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                     September 13, 2022

       Eliot Forster
       CEO
       F-star Therapeutics, Inc.
       Eddeva B920 Babraham Research Campus
       Cambridge, United Kingdom CB22 3AT

                                                        Re: F-star
Therapeutics, Inc.
                                                            Form 10-K for the
year ended December 31, 2021
                                                            File Number 1-37718

       Dear Mr. Forster:

              We have completed our review of your filing. We remind you that
the company and its
       management are responsible for the accuracy and adequacy of their
disclosures, notwithstanding
       any review, comments, action or absence of action by the staff.




                     Sincerely,


                     Division of Corporation Finance

                     Office of Life Sciences