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                              September 19, 2022

       Ari Bousbib
       Chairman, Chief Executive Officer and President
       IQVIA Holdings, Inc.
       4820 Emperor Blvd.
       Durham, NC 27703

                                                        Re: IQVIA Holdings,
Inc.
                                                            Definitive Proxy
Statement on Schedule 14A
                                                            Filed April 12,
2022
                                                            File No. 001-35907

       Dear Mr. Bousbib:

             We have limited our review of your most recent definitive proxy
statement to those issues
       we have addressed in our comments.

               Please respond to these comments by confirming that you will
enhance your future proxy
       disclosures in accordance with the topics discussed below as well as any
material developments
       to your risk oversight structure. For guidance, refer to Item 407(h) of
Regulation S-K.

       Definitive Proxy Statement on Schedule 14A filed April 12, 2022

       General

   1.                                                   Please expand your
discussion of the reasons you believe that your leadership structure is
                                                        appropriate, addressing
your specific characteristics or circumstances. In your discussion,
                                                        please also address how
the experience of your Lead Director is brought to bear in
                                                        connection with your
board   s role in risk oversight.
   2.                                                   Please expand upon the
role that your Lead Director plays in the leadership of the board.
                                                        For example, please
enhance your disclosure to address whether or not your Lead Director
                                                        may:

                                                              represent the
board in communications with shareholders and other stakeholders;
                                                              require board
consideration of, and/or override your CEO on, any risk matters; or
                                                              provide input on
design of the board itself.
 Ari Bousbib
FirstName LastNameAri
IQVIA Holdings, Inc. Bousbib
Comapany 19,
September NameIQVIA
              2022     Holdings, Inc.
September
Page 2    19, 2022 Page 2
FirstName LastName
3.       Please expand upon how your board administers its risk oversight
function. For example,
         please disclose:

                why your board elected to retain direct oversight
responsibility for specific risks, such
              as social and environmental matters, rather than assign oversight
to a board
              committee;
                the timeframe over which you evaluate risks (e.g., short-term,
intermediate-term, or
              long-term) and how you apply different oversight standards based
upon the
              immediacy of the risk assessed;
                whether you consult with outside advisors and experts to
anticipate future threats and
              trends, and how often you re-assess your risk environment;
                how the board interacts with management to address existing
risks and identify
              significant emerging risks;
                whether you have a Chief Compliance Officer and to whom this
position reports; and
                how your risk oversight process aligns with your disclosure
controls and procedures.

        We remind you that the company and its management are responsible for
the accuracy
and adequacy of their disclosures, notwithstanding any review, comments, action
or absence of
action by the staff.

      Please contact Christopher Dunham at (202) 551-3783 or Amanda Ravitz at
(202) 551-
3412 with any questions.



                                                                Sincerely,

                                                                Division of
Corporation Finance
                                                                Disclosure
Review Program