United States securities and exchange commission logo June 1, 2022 Chaya Hendrick Chief Executive Officer SmartMetric, Inc. 3960 Howard Hughes Parkway, Suite 500 Las Vegas, Nevada 89169 Re: SmartMetric, Inc. Registration Statement on Form S-1 Filed May 23, 2022 File No. 333-265152 Dear Ms. Hendrick: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Gregory Herbers at 202-551-8028 with any questions. Sincerely, Division of Corporation Finance Office of Manufacturing