United States securities and exchange commission logo August 14, 2023 Donghao Yang Chief Financial Officer Yatsen Holding Ltd Building No. 35, Art Port International Creation Center No. 2519 Xingang East Road, Haizhu District Guangzhou 510330 People s Republic of China Re: Yatsen Holding Ltd Form 20-F for the Fiscal Year Ended December 31, 2022 File No. 001-39703 Dear Donghao Yang: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Disclosure Review Program cc: Yuting Wu