September 14, 2018 Jiangping (Gary) Xiao Chief Financial Officer Professional Diversity Network, Inc. 801 W. Adams Street, Sixth Floor Chicago, Illinois 60607 Re: Professional Diversity Network, Inc. Registration Statement on Form S-3 Filed September 10, 2018 File No. 333-227249 Dear Mr. Xiao: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Bernard Nolan, Attorney-Advisor, at (202) 551-6515 or Jan Woo, Legal Branch Chief, at (202) 551-3453 with any questions. Sincerely, Division of Corporation Finance Office of Information Technologies and Services cc: Benjamin Tan