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                          August 28, 2023

       Donna Lowery
       Executive Vice President & Chief Financial Officer
       The First Bancshares, Inc.
       6480 U.S. Highway 98 West,
       Hattiesburg, Mississippi 39402

                                                        Re: The First
Bancshares, Inc.
                                                            Registration
Statement on Form S-3
                                                            Filed August 22,
2023
                                                            File No. 333-274150

       Dear Donna Lowery:

              This is to advise you that we have not reviewed and will not
review your registration
       statement.

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

                                                        Please contact Aisha
Adegbuyi at 202-551-8754 with any questions.




                          Sincerely,


                          Division of Corporation Finance

                          Office of Finance
       cc:                                              David S. Park