United States securities and exchange commission logo June 29, 2020 Adam Berk Chief Executive Officer Stem Holdings, Inc. 2201 NW Corporate Blvd., Suite 205 Boca Raton, FL 33431 Re: Stem Holdings, Inc. Registration Statement on Form S-1 Filed June 17, 2020 File No. 333-239226 Dear Mr. Berk: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Ronald (Ron) Alper at 202-551-3329 with any questions. Sincerely, Division of Corporation Finance Office of Real Estate & Construction cc: Robert L. B. Diener