United States securities and exchange commission logo May 5, 2021 David Stasse Executive Vice President and Chief Financial Officer Trinseo S.A. 1000 Chesterbrook Boulevard, Suite 300 Berwyn, PA 19312 Re: Trinseo S.A. Form 10-K for Fiscal Year Ended December 31, 2020 Filed February 22, 2021 File No. 001-36473 Dear Mr. Stasse: We have limited our review of your filing to the financial statements and related disclosures and have the following comment. In our comment, we may ask you to provide us with information so we may better understand your disclosure. Please respond to the comment within ten business days by providing the requested information or advise us as soon as possible when you will respond. If you do not believe our comment applies to your facts and circumstances, please tell us why in your response. After reviewing your response to the comment, we may have additional comments. Form 10-K for Fiscal Year Ended December 31, 2020 Notes to Consolidated Financial Statements Note 5 - Investments in Unconsolidated Affiliates, page F-19 1. Please provide us a reconciliation between your equity in earnings of unconsolidated affiliates, as reported in the consolidated statements of operations, and net income reported by Americas Styrenics on page F-61 for each period presented. David Stasse FirstName LastNameDavid Stasse Trinseo S.A. Comapany May 5, 2021NameTrinseo S.A. May 5, Page 2 2021 Page 2 FirstName LastName In closing, we remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. You may contact Frank Wyman at 202-551-3660 or Angela Connell at 202-551- 3426 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences