United States securities and exchange commission logo September 21, 2022 William McLain, Jr. Senior Vice President and Chief Financial Officer Eastman Chemical Company 200 South Wilcox Drive Kingsport, TN 37662 Re: Eastman Chemical Company Form 10-K for the Fiscal Year Ended December 31, 2021 Filed February 25, 2022 Form 10-Q for the Fiscal Quarter Ended June 30, 2022 Filed August 1, 2022 File No. 001-12626 Dear Mr. McLain: We have completed our review of your filings. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences