September 26, 2018 Ilan Danieli Chief Executive Officer Precipio, Inc. 4 Science Park New Haven, Connecticut 06511 Re: Precipio, Inc. Registration Statement on Form S-1 Filed September 14, 2018 File No. 333-227364 Dear Mr. Danieli: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Thomas Jones at 202-551-3602 with any questions. Sincerely, Division of Corporation Finance Office of Electronics and Machinery cc: Stephen M. Davis, Esq.