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                        March 21, 2023

       Maria Stahl
       Chief Legal Officer
       Fusion Pharmaceuticals Inc.
       270 Longwood Road South
       Hamilton, Ontario, Canada, L8P 0A6

                                                        Re: Fusion
Pharmaceuticals Inc.
                                                            Registration
Statement on Form S-3
                                                            Filed March 16,
2023
                                                            File No. 333-270604

       Dear Maria Stahl:

              This is to advise you that we have not reviewed and will not
review your registration
       statement.

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

                                                        Please contact Jimmy
McNamara at 202-551-7349 with any questions.




                        Sincerely,


                        Division of Corporation Finance

                        Office of Life Sciences
       cc:                                              Mitchell S. Bloom