United States securities and exchange commission logo November 17, 2021 David Renas Chief Financial Officer ObsEva SA Chemin des Aulx, 12 1228 Plan-les-Ouates Geneva, Switzerland Re: ObsEva SA Registration Statement on Form F-1 Filed November 10, 2021 File No. 333-260974 Dear Mr. Renas: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Joe McCann at (202) 551-6262 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Ryan Sansom, Esq.