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                   February 9, 2022

       Andrey Zarur
       President and Chief Executive Officer
       GreenLight Biosciences Holdings, PBC
       200 Boston Avenue
       Medford, Massachusetts 02155

                                                        Re: GreenLight
Biosciences Holdings, PBC
                                                            Registration
Statement on Form S-1
                                                            Filed February 7,
2022
                                                            File No. 333-262574

       Dear Dr. Zarur:

              This is to advise you that we have not reviewed and will not
review your registration
       statement.

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

              Please contact Michael Davis at 202-551-4385 or Celeste Murphy at
202-551-3257 with
       any questions.




                   Sincerely,


                   Division of Corporation Finance

                   Office of Life Sciences
       cc:                                              John D. Hancock