April 14, 2005

Via U.S. Mail

Richard F.  Hamm, Jr.
Senior Vice President,
Corporate Affairs,
General  Counsel and Secretary
Dendreon Corporation
3005 First Avenue
Seattle, WA 98121

RE:		Dendreon Corporation
      Form 10-K for the fiscal year ended December 31, 2003
      Form 10-K for the fiscal year ended December 31, 2004
      Response letter dated March 17, 2005
		File No. 0-30681


Dear Mr. Hamm:

      We have reviewed the above filings and response letter and
have
the following comment.  We have limited our review of your Forms
10-K
to disclosures relating to your contacts with countries that have
been identified as state sponsors of terrorism, and will make no
further review of the Forms 10-K.  Our review with respect to this
issue does not preclude further review by the Assistant Director
group with respect to other issues.  At this juncture, we are
asking
you to provide us with supplemental information, so that we may
better understand your disclosure.  Please be as detailed as
necessary in your response. After reviewing this information, we
may
or may not raise additional comments.

      Please understand that the purpose of our review process is
to
assist you in your compliance with the applicable disclosure
requirements and to enhance the overall disclosure in your
filings.
We look forward to working with you in these respects.  We welcome
any questions you may have about our comment or on any other
aspect
of our review.  Feel free to call us at the telephone number
listed
at the end of this letter.



General -
We note your March 17, 2005 response to our letter dated December
28,
2004.  While your letter makes clear that you considered
qualitative
factors in evaluating the materiality to your business and your
security holders of the fact that, under the Agreement, your
territory includes North Korea, it does not identify the
qualitative
factors you considered.  Please advise us of the consideration you
gave to factors such as risk to the Company`s reputation, and risk
of
possible corresponding negative impact on your share value, by
virtue
of the fact that the Agreement specifically contemplates that you
will have contacts with a country identified as a state sponsor of
terrorism and subject to U.S. economic sanctions.

In this regard, please note that future evaluations of the
materiality of the Agreement, and of any contacts you may have
with
North Korea pursuant to the Agreement, also should include careful
consideration of these specific types of qualitative factors.

Closing

      Please understand that we may have additional comments after
we
review your response to our comment.  Please contact me at (202)
942-
7817 if you have any questions about the comment or our review.


								Sincerely,




								Cecilia D. Blye, Chief
								Office of Global Security
Risk


cc: 	Jeffrey Riedler
		Assistant Director
		Division of Corporation Finance
Dendreon Corporation
April 14, 2005
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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549-0507

         DIVISION OF
CORPORATION FINANCE