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                              September 3, 2020

       Alex Dunn
       Chief Executive Officer
       Executive Network Partnering Corporation
       137 Newbury Street
       7th Floor
       Boston, MA 02116

                                                        Re: Executive Network
Partnering Corporation
                                                            Registration
Statement on Form S-1
                                                            Filed August 24,
2020
                                                            File No. 333-248267

       Dear Mr. Dunn:

              We have reviewed your registration statement and have the
following comments. In
       some of our comments, we may ask you to provide us with information so
we may better
       understand your disclosure.

              Please respond to this letter by amending your registration
statement and providing the
       requested information. If you do not believe our comments apply to your
facts and
       circumstances or do not believe an amendment is appropriate, please tell
us why in your
       response.

              After reviewing any amendment to your registration statement and
the information you
       provide in response to these comments, we may have additional comments.

       S-1 filed 8/24/2020

       Risk Factors, page 23

   1.                                                   We note the exclusive
federal forum provision for Securities Act actions set forth in
                                                        Section 12.1(b) of your
amended and restated certificate of incorporation. However, your
                                                        disclosure on pages 53
and 131 states that for any action arising under the Securities
                                                        Act, the Court of
Chancery and the federal district court for the District of Delaware shall
                                                        have concurrent
jurisdiction. Please reconcile.
       Principal Stockholders, page 109

   2.                                                   Please disclose in
footnote (4) to the table the names of the natural persons with voting or
                                                        dispositive power over
the shares.
 Alex Dunn
Executive Network Partnering Corporation
September 3, 2020
Page 2
Performance Shares, page 119

3.    We note your response to prior comment 3. As previously requested please
also clarify, if
      true, that the actions set forth in the penultimate paragraph of this
section would only
      apply after your partnering transaction (but not in connection with your
partnering
      transaction).
        We remind you that the company and its management are responsible for
the accuracy
and adequacy of their disclosures, notwithstanding any review, comments, action
or absence of
action by the staff.

       Refer to Rules 460 and 461 regarding requests for acceleration. Please
allow adequate
time for us to review any amendment prior to the requested effective date of
the registration
statement.

        You may contact William Demarest at 202-551-3432 or Kristina Marrone at
202-551-
3429 if you have questions regarding comments on the financial statements and
related
matters. Please contact Stacie Gorman at 202-551-3585 or Brigitte Lippmann at
202-551-
3713 with any other questions.



                                                           Sincerely,
FirstName LastNameAlex Dunn
                                                     Division of Corporation
Finance
Comapany NameExecutive Network Partnering Corporation
                                                     Office of Real Estate &
Construction
September 3, 2020 Page 2
cc:       Christian Nagler, Esq.
FirstName LastName