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                          November 9, 2023

       William M. Greenman
       President and Chief Executive Officer
       Cerus Corporation
       1220 Concord Ave., Suite 600
       Concord, California 94520

                                                        Re: Cerus Corporation
                                                            Registration
Statement on Form S-3
                                                            Filed November 2,
2023
                                                            File No. 333-275284

       Dear William M. Greenman:

              This is to advise you that we have not reviewed and will not
review your registration
       statement.

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

                                                        Please contact Juan
Grana at 202-551-6034 with any questions.




                          Sincerely,


                          Division of Corporation Finance

                          Office of Industrial Applications and

                          Services
       cc:                                              Chrystal Menard, Esq.