United States securities and exchange commission logo January 18, 2023 David Tobias Chief Executive Officer Cannabis Sativa, Inc. 450 Hillside Dr. #A224 Mesquite, Nevada 89027 Re: Cannabis Sativa, Inc. Registration Statement on Form S-4 Filed January 10, 2023 File No. 333-269172 Dear David Tobias: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Scott Anderegg at 202-551-3342 with any questions. Sincerely, Division of Corporation Finance Office of Trade & Services