| Cover | Mar. 21, 2022 |
| Cover [Abstract] | |
| Document Type | 8-K |
| Amendment Flag | false |
| Document Period End Date | Mar. 21, 2022 |
| Entity File Number | 001-36294 |
| Entity Registrant Name | uniQure N.V. |
| Entity Central Index Key | 0001590560 |
| Entity Tax Identification Number | 00-0000000 |
| Entity Incorporation, State or Country Code | P7 |
| Entity Address, Address Line One | Paasheuvelweg 25a |
| Entity Address, City or Town | Amsterdam |
| Entity Address, Country | NL |
| Entity Address, Postal Zip Code | 1105 BP |
| City Area Code | +31 |
| Local Phone Number | 20-566-7394 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Title of 12(b) Security | Ordinary Shares, par value €0.05 per share |
| Trading Symbol | QURE |
| Security Exchange Name | NASDAQ |
| Entity Emerging Growth Company | false |
