United States securities and exchange commission logo July 28, 2022 Kyle Casey Chief Financial Officer Twinlab Consolidated Holdings, Inc. 4800 T-Rex Avenue, Suite 225 Boca Raton, FL 33431 Re: Twinlab Consolidated Holdings, Inc. Form 10-K for the Fiscal Year Ended December 31, 2021 Filed March 29, 2022 File No. 000-55181 Dear Mr. Casey: We have limited our review of your filing to the financial statements and related disclosures and have the following comments. In some of our comments, we may ask you to provide us with information so we may better understand your disclosure. Please respond to these comments within ten business days by providing the requested information or advise us as soon as possible when you will respond. If you do not believe our comments apply to your facts and circumstances, please tell us why in your response. After reviewing your response to these comments, we may have additional comments. Form 10-K for the Fiscal Year Ended December 31, 2021 Item 9A. Controls and Procedures. Management's Annual Report on Internal Control over Financial Reporting, page 31 1. We note that you performed an assessment of your internal control over financial reporting as of December 31, 2021 and that you have material weaknesses that existed as of December 31, 2021. However, you did not clearly disclose your management s conclusion on the effectiveness of your internal control over financial reporting as of December 31, 2021. Please confirm you will clearly state in future filings whether or not your internal controls were effective at the end of the period. Refer to the guidance in Item 308(a)(3) of Regulation S-K. Kyle Casey FirstName LastNameKyle CaseyInc. Twinlab Consolidated Holdings, Comapany July NameTwinlab Consolidated Holdings, Inc. 28, 2022 July 28, Page 2 2022 Page 2 FirstName LastName Note 2- Summary of Significant Accounting Policies, page 64 2. Please provide to us, and confirm you will disclose in future filings, the disclosures required by ASC 606 regarding your accounting policy for Revenue Recognition. In closing, we remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. You may contact Tara Harkins at (202) 551-3639 or Mary Mast, Senior Accountant, at (202) 551-3613 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences