United States securities and exchange commission logo April 28, 2022 Gabrielle Heaton Director of Finance and Administration Kazia Therapeutics Ltd Three International Towers Level 24 300 Barangaroo Avenue Sydney, New South Wales 2000 Australia Re: Kazia Therapeutics Ltd Form 20-F for the fiscal year ended June 30, 2021 Filed October 7, 2021 File No. 000-29962 Dear Ms. Heaton: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences