July 8, 2019 Patrick J. Mahaffy President and Chief Executive Officer Clovis Oncology, Inc. 5500 Flatiron Parkway, Suite 100 Boulder, CO 80301 Re: Clovis Oncology, Inc. Registration Statement on Form S-3 Filed July 2, 2019 File No. 333-232503 Dear Mr. Mahaffy: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Jeffrey Gabor at 202-551-2544 with any questions. Sincerely, Division of Corporation Finance Office of Healthcare & Insurance cc: Thomas Mark, Esq.