United States securities and exchange commission logo December 9, 2022 Will Brown Chief Financial Officer ObsEva SA Chemin des Aulx, 12 1228 Plan-les-Ouates Geneva, Switzerland Re: ObsEva SA Registration Statement on Form F-3 Filed December 9, 2022 File No. 333-268723 Dear Will Brown: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Tim Buchmiller at (202)551-3635 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Su Lian Lu, Esq.