United States securities and exchange commission logo June 10, 2022 Marvin Slosman President and Chief Executive Officer InspireMD, Inc. 4 Menorat Hamaor St. Tel Aviv, Israel 674483 Re: InspireMD, Inc. Registration Statement on Form S-3 Filed June 3, 2022 File No. 333-265409 Dear Mr. Slosman: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Michael Davis at 202-551-4385 or Christopher Edwards at 202-551- 6761 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Gary Emmanuel