United States securities and exchange commission logo October 13, 2023 James Cullem Chief Executive Officer Allarity Therapeutics, Inc. 24 School Street, 2nd Floor Boston, MA 02108 Re: Allarity Therapeutics, Inc. Registration Statement on Form S-3 Filed October 10, 2023 File No. 333-274923 Dear James Cullem: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Dillon Hagius at 202-551-7967 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Daniel B. Eng