United States securities and exchange commission logo November 17, 2020 Frank D. Heuszel Chief Executive Officer Document Security Systems, Inc. 200 Canal View Boulevard, Suite 104 Rochester, New York 14623 Re: Document Security Systems, Inc. Registration Statement on Form S-1 Filed November 4, 2020 File No. 333-249857 Dear Mr. Heuszel: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Sherry Haywood, Staff Attorney at (202) 551-3345 with any questions. Sincerely, Division of Corporation Finance Office of Manufacturing