United States securities and exchange commission logo April 13, 2021 J. Jacob Isaacs Chief Executive Officer Fourth Wave Energy, Inc. 75 E. Santa Clara St., 6th Floor San Jose, CA 95113 Re: Fourth Wave Energy, Inc. Registration Statement on Form S-1 Filed April 9, 2021 File No. 333-255168 Dear Mr. Isaacs: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact David Gessert at 202-551-2326 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences