United States securities and exchange commission logo December 26, 2023 Brian Mitts Chief Financial Officer NexPoint Real Estate Finance, Inc. 300 Crescent Court, Suite 700 Dallas, Texas 75201 Re: NexPoint Real Estate Finance, Inc. Registration Statement on Form S-3 Filed December 20, 2023 File No. 333-276177 Dear Brian Mitts: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Ronald (Ron) E. Alper at 202-551-3329 with any questions. Sincerely, Division of Corporation Finance Office of Real Estate & Construction cc: Charles T. Haag