July 1, 2021

Via Email

David P. Glatz
Stradley Ronan Steven & Young, LLP
191 N. Wacker Dr.
Suite 1601
Chicago, IL 60606
dglatz@stradley.com

       Re:     Nuveen Variable Rate Preferred & Income Fund
               Registration Statement on Form N-2
               File Nos. 333-256744, 811-23704

Dear Mr. Glatz:

        On June 3, 2021, you filed a registration statement on Form N-2 on
behalf of Nuveen
Variable Rate Preferred & Income Fund (the    Fund   ). We have reviewed the
registration
statement and have provided our comments below. Where a comment is made in one
location, it
is applicable to all similar disclosure appearing elsewhere in the registration
statement. All
capitalized terms not otherwise defined herein have the meaning given to them
in the registration
statement.

1. Please tell us if you have presented any test the waters materials to
potential investors in
   connection with this offering. If so, please contact us to discuss how to
provide us with
   copies of such materials.

                                         PROSPECTUS

Outside Front Cover, Page ii

2. In the third line of the paragraph titled,    Investment Policies,
disclosure states,    The Fund
   will invest at least 50% of its Managed Assets in securities that, at the
time of investment, are
   rated investment grade (rated BBB/Baa or higher) or are unrated but judged
to be of
   comparable quality by the Fund   s sub-adviser.    Please add disclosure
that clarifies how
   much the Fund intends to invest in below-investment grade securities.

3. In the third line of the paragraph titled,    Investment Policies,
disclosure states,
      Additionally, the Fund will invest more than 25% of its Managed Assets in
the securities of
   companies principally engaged in financial services.    Disclosure here and
throughout the
   registration statement (e.g., page 50 regarding    Investment Policies,
page 82 regarding
      Concentration and Financial Services Sector Risk,    page 8 of the
Statement of Additional

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      Information regarding    Investment Restrictions   ) refers variously to
the Fund concentrating
     in    financial services    and that    financial services    is a sector
or an industry. It is therefore
     difficult to understand what the Fund   s policy is regarding
concentration in an industry.
     Please revise disclosure throughout the registration statement
accordingly.

4. In the twelfth line of the paragraph titled,    Leverage,    disclosure
states,    In addition, the
   Fund may use derivatives that have the economic effect of leverage.
Please tell us how the
   Fund calculates its derivative positions for purposes of meeting the Fund
s 80% test.

Page 3     Preferred Securities

5. In the third line of the fourth paragraph, disclosure states,    The retail
segment is typified by
   $25 par value exchange-traded securities and the institutional segment is
typified by $1,000
   par value OTC securities. Both $25 and $1,000 par value securities are often
callable at par
   value, typically at least five years after their original issuance date.
Please revise this
   disclosure using plain English.

Page 6     Other Equity Securities

6.    In the second line, disclosure states,    Additional types of equity
securities (other than
     preferred securities) in which the Fund may invest include convertible
securities (discussed
     below), real estate investment trusts (   REITs   ), warrants, rights,
depositary receipts (which
     reference ownership of underlying non-U.S. securities) and other types of
securities with
     equity characteristics.    Please specify the    other types of securities
with equity
     characteristics.

Page 10     Investment Policies

7. In the second line of the second paragraph, disclosure refers to    IMF.
Please define the
   term.

Page 19     Special Redemption Rights Risk

8. In the first line, disclosure states,    In certain circumstances, an issuer
of preferred securities
   may redeem the securities at par prior to their stated maturity date.
Please revise this
   sentence using plain English.

Page 21     Contingent Capital Securities or Contingent Convertible Securities

9. In the third line, disclosure states,    CoCos generally provide for
mandatory conversion into
   the common stock of the issuer or a write-down of the principal amount or
value of the
   CoCos upon the occurrence of certain    triggers.    These triggers are
generally linked to
   regulatory capital thresholds or regulatory actions calling into question
the issuing banking
   institution   s continued viability as a going-concern. Equity conversion or
principal write-
   down features are tailored to the issuer and its regulatory requirements
and, unlike traditional



                                                   2

     convertible securities, conversions are not voluntary.    Please revise
this disclosure using
    plain English.

Page 47     Summary of Fund Expenses

10. Earlier disclosure refers to the Fund   s use of various swaps as a
principal investment
    strategy. If the Fund will derive its returns principally from swaps,
please include a footnote
    to the fee table disclosing the cost of investing in swaps. The footnote
should explain that the
    embedded cost of the swaps, and the operating expenses of any reference
assets, are indirect
    expenses of the Fund that are not included in either the fee table or the
expense example.
    Please also provide an estimate of such costs, as a percentage of Fund
assets for the most
    recent fiscal year.

Page 79     Debt Securities Risk

11.     In the first line of the second paragraph, disclosure states,
Additionally, the Fund may be
exposed to certain debt securities risks through its sukuk investments.    This
is the first mention
of sukuk investments. Please add disclosure about sukuk investments to the
strategy section, and
ensure that there is enough detail for the reader to have a basis to understand
the disclosure here.

Page 91     Inverse Floating Rate Securities Risk

12.     In the first line of the first paragraph, disclosure states,    The
Fund may invest in inverse
floating rate securities issued by special purpose trusts that have recourse to
the Fund. In Nuveen
Fund Advisors    and Nuveen Asset Management   s discretion, the Fund may enter
into a separate
shortfall and forbearance agreement with the third party granting liquidity to
the floating rate
security holders of the special purpose trust.    Please revise this disclosure
using plain English.

Page 109     Redemption, Purchase and Sale of Preferred Shares

13.     If applicable, please discuss any limitations or restrictions on the
Fund if dividend
payments are past due. Please also disclose any restrictions on paying
dividends. See Item
10.1.b. of Form N-2.

                     STATEMENT OF ADDITIONAL INFORMATION

Page 8     Investment Restrictions

14.     Regarding the fourth investment restriction, the Fund   s concentration
policy appears to
reserve discretion as to when or whether the Fund would concentrate. It has
been the staff   s
longstanding position that a fund may not change its policies with respect to
concentration
without a shareholder vote, whether or not the fund previously disclosed that
it may do so, unless
the statement of investment policy clearly indicates when and under what
conditions any changes
between concentration and non-concentration would be made. Therefore, please
revise the
Fund   s policy to remove this discretion or to clearly indicate when and under
what conditions



                                                 3

 those changes would be made. See Statements of Investment Policies of Money
Market Funds
Relating to Industry Concentration, Investment Company Act Release No. 9011
(Oct. 30, 1975).


                                              PART C

Item 25: Financial Statements and Exhibits

15.     Please confirm that the Fund   s By-laws do not substantively differ
from the By-laws of
the existing Nuveen closed-end funds regarding mandatory arbitration, control
share
acquisitions, jury trial waiver, exclusive forum, and derivative actions.

                                     *   *     *        *     *   *

        We note that portions of the filing are incomplete. We may have
additional comments on
such portions when you complete them in a pre-effective amendment, on
disclosures made in
response to this letter, on information provided supplementally, or on exhibits
added in any pre-
effective amendment.

       A response to this letter should be in the form of a pre-effective
amendment filed
pursuant to Rule 472 under the Securities Act. The pre-effective amendment
filing should be
accompanied by a supplemental letter that includes your responses to each of
these comments.
Where no change will be made in the filing in response to a comment, please
indicate this fact in
your supplemental letter and briefly state the basis for your position.

        We remind you that the company and its management are responsible for
the accuracy
and adequacy of their disclosures, notwithstanding any review, comments,
action, or absence of
action by the staff.

       Should you have any questions regarding this letter, please contact me
at (202) 551-5166.

                                                            Sincerely,
                                                            /s/ Lisa N. Larkin
                                                            Senior Counsel

cc:    John Lee, Branch Chief
       Christian Sandoe, Assistant Director




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