Israel | 2834 | 81-3676773 |
(State or other jurisdiction of incorporation or organization) | (Primary Standard Industrial Classification Code Number) | (I.R.S. Employer Identification No.) |
Brent D. Fassett Jesse F. Schumaker Wilson Sonsini Goodrich & Rosati, P.C. 1881 9th Street, Suite 110 Boulder, CO 80023 (303) 256-5900 | David S. Glatt Ronen Bezalel Jonathan M. Nathan Matthew Rudolph Meitar | Law Offices 16 Abba Hillel Rd. Ramat Gan 5250608, Israel +972 (3) 610-3100 | Kaufman & Canoles, P.C. 919 Third Avenue Two James Center, 14th Floor | Ari Fried Gornitzky & Co. Vitania Tel Aviv Tower 20 HaHarash Street Tel Aviv, 6761310, Israel |
Large accelerated filer | ☐ | Accelerated filer | ☐ |
Non-accelerated filer | ☒ | Smaller reporting company | ☒ |
Emerging growth company | ☒ |
Per | Per Pre-Funded Unit | Total | |||
Public offering price | $ | $ | $ | ||
Underwriting discounts | $ | $ | $ | ||
Proceeds, before expenses, to us(2) | $ | $ | $ |
(1) | See “Underwriting” beginning on page 50 of this prospectus for a description of the compensation payable to the underwriter. |
(2) | The amount of proceeds, before expenses, to us does not give effect to the exercise of the Warrants. |
Aegis Capital Corp. |
Page | |
1 | |
7 | |
8 | |
12 | |
13 | |
14 | |
15 | |
16 | |
17 | |
18 | |
24 | |
31 | |
33 | |
• | A higher proportion of patients in the CM-101-treated group showed improvement in a physiologic measure of liver stiffness as compared to placebo (reduction of at least one grade of fibrosis score as assessed by the non-invasive elastography method known as FibroScan®). |
Up to | |
Pre-Funded Units | We are also potentially offering |
The | The underwriters will deliver American Depositary Shares As an ADS holder, you will not be treated as one of our shareholders and you will not have shareholder rights. The depositary, The Bank of New York Mellon, will be the holder of the ordinary shares underlying the ADSs. You will have the rights of an ADS holder or beneficial owner (as applicable) as provided in the deposit agreement among us, the depositary and holders and beneficial owners of ADSs from time to time. To better understand the terms of the ADSs, see “Description of Securities We Are Offering.” We also encourage you to read the deposit agreement, the form of which is filed as an exhibit to the registration statement of which this prospectus forms a part. You may turn in the ADSs to the depositary to cancel the ADSs and withdraw the ordinary shares. The depositary will charge you fees for any cancellation and withdrawal. |
Pre-Funded Warrants | The purchase price of each Pre-Funded Unit will equal the price per Unit, minus $0.001, and the exercise price of each Pre-Funded Warrant included in the Pre-Funded Unit will be $0.001 per ADS. The Pre-Funded Warrants offered hereby will be immediately exercisable and may be exercised on the date of issuance at any time until exercised in full. To better understand the terms of the Pre-Funded Warrants, you should carefully read the “Description of the Offered Securities” section of this prospectus. You should also read the form of the Pre-Funded Warrant, which is filed as an exhibit to the registration statement that includes this prospectus. |
Warrants | The Warrants offered hereby will be immediately exercisable on the date of issuance and will expire five years from the date of issuance. Each Warrant |
Over-allotment Option | We have granted the underwriter an option to purchase from us, at the public offering price, less the underwriting discounts, up to 986,842 additional ADSs and/or Pre-Funded Warrants, and/or up to 986,842 over-allotment Warrants, within 30 days after the closing of this offering to cover over-allotments, if any. The underwriter may exercise the over-allotment option with respect to ADSs only, Pre-Funded Warrants only, Warrants only, or any combination thereof. |
ADSs outstanding prior to this offering | 11,049,812 ADSs. |
ADSs outstanding after this offering | 17,628,759 ADSs (assuming full exercise of the Pre-Funded Warrants). |
Use of proceeds | We estimate the net proceeds from this offering will be approximately |
Risk factors | See “Risk Factors” beginning on page 8 for a discussion of factors you should carefully consider before deciding to invest in our securities. |
ADS depositary | The Bank of New York Mellon. |
Nasdaq Capital Market symbol | The ADSs are listed on Nasdaq under the symbol “CMMB.” We do not intend to list the Warrants on any securities exchange or nationally recognized trading system. |
● | 1,747,077 ADSs issuable upon the exercise of outstanding options to purchase ADSs, at a weighted average exercise price of $6.60 per ADS; | |
● | an aggregate of | |
● | 261,929 ADSs issuable upon the exercise of outstanding warrants to purchase ADSs at a weighted average exercise price of $17.35088 per ADS, which warrants are expected to remain outstanding at the consummation of this offering; and |
● | 6,578,947 ADSs issuable upon exercise of the Warrants issued in this offering. |
1. | Ablin, J. N., M. Entin-Meer, V. Aloush, S. Oren, O. Elkayam, J. George, and I. Barshack. 2010. 'Protective effect of eotaxin-2 inhibition in adjuvant-induced arthritis', Clin Exp Immunol, 161: 276-83. |
2. | Bhattacharyya, S., J. Wei, and J. Varga. 2011. 'Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities', Nat Rev Rheumatol, 8: 42-54. |
3. | Bocchino, V., G. Bertorelli, C. P. Bertrand, P. D. Ponath, W. Newman, C. Franco, A. Marruchella, S. Merlini, M. Del Donno, X. Zhuo, and D. Olivieri. 2002. 'Eotaxin and CCR3 are up-regulated in exacerbations of chronic bronchitis', Allergy, 57: 17-22. |
4. | Henderson, N. C., F. Rieder, and T. A. Wynn. 2020. 'Fibrosis: from mechanisms to medicines', Nature, 587: 555-66. |
5. | Jimenez, S. A., E. Hitraya, and J. Varga. 1996. 'Pathogenesis of scleroderma. Collagen', Rheum Dis Clin North Am, 22: 647-74. |
6. | Jose, P. J., D. A. Griffiths-Johnson, P. D. Collins, D. T. Walsh, R. Moqbel, N. F. Totty, O. Truong, J. J. Hsuan, and T. J. Williams. 1994. 'Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation', J Exp Med, 179: 881-7. |
7. | Karlsen, T. H., T. Folseraas, D. Thorburn, and M. Vesterhus. 2017. 'Primary sclerosing cholangitis - a comprehensive review', J Hepatol, 67: 1298-323. |
8. | Kitaura, M., T. Nakajima, T. Imai, S. Harada, C. Combadiere, H. L. Tiffany, P. M. Murphy, and O. Yoshie. 1996. 'Molecular cloning of human eotaxin, an eosinophil-selective CC chemokine, and identification of a specific eosinophil eotaxin receptor, CC chemokine receptor 3', J Biol Chem, 271: 7725-30. |
9. | Kohan, M., I. Puxeddu, R. Reich, F. Levi-Schaffer, and N. Berkman. 2010. 'Eotaxin-2/CCL24 and eotaxin-3/CCL26 exert differential profibrogenic effects on human lung fibroblasts', Ann Allergy Asthma Immunol, 104: 66-72. |
10. | Mor, A. , Afek, A. , Entin-Meer, M. , Keren, G. and George, J. 2013. 'Anti eotaxin-2 antibodies attenuate the initiation and progression of experimental atherosclerosis.', World Journal of Cardiovascular Diseases, 3: 339-46. |
11. | Mor, A., M. Segal Salto, A. Katav, N. Barashi, V. Edelshtein, M. Manetti, Y. Levi, J. George, and M. Matucci-Cerinic. 2019. 'Blockade of CCL24 with a monoclonal antibody ameliorates experimental dermal and pulmonary fibrosis', Ann Rheum Dis, 78: 1260-68. |
12. | Ponath, P. D., S. Qin, D. J. Ringler, I. Clark-Lewis, J. Wang, N. Kassam, H. Smith, X. Shi, J. A. Gonzalo, W. Newman, J. C. Gutierrez-Ramos, and C. R. Mackay. 1996. 'Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils', J Clin Invest, 97: 604-12. |
13. | Segal-Salto, M., N. Barashi, A. Katav, V. Edelshtein, A. Aharon, S. Hashmueli, J. George, Y. Maor, M. Pinzani, D. Haberman, A. Hall, S. Friedman, and A. Mor. 2020. 'A blocking monoclonal antibody to CCL24 alleviates liver fibrosis and inflammation in experimental models of liver damage', JHEP Rep, 2: 100064. |
14. | Wynn, T. A. 2008. 'Cellular and molecular mechanisms of fibrosis', J Pathol, 214: 199-210. |
As of December 31 , 2022 | As of December 31 , 2022 | |||||||||||||||
(in thousands)(unaudited) | (in thousands)(unaudited) | |||||||||||||||
Actual | As Adjusted | Actual | As Adjusted | |||||||||||||
Cash and cash equivalents and short-term bank deposits | $ | 39,970 | 53,530 | $ | 39,970 | 48,743 | ||||||||||
Shareholders’ equity | ||||||||||||||||
Ordinary Shares, no par value - Authorized: 650,000,000 ordinary shares as of December 31, 2022 | — | — | ||||||||||||||
Issued and outstanding: 232,636,700 ordinary shares issued and outstanding actual; 373,280,480 ordinary shares issued and outstanding as adjusted | ||||||||||||||||
Additional paid-in capital | 101,260 | 114,820 | 101,260 | 110,033 | ||||||||||||
Treasury stock at cost | (1,218 | ) | (1,218) | (1,218 | ) | (1,218 | ) | |||||||||
Accumulated deficit | (63,819 | ) | (63,819) | (63,819 | ) | (63,819 | ) | |||||||||
Total shareholders’ equity | $ | 36,223 | $ | 49,783 | $ | 36,223 | $ | 44,996 | ||||||||
Total liabilities and shareholders’ equity | $ | 43,063 | $ | 56,623 | $ | 43,063 | $ | 51,836 |
● | ||
● | an aggregate of | |
● | 261,929 ADSs issuable upon the exercise of outstanding warrants to purchase ADSs at a weighted average exercise price of $17.35088 per ADS, which warrants are expected to remain outstanding at the consummation of this offering; and | |
● |
Assumed offering price per ADS and accompanying Warrant | $ | 1.52 | ||||||
Net tangible book value per ADS as of December 31, 2022 | $ | 3.28 | ||||||
Net dilution in net tangible book value per ADS attributable to existing shareholders | $ | (0.73 | ) | $ | ||||
As adjusted net tangible book value per ADS after this offering | $ | 2.55 | ||||||
Net increase in net tangible book value per ADS to new investors in this offering | $ | 1.03 |
Assumed offering price per ADS and accompanying Warrant | $ | 1.97 | ||||||
Net tangible book value per ADS as of December 31, 2022 | $ | 3.28 | ||||||
Net dilution in net tangible book value per ADS attributable to existing shareholders | $ | (0.61 | ) | $ | ||||
As adjusted net tangible book value per ADS after this offering | $ | 2.67 | ||||||
Net increase in net tangible book value per ADS to new investors in this offering | $ | 0.70 |
● | ||
● | an aggregate of | |
● | 261,929 ADSs issuable upon the exercise of outstanding warrants to purchase ADSs at a weighted average exercise price of $17.35088 per ADS, which warrants are expected to remain outstanding at the consummation of this offering; and | |
● |
Year ended December 31, | ||||||||
2022 | 2021 | |||||||
Operating Expenses: | (in thousands) | |||||||
Research and development | $ | 16,977 | $ | 6,334 | ||||
General and administrative | 11,556 | 6,033 | ||||||
Total operating expenses | 28,533 | 12,367 | ||||||
Financing (income) expense, net | (353 | ) | 111 | |||||
Loss before taxes | 28,180 | 12,478 | ||||||
Taxes on income (benefit) | (534 | ) | - | |||||
Net loss | $ | 27,646 | $ | 12,478 |
Year ended December 31, | Increase/(decrease) | |||||||||||||||
2022 | 2021 | $ | % | |||||||||||||
(in thousands) | ||||||||||||||||
Net cash used in operating activities | $ | (20,370 | ) | $ | (12,374 | ) | $ | (7,996 | ) | 65 | % | |||||
Net cash provided by (used in) investing activities | 19,533 | (45,186 | ) | 64,719 | (143 | )% | ||||||||||
Net cash provided by (used in) financing activities | (808 | ) | 61,074 | (61,882 | ) | (101 | )% | |||||||||
Net increase (decrease) in cash, cash equivalents and restricted cash | $ | (1,645 | ) | $ | 3,514 | $ | (5,159 | ) | (147 | )% |
Name and Principal Position | Year | Salary (1) ($) | Bonus (2) ($) | Option Awards (3) ($) | All Other Compensation (4) ($) | Total ($) | ||||||||||||||||
Dale Pfost | 2021 | 182,557 | - | 300,000 | 22,868 | 505,425 | ||||||||||||||||
Chief Executive Officer and Chairman (5) | 2022 | 600,000 | 300,000 | 1,500,000 | 75,160 | 2,475,160 | ||||||||||||||||
Adi Mor | 2021 | 248,547 | 167,000 | 8,000 | 64,453 | 488,000 | ||||||||||||||||
Chief Scientific Officer, Director and Previous Chief Executive Officer (6) | 2022 | 298,470 | 120,000 | - | 16,926 | 435,396 | ||||||||||||||||
Donald Marvin | 2021 | 88,276 | - | 102,390 | 11,590 | 202,256 | ||||||||||||||||
Chief Financial Officer, Executive Vice President and Chief Operating Officer (7) | 2022 | 460,000 | 207,000 | 660,252 | 60,397 | 1,387,649 | ||||||||||||||||
Sigal Fattal | 2021 | 127,050 | 122,000 | 616,000 | 8,952 | 874,002 | ||||||||||||||||
Previous Interim Chief Financial Officer (8) |
Option awards | |||||||||||||
Name | Number of securities underlying unexercised options (#) exercisable | Number of securities underlying unexercised options (#) unexercsiable | Option exercise price ($) | Option expiration date | |||||||||
Dale Pfost, Chief Executive Officer and Chairman of the Board | 133,977 | 325,376 | (1) | 10.05 | October 25, 2031 | ||||||||
Adi Mor, Chief Scientific Officer, Director and Previous Chief Executive Officer | 131,698 | - | 1.49 | March 15, 2028 | |||||||||
Donald Marvin, Chief Financial Officer, Executive Vice President and Chief Operating Officer | 53,320 | 143,555 | (2) | 9.77 | November 8, 2031 |
Name | Fees earned or paid in cash ($) | Option awards ($) | Total ($) | |||||||||
Nissim Darvish | 47,000 | 76,000 | (1) | 123,000 | ||||||||
Jill Quigley | 23,000 | 15,000 | (2) | 38,000 | ||||||||
Alan Moses | 43,000 | 76,000 | (3) | 119,000 | ||||||||
Claude Nicaise | 47,000 | 76,000 | (4) | 123,000 | ||||||||
Neil Cohen | 47,000 | 76,000 | (5) | 123,000 |
Option awards | |||||||||||||
Name | Number of ADSs underlying unexercised options (#) exercisable | Number of ADSs underlying unexercised options (#) unexercsiable | Option exercise price ($) | Option expiration date | |||||||||
Nissim Darvish | 10,123 | - | 0.80 | October 27, 2026 | |||||||||
Nissim Darvish | 6,932 | 4,952 | 27.26 | April 19, 2031 | |||||||||
Nissim Darvish | - | 6,820 | 3.53 | March 7, 2032 | |||||||||
Alan Moses | 6,932 | 4,952 | 27.26 | April 19, 2031 | |||||||||
Alan Moses | - | 6,820 | 3.53 | March 7, 2032 | |||||||||
Claude Nicaise | 6,932 | 4,952 | 27.26 | April 19, 2031 | |||||||||
Claude Nicaise | - | 6,820 | 3.53 | March 7, 2032 | |||||||||
Neil Cohen | 515 | 173 | 13.20 | July 16, 2030 | |||||||||
Neil Cohen | 6,932 | 4,952 | 27.26 | April 19, 2031 | |||||||||
Neil Cohen | - | 6,820 | 3.53 | March 7, 2032 | |||||||||
Jill Quigley | 2,273 | 11,367 | 3.25 | June 16, 2032 |
• | each person who is known by us to own beneficially more than 5% of our ordinary shares; | |
• | each director; | |
• | each executive officer; and | |
• | all of our directors and executive officers collectively. |
NAME OF BENEFICIAL OWNER | Total Beneficial Ownership (ADSs) | Percentage of ADSs Beneficially Owned† | Total Beneficial Ownership (ADSs) | Percentage of ADSs Beneficially Owned† | ||||||||||||
5% and Greater Shareholders | ||||||||||||||||
OrbiMed Israel (1) | 2,270,091 | 20.5 | % | 2,270,091 | 20.5 | % | ||||||||||
The Centillion Fund(2) | 661,370 | 6.0 | % | 661,370 | 6.0 | % | ||||||||||
Rivendell Investments 2017-9(3) | 1,131,563 | 10.2 | % | 1,131,563 | 10.2 | % | ||||||||||
Kobi George(4) | 747,445 | 6.7 | % | 747,445 | 6.7 | % | ||||||||||
Apeiron Group(5) | 770,388 | 6.9 | % | 770,388 | 6.9 | % | ||||||||||
Directors and Executive Officers | ||||||||||||||||
Dale Pfost (6) | 165,187 | 1.4 | % | 174,757 | 1.6 | % | ||||||||||
Donald Marvin (7) | 71,726 | * | % | 75,828 | * | % | ||||||||||
Adi Mor (8) | 747,445 | 6.7 | % | 747,445 | 6.7 | % | ||||||||||
Neil Cohen (9) | 25,702 | * | 25,702 | * | ||||||||||||
Nissim Darvish (10) | 26,395 | * | 26,395 | * | ||||||||||||
Alan Moses (11) | 15,072 | * | 15,072 | * | ||||||||||||
Claude Nicaise (12) | 15,072 | * | 15,072 | * | ||||||||||||
Jill Quigley (13) | 3,788 | * | 3,788 | * | ||||||||||||
Matthew Frankel | - | - | - | - | ||||||||||||
All current executive officers and directors as a group (9 persons) | 1,070,387 | 9.29 | % | 1,084,059 | 9.40 | % |
(1) | Pursuant to a Schedule 13D/A filed with the SEC by OrbiMed Israel BioFund GP Limited Partnership (“OrbiMed BioFund”) and OrbiMed Israel GP Ltd. (“OrbiMed GP”, and together with OrbiMed BioFund, “OrbiMed Israel”) on January 5, 2023, such amount consists of (i) 2,241,274 ADSs and (ii) 28,817 ADSs issuable upon the exercise of warrants to purchase ADSs. OrbiMed GP, a company that acts as general partner of certain limited partnerships, is the general partner of OrbiMed BioFund, which is the general partner of OrbiMed Israel Partners Limited Partnership, which is the entity that holds the foregoing securities. The address of OrbiMed Israel is 89 Medinat HaYehudim St., Build E, 11th Floor, Herzliya 46766 Israel. |
(2) | The address of Centillion Fund, Inc. is 10 Manoel Street, Castries, Saint Lucia. |
(3) | Represents 1,108,509 ADSs, representing 22,170,180 ordinary shares, held by Rivendell Investments 2017-9 LLC, or Rivendell, as reported by Rivendell on Schedule 13G filed with the SEC on March 26, 2021, and 23,054 ADSs, representing 461,080 Ordinary Shares, issuable upon the exercise of warrants. Rivendell is the shareholder of record. Peter Thiel is the beneficial owner of Rivendell and has sole voting and investment power over the securities held by Rivendell. The address of Rivendell is 1209 Orange Street, Wilmington, Delaware 19801. |
(4) | Consists of (i) 257,247 ADSs owned directly by Dr. George, (ii) 324,775 ADSs owned by Dr. Adi Mor (Dr. George’s spouse), (iii) 33,725 options to purchase 33,725 ADSs issued directly to Dr. George, issuable upon the exercise of options, and (iv) 131,698 options to purchase 131,698 ADSs, issued to Dr. Mor, (Dr. George’s spouse), as reported by Dr. Adi Mor on Schedule 13D/A filed with the SEC on November 17, 2022. |
(5) | The Apeiron Group consists of (i) Apeiron SICAV Ltd. - Presight Capital Fund One, of which owns 438,993 ADSs, (ii) Apeiron Presight Capital Fund II, LP, of which owns 288,170 ADSs and 28,817 ADSs issuable upon the exercise of warrants and (iii) Apeiron Investment Group Ltd., of which owns 14,408 ADSs issuable upon the exercise of warrants. Each of Fabian Hansen and Christian Angermayer may be deemed to share voting and investment power with respect to the ADSs held by the Apeiron Group. |
(6) | Includes 2,500 ADSs and |
(7) | Includes 2,000 ADSs and |
(8) | Consists of (i) 324,775 ADSs owned directly by Dr. Mor, (ii) 257,247 ADSs owned by Dr. George, (Dr. Mor’s spouse), (iii) 131,698 ADSs issued to Dr. Mor, issuable upon the exercise of options within 60 days of the date hereof, and (iv) 33,725 options to purchase 33,725 ADSs issued to Dr. George, (Dr. Mor’s spouse) issuable upon the exercise of options within 60 days of the date hereof, as reported by Dr. Adi Mor on Schedule 13D/A filed with the SEC on November 17, 2022. |
(9) | Includes 10,000 ADSs, and 15,702 ADSs issuable upon the exercise of options within 60 days of the date hereof, as reported by Mr. Neil Cohen on Form 4 filed with the SEC on November 11, 2022. |
(10) | Includes 1,200 ADSs, and 25,195 ADSs issuable upon the exercise of options within 60 days of the date hereof, as reported by Dr. Nissim Darvish on Form 4 filed with the SEC on March 14, 2022. |
(11) | Represents 15,072 ADSs issuable upon the exercise of options within 60 days of the date hereof, as reported by Dr. Alan Moses on Form 4 filed with the SEC on March 9, 2022. |
(12) | Represents 15,072 ADSs issuable upon the exercise of options within 60 days of the date hereof, as reported by Dr. Claude Nicaise on Form 4 filed with the SEC on March 9, 2022. |
(13) | Represents 3,788 ADSs issuable upon the exercise of options within 60 days of the date hereof, as reported by Ms. Jill Quigley on Form 4 filed with the SEC on June 16, 2022. |
Persons depositing or withdrawing ordinary shares or ADS holders must pay | | For | |
$5.00 (or less) per 100 ADSs (or portion of 100 ADSs) | | Issuance of ADSs, including issuances resulting from a distribution of ordinary shares or rights or other property Cancellation of ADSs for the purpose of withdrawal, including if the deposit agreement terminates | |
$.05 (or less) per ADS | | Any cash distribution to ADS holders | |
A fee equivalent to the fee that would be payable if securities distributed to you had been ordinary shares and the ordinary shares had been deposited for issuance of ADSs | | Distribution of securities distributed to holders of deposited securities (including rights) that are distributed by the depositary to ADS holders | |
$.05 (or less) per ADS per calendar year | | Depositary services | |
Persons depositing or withdrawing ordinary shares or ADS holders must pay | | For | |
Registration or transfer fees | | Transfer and registration of ordinary shares on our share register to or from the name of the depositary or its agent when you deposit or withdraw ordinary shares | |
Expenses of the depositary | | Cable, telex and facsimile transmissions (when expressly provided in the deposit agreement) Converting foreign currency to U.S. dollars | |
Taxes and other governmental charges the depositary or the custodian has to pay on any ADSs or ordinary shares underlying ADSs, such as stock transfer taxes, stamp duty or withholding taxes | | As necessary | |
Any charges incurred by the depositary or its agents for servicing the deposited securities | | As necessary | |
Underwriter | | Number of ADSs Units | Number of | ||
Aegis Capital Corporation | | ||||
Total | | |
| ADS and Accompanying Warrant | Per Pre-Funded Unit | Total No Exercise | Total Full Exercise | |||||
Public offering price | $ | $ | $ | ||||||
Underwriting discounts | $ | $ | $ | ||||||
Proceeds, before expenses, to us | $ | $ | $ |
(a) | by an investment firm, bank or intermediary permitted to conduct such activities in Italy in accordance with Legislative Decree No. 58 of 24 February 1998 and Legislative Decree No. 385 of 1 September 1993 (the “Banking Act”); |
(b) | in compliance with Article 129 of the Banking Act and the implementing guidelines of the Bank of Italy; and |
(c) | in compliance with any other applicable laws and regulations and other possible requirements or limitations which may be imposed by Italian authorities. |
(a) | to legal entities which are authorized or regulated to operate in the financial markets or, if not so authorized or regulated, whose corporate purpose is solely to invest in securities; |
(b) | to any legal entity which has two or more of (1) an average of at least 250 employees during the last financial year; (2) a total balance sheet of more than €43,000,000 and (3) an annual net turnover of more than €50,000,000, as shown in its last annual or consolidated accounts; |
(c) | by the representative to fewer than 100 natural or legal persons (other than qualified investors as defined in the Prospectus Directive); or |
(d) | in any other circumstances falling within Article 3(2) of the Prospectus Directive, provided that no such offer of ADSs shall result in a requirement for the publication by the company or any underwriter of a prospectus pursuant to Article 3 of the Prospectus Directive. |
(a) | it has only communicated or caused to be communicated and will only communicate or cause to be communicated any invitation or inducement to engage in investment activity (within the meaning of section 21 of the Financial Services and Markets Act 2000 (the FSMA)) received by it in connection with the issue or sale of any ADSs in circumstances in which section 21(1) of the FSMA does not apply to the company; and |
(b) | it has complied with and will comply with all applicable provisions of the FSMA with respect to anything done by it in relation to the ADSs in, from or otherwise involving the United Kingdom. |
• | the judgment was rendered by a court which was, according to the laws of the state of the court, competent to render the judgment; | |
• | the obligation imposed by the judgment is enforceable according to the rules relating to the enforceability of judgments in Israel and the substance of the judgment is not contrary to public policy; and | |
• | the judgment is executory in the state in which it was given. |
• | the judgment was given in a state whose laws do not provide for the enforcement of judgments of Israeli courts (subject to exceptional cases); | |
• | the enforcement of the judgment is likely to prejudice the sovereignty or security of the State of Israel; | |
• | the judgment was obtained by fraud; | |
• | the opportunity given to the defendant to bring its arguments and evidence before the court was not reasonable in the opinion of the Israeli court; | |
• | the judgment was rendered by a court not competent to render it according to the laws of private international law as they apply in Israel; | |
• | the judgment is contradictory to another judgment that was given in the same matter between the same parties and that is still valid; or | |
• | at the time the action was brought in the foreign court, a lawsuit in the same matter and between the same parties was pending before a court or tribunal in Israel. |
• | The Registrant’s Annual Report on Form 10-K for the fiscal year ended December 31, |
• | The Company’s Current Reports on Form 8-K, as filed with the SEC on |
• | The description of our share capital, which is set forth in exhibit 4.1 of our Annual Report, and as may be further updated or amended in any amendment or report filed for such purpose; and | |
• | All other reports filed pursuant to Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), since the end of the fiscal year covered by the Annual Report. |
| |
|
ReportIndependent Registered Public Accounting FirmTo the Shareholders and Board of Directors,Chemomab Therapeutics Ltd.:Opinion on the Consolidated Financial StatementsWe have audited the accompanying consolidated balance sheets of Chemomab Therapeutics Ltd. (the Company) as of December 31, 2022 and 2021, the related consolidated statements of operations, changes in equity, and cash flows for each of the years in the two-year period ended December 31, 2022, and the related notes (collectively, the consolidated financial statements). In our opinion, the consolidated financial statements present fairly, in all material respects, the financial position of the Company as of December 31, 2022 and 2021, and the results of its operations and its cash flows for each of the years in the two-year period ended December 31, 2022, in conformity with U.S. generally accepted accounting principles.Basis for OpinionThese consolidated financial statements are the responsibility of the Company’s management. Our responsibility is to express an opinion on these consolidated financial statements based on our audits. We are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (PCAOB) and are required to be independent with respect to the Company in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the consolidated financial statements are free of material misstatement, whether due to error or fraud. The Company is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. As part of our audits, we are required to obtain an understanding of internal control over financial reporting but not for the purpose of expressing an opinion on the effectiveness of the Company’s internal control over financial reporting. Accordingly, we express no such opinion.Our audits included performing procedures to assess the risks of material misstatement of the consolidated financial statements, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the consolidated financial statements. Our audits also included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the consolidated financial statements. We believe that our audits provide a reasonable basis for our opinion.Somekh ChaikinMember Firm of KPMG InternationalWe have served as the Company’s auditor since 2015.Tel Aviv, IsraelFebruary 20, 2023© 2023 KPMG Somekh Chaikin, an Israeli partnership and a member firm of the KPMG global organization of independent member firms affiliated with KPMG International Limited, a private English company limited by guarantee. All rights reserved.F - 2
|
|
|
Note | December 31, 2022 | December 31, 2021 | |||||||||
Assets | |||||||||||
| |||||||||||
Current assets | |||||||||||
Cash and cash equivalents | 3 | 13,519 | 15,186 | ||||||||
Short-term bank deposit | 26,374 | 45,975 | |||||||||
Restricted cash | 77 | - | |||||||||
Other receivables and prepaid expenses | 4 | 1,766 | 1,527 | ||||||||
| |||||||||||
Total current assets | 41,736 | 62,688 | |||||||||
| |||||||||||
Non-current assets | |||||||||||
Restricted cash | - | 55 | |||||||||
Long-term prepaid expenses | 733 | 908 | |||||||||
Property and equipment, net | 5 | 367 | 357 | ||||||||
Operating lease right-of-use assets | 6 | 227 | 345 | ||||||||
| |||||||||||
Total non-current assets | 1,327 | 1,665 | |||||||||
| |||||||||||
Total assets | 43,063 | 64,353 | |||||||||
| |||||||||||
Current liabilities | |||||||||||
Trade payables | 1,688 | 1,336 | |||||||||
Accrued expenses | 3,378 | 555 | |||||||||
Employee and related expenses | 1,560 | 653 | |||||||||
Operating lease liabilities | 6 | 123 | 106 | ||||||||
| |||||||||||
Total current liabilities | 6,749 | 2,650 | |||||||||
| |||||||||||
Non-current liabilities | |||||||||||
Non-current operating lease liabilities | 6 | 91 | 237 | ||||||||
| |||||||||||
Total non-current liabilities | 91 | 237 | |||||||||
| |||||||||||
Commitments and contingent liabilities | 7 | ||||||||||
| |||||||||||
Total liabilities | 6,840 | 2,887 | |||||||||
| |||||||||||
Shareholders' equity | 8 | ||||||||||
| |||||||||||
Ordinary Shares no par value - Authorized: 650,000,000 shares as of December 31, 2022 and 2021; | |||||||||||
Issued and outstanding: 232,636,700 Ordinary shares at December 31, 2022 and 228,090,300 Ordinary shares at December 31, 2021 | - | - | |||||||||
Treasury share at cost (11,640,460 shares as of December 31, 2022) | (1,218 | ) | - | ||||||||
Additional paid-in capital | 101,260 | 97,639 | |||||||||
Accumulated deficit | (63,819 | ) | (36,173 | ) | |||||||
| |||||||||||
Total shareholders’ equity | 36,223 | 61,466 | |||||||||
Total liabilities and shareholders’ equity | 43,063 | 64,353 |
_____________________ _____________________
Chief Executive Officer Chief Financial Officer
Date of approval of the financial statements: February 20, 2023
The accompanying notes are an integral part of the consolidated financial statements.
F - 3
|
|
|
Note | December 31, 2022 | December 31, 2021 | |||||||||
Operating expenses | |||||||||||
| |||||||||||
Research and development | 9 | 16,977 | 6,334 | ||||||||
| |||||||||||
General and administrative | 10 | 11,556 | 6,033 | ||||||||
| |||||||||||
Total operating expenses | 28,533 | 12,367 | |||||||||
Financing (income) expenses, net | (353) | 111 | |||||||||
Loss before taxes | 28,180 | 12,478 | |||||||||
Taxes on income (benefit) | 11 | (534 | ) | - |
| ||||||
| |||||||||||
Net loss for the year | 27,646 | 12,478 | |||||||||
| |||||||||||
Basic and diluted loss per Ordinary Share | 13 | 0.121 | 0.060 | ||||||||
| |||||||||||
Weighted average number of Ordinary Shares outstanding, basic, and diluted | 13 | 227,589,288 | 207,468,650 |
The accompanying notes are an integral part of the consolidated financial statements.
F - 4
|
|
|
|
|
|
|
|
|
| ||||||||||||||||||||||
Ordinary Shares | Treasury | Additional | Accumulated Deficit | Total Shareholders' | ||||||||||||||||||||||||
Number | USD | Number | USD | USD | USD | USD | ||||||||||||||||||||||
Balance as of January 1, 2021 | 9,274,838 | - | - | - | 34,497 | (23,695 | ) | 10,802 | ||||||||||||||||||||
|
|
|
|
|
|
|
| |||||||||||||||||||||
Share-based compensation | - | - | - | - | 2,019 | - | 2,019 | |||||||||||||||||||||
Effect of reverse capitalization transaction | 152,299,702 | - | - | - | 2,476 | - | 2,476 | |||||||||||||||||||||
Issuance of shares and warrants, net of issuance costs | 66,381,520 | - | - | - | 58,637 | - | 58,637 | |||||||||||||||||||||
Exercise of options | 134,240 | - | - | - | 10 | - | 10 | |||||||||||||||||||||
Net loss for the year | - | - | - | - | - | (12,478 | ) | (12,478 | ) | |||||||||||||||||||
Balance as of December 31, 2021 | 228,090,300 | - | - | - | 97,639 | (36,173 | ) | 61,466 | ||||||||||||||||||||
Balance as of January 1, 2022 | 228,090,300 | - | - | - | 97,639 | (36,173 | ) | 61,466 | ||||||||||||||||||||
Share-based compensation | - | - | - | - | 3,211 | - | 3,211 | |||||||||||||||||||||
Issuance of shares, net of issuance costs | 2,576,400 | - | - | - | 267 | - | 267 | |||||||||||||||||||||
Exercise of options | 1,970,000 | - | - | - | 143 | - | 143 | |||||||||||||||||||||
Treasury share at cost | - | - | (11,640,460 | ) | (1,218 | ) | - | - | (1,218 | ) | ||||||||||||||||||
Net loss for the year | - | - | - | - | - | (27,646 | ) | (27,646 | ) | |||||||||||||||||||
Balance as of December 31, 2022 | 232,636,700 | - | (11,640,460 | ) | (1,218 | ) | 101,260 | (63,819 | ) | 36,223 |
F - 5
|
|
|
December 31, 2022 | December 31, 2021 | |||||||
Cash flows from operating activities | ||||||||
Net loss for the year | (27,646 | ) | (12,478 | ) | ||||
| ||||||||
Adjustments for operating activities: | ||||||||
Depreciation | 58 | 34 | ||||||
Share-based compensation | 3,211 | 2,019 | ||||||
Change in other receivables and prepaid expenses | (64 | ) | (2,058 | ) | ||||
Change in trade payables | 352 | 1,175 | ||||||
Change in accrued expenses | 2,823 |
| (1,279 | ) | ||||
Change in employees and related expenses | 907 | 215 | ||||||
Change in operating leases | (11 | ) | (2 | ) | ||||
Net cash used in operating activities | (20,370 | ) | (12,374 | ) | ||||
| ||||||||
Cash flows from investing activities | ||||||||
Investment in deposits | 19,601 | (45,951 | ) | |||||
Long-term lease deposit | - | 4 | ||||||
Sale of asset held for sale | - | 1,000 | ||||||
Purchase of property and equipment | (68 | ) | (239 | ) | ||||
Net cash provided by (used in) investing activities | 19,533 | (45,186 | ) | |||||
| ||||||||
Cash flows from financing activities | ||||||||
Cash acquired in Merger | - | 2,427 | ||||||
Exercise of options | 143 | 10 | ||||||
Treasury share at cost | (1,218 | ) | - | |||||
Issuance of shares and warrants, net of issuance costs | 267 | 58,637 | ||||||
Net cash provided by (used in) financing activities | (808 | ) | 61,074 | |||||
| ||||||||
Change in cash, cash equivalents and restricted cash | (1,645 | ) | 3,514 |
| ||||
| ||||||||
Cash, cash equivalents and restricted cash at beginning of the year | 15,241 | 11,727 | ||||||
| ||||||||
Cash, cash equivalents and restricted cash at end of the year | 13,596 | 15,241 | ||||||
| ||||||||
Supplementary cash flows information: | ||||||||
A. Cash paid and received during the year for: | ||||||||
Income taxes received | 351 | - | ||||||
Income taxes paid | (5 | ) | - | |||||
Interest received | 972 | 74 | ||||||
B. Significant non- cash transaction: | ||||||||
Right-of-use asset recognized with corresponding lease liability | 17 | 345 | ||||||
Liabilities assumed, net of non-cash assets received in Merger | - | 49 |
The accompanying notes are an integral part of the consolidated financial statements.
F - 6
|
|
Note 1 - General
1.Chemomab Therapeutics Ltd. (hereinafter - "the Company") is an Israeli-based company incorporated under the laws of the State of Israel in September 2011. The Company’s registered office is located in Kiryat Atidim, Tel Aviv, Israel.
The Company is a clinical-stage biotech company discovering and developing innovative therapeutics for conditions with high-unmet medical need that involve inflammation and fibrosis.
The wholly owned subsidiaries of the Company are: Chemomab Ltd. ("Chemomab"), Chemomab Therapeutics Israel Ltd. and Chemomab Therapeutics Inc.
2.The Company currently has no products approved for sale. The Company’s operations are funded primarily by its Shareholders. The Company has incurred operating losses in each year since its inception and does not expect to generate significant revenue unless and until it obtains marketing approval for its products. Continuation of the Company’s development programs depend on its future ability to raise sources of financing.
3.Since January 2020, the COVID-19 pandemic has dramatically expanded into a worldwide pandemic, creating macro-economic uncertainty and disruption in the business and financial markets. Many countries around the world, including Israel, had taken measures designated to limit the continued spread of the COVID-19 pandemic, including the closure of workplaces, restricting travel, prohibiting assembling, closing international borders and quarantining populated areas. The Company's clinical trial sites have been affected by the COVID-19 pandemic, and as a result, commencement of the enrollment in our clinical trials of CM-101 in PSC was delayed, and the enrollment rate has been, and is still, affected as well. As a result, The Company expanded its patient recruiting efforts to additional territories. In addition, after enrollment in these trials, patients might still drop out because of possible COVID-19 implications. Based on management’s assessment, the extent to which the lingering effects of the COVID-19 pandemic will further impact the Company's operations will depend on future developments. These developments, which are highly uncertain and cannot be predicted with confidence,including the duration and severity of the impact on patient enrollment following the attenuation of the outbreak The Company is carefully monitoring the impacts arising from the COVID-19 pandemic and will adjust activities accordingly.
4.On December 14, 2020, the Company (formerly known as Anchiano Therapeutics Ltd.) entered into an Agreement and Plan of Merger (the "Merger" and “Merger Agreement”) with Chemomab Ltd., an Israeli limited company, and CMB Acquisition Ltd., an Israeli limited company and a wholly owned subsidiary of the Company (“Merger Sub”). On March 16, 2021, (the “Effective Time”), the Company consummated the Merger pursuant to the Merger Agreement Pursuant to the terms of the Merger Agreement, Merger Sub merged with and into Chemomab Ltd., with Chemomab Ltd. surviving the Merger as the Company's wholly owned subsidiary. In connection with the Merger, on March 16, 2021, the Company changed its name from “Anchiano Therapeutics Ltd.” To “Chemomab Therapeutics Ltd" and the business conducted by Chemomab Ltd. became primarily the business conducted by the Company.
At the Effective Time(a) each Chemomab Ltd. ordinary share outstanding immediately prior to the Effective Time was converted solely into number of American Depository Shares equal to the exchange ratio described in the Merger Agreement, and each outstanding Chemomab Ltd. option was assumed by the Company, based on the same exchange ratio.
F - 7
|
|
Note 1 - General (cont’d)
4. (cont'd)
For accounting purposes, Chemomab Ltd. is considered to have acquired the Company based upon the terms of the Merger as well as other factors. The Merger has been accounted for as an asset acquisition (reverse recapitalization transaction) rather than a business combination, as the assets acquired, and the liabilities assumed by Chemomab Ltd. do not meet the definition of a business under U.S. GAAP. The net assets acquired in connection with the Merger were recorded at their estimated acquisition date fair market value as of March 16, 2021, the date of completion of the Merger.
The exchange ratio was calculated by a formula that was determined through arms-length negotiations between the Company and Chemomab Ltd. The combined Company assumed all of the outstanding options of Chemomab Ltd., vested and not vested, under the Chemomab Share Incentive Plan (the “2015 Plan”), with such options representing the right to purchase a number of ADSs equal to approximately 12.86 multiplied by the number of Chemomab Ltd. ordinary shares previously represented by such options.
The following table summarizes the net assets acquired based on their estimated fair values as of March 16, 2021, immediately prior to completion of the Merger (in USD thousands):
|
| |||
|
| |||
|
| |||
|
|
| ||
|
|
F - 8
|
|
Note 2 - Summary of Significant Accounting Policies
A.Basis of Preparation
The financial statements have been prepared in accordance with generally accepted accounting principles in the United States of America (“U.S GAAP”).
B.Use of estimates
The preparation of financial statements in conformity with U.S. GAAP requires management to make estimates, judgments and assumptions that affect the amounts reported in the financial statements and accompanying notes. Actual results could differ from those estimates.
C.Foreign currency
The currency of the primary economic environment in which the operations of the Company are conducted is the U.S. dollar (“dollar” or “$”), thus; the dollar is the functional currency of the Company.
The transactions and balances of the Company denominated in U.S. dollars are presented at their original amounts as the U.S. dollar is the currency of the primary economic environment in which the Company has operated and expects to continue to operate in the foreseeable future.
Monetary assets and liabilities denominated in a non-U.S. dollar currency are translated using the current exchange rate and nonmonetary assets and liabilities and capital accounts denominated in a non-U.S. dollar currency are translated using historical exchange rates.
Statements of operations accounts denominated in a non-U.S. dollar currency are translated using the exchange rates in effect on the transaction dates, except for depreciation, which is translated using historical exchange rate.
D.Cash and cash equivalents
Cash equivalents are short-term highly liquid investments that are readily convertible to cash with original maturities of three months or less at the date acquired.
E.Restricted cash
Restricted cash is primarily invested in highly liquid deposits. These deposits were used to secure office rent payments.
F.Property and equipment
Property and equipment are stated at cost less accumulated depreciation. Maintenance and repair expenses are charged to operation as incurred. Depreciation is calculated on the straight-line method based on the estimated useful lives of the assets and commences once the assets are ready for their intended use.
Annual rates at depreciation are as follows:
| ||||
|
| |||
|
| |||
|
| |||
|
F - 9
|
|
Note 2 - Summary of Significant Accounting Policies (cont’d)
G.Impairment of long-lived assets
The Company’s property and equipment are reviewed for impairment in accordance with ASC 360, “Property and Equipment”, whenever events or changes in circumstances indicate that the carrying amount of an asset may not be recoverable. Recoverability of assets to be held and used is measured by a comparison of the carrying amount of an asset to the future undiscounted cash flows expected to be generated by the assets. If such assets are considered to be impaired, the impairment to be recognized is measured by the amount by which the carrying amount of the assets exceeds the fair value of the assets. Assets to be disposed of are reported at the lower of the carrying amount or fair value less selling costs. During the periods ended December 31, 2022 and 2021, no impairment losses have been recorded.
H.Research and Development
Research and development costs are charged to operations as incurred. Most of the research and development expenses are for subcontractors and wages.
I.Income taxes
The Company accounts for income taxes under the asset and liability method, which requires the recognition of deferred tax assets and liabilities for the expected future tax consequences of events that have been included in the financial statements. Under this method, deferred tax assets and liabilities are determined on the basis of the differences between the financial statements and tax basis of assets and liabilities using enacted tax rates in effect for the year in which the differences are expected to reverse. The effect of a change in tax rates on deferred tax assets and liabilities is recognized in income in the period that includes the enactment date.
The Company recognizes net deferred tax assets to the extent that the Company believes these assets are more likely than not to be realized. In making such a determination, management considers all available positive and negative evidence, including future reversals of existing taxable temporary differences, projected future taxable income, tax-planning strategies, and results of recent operations. If management determines that the Company would be able to realize its deferred tax assets in the future in excess of their net recorded amount, management would make an adjustment to the deferred tax asset valuation allowance, which would reduce the income taxes expense.
The Company recognizes the effect of income tax positions only if those positions are more likely than not of being sustained. Recognized income tax positions are measured at the largest amount that is greater than 50 percent likely of being realized.
J.Fair value of financial instruments
ASC 820, Fair Value Measurements and Disclosures, relating to fair value measurements, defines fair value and established a framework for measuring fair value. The ASC 820 fair value hierarchy distinguishes between market participant assumptions developed based on market data obtained from sources independent of the reporting entity and the reporting entity’s own assumptions about market participant assumptions developed based on the best information available in the circumstances. ASC 820 defines fair value as the price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants at the measurement date, essentially an exit price.
F - 10
|
|
Note 2 - Summary of Significant Accounting Policies (cont’d)
J.Fair value of financial instruments (cont’d)
In addition, the fair value of assets and liabilities should include consideration of non-performance risk, which for the liabilities described below includes the Company’s own credit risk.
As a basis for considering such assumptions, ASC 820 establishes a three-tier value hierarchy, which prioritizes the inputs used in the valuation methodologies in measuring fair value:
Level 1: Quoted prices (unadjusted) in active markets that are accessible at the measurement date for assets or liabilities. The fair value hierarchy gives the highest priority to Level 1 inputs.
Level 2: Observable prices that are based on inputs not quoted on active markets, but corroborated by market data or active market data of similar or identical assets or liabilities.
Level 3: Unobservable inputs are used when little or no market data is available. The fair value hierarchy gives the lowest priority to Level 3 inputs.
The carrying amounts of cash and cash equivalents trade payables, other receivables and accrued expenses approximate their fair value due to the short-term maturity of such instruments. The fair value of long-term restricted deposits and restricted cash also approximates their carrying value, since they bear interest at rates close to the prevailing market rates. None of the Company’s non- financial assets or liabilities are recorded at fair value on a non-recurring basis. No transfers between levels have occurred during the periods presented.
K.Share-based compensation
The Company accounts for share-based compensation as an expense in the financial statements based on ASC 718. All awards are equity classified and therefore such costs are measured at the grant date fair value of the award and graded vesting attribution approach to recognize compensation cost over the vesting period. The Company recognizes compensation cost for an award with only service conditions that has a graded vesting schedule on a straight-line basis over the requisite service period for the entire award, provided that the cumulative amount of compensation cost recognized at any date at least equals the portion of the grant-date value of such award that is vested at that date.
The fair value for the Company’s stock options granted to employees, consultants and directors was estimated using Black-Scholes option-pricing model at the grant date, using the inputs detailed in Note 8(C).
The Company has historically not paid dividends and has no foreseeable plans to pay dividends.
L.Government-sponsored research and development
Chemomab records grants received from the office of the Israel Innovation Authority (the “IIA”) as a liability, if it is probable that the Chemomab will have to repay the grants received. If it is not probable that the grants will be repaid, Chemomab records the grants as a reduction to research and development expenses.
F - 11
|
|
Note 2 - Summary of Significant Accounting Policies (cont’d)
M.Severance pay
Pursuant to Section 14 of the Severance Compensation Law, 1963 ("Section 14"), all employees of the Company are entitled only to monthly deposits, at a rate of 8.33% of their monthly salary, made on their behalf with insurance companies. Upon release of the policy to the employee, no additional liability exists between the parties regarding the matter of severance pay and no additional payments shall be made by the Company to the employee. This plan has been accounted for as a defined contribution plan. Severance costs amounted to approximately $142 thousand and $116 thousand for the year ended December 31, 2022 and 2021, respectively.
N.Concentrations of credit risk:
Financial instruments that potentially subject the Company to concentrations of credit risk consist principally of cash and cash equivalents.
Cash and cash equivalents and short- term deposits are invested in banks. Management believes that the financial institutions that hold the Company’s investments are financially sound and, accordingly, minimal credit risk exists with respect to these investments.
The Company have no off-balance-sheet concentration of credit risk such as foreign exchange contracts, option contracts or other foreign hedging arrangements.
O.Leases
Under Topic 842, the Company determines if an arrangement is a lease at inception. Right-of-use (ROU) assets and lease liabilities are recognized at commencement date based on the present value of remaining lease payments over the lease term. For this purpose, the Company considers only payments that are fixed and determinable at the time of commencement. As most of the Company's leases do not provide an implicit rate, the Company uses its incremental borrowing rate based on the information available at commencement date in determining the present value of lease payments. The Company's incremental borrowing rate is a hypothetical rate based on its understanding of what its credit rating would be 5% and 5.2% in 2022 and 2021, respectively. The Company's lease terms may include options to extend or terminate the lease when it is reasonably certain that the Company will exercise such options. When determining the probability of exercising such options, the Company considers contract-based, asset-based, entity-based, and market-based factors. For leases agreements, the Company has elected the practical expedient to account for the lease and non-lease maintenance components as a single lease component. Therefore, for those leases, the lease payments used to measure the lease liability include all the fixed consideration in the contract. The Company's lease agreements generally do not contain any residual value guarantees or restrictive covenants.
For operating leases, the ROU asset is subsequently measured throughout the lease term at the carrying amount of the lease liability, plus initial direct costs, plus (minus) any prepaid (accrued) lease payments, less the unamortized balance of lease incentives received. Lease expense for lease payments is recognized on a straight-line basis over the lease term.
ROU assets for operating leases are periodically reduced by impairment losses. The Company uses the long-lived assets impairment guidance in ASC Subtopic 360-10, Property, Plant, and Equipment – Overall, to determine whether an ROU asset is impaired, and if so, the amount of the impairment loss to recognize. See Note 2(G).
F - 12
|
|
Note 2 - Summary of Significant Accounting Policies (cont’d)
P.Principles of consolidation
The consolidated financial statements include the accounts of the Company and its Subsidiaries. Intercompany balances and transactions have been eliminated in consolidation.
Q.Earnings per ordinary share
Basic earnings per ordinary share is calculated using only weighted average ordinary shares outstanding. Diluted earnings per share, if relevant, gives effect to dilutive potential ordinary shares outstanding during the year. Such dilutive shares consist of incremental shares, using the treasury stock method, from the assumed exercise of share options.
Note 3 - Cash and Cash Equivalents
December 31, | December 31, | |||||||
2022 | 2021 | |||||||
USD thousands | USD thousands | |||||||
In USD | 10,663 | 10,720 | ||||||
In NIS | 2,756 | 1,116 | ||||||
In other currencies | 100 | 3,350 | ||||||
| ||||||||
13,519 | 15,186 |
Note 4 - Other Receivables and Prepaid Expenses
December 31, | December 31, | |||||||
2022 | 2021 | |||||||
USD thousands | USD thousands | |||||||
Government institutions | 459 | 179 | ||||||
Prepaid expenses | 1,307 | 1,348 | ||||||
| ||||||||
1,766 | 1,527 |
F - 13
|
|
Note 5 - Property and Equipment, Net
December 31, | December 31, | |||||||
2022 | 2021 | |||||||
USD thousands | USD thousands | |||||||
Cost: | ||||||||
Computers | 70 | 43 | ||||||
Furniture and equipment | 33 | 27 | ||||||
Laboratory equipment | 399 | 364 | ||||||
Website development | 14 | 14 | ||||||
Leasehold improvements | 16 | 16 | ||||||
| 532 | 464 | ||||||
Less - accumulated depreciation | (165 | ) | (107 | ) | ||||
| ||||||||
| 367 | 357 |
Note 6 - Leases
On May 10, 2020, Chemomab entered into an office and lab space lease agreement (hereinafter – “The Agreement” .(According to the Agreement, Chemomab rented a space in Atidim Park, Tel-Aviv for a period of three years, through May 2023. Chemomab was granted an option to extend the lease term by additional three years.
On October 24, 2021, Chemomab signed an amendment to the Agreement ("The Amendment"). According to the Amendment, On December 12, 2021 Chemomab returned the previous office and lab space to the property owner and rented a larger space in Atidim Park Tel-Aviv, for a term of 3 years, through October 2024. In addition, Chemomab was granted an option to extend the lease term by additional three years. The annual rent and management fees are approximately $122 thousand. Pursuant to the Amendment, the bank guarantee issued in 2020 was canceled and a substitute bank guarantee of approximately $77 thousand was issued to the property owner during 2022.
The above operating leases are included in “Operating lease right-of-use assets” on the Company’s Consolidated Balance sheets as of December 31, 2022 and 2021 and represent the Company’s right to use the underlying asset for the lease term. The Company’s obligations to pay lease payments are included in the current liabilities as “Operating lease liabilities” and in the non-current liabilities as “Non-current operating lease liabilities” on the Company’s Consolidated Balance sheets as of December 31, 2022 and 2021. Based on the present value of the lease payments for the remaining lease term of the Company’s existing lease agreement, the Company recognized operating right-of-use assets and operating lease liabilities of approximately $345 thousand on December 12, 2021.
During the years ended December 31, 2022 and 2021, the Company recognized an increase in right of use assets of $17 thousand and $345 thousand, respectively.
As of December 31, 2022, and 2021 operating right-of-use asset was $227 thousand and $345 thousand, respectively. The operating lease liabilities were $214 thousand and $343 thousand, respectively.
F - 14
|
|
Note 6 - Leases (cont’d)
As most of the Chemomab’s leases do not provide an implicit rate, Chemomab uses its incremental borrowing rate based on the information available at the commencement date of each lease in determining the present value of lease payments. Chemomab’s incremental borrowing rate is a hypothetical rate based on its estimation of what its credit rating would be the rate was 5% in 2022 and 5.2% in 2021.
Maturities of lease liabilities under noncancellable leases as of December 31, 2022, are as follows: (in thousands):
2023 | 126 | |||
2024 | 93 | |||
Total future minimum lease payments | 219 | |||
Less imputed interest: | (5 | ) | ||
Present value of operating lease liabilities | 214 |
Note 7 - Commitments and Contingent Liabilities
A.Exclusive License Agreement (hereinafter- “the License Agreement”)
In December 2011, Chemomab entered into a License Agreement with the Medical Research, Infrastructure, Health Services Fund of the Tel-Aviv Souraski Medical Center (“Fund”), pursuant to which it was granted with an exclusive license to certain inventions (as defined in the License Agreement) including patents, knowhow and products and the right to sublicense to third parties the rights granted, pursuant to and subject to certain terms and limitation fully set in the License Agreement.
Chemomab has agreed to pay the Fund a non-refundable and non-creditable sublicense fees as a percentage of all Attributed Income (as such term defined in the License Agreement), and shall further pay the Fund royalties from sales made by sublicensee;
(i)Royalties in percentage of the Net sales or Service Income (as defined in the License Agreement), subject to certain additional terms set forth therein.
In addition, with respect to each Licensed Product (as defined therein), Chemomab has agreed to pay the Fund the following non-refundable, non-creditable amounts:
(a)$100 thousand upon submission of a New Drug Application (“NDA”), Biological License Application (“BLA”) or equivalent for each Licensed Product to the United States Food and Drug Administration (“FDA”), $100 thousand upon submission of similar application for each Licensed Product to an equivalent foreign regulatory agency in Europe and one hundred thousand dollars upon submission of similar application for each Licensed Product to an equivalent foreign regulatory agency in Asia. Payment in the aggregate shall not be more than $300 thousand per each Licensed Product, provided that for each jurisdiction, payment shall be made only once;
(b)$200 thousand upon the grant of FDA or equivalent agency marketing approval in Europe and/or Asia for each Licensed Product. Payment in the aggregate shall not be more than $600 thousand per each Licensed Product, provided that for each jurisdiction, payment shall be made only once.
As of December 31, 2022 no payments were made to the Fund.
F - 15
|
|
Note 7 - Commitments and Contingent Liabilities (cont’d)
A.Exclusive License Agreement (hereinafter- “the License Agreement”) (cont’d)
In addition to the payments described above, upon the occurrence of either (i) closing of a public offering of the ordinary shares of Chemomab; or (ii) a Change of Control Transaction, Chemomab shall pay the Fund a cash payment equal to one percent (1%) of the proceeds raised by Chemomab in its initial public offering, or 1% of the consideration received by Chemomab or its shareholders at the closing of a Change of Control Transaction (after deduction of amounts paid as liquidation preference to the shareholders of Chemomab on account of their investment in Chemomab, if any), but in any event not more than $3,000 thousand.
Chemomab partially financed its research and development expenditures under programs sponsored by the Israel Innovation Authority (“IIA”) for the support of certain research and development activities conducted in Israel.
In return for the IIA’s participation, Chemomab is committed to pay royalties at rate of 3% of sales of the developed product (linked to U.S. dollar), up to 100% of the amount of grants received (100% plus interest at LIBOR). In addition, the IIA may impose certain conditions to transfer technology or development out of Israel.
Chemomab did not receive any grants from the IIA in the years ended December 31, 2022, and 2021.
Since Chemomab ’s incorporation through December 31, 2022 Chemomab received $1,227 thousand from the IIA, which were recognized as a reduction of research and development expenses.
As of December 31, 2022, Chemomab has no commitment for royalties payable.
B.In June 2015, Chemomab entered into a license agreement with subcontractor (“the Subcontractor”), under which the Subcontractor granted to Chemomab certain licenses to use proprietary rights of the subcontractor, materials and know how in the techniques and use of the same, for purposes of research and development of Chemomab 's product CM-101, as well as commercialization thereof. Further to the agreement, the Subcontractor also provides manufacturing services of intermediates and active pharmaceutical ingredients. According to the related manufacturing agreement, the manufacturing of the product is carried out by the Subcontractor in accordance with Chemomab's specifications and timeline. From time to time, Chemomab and the Subcontractor have been signing additional agreements for additional manufacturing and final process lock of the product for clinical use Under the agreement, Chemomab is also obligated to pay the Subcontractor royalties determined as a percentage of net sales of each licensee product.
During 2022 and 2021, Chemomab recorded expenses related to the above agreements in the amounts of $5,222 thousand and $2,590 thousand, respectively. The expenses were recorded under research and development expenses.
F - 16
|
|
Note 7 - Commitments and Contingent Liabilities (cont’d)
C.As of December 31, 2022, the bank imposed restriction on a bank deposit in the amount of $77 thousand for the purpose of secure lease payments under an office lease agreement.
D.During 2022, the Israeli tax authority ("ITA”) notified the Company that it had initiated a routine VAT audit to include tax years 2017 through 2022. The ITA raised several claims, mainly in respect with the recoverability of VAT with respect to Merger Agreement related expenses and the classification of the Company as a holding company. On July 2022, the ITA proposed a settlement, which the Company rejected. As a result, the ITA issued assessments in the aggregate amount of $1,046 thousand. The Company filed an appeal against the ITA’s assessments. The Company has recorded an appropriate provision which considers inherent uncertainty of these matters and the judicial process. Therefore, the outcome may differ from the estimated liability recorded by the Company during the period.
Note 8 - Share Capital
A.Right attached to shares
Ordinary shares
All of the issued and outstanding ordinary shares of the Company are duly authorized, validly issued, fully paid and non-assessable. The ordinary shares are not redeemable, and each ordinary share is entitled to one vote. The holders of the ordinary shares have the right to vote and participate in shareholders' meetings, the right to receive profits, and the right to participate in the accumulated earnings when the Company is dissolved.
1.Voting
The holders of ordinary shares are entitled to vote on all matters submitted to shareholders for a vote.
2.Dividends
The holders of the ordinary shares are entitled to receive dividends, when and as declared by the Board of Directors, and out of funds legally available.
Since its inception, the Company has not declared any dividends.
F - 17
|
|
Note 8 - Share Capital (cont’d)
B.Financing rounds
1.In connection with the Merger, on March 15, 2021, the Company entered into Securities Purchase Agreements with certain purchasers, pursuant to which the Company agreed to sell approximately $45.5 million of its American Depositary Shares (ADSs) in a private placement transaction, (or "The Private Placement"). The Private Placement closed on March 22, 2021, at which time the Company sold to the purchasers 2,619,270 ADSs together with warrants to purchase up to 261,929 ADSs at an exercise price of $17.35 per ADS. The warrants will expire five years from the date of issuance, and if exercised in full, will provide to the Company proceeds of approximately $4.5 million. 20 Ordinary Shares are equal to 1One American Depositary Share (ADS).
2.On April 30, 2021, the Company entered into an At the Market Offering Agreement (the "ATM Agreement") with Cantor Fitzgerald & Co., ("Cantor"). Accordingand One Warrant to the ATM Agreement, the Company may offer and sell, from time to time, its ADSs having an aggregate offering price of up to $75 million through Cantor or the ATM Agreement. From April 30, 2021, through December 31, 2022, the Company issued 699,806 ADSs at an average price of $22.75 per ADS under the ATM Agreement, resulting in gross proceeds of $15,917 thousand.
3.On April 25, 2022, the Company filed a prospectus supplement with the SEC for the issuance and sale of up to $18,125,000 of its ADSs in connection with the reactivation of the ATM Facility and pursuant to General Instruction I.B.6 of Form S-3, which, subject to certain exceptions, limits the amount of securities the Company is able to offer and sell under such registration statement to one-third of our unaffiliated public float. During the year ended December 31, 2022, the Company issued 130,505 ADSs at an average price of $2.11 per ADS under the ATM Agreement, resulting in gross proceeds of $275 thousand.
4.On September 19, 2022, the Company entered into a share purchase agreement (the “Repurchase Arrangement”) with Dr. Adi Mor, co-founder of Chemomab Ltd., Chief Scientific Officer and a director of the Company and Professor Kobi George, co-founder of Chemomab Ltd. (together with Dr. Adi Mor, the “Co-Founders”), whereby the Company agreed, subject to the requisite court approval required under Section 303(a) of the Israeli Companies Law, 5759-1999 (the “Companies Law”), which the Company received on November 14, 2022, to repurchase up to 582,023 ADSs owned by the Co-Founders, for consideration not to exceed an aggregate amount of $2,500,000, depending on the market price of the ADSs at the time of any repurchase. Accordingly, on November 16, 2022, the company repurchased the entire amount of 582,023 ADSs from the Co-Founders at a weighted average price of $2.0848 and for total consideration of approximately $1,218 thousand.
The Company accounted for the repurchased shares as treasury share in accordance with ASC 505-30, "Treasury Stock".
F - 18
|
|
Note 8 - Share Capital (cont’d)
C.Share-based compensation
(1)Share-based compensation plan:
The Company maintains (i) the 2011 Share Option Plan (the “2011 Plan”), (ii) the 2017 Equity-Based Incentive Plan (the “2017 Plan”) and (iii) the Chemomab 2015 Share Incentive Plan (the “2015 Plan”), which was assumed by the Company from Chemomab upon the effectiveness of the Merger. At that time, outstanding options under the 2015 Plan became exercisable for such number of ADSs of the Company as was determined based on the exchange ratio in the Merger Agreement, with a reciprocal adjustment to exercise price.
As of December 31, 2022, a total of 28,443,060 of our Ordinary Shares (equal to 1,422,153 of ADSs) were reserved for issuance under the 2015 Plan, of which 3,445,520 Ordinary Shares (equal to 172,276 ADSs) had been issued pursuant to previous exercises options, and 23,460,740 Ordinary Shares (equal to 1,173,037 ADSs) were issuable under outstanding options. Of such outstanding options, options to purchase 12,400,720 Ordinary Shares (equal to 620,036 ADSs) had vested and were exercisable as of that date, with a weighted average exercise price of $0.30 per Ordinary Share (or $5.96 per ADS). During the year ended December 31, 2022, options to purchase 1,240,120 Ordinary Shares (equal to 62,006 ADS) were canceled.
As of December 31, 2022, a total of 12,511,620 of our Ordinary Shares (equal to 625,581 ADSs) were reserved for issuance under the 2017 Plan, of which 11,730,800 Ordinary Shares (equal to 586,540 ADSs) were issuable under outstanding options. Of such outstanding options, options to purchase 427,540 Ordinary Shares (equal to 21,377 ADSs) had vested and were exercisable as of that date, with a weighted average exercise price of $0.35 per Ordinary Share (or $6.98 per ADS). During the year ended December 31, 2022 no options were canceled.
(2)The expenses that were recognized in the consolidated statements of operations for services received from employees and service providers are as follows:
Year ended | Year ended | |||||||
December 31, | December 31, | |||||||
2022 | 2021 | |||||||
USD thousands | USD thousands | |||||||
Research and development | 448 | 137 | ||||||
General and administrative | 2,763 | 1,882 | ||||||
| ||||||||
Total share-based compensation expenses | 3,211 | 2,019 |
F - 19
|
|
Note 8 -Depositary Share Capital (cont’d)
(3)The number and weighted average exercise price of options are as follows:
Weighted average exercise price | Number of options | Weighted average remaining contractual life (in years) | Weighted average exercise price | Number of options | Weighted average remaining contractual life (in years) | |||||||||||||||||||
2022 | 2022 | 2022 | 2021 | 2021 | 2021 | |||||||||||||||||||
Outstanding at January 1 | 0.38 | 27,003,260 | 8.12 | 0.07 | 10,455,580 | 7.8 | ||||||||||||||||||
Acquired in Merger | - | - | - | 609,535 | - | |||||||||||||||||||
Exercised | 0.07 | (1,970,000 | ) | - | 0.08 | (134,220 | ) | - | ||||||||||||||||
Forfeited | 0.32 | (1,240,120 | ) | - | 1.25 | (1,712,275 | ) | - | ||||||||||||||||
Granted | 0.16 | 11,398,400 | 7.8 | 0.62 | 17,784,640 | 9.79 | ||||||||||||||||||
| ||||||||||||||||||||||||
Outstanding at December 31 | 0.33 | 35,191,540 | 7.42 | 0.38 | 27,003,260 | 8.12 |
(4)Fair value measurement:
The fair value of the options is measured at the grant date using the Black-Scholes Option pricing model and the assumptions used to calculate the fair value of the options are as follows:
| |||||
|
| ||||
|
| ||||
|
| ||||
|
| ||||
|
| ||||
|
|
F - 20
|
|
Note 8 - Share Capital (cont’d)
C.Share-based compensation (cont’d)
4. (cont'd)
(a)The weighted average share price is based on the Company’s Ordinary Share valuation as at the grant date.
(b)Expected life for the periods presented was determined according to the simplified method since, at the date of grant, the Company did not have enough history to make an estimate. This method effectively assumes that exercise occurs over the period from vesting until expiration, and therefore the expected term is the midpoint between the service period and the contractual term of the award. The simplified method is applicable to service conditions and for performance conditions that are probable of achievement. If meeting the performance condition is not probable, the Company will use the awards’ contractual term if the service period is implied, or the simplified method, if the service period is explicitly stated.
(c)Expected volatility is based on historical volatility over the most recent period commensurate with the expected term of the option. As the Company has a short trading history for its ordinary shares, when the Company's trading period is shorter than the expected term, the expected volatility is derived from the average historical share volatilities of several unrelated public companies within the Company’s industry that the Company considers to be comparable to its own business over a period equivalent to the option’s expected term.
(d)The risk-free rate for the expected term of the options is based on the Black-Scholes option-pricing model on the yields of U.S. Treasury securities with maturities appropriate for the expected term of employee share option awards.
Note 9 - Research and Development
Year ended | Year ended | |||||||
December 31, | December 31, | |||||||
2022 | 2021 | |||||||
USD thousands | USD thousands | |||||||
Consultants and subcontractors | 13,052 | 3,894 | ||||||
Salaries and related expenses | 2,867 | 1,789 | ||||||
Rent and maintenance | 245 | 114 | ||||||
Share-based compensation | 448 | 137 | ||||||
Other expenses | 365 | 400 | ||||||
16,977 | 6,334 |
F - 21
|
|
Note 10 - General and Administrative
Year ended | Year ended | |||||||
December 31, | December 31, | |||||||
2022 | 2021 | |||||||
USD thousands | USD thousands | |||||||
Salaries and related expenses | 3,435 | 943 | ||||||
Professional services | 2,596 | 1,695 | ||||||
Share-based compensation | 2,763 | 1,882 | ||||||
Fees to Directors | 231 | 244 | ||||||
Insurance | 1,084 | 1,024 | ||||||
Rent and maintenance | 24 | 29 | ||||||
Other expenses | 1,423 | 216 | ||||||
11,556 | 6,033 |
Note 11 - Income Taxes
A.Tax rates
Ordinary taxable income in Israel is subject to a corporate tax rate of 23%.
The Company’s US subsidiary, Chemomab Therapeutics Inc. ("Chemomab Inc.) is taxed separately under the U.S. tax laws.
Chemomab Inc. is subject to a federal flat tax rate of 21% and state tax as applicable.
Capital gain is subject to capital gain tax according to the corporate tax rate in the year the assets are sold.
B.Tax assessments
As of December 31, 2022, the Company’s tax reports through December 31, 2017 are considered closed to audit inspections by the Israeli Tax Authority (“ITA”) due to statute of limitation rules effective in Israel.
The Company has not yet been assessed by the ITA since inception.
C.Losses for tax purposes carried forward to future years
As of December 31, 2022, the Company and its subsidiaries had approximately $159 million (approximately $143 million as of December 31, 2021) of net operating loss carryforwards which are available to reduce future taxable income with no limitation on the period of use.
On March 27, 2020 and December 27, 2020, the President of the United States signed and enacted into law the Coronavirus Aid, Relief, and Economic Security Act (CARES Act) and the Consolidated Appropriations Act, 2021 (CAA). Among other provisions, the CARES Act and the CAA provide relief to U.S. federal corporate taxpayers through temporary adjustments to net operating loss rules, changes to limitations on interest expense deductibility, and the acceleration of available refunds for minimum tax credit carryforwards. The CARES Act also includes provisions for a carryback of any net operating loss (NOL) arising in a taxable year beginning after December 31, 2017, and before January 1, 2021, to each of the five taxable years preceding the taxable year in which the loss arises (carryback period).
F - 22
|
|
Note 11 - Income Taxes (cont’d)
C.Losses for tax purposes carried forward to future years (cont'd)
Chemomab Therapeutics Inc., a wholly owned subsidiary of the Company, filed an application with the US Internal Revenue Service to carryback net operating losses. Chemomab Therapeutics Inc received $351 thousand in December 2022 on account of 2016 and 2017 and expects to receive the remainder $183 thousand in 2023. Accordingly, a tax benefit in the total amount of $534 thousand was recorded in the Company’s statement of operations during 2022.
D.Deferred taxes
In respect of:
December 31, | December 31, | |||||||
2022 | 2021 | |||||||
USD thousands | USD thousands | |||||||
Net operating loss carry-forwards | 36,550 | 33,396 | ||||||
Share-based compensation expense | 1,774 | 1,147 | ||||||
Research and development costs | 2,858 | 1,449 | ||||||
Other | 13 | 38 | ||||||
Gross deferred tax assets | 41,195 | 36,030 | ||||||
Less - Valuation allowance | (41,195 | ) | (36,030) | |||||
| ||||||||
Net deferred tax assets | - | - |
In assessing the realizability of deferred tax assets, management considers whether it is more likely than not that some portion or all of the deferred tax assets will not be realized. The ultimate realization of deferred tax assets is dependent upon the generation of future taxable income during the periods in which those temporary differences become deductible. A valuation allowance is provided when it is more likely than not that the deferred tax assets will not be realized.
The Company has established a valuation allowance to offset deferred tax assets on December 31, 2022 and 2021 due to the uncertainty of realizing future tax benefits from its net operating loss carryforwards and other deferred tax assets. The net change in the total valuation allowance for the year ended at December 31, 2022 was an increase of approximately $5.2 million.
E.Roll forward of valuation allowance
Balance at January 1, 2021 | $ | 6,200 | ||
Currency transaction loss | 2,425 | |||
Tax assets acquired through merger | 24,535 | |||
Income tax expense | 2,870 | |||
Balance at December 31, 2021 | $ | 36,030 | ||
Currency transaction Income | (1,316 | ) | ||
Income tax expense | 6,481 | |||
Balance at December 31, 2022 | $ | 41,195 |
F - 23
|
|
Note 11 - Income Taxes (cont’d)
F.Reconciliation of theoretical income tax expense to actual income tax expense
A reconciliation of the Company’s theoretical income tax expense to actual income tax expense is as follows:
December 31, | December 31, | |||||||
2022 | 2021 | |||||||
USD thousands | USD thousands | |||||||
Loss before income taxes | (28,180 | ) | (12,478 | ) | ||||
Statutory tax rate | 23 | % | 23 | % | ||||
Theoretical tax benefit | (6,481 | ) | (2,870 | ) | ||||
| ||||||||
Change in temporary differences for which deferred taxes were not recognized | (1,696 | ) | (1,332 | ) | ||||
Tax rate differential | 20 | (101 | ) | |||||
Non-deductible expenses | 744 | 239 | ||||||
Losses and other items for which a valuation allowance was provided or benefit from loss carryforwards | 6,879 | 4,064 | ||||||
Actual income tax expense (Benefit) | (534 | ) | - |
G.Accounting for uncertainty in income taxes
For the year ended December 31, 2022, the Company did not have any unrecognized tax benefits and does not expect that the amount of unrecognized tax benefits will change significantly within the next 12 months. The Company’s accounting policy is to accrue interest and penalties related to unrecognized tax benefits as a component of income tax expense.
Note 12 - Related Parties Balances and Transactions
A.Balances with Related Parties:
The following Related Party payables are included in the consolidated Balance Sheets:
December 31, | December 31, | |||||||
2022 | 2021 | |||||||
USD thousands | USD thousands | |||||||
Employee and related expenses | 891 | 278 | ||||||
Accrued expenses | 58 | 72 | ||||||
| ||||||||
949 | 350 |
|
On September 19, 2022, the Company entered into a share purchase agreement with the Company's Co- Founders, see Note 8B(4).
F - 24
|
|
Note 12 - Related Parties Balances and Transactions (cont'd)
B.Transactions with Related Parties:
The following transactions with related parties are included in the consolidated Statements of Operations:
Year ended | Year ended | |||||||
December 31, | December 31, | |||||||
2022 | 2021 | |||||||
USD thousands | USD thousands | |||||||
Salaries and related expenses | 2,409 | 1,255 | ||||||
Share-based payments | 2,466 | 1,775 | ||||||
Professional Services | 231 | 244 | ||||||
Research and development | 36 | 36 | ||||||
| ||||||||
5,142 | 3,310 |
Note 13 - Net Loss Per Share Attributable to Ordinary Shareholders
Basic net loss per share is computed by dividing the net loss available to common stockholders by the weighted-average number of ordinary shares outstanding. Diluted net loss per share is computed similarly to basic net loss per share except that the denominator is increased to include the number of additional ordinary shares that would have been outstanding if the potential ordinary shares had been issued and if the additional ordinary shares of were dilutive. Diluted net loss per share is the same as basic net loss per share of ordinary share, as the effect of potentially dilutive securities is antidilutive.
The following table sets forth the computation of basic and diluted net loss per share attributable to ordinary shareholders for the periods presented:
Year ended | Year ended | |||||||
December 31 | December 31 | |||||||
2022 | 2021 | |||||||
In USD thousands, except share and per share data | ||||||||
Numerator: | ||||||||
Net loss | 27,646 | 12,478 | ||||||
| ||||||||
Denominator: | ||||||||
Weighted-average number of ordinary shares used in computing net loss per share attributable to ordinary shareholders, basic and diluted | 227,589,288 | 207,468,650 | ||||||
| ||||||||
Net loss per share attributable to ordinary shareholders, basic and diluted | 0.121 | 0.060 |
F - 25
|
|
Note 13 - Net Loss Per Share Attributable to Ordinary Shareholders (cont'd)
The potential number of ordinary shares that were excluded from the computation of diluted net loss per share attributable to ordinary shareholders for the periods presented since including them would have been anti-dilutive are as follows:
Year ended | Year ended | |||||||
December 31 | December 31 | |||||||
2022 | 2021 | |||||||
Number of shares | ||||||||
Outstanding options to purchase ordinary shares | 35,191,540 | 27,003,260 |
Note 14 - Subsequent Events
On January 13, 2023 the Company filed with the SEC a registration statement on form S-1 for the issuance and sale of up to $20,000,000 of its ADSs.
F - 26
Aegis Capital Corp. |
Amount Paid or to be Paid | Amount Paid or to be Paid | |||||||
SEC registration fee | $ | 3,306 | $ | 3,306 | ||||
FINRA filing fee | $ | 3,500 | $ | 1,050 | ||||
Legal fees and expenses (including underwriters' legal fees) | $ | 235,000 | $ | 300,000 | ||||
Accounting fees and expenses | $ | 45,710 | $ | 65,710 | ||||
Printing expenses | $ | 15,000 | $ | 15,000 | ||||
Depositary and transfer agent fees and expenses | $ | 152,280 | $ | 151,312 | ||||
Miscellaneous | $ | 10,000 | $ | 10,000 | ||||
Total | $ | 464,796 | $ | 546,378 |
a financial liability imposed on him or her in favor of another person pursuant to a judgment, including a settlement or arbitrator’s award approved by a court. However, if an undertaking to indemnify an office holder with respect to such liability is provided in advance, then such an undertaking must be limited to events which, in the opinion of the board of directors, can be foreseen based on the company’s activities when the undertaking to indemnify is given, and to an amount or according to criteria determined by the board of directors as reasonable under the circumstances, and such undertaking shall detail the abovementioned events and amount or criteria; and |
a breach of duty of care to the company or to a third party, including a breach arising out of the negligent conduct of an office holder; |
a breach of duty of loyalty, except to the extent that the office holder acted in good faith and had a reasonable basis to believe that the act would not prejudice the company; |
1. | To file, during any period in which offers or sales are being made, a post-effective amendment to this registration statement: |
a. | To include any prospectus required by Section 10(a)(3) of the Securities Act; |
b. | To reflect in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the registration statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the SEC pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than a 20% change in the maximum aggregate offering price set forth in the “Calculation of Registration Fee” table in the effective registration statement; and |
c. | To include any material information with respect to the plan of distribution not previously disclosed in the registration statement or any material change to such information in the registration statement. |
2. | That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof. |
3. | To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering. |
4. | That, for the purpose of determining liability under the Securities Act to any purchaser, each prospectus filed pursuant to Rule 424(b) as part of a registration statement relating to an offering, other than registration statements relying on Rule 430B or other than prospectuses filed in reliance on Rule 430A, shall be deemed to be part of and included in the registration statement as of the date it is first used after effectiveness. Provided, however, that no statement made in a registration statement or prospectus that is part of the registration statement or made in a document incorporated or deemed incorporated by reference into the registration statement or prospectus that is part of the registration statement will, as to a purchaser with a time of contract of sale prior to such first use, supersede or modify any statement that was made in the registration statement or prospectus that was part of the registration statement or made in any such document immediately prior to such date of first use. |
5. | That, for the purpose of determining liability of the registrant under the Securities Act to any purchaser in the initial distribution of the securities, the undersigned registrant undertakes that in a primary offering of securities of the undersigned registrant pursuant to this registration statement, regardless of the underwriting method used to sell the securities to the purchaser, if the securities are offered or sold to such purchaser by means of any of the following communications, the undersigned registrant will be a seller to the purchaser and will be considered to offer or sell such securities to such purchaser. |
a. | Any free writing prospectus relating to the offering prepared by or on behalf of the undersigned registrant or used or referred to by the undersigned registrant; |
b. | The portion of any other free writing prospectus relating to the offering containing material information about the undersigned registrant or its securities provided by or on behalf of the undersigned registrant; and |
c. | Any other communication that is an offer in the offering made by the undersigned registrant to the purchaser. |
CHEMOMAB THERAPEUTICS LTD. | ||
By: | /s/ Dale Pfost | |
Dale Pfost | ||
Chairman of the Board, Chief Executive Officer |
Signature | Title | Date | ||||
/s/ Dale Pfost | Chairman of the Board and Chief Executive Officer | March 21, 2023 | ||||
Dale Pfost | (Principal Executive Officer) | |||||
/s/ Donald Marvin | Chief Financial Officer, Executive Vice President and Chief Operating Officer | |||||
Donald Marvin | (Principal Financial and Accounting Officer) | |||||
* | March 21, 2023 | |||||
Adi Mor | ||||||
Director | March 21, 2023 | |||||
Nissim Darvish | ||||||
* | Director | March 21, 2023 | ||||
Alan Moses | ||||||
* | Director | March 21, 2023 | ||||
Claude Nicaise | ||||||
* | �� | Director | ||||
* | Director | |||||
/s/ | ||||||
Dale Pfost | ||||||
Attorney in Fact |
CHEMOMAB THERAPEUTICS, INC. | ||
By: | /s/ Dale Pfost | |
Dale Pfost | ||