2023, we recorded unrealized losses related to our investment in Biostage common stock of $1.6 million. Due to Biostage’s limited operating history, its overall financial condition and the limited trading volumes and liquidity of its common stock, the value of our investment in Biostage’s common stock could fluctuate considerably or become worthless.

Interest expense increased ~~$0.6~~$0.4 million, or ~~153.6%~~82.7%, to ~~$1.0~~$0.9 million for the three months ended ~~March 31,~~June 30, 2023, compared with ~~$0.4~~$0.5 million for the three months ended ~~March 31,~~June 30, 2022. The increase was the result of higher interest costs in a rising rate ~~environment.~~environment, which was partially offset by lower average borrowings during the period.

Income tax (benefit) expense ~~(benefit)~~ for the three months ended ~~March 31,~~June 30, 2023 was ~~$0.6~~$(1.1) million and ~~was $(0.1) million~~ for the three months ended ~~March 31, 2022.~~June 30, 2022 was $1.0 million. The effective tax rates for the three months ended ~~March 31,~~June 30, 2023 and 2022 were ~~48.5%~~53.3% and ~~2.0%~~28.8%, respectively. The difference between our effective tax rates infor the three months ended June 30, 2023 and 2022, compared to the U.S. statutory tax rate of 21% is primarily due to a Global Intangible Low-Taxed Income (“GILTI”) inclusion to taxable income and changes in valuation allowances associated with our assessment of the likelihood of the recoverability of our deferred tax assets. We have valuation allowances against substantially all of our net operating loss carryforwards and tax credit carryforwards.

Six months ended June 30, 2023 compared to six months ended June 30, 2022.

Revenue increased $0.7 million, or 1.3%, to $58.7 million for the six months ended June 30, 2023, compared to $58.0 million for the six months ended June 30, 2022. The increase in revenue was primarily due to revenue growth in preclinical products, which was partially offset by decreases from the discontinuation of non-strategic cellular and molecular products of $2.8M.

Gross profit was $35.0 million for six months ended June 30, 2023 compared with $32.8 million for the six months ended June 30, 2022. Gross margin increased to 59.6% for the six months ended June 30, 2023, compared with 56.6% for the six months ended June 30, 2022. The increase in gross margin was due primarily to the increase in revenue, a higher mix of preclinical products which generally have higher gross margin than our other product lines, and reduced revenue from lower margin products discontinued during the second half of 2022.

Sales and marketing expenses decreased $1.1 million, or 8.4%, to $12.2 million for the six months ended June 30, 2023, compared to $13.3 million for the six months ended June 30, 2022. The decrease was primarily due to reduced salaries and travel expenses partially offset by increases in variable compensation.

General and administrative expenses decreased $0.6 million, or 5.0%, to $11.7 million for the six months ended June 30, 2023, compared with $12.3 million for the six months ended June 30, 2022. The decrease was primarily due to reduced consulting costs partially offset by increases in salaries and variable compensation.

Research and development expenses decreased $0.9 million, or 12.8%, to $5.9 million for the six months ended June 30, 2023, compared with $6.7 million for the six months ended June 30, 2022. The decrease was primarily due to reduced salaries and consulting costs partially offset by increases in variable compensation.

Amortization of intangible asset expenses were $2.8 million for the six months ended June 30, 2023, compared with $2.9 million for the six months ended June 30, 2022. Amortization expense decreased as we completed the amortization of certain intangible assets during 2022.

During the six months ended June 30, 2022, we incurred a net expense of $0.3 million related to the Biostage Settlement consisting of $5.2 million in settlement and legal expenses accrued during the three months ended March 31, 2022 offset by a credit of $4.9 million recorded during the three months ended June 30, 2022 as discussed above, related to adjustments to the reserves against the indemnification receivable from Biostage.

We determine the fair value of our shares of Biostage common stock at each reporting period using prices as quoted on the OTCQB Marketplace. During the six months ended June 30, 2023, we recorded unrealized losses related to our investment in Biostage common stock of $1.6 million. Due to Biostage’s limited operating history, its overall financial condition and the limited trading volumes and liquidity of its common stock, the value of our investment in Biostage’s common stock could fluctuate considerably or become worthless.

Interest expense increased $1.0 million, or 113.0 %, to $1.9 million for the six months ended June 30, 2023, compared with $0.9 million for the six months ended June 30, 2022. The increase was the result of higher interest costs in a rising rate environment which was partially offset by lower average borrowings during the period.

Income tax (benefit) expense for the six months ended June 30, 2023 was $(0.5) million and for the six months ended June 30, 2022 was $0.8 million. The effective tax rates for the six months ended June 30, 2023 and 2022 were 59.8% and (23.6)%, respectively. The difference between our effective tax rates for the six months ended June 30, 2023 and 2022, compared to the U.S. statutory tax rate of 21% is primarily due to a GILTI inclusion to taxable income and changes in valuation allowances associated with our assessment of the likelihood of the recoverability of our deferred tax assets. We have valuation allowances against substantially all of our net operating loss carryforwards and tax credit carryforwards.

Our primary sources of liquidity are cash and cash equivalents, internally generated cash flow from operations and our revolving credit facility. Our expected cash outlays relate primarily to cash payments due under our Credit Agreement described below, salaries as well as capital ~~expenditures and payments associated with business improvement initiatives.~~expenditures.

As of ~~March 31,~~June 30, 2023, we held cash and cash equivalents of ~~$3.8~~$4.3 million, compared with $4.5 million at December 31, 2022. Borrowings outstanding were ~~$44.8~~$42.1 million and $47.7 million as of ~~March 31,~~June 30, 2023 and December 31, 2022, respectively.

On December 22, 2020, we entered into a Credit Agreement which provides for a term loan of $40.0 million and a $25.0 million senior revolving credit facility both maturing on December 22, 2025. As of ~~March 31,~~June 30, 2023, the weighted average interest rate on our borrowings, ~~net~~inclusive of the effect of the interest rate swaps, was ~~8.0%~~8.1%, and the available and unused borrowing capacity was ~~$10.5~~$12.4 million. Total revolver borrowing capacity is limited by our consolidated net leverage ratio as defined under the Credit Agreement, as amended. As of ~~March 31,~~June 30, 2023, we ~~are~~were in compliance with the covenants of the Credit Agreement, as amended.

Based on our current operating plans, we expect that our available cash, cash generated from current operations and debt capacity will be sufficient to finance current operations, ~~any costs associated with business improvement initiatives~~ and capital expenditures for at least the next 12 months. This assessment includes consideration of our best estimates of the impact of macroeconomic conditions and the COVID-19 pandemic on our financial results described above. Our forecast of the period of time through which our financial resources will be adequate to support our operations is a forward-looking statement that involves risks and uncertainties, and actual results could vary as a result of a number of factors.

Cash provided by (used in) operating activities was ~~$1.8~~$5.4 million and ~~$(2.0)~~$(2.2) million for the ~~three~~six months ended ~~March 31,~~June 30, 2023 and 2022, respectively. Cash flow from operations for the ~~three~~six months ended ~~March 31,~~June 30, 2023, was greater than the comparable period in the prior year ~~primarily as a result of~~reflecting improved operating ~~profits.~~results. Also, during the six months ended June 30, 2022, we paid approximately $4.0 million in connection with the Biostage Settlement.

Cash ~~provided by~~used in investing activities was $0.3 million for the ~~three~~six months ended ~~March 31,~~June 30, 2023, and primarily consisted of $0.8 million of capital expenditures in manufacturing, information technology infrastructure, and intangible asset acquisitions, offset by $0.5 million from proceeds of the sale our Hoefer product ~~line partially offset by $0.2 million of capital expenditures in manufacturing and information technology infrastructure.~~line. Cash used in investing activities was ~~$(0.5)~~$0.9 million for the ~~three~~six months ended ~~March 31,~~June 30, 2022, and primarily consisted of capital expenditures in manufacturing and information technology infrastructure.

Cash ~~(used in) provided by~~used in financing activities was ~~$(2.9)~~$5.3 million and ~~$0.1~~$0.5 million for the ~~three~~six months ended ~~March 31,~~June 30, 2023 and 2022, respectively. During the ~~three~~six months ended ~~March 31,~~June 30, 2023, debt outstanding under our credit facility decreased by ~~$2.8~~$5.5 million, consisting of net payments against our ~~revolver~~revolving line of ~~$1.0~~credit of $2.9 million, and payments of ~~$1.8~~$2.6 million against the term loan. We also received proceeds of $0.7 million from the exercise of stock options and employee stock purchases and paid $0.5 million for taxes related to net share settlement of equity awards. During the ~~three~~six months ended ~~March 31,~~June 30, 2022, we ~~increased total debt outstanding under~~made payments of $1.7 million against our term loan, which were offset by net drawings against our revolving credit facility ~~by $0.6 million. This increase included $0.9 million paid under the term loan and an increase in revolver borrowings~~ of ~~$1.5~~$1.7 million. We also paid ~~$0.5~~$0.8 million for taxes related to net share settlement of equity awards.

Our international operations in some instances operate in a natural hedge, as we sell our products in many countries and a substantial portion of our revenues, costs and expenses are denominated in foreign currencies, primarily the euro and British pound.

During the three months ended ~~March 31,~~June 30, 2023, the impact of foreign currency exchange rates on our consolidated revenues and expense was not significant. During the six months ended June 30, 2023, changes in foreign currency exchange rates resulted in an unfavorable translation effect on our consolidated revenues of approximately ~~$0.5~~$0.4 million and a favorable effect on expense of approximately ~~$0.5~~$0.4 million.

The gain (loss) associated with the translation of foreign equity into U.S. dollars included as a component of comprehensive income ~~during the three months ended March 31, 2023~~ was ~~$0.8~~$0.2 million ~~compared to a loss of approximately $0.7~~and $(2.5) million for the three months ended ~~March 31, 2022. Currency~~June 30, 2023 and June 30, 2022, respectively, and was $1.0 million and $(3.2) million for the six months ended June 30, 2023 and June 30, 2022, respectively.

In addition, currency exchange rate fluctuations included as a component of net income (loss) ~~during~~resulted in currency losses of approximately $0.1 million and $0.2 million for each of the three months ended ~~March 31,~~June 30, 2023 and ~~March 31,~~ 2022, ~~were not significant.~~respectively, and $0.1 million and $0.2 million for each of the six months ended June 30, 2023 and 2022, respectively.

The critical accounting policies underlying the accompanying unaudited consolidated financial statements are those set forth in Part II, Item 7 included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2022.

For information on recent accounting pronouncements impacting our business, see “Recently Issued Accounting Pronouncements” included in Note 2 to our Condensed Consolidated Financial Statements included in “Part I, Item 1. Financial Statements” of this report.

As of ~~March 31,~~June 30, 2023, the end of the period covered by this report, our management, including our Chief Executive Officer and our ~~Interim~~ Chief Financial Officer, reviewed and evaluated the effectiveness of our disclosure controls and procedures (as defined in Rule 13a-15(e) or 15d-15(e) of the Exchange Act). Based upon management's review and evaluation, our Chief Executive Officer and ~~Interim~~ Chief Financial Officer have concluded that, as of the end of the period covered by this Quarterly Report on Form 10-Q, our disclosure controls and procedures were effective to provide reasonable assurance that information required to be disclosed in our Exchange Act reports is recorded, processed, summarized and reported within the time periods specified by the SEC and is accumulated and communicated to management, including the Chief Executive Officer and ~~Interim~~ Chief Financial Officer, as appropriate, to allow timely decisions regarding required disclosure.

There were no changes in our internal control over financial reporting during the ~~first~~second quarter of fiscal 2023 that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

In designing and evaluating our controls and procedures, management recognizes that any controls and procedures, no matter how well designed and operated, can provide only reasonable assurance of achieving the desired control objectives, and management is required to apply its judgment in evaluating the cost-benefit relationship of possible controls and procedures. Because of the inherent limitations in all control systems, no evaluation of controls can provide absolute assurance that all control issues and instances of fraud within the Company have been detected.

The information included in Note 13 ~~and Note 14~~ to the Condensed Consolidated Financial Statements (Unaudited) included in “Part I, Item 1 Financial Statements” of this quarterly report is incorporated herein by reference.

You should carefully consider the risk factors discussed in Part I, “Item 1A. Risk Factors” in our Annual Report on Form 10-K for the fiscal year ended December 31, 2022, which could materially affect our business, financial position, or future results of operations. The risks described in our Annual Report on Form 10-K are not the only risks we face. Additional risks and uncertainties not currently known to us or that we currently deem to be immaterial may also materially adversely affect our business, financial position, or future results of operations.

There were no unregistered sales of equity securities during the period covered by this report.

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by undersigned thereunto duly authorized.

	Page

PART I - FINANCIAL INFORMATION	3

~~Item 1. Condensed Consolidated Financial Statements (unaudited)~~	3

Item 1. Condensed Consolidated ~~Balance Sheets~~Financial Statements (unaudited)	3

Consolidated Balance Sheets	3

Consolidated Statements of Operations	4

Consolidated Statements of Comprehensive ~~Income (Loss)~~Loss	5

Consolidated Statements of Stockholders' Equity	6

Consolidated Statements of Cash Flows	7

Notes to Unaudited Consolidated Financial Statements	8

Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations	1819

Item 3. Quantitative and Qualitative Disclosures about Market Risk	2225

Item 4. Controls and Procedures	2225

PART II - OTHER INFORMATION	23

~~Item 1. Legal Proceedings~~	2326

~~Item1A. Risk Factors~~Item 1. Legal Proceedings	2326

Item1A. Risk Factors	26

Item 2. Unregistered Sales of Equity Securities and Use of Proceeds.	2326

Item 3. Defaults Upon Senior Securities	2326

Item 4. Mine Safety Disclosures	2326

Item 5. Other Information	2326

Item 6. Exhibits	2326

SIGNATURES	2427

	Three Months Ended March 31,						Three Months Ended June 30,						Six Months Ended June 30,
	2023			2022			2023			2022			2023			2022

Revenues	$	29,975		$	28,778		$	28,759		$	29,208		$	58,734		$	57,986
Cost of revenues		11,629			12,601			12,086			12,571			23,715			25,172
Gross profit		18,346			16,177			16,673			16,637			35,019			32,814

Sales and marketing expenses		5,978			6,687			6,178			6,587			12,156			13,274
General and administrative expenses		6,334			6,325			5,353			5,981			11,687			12,306
Research and development expenses		2,897			3,220			2,957			3,497			5,854			6,717
Amortization of intangible assets		1,388			1,466			1,389			1,454			2,777			2,920
Settlement of litigation, net - Note 14		-			5,191
Litigation settlement - Note 14								-			(4,880	)		-			311
Total operating expenses		16,597			22,889			15,877			12,639			32,474			35,528

Operating income (loss)		1,749			(6,712	)		796			3,998			2,545			(2,714	)

Other expense:
Unrealized loss on equity securities - Note 14								(1,581	)		-			(1,581	)		-
Interest expense		(974	)		(384	)		(941	)		(515	)		(1,915	)		(899	)
Other income, net		432			78
Other (expense) income, net								(372	)		(62	)		60			16
Total other expense		(542	)		(306	)		(2,894	)		(577	)		(3,436	)		(883	)

Income (loss) before income taxes		1,207			(7,018	)
Income tax expense (benefit)		585			(138	)
Net income (loss)	$	622		$	(6,880	)
(Loss) income before income taxes								(2,098	)		3,421			(891	)		(3,597	)
Income tax (benefit) expense								(1,118	)		986			(533	)		848
Net (loss) income							$	(980	)	$	2,435		$	(358	)	$	(4,445	)

Income (loss) per share:
Basic income (loss) per share	$	0.01		$	(0.17	)
(Loss) income per share:
Basic (loss) income per share							$	(0.02	)	$	0.06		$	(0.01	)	$	(0.11	)

Diluted income (loss) per share	$	0.01		$	(0.17	)
Diluted (loss) income per share							$	(0.02	)	$	0.06		$	(0.01	)	$	(0.11	)

Weighted-average common shares:
Basic		42,119			41,219			42,354			41,304			42,204			41,256

Diluted		42,783			41,219			42,354			42,560			42,204			41,256

			March 31, 2023							December 31, 2022								June 30, 2023							December 31, 2022
(in thousands)	Average				Accumulated							Accumulated					Average			Accumulated							Accumulated
Amortizable intangible assets:	Life*		Gross		Amortization			Net		Gross		Amortization			Net		Life*	Gross		Amortization			Net		Gross		Amortization			Net
Distribution agreements/customer relationships		7.0	$	16,226	$	(9,086	)	$	7,140	$	16,124	$	(8,727	)	$	7,397	7	$	16,185	$	(9,323	)	$	6,862	$	16,124	$	(8,727	)	$	7,397
Existing technology		3.0		37,365		(27,196	)		10,169		37,549		(26,482	)		11,067
Existing technology and software development																	3		37,512		(28,140	)		9,372		37,549		(26,482	)		11,067
Trade names and patents		3.5		7,558		(5,428	)		2,130		7,523		(5,197	)		2,326	3		7,539		(5,619	)		1,920		7,523		(5,197	)		2,326
Total amortizable intangible assets			$	61,149	$	(41,710	)	$	19,439	$	61,196	$	(40,406	)	$	20,790		$	61,236	$	(43,082	)	$	18,154	$	61,196	$	(40,406	)	$	20,790
Indefinite-lived intangible assets:									202							224								202							224
Total intangible assets								$	19,641						$	21,014							$	18,356						$	21,014

(in thousands)
2023 (remainder of the year)	$	4,169	$	2,777
2024		5,260		5,255
2025		4,023		4,024
2026		2,362		2,363
2027		1,265		1,266
2028		1,018		1,127
Thereafter		1,342		1,342
Total	$	19,439	$	18,154

*Inventories:*	March 31,		December 31,
(in thousands)	2023		2022		June 30, 2023		December 31, 2022
Finished goods	$	5,144	$	5,223	$	5,748	$	5,223
Work in process		3,660		3,776		4,607		3,776
Raw materials		18,057		17,440		15,734		17,440
Total	$	26,861	$	26,439	$	26,089	$	26,439

(in thousands)
Carrying amount at December 31, 2022	$	56,260	$	56,260
Effect of change in currency translation		358		511
Carrying amount at March 31, 2023	$	56,618
Carrying amount at June 30, 2023			$	56,771

*Other Current Liabilities:*	March 31,		December 31,
(in thousands)	2023		2022		June 30, 2023		December 31, 2022
Compensation	$	3,154	$	3,476	$	3,796	$	3,476
Professional fees		589		392		552		392
Warranty costs		279		268		301		268
Customer credits		2,204		2,368		2,664		2,368
Accrued income taxes		700		-		398		-
Other		1,092		982		1,335		982
Total	$	8,018	$	7,486	$	9,046	$	7,486

Year Ending December 31,
(in thousands)
2023 (remainder of the year)	$	1,605		$	1,075
2024		1,803			1,831
2025		1,065			1,096
2026		1,022			1,047
2027		1,035			1,042
Thereafter		2,965			2,964
Total lease payments		9,495			9,055
Less imputed interest		(2,427	)		(2,277	)
Total operating lease liabilities	$	7,068		$	6,778

	Three Months Ended			Six Months Ended
Derivatives in Hedging Relationships (in thousands)	June 30, 2023			June 30, 2023
Amount of gain recognized in OCI on derivatives (effective portion)	$	475		$	35
Amounts reclassifed from accumulated other comprehensive loss to interest expense		(26	)		(26	)
Total	$	449		$	9

	Fair Value as of March 31, 2023										Fair Value as of June 30, 2023
Assets (Liabilities) (in thousands)	Level 1		Level 2			Level 3		Total
Assets (in thousands)											Level 1		Level 2		Level 3		Total
Equity securities - common stock	$	206	$	-		$	-	$	206		$	2,579	$	-	$	-	$	2,579
Interest rate swap agreements	$	-	$	(440	)	$	-	$	(440	)	$	-	$	9	$	-	$	9

				Weighted														Weighted							Market
	*Stock*			*Average*														*Average*							*Condition*
	*Options*			*Exercise*		*RSUs*			*Grant Date*		*PRSUs*		*Grant Date*		*Stock*			*Exercise*		*Restricted*			*Grant Date*		*Restricted*			*Grant Date*
	*Outstanding*			*Price*		*Outstanding*			*Fair Value*		*Outstanding*		*Fair Value*		*Options*			*Price*		*Stock Units*			*Fair Value*		*Stock Units*			*Fair Value*
Balance at December 31, 2022		1,238,776		$	3.15		1,093,801		$	3.94		646,235	$	4.51
Outstanding at December 31, 2022																1,238,776		$	3.15		1,093,801		$	3.94		646,235		$	4.51
Granted		-			-		1,177,391			2.51		558,958		2.61		-			-		1,296,379			2.81		558,958			2.61
Exercised		(39,618	)		2.63		-			-		-		-		(213,644	)		2.38		-			-		-			-
Vested (RSUs)		-			-		(125,036	)		1.93		-		-		-			-		(295,531	)		2.97		(115,976	)		2.98
Cancelled/Forfeited		(29,201	)		2.99		(3,122	)		5.54		-		-		(99,483	)		2.45		(54,396	)		4.31		(87,138	)		4.64
Balance at March 31, 2023		1,169,957		$	3.17		2,143,034		$	3.27		1,205,193	$	3.63
Outstanding at June 30, 2023																925,649		$	3.37		2,040,253		$	3.35		1,002,079		$	3.62

	~~2023~~
Volatility		56.8	%
Risk-free interest rate		4.6	%
Correlation coefficient		41.7	%
Dividend yield		-	%

	Three Months Ended March 31,											Three Months Ended June 30,
(dollars in thousands)	2023		% of revenue			2022			% of revenue			2023			% of revenue			2022			% of revenue
Revenues	$	29,975				$	28,778					$	28,759					$	29,208
Gross profit		18,346		61.2	%		16,177			56.2	%		16,673			58.0	%		16,637			57.0	%
Sales and marketing expenses		5,978		19.9	%		6,687			23.2	%		6,178			21.5	%		6,587			22.6	%
General and administrative expenses		6,334		21.1	%		6,325			22.0	%		5,353			18.6	%		5,981			20.5	%
Research and development expenses		2,897		9.7	%		3,220			11.2	%		2,957			10.3	%		3,497			12.0	%
Amortization of intangible assets		1,388		4.6	%		1,466			5.1	%		1,389			4.8	%		1,454			5.0	%
Settlement of litigation, net		-		-			5,191			18.0	%
Litigation settlement													-			-			(4,880	)		-16.7	%
Unrealized loss on equity securities													1,581			5.5	%		-			-
Interest expense		974		3.2	%		384			1.3	%		941			3.3	%		515			1.8	%
Income tax expense (benefit)		585		2.0	%		(138	)		-0.5	%
Income tax (benefit) expense													(1,118	)		-3.9	%		986			3.4	%

10.1	~~Separation~~Employment Agreement between Jennifer Cote and ~~Release between~~ the Company ~~and Michael Rossi,~~ dated ~~January 18,~~June 19, 2023 (previously filed as an exhibit to the Company’s Current Report on Form 8-K on ~~January 19,~~June 20, 2023 and incorporated by reference thereto).
31.1	Certification of~~Interim~~ Chief Financial Officer of Harvard Bioscience, Inc., pursuant to Rules 13a-14(a) and 15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
31.2	Certification of Chief Executive Officer of Harvard Bioscience, Inc., pursuant to Rules 13a-14(a) and 15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
32.1*	Certification of ~~Interim~~ Chief Financial Officer of Harvard Bioscience, Inc., pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
32.2*	Certification of Chief Executive Officer of Harvard Bioscience, Inc., pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
101.INS	Inline XBRL Instance Document
101.SCH	Inline XBRL Taxonomy Extension Schema Document
101.CAL	Inline XBRL Taxonomy Extension Calculation Linkbase Document
101.DEF	Inline XBRL Taxonomy Extension Definition Linkbase Document
101.LAB	Inline XBRL Taxonomy Extension Labels Linkbase Document
101.PRE	Inline XBRL Taxonomy Extension Presentation Linkbase Document
104	Cover Page Interactive Data File (formatted in Inline XBRL and contained in Exhibit 101)

*	This certification shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, or otherwise subject to the liability of that section, nor shall it be deemed to be incorporated by reference into any filing under the Securities Act of 1933 or the Securities Exchange Act of 1934

	HARVARD BIOSCIENCE, INC.
Date: ~~April 26,~~August 8, 2023
	By:	/s/ JAMES GREEN
		James Green
		Chief Executive Officer


	By:	/s/ JENNIFER COTE
		Jennifer Cote
		~~Interim~~ Chief Financial Officer