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                               May 27, 2022

       Tao Xu
       Chief Financial Officer
       KE Holdings Inc.
       Oriental Electronic Technology Building
       No. 2 Chuangye Road, Haidian District
       Beijing 1000086
       People's Republic of China

                                                        Re: KE Holdings Inc.
                                                            Form 20-F for the
Fiscal Year Ended December 31, 2021
                                                            Filed April 19,
2022
                                                            Form 20-F for the
Fiscal Year Ended December 31, 2020
                                                            Filed April 6, 2021
                                                            File No. 001-39436

       Dear Mr. Xu:

              We have reviewed your May 19, 2022 response to our comment letter
and the Form 20-F
       filed April 19, 2022 and have the following comments. In some of our
comments, we may ask
       you to provide us with information so we may better understand your
disclosure.

              Please respond to these comments within ten business days by
providing the requested
       information or advise us as soon as possible when you will respond. If
you do not believe our
       comments apply to your facts and circumstances, please tell us why in
your response.

                                                        After reviewing your
response to these comments, we may have additional comments.

       FORM 20-F FOR THE FISCAL YEAR ENDED DECEMBER 31, 2021

       Item 3. Key Information, page 4

   1.                                                   Please revise the first
paragraph of this section to disclose that this VIE structure involves
                                                        unique risks to
investors. Please also disclose that investors may never hold equity
                                                        interests in the
Chinese operating company.
   2.                                                   We note the disclosure
on page 4 regarding the percentage of cash, cash equivalents and
                                                        restricted cash, total
assets, and revenues relating to the business operations of the VIE.
                                                        Please provide balanced
disclosure to clarify the potential impact upon your overall
                                                        business, including the
availability of the technology you use in your operations.
 Tao Xu
FirstName  LastNameTao Xu
KE Holdings  Inc.
Comapany
May        NameKE Holdings Inc.
     27, 2022
May 27,
Page 2 2022 Page 2
FirstName LastName
3.       Please revise the last paragraph on page 6 to clearly disclose whether
these risks could
         result in a material change in your operations.
4.       We continue to note disclosures referencing control over the VIE such
as on page 4, we
            rely on contractual arrangements among our PRC subsidiaries, the
VIEs and their
         shareholders to control the business operations of the VIEs,    and
KE Holdings Inc.
         controls, and receives economic benefits from, the VIEs through the
VIE contractual
         arrangements.    However, neither the investors in the holding company
nor the holding
         company itself have an equity ownership in, direct foreign investment
in, or control of,
         through such ownership or investment, the VIE. Any references to
control or benefits that
         accrue to you because of the VIE should be limited to a clear
description of the conditions
         you have satisfied for consolidation of the VIE under U.S. GAAP.
Please revise.
Permissions Required from the PRC Authorities for our Operations, page 8

5.       We note the disclosure that you are not required to obtain permissions
or approvals from
         the CSRS, CAC or any other PRC governmental authorities in connection
with the
         issuance of securities to foreign investors. Please disclose how you
reached such a
         determination (e.g. internal legal analysis, opinion of external
counsel or other advisor,
         etc.) To the extent you are relying upon the opinion of counsel,
please name and file their
         consent.
The Holding Foreign Companies Accountable Act, page 8

6.       Please disclose whether your auditor is subject to the determinations
announced by the
         PCAOB on December 16, 2021 and whether and how the Holding Foreign
Companies
         Accountable Act and related regulations will affect your company.
Please also disclose
         whether as a result of the auditor not being able to be inspected by
the PCAOB, the
         company is expected to be, or is, a Commission Identified Issuer and
how that will affect
         your company. Similarly revise the risk factor on page 63.
Summary of Risk Factors, page 22

7.       In your summary of risk factors, describe the significant regulatory,
liquidity, and
         enforcement risks with cross-references to the more detailed
discussion of these risks in
         the annual report. For example, specifically discuss risks arising
from the legal system in
         China, including risks and uncertainties regarding the enforcement of
laws and that rules
         and regulations in China can change quickly with little advance
notice; and the risk that
         the Chinese government may intervene or influence your operations at
any time, or may
         exert more control over offerings conducted overseas and/or foreign
investment in China-
         based issuers, which could result in a material change in your
operations and/or the value
         of your securities. Acknowledge any risks that any actions by the
Chinese government to
         exert more oversight and control over offerings that are conducted
overseas and/or foreign
         investment in China-based issuers could significantly limit or
completely hinder your
         ability to offer or continue to offer securities to investors and
cause the value of such
 Tao Xu
KE Holdings Inc.
May 27, 2022
Page 3
         securities to significantly decline or be worthless.
Risk Factors, page 24

8.       We note the disclosure on page 55 regarding the opinion of your PRC
legal counsel that
         you do not need approval of CSRC under the M&A Rules. Please name
counsel and
         provide their consent.
9.       Given recent statements by the Chinese government indicating an intent
to exert more
         oversight and control over offerings that are conducted overseas
and/or foreign investment
         in China-based issuers, please revise the second risk factor on page
55 to acknowledge the
         risk that any such action could significantly limit or completely
hinder your ability to offer
         or continue to offer securities to investors and cause the value of
such securities to
         significantly decline or be worthless.
Enforceability of Civil Liabilities, page 149

10.      Please identify each officer and/or director located in China or Hong
Kong and disclose
         that it will be more difficult to enforce liabilities and enforce
judgments on those
         individuals. For example, revise to discuss more specifically the cost
and time
         constraints. Also, please similarly revise the risk factor on page 61.
        You may contact Babette Cooper, Staff Accountant at (202) 551 - 3396 or
Wilson Lee at
(202) 551 - 3468 if you have questions regarding comments on the financial
statements and
related matters.



FirstName LastNameTao Xu                                        Sincerely,
Comapany NameKE Holdings Inc.
                                                                Division of
Corporation Finance
May 27, 2022 Page 3                                             Office of Real
Estate & Construction
FirstName LastName