June 10, 2019 Joseph Moscato President and Chief Executive Officer Generex Biotechnology Corp 10102 USA Today Way Miramar, FL 33025 Re: Generex Biotechnology Corp Form 10-K for the Fiscal Year Ended July 31, 2018 Filed October 26, 2018 File No. 000-25169 Dear Mr. Moscato: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Healthcare & Insurance