United States securities and exchange commission logo





                            May 12, 2021

       Umesh Patel
       Chief Executive Officer
       Fuse Group Holding Inc.
       805 W. Duarte Rd., Suite 102
       Arcadia, CA 91007

                                                        Re: Fuse Group Holding
Inc.
                                                            Form 10-K for the
Fiscal Year ended September 30, 2020
                                                            Filed December 16,
2020
                                                            Response Dated
March 19, 2021
                                                            File No. 333-202948

       Dear Mr. Patel:

              We have reviewed your March 19, 2021 response to our comment
letter and have the
       following comments. In some of our comments, we may ask you to provide
us with information
       so we may better understand your disclosure.

              Please respond to these comments within ten business days by
providing the requested
       information or advise us as soon as possible when you will respond. If
you do not believe our
       comments apply to your facts and circumstances, please tell us why in
your response.

             After reviewing your response to these comments, we may have
additional
       comments. Unless we note otherwise, our references to prior comments are
to comments in our
       March 10, 2021 letter.

       Form 10-K for the Fiscal Year ended September 30, 2020

       Notes to Consolidated Financial Statements
       Note 5 - Prepaid Expenses, page F-13

   1.                                                   We have read your
response to prior comment one, concerning your various disclosures
                                                        explaining that you
have entered into an agreement to acquire Portafolio en Investigacion
                                                        Ambiental S.A. de C.V.
(   Portafolio   ), including five mines in Mexico, in exchange for
                                                        14,285,715 shares of
your common stock. However, in your response you indicate that
                                                        Portafolio does not own
any mines but rather has only five concessions to explore for
                                                        minerals. You state
that the areas    have not been explored and have no actual operations
                                                        and that    Portafolio
does not own any facilities and equipment....
 Umesh Patel
FirstName
Fuse GroupLastNameUmesh  Patel
            Holding Inc.
Comapany
May        NameFuse Group Holding Inc.
     12, 2021
May 12,
Page 2 2021 Page 2
FirstName LastName
         We believe that you should promptly expand upon your earlier
disclosures to clarify each
         of the points outlined above. You should also emphasize that you have
no basis to form
         an expectation of there being any concentration of specific minerals
on the properties, or
         of being able to obtain the surface rights and permits that would be
necessary to extract
         minerals from the areas covered by the concessions, if any are ever
found.
2.       We note your response to prior comment two, regarding the Form 8-K
that you filed on
         February 16, 2021, stating    We believe the current report and
exhibit are fully factual and
         reliable in connection with the terms of the transaction, including
the identities of the
         parties and the specific properties being acquired....

         However, certain representations and warranties indicate that a
business with mining
         operations had been established. For example, Section 2.1(a) states
that Portfolio    ...has
         the right to conduct its business as currently conducted,    and
explains that you were
         provided access to    contracts for the purchase of the Company   s
output,    while Section
         2.1(m) states that Portfolio    holds all permits, licenses and
authorizations necessary to the
         conduct of its business, including without limitation, its mining
operations.

         We understand from your response that there is no business, no mining
operations, no
         contracts for the sale of output, and no permits or licenses to
conduct mining operations
         other than the concessions to explore; please clarify these points in
your amendments.
3.       In your response to prior comment one, regarding the status of your
agreement to acquire
         Portfolio, you state    we have issued the shares but have not
delivered them to the selling
         shareholders    and you indicate that various steps are incomplete.
Please revise your
         disclosure to clarify the status, including a description of the
uncertainties pertaining to
         the timeframe for completion, your current expectation for the closing
date, and the
         reasons you would describe the shares as issued but not delivered.

         If you retain the shares and have not completed the transaction, it is
unclear what basis
         you would have in GAAP for recognizing the asset "prepayment for
acquisition of mining
         rights" in your March 31, 2021 interim report. Please identify the
specific authoritative
         accounting guidance that you have relied upon in preparing this
report.
4.       We have read your response to prior comment three, regarding your
agreement to acquire
         E-Mo Biotech Holding, Inc. (   E-Mo   ), and the Form 8-K that you
filed on March 17,
         2021, with the Share Exchange Agreement. You disclose that the
purchase price of $100
         million will be paid with shares of common stock, and indicate that a
change in control is
         expected to occur when the shares are issued in April 2021; although
you have not
         reported this event or indicated how you would be accounting for the
transaction.

         In the Form 8-K that you filed on February 11, 2021, you stated
E-Mo is involved in
         biology research and development including vaccines, immunological
treatment,
         diagnostic product development and similar treatments against the
Severe Acute
         Respiratory Syndrome Coronavirus 2 (   SARS-co-V2   ) and relevant
diseases.
 Umesh Patel
Fuse Group Holding Inc.
May 12, 2021
Page 3

         However, in Sections 4.14 and 5.8 of the Share Exchange Agreement,
there is only a
         general indication of assets, referencing    the Poliomyelitis Virus
Vaccine for Prevention
         of COVID-19 (   Vaccine   ) and related FDA application, test, trials,
data and permits,
         patents and patent applications for such Vaccine.    Provide us with a
summary of the
         business and activities conducted by E-Mo over the last three years,
including a list of all
         vaccines, treatments, and diagnostic products developed by E-Mo, and
details of the
         specific advances related to its COVID-19 vaccine, including the dates
of research and
         development and of any meaningful progress, to include testing,
clinical trials, permit and
         patent applications and grants, and correspondence with the FDA.

         Please amend your filings to clarify the extent to which E-Mo has
engaged and advanced
         in all of these areas, including the extent of revenues and earnings;
the products and
         services it provides and their relative significance; and with regard
to its efforts to create
         a COVID-19 vaccine, the stage of its research and development,
including the timeline
         and steps that would be required to assess viability, obtain
regulatory approvals, and
         market such a product; and explain how you view this prospect in light
of the competing
         vaccines that are already available and identify any material
uncertainties.
5.       Tell us how you determined that E-Mo would be properly valued at $100
million, describe
         the particular steps and timeline for completing this transaction, and
the date you will be
         filing the financial statements of this entity. Provide us with the
documentation underlying
         your valuation, including analyses and details of its financial
results, a listing of the
         specific assets and liabilities to be acquired, and a summary of any
material contracts.

         Indicate how you plan to account for the transaction and explain your
rationale, with
         reference to the specific authoritative guidance and any corresponding
facts.
      You may contact Joseph Klinko at (202) 551-3824 or Mark Wojciechowski at
(202) 551-
3759 with any questions..



FirstName LastNameUmesh Patel                                    Sincerely,
Comapany NameFuse Group Holding Inc.
                                                                 Division of
Corporation Finance
May 12, 2021 Page 3                                              Office of
Energy & Transportation
FirstName LastName