Mail Stop 6010 							June 22, 2006 Mr. Jeffrey F. O`Donnell Chief Executive Officer PhotoMedex, Inc. 147 Keystone Drive Montgomerysville, PA 18936 Re:	PhotoMedex, Inc. Form 10-K for the year ended December 31, 2005 Filed March 16, 2006 File No. 0-11635 Dear. Mr. O`Donnell: 	We have completed our review of your Form 10-K and related filings and do not, at this time, have any further comments. 						Sincerely, 						Martin F. James 						Senior Assistant Chief Accountant