United States securities and exchange commission logo November 19, 2020 Daniel Vitt, Ph.D. President and Chief Executive Officer Immunic, Inc. 1200 Avenue of the Americas Suite 200 New York, NY 10036 Re: Immunic, Inc. Registration Statement on Form S-3 Filed November 13, 2020 File No. 333-250083 Dear Dr. Vitt: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Alan Campbell at 202-551-4224 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Ilan Katz, Esq.