Bio-Rad Laboratories, Inc. SUMMARY OF OPERATIONS (In thousands, except per share data) ________________________________________________________________________________________________________________________ Year Ended December 31, 2000 1999 1998 1997 1996 1995 Net sales (1) $725,884 $555,399 $447,863 $432,078 $423,262 $400,935 Cost of goods sold (2) 343,364 255,223 202,438 189,331 182,046 171,942 Gross profit 382,520 300,176 245,425 242,747 241,216 228,993 Selling, general and administrative expense (1) 247,613 200,367 172,899 169,956 159,989 154,589 Product research and development expense 68,140 51,210 41,381 46,138 39,580 34,714 Purchased in-process research and development expense - 15,500 - - - - Restructuring costs - - - - 2,700 1,500 Income from operations 66,767 33,099 31,145 26,653 38,947 38,190 Other income (expense): Interest expense (30,612) (12,741) (3,731) (1,216) (3,027) (4,465) Other, net 9,288 (3,942) 6,814 (2,709) 553 (183) Income before taxes, extraordinary charge and cumulative effect of change in accounting principle 45,443 16,416 34,228 22,728 36,473 33,542 Provision for income taxes 13,633 4,695 9,926 6,364 9,118 8,386 Income before extraordinary charge and cumulative effect of change in accounting principle 31,810 11,721 24,302 16,364 27,355 25,156 Extraordinary charge (3) - - - - (1,176) - Cumulative effect of change in accounting principle, net of taxes of $515 (4) (710) - - - - - Net income $ 31,100 $ 11,721 $ 24,302 $ 16,364 $ 26,179 $ 25,156 Basic earnings per share before extraordinary charge and cumulative effect of change in accounting principle (5) $2.61 $0.97 $1.98 $1.33 $2.23 $2.06 Extraordinary charge (3)(5) - - - - (0.10) - Cumulative effect of change in accounting principle (4) (0.06) - - - - - Basic earnings per share (5) $2.55 $0.97 $1.98 $1.33 $2.13 $2.06 Weighted average common shares (5) 12,211 12,110 12,264 12,260 12,273 12,206 Cash dividends paid per common share - - - - - - Total assets $646,278 $668,862 $367,299 $351,876 $284,925 $285,098 Long-term debt, net of current maturities $203,360 $239,211 $ 42,339 $ 38,952 $ 6,721 $20,922 _______________________________________________________________________________________________________________________ <FN> (1) Restated to give effect to current presentation of freight charged to customers as a component of sales in compliance with FASB EITF Issue 00-10, Accounting for Shipping and Handling Fees and Costs. (2) In 1996, cost of goods sold includes a charge of $2.1 million for a write-down of inventory associated with the restructuring costs. (3) Extraordinary charge for redemption of subordinated debt: 1996 - $1,176, net of tax effect of $817. (4) Cummulative effect on prior years (to 12/31/99) of accounting change per SEC Staff Accounting Bulletin 101, on Revenue Recognition. (5) Restated to give effect to a stock split in the form of a 50% stock dividend in 1996. 1 Bio-Rad Laboratories, Inc. Consolidated Balance Sheets (In thousands) ________________________________________________________________________________________ December 31, Assets 2000 1999 Current Assets: Cash and cash equivalents $ 13,954 $ 17,087 Accounts receivable, less allowance of $10,255 in 2000 and $9,582 in 1999 182,242 193,898 Inventories: Raw materials 32,993 32,398 Work in process 30,071 31,936 Finished goods 69,455 61,943 Total inventories 132,519 126,277 Deferred tax assets 20,770 20,584 Prepaid expenses and other current assets 20,183 20,871 Total current assets 369,668 378,717 Property, Plant and Equipment: Land and improvements 8,337 8,937 Buildings and leasehold improvements 66,039 73,230 Equipment 180,827 168,401 Total property, plant and equipment 255,203 250,568 Accumulated depreciation (136,171) (124,626) Net property, plant and equipment 119,032 125,942 Goodwill, net of accumulated amortization of $13,990 in 2000 and $5,881 in 1999 90,970 105,350 Other Assets 66,608 58,853 Total Assets $646,278 $668,862 ________________________________________________________________________________________ The accompanying notes are an integral part of these statements. 2 Bio-Rad Laboratories, Inc. Consolidated Balance Sheets (In thousands, except share data) __________________________________________________________________________________________ December 31, Liabilities and Stockholders' Equity 2000 1999 Current Liabilities: Accounts payable $ 62,965 $ 64,737 Accrued payroll and employee benefits 52,354 59,919 Notes payable 6,490 11,547 Current maturities of long-term debt 11,656 10,413 Sales, income and other taxes payable 8,413 14,086 Other current liabilities 47,430 41,819 Total current liabilities 189,308 202,521 Long-Term Debt, net of current maturities 203,360 239,211 Deferred Tax Liabilities 8,992 7,016 Total liabilities 401,660 448,748 Commitments and Contingent Liabilities - - Stockholders' Equity: Preferred stock, $1.00 par value, 2,300,000 shares authorized; none outstanding - - Class A common stock, $1.00 par value, 15,000,000 shares authorized; outstanding 2000 - 10,042,200; 1999 - 9,977,862 10,042 9,978 Class B common stock, $1.00 par value, 6,000,000 shares authorized; outstanding 2000 - 2,435,928; 1999 - 2,484,716 2,436 2,485 Additional paid-in capital 19,120 18,830 Class A treasury stock, 244,499 shares in 2000 and (5,415) (7,392) 335,450 shares in 1999 at cost Retained earnings 231,821 200,993 Accumulated other comprehensive income(loss): Currency translation and other (13,386) (4,780) Total stockholders' equity 244,618 220,114 Total Liabilities and Stockholders' Equity $646,278 $668,862 __________________________________________________________________________________________ The accompanying notes are an integral part of these statements. 3 Bio-Rad Laboratories, Inc. Consolidated Statements of Income (In thousands, except per share data) ______________________________________________________________________________________________________________________ Year Ended December 31, 2000 1999 1998 Net sales $725,884 $555,399 $447,863 Cost of goods sold 343,364 255,223 202,438 Gross profit 382,520 300,176 245,425 Selling, general and administrative expense 247,613 200,367 172,899 Product research and development expense 68,140 51,210 41,381 Purchased in-process research and development expense - 15,500 - Income from operations 66,767 33,099 31,145 Other income (expense): Interest expense (30,612) (12,741) (3,731) Investment income, net 895 873 8,790 Other, net 8,393 (4,815) (1,976) Income before taxes and cumulative effect of change in accounting principle 45,443 16,416 34,228 Provision for income taxes 13,633 4,695 9,926 Income before cumulative effect of change in accounting principle 31,810 11,721 24,302 Cumulative effect on prior years (to 12/31/99) of accounting change, net taxes of $515 (see Note 1) (710) - - Net income $ 31,100 $ 11,721 $ 24,302 Basic earnings per share: Income before cumulative effect of change in accounting principle $2.61 $0.97 $1.98 Cumulative effect on prior years (to 12/31/99) of accounting change (0.06) - - Net income $2.55 $0.97 $1.98 Weighted average common shares 12,211 12,110 12,264 Diluted earnings per share: Income before cumulative effect of change in accounting principle $2.59 $0.96 $1.97 Cumulative effect on prior years (to 12/31/99) of accounting change (0.06) - - Net income $2.53 $0.96 $1.97 Weighted average common shares 12,284 12,165 12,358 _______________________________________________________________________________________________________________________ The accompanying notes are an integral part of these statements. 4 Bio-Rad Laboratories, Inc. Consolidated Statements of Cash Flows (In thousands) ________________________________________________________________________________________________________ Year Ended December 31, 2000 1999 1998 Cash flows from operating activities: Cash received from customers $707,046 $527,132 $436,029 Cash paid to suppliers and employees (632,803) (453,266) (395,265) Interest paid (27,124) (9,307) (3,833) Income tax payments (12,294) (17,237) (9,370) Miscellaneous payments (10,578) (2,341) (226) Net cash provided by operating activities 24,247 44,981 27,335 Cash flows from investing activities: Capital expenditures, net (31,406) (27,275) (21,176) Payments for acquisitions - (202,828) - Proceeds from divestitures 34,118 - - Purchases of marketable securities and investments (326) (2,216) (19,086) Sales of marketable securities and investments 795 6,600 16,367 Foreign currency hedges, net 6,115 2,401 (1,360) Net cash provided by (used in) investing activities 9,296 (223,318) (25,255) Cash flows from financing activities: Net payments on notes payable (4,325) (13,493) (1,365) Long-term borrowings 438,487 353,108 133,710 Payments on long-term debt (473,278) (151,788) (130,666) Arrangement and other fees for long-term acquisition financing (4,500) (5,008) - Proceeds from issuance of common stock 305 343 103 Purchase of treasury stock (378) (2,233) (4,665) Reissuance of treasury stock 2,083 1,322 1,978 Net cash provided by (used in) financing activities (41,606) 182,251 (905) Effect of exchange rate changes on cash 4,930 3,092 (1,937) Net increase (decrease) in cash and cash equivalents (3,133) 7,006 (762) Cash and cash equivalents at beginning of year 17,087 10,081 10,843 Cash and cash equivalents at end of year $ 13,954 $ 17,087 $ 10,081 ________________________________________________________________________________________________________ The accompanying notes are an integral part of these statements. 5 Bio-Rad Laboratories, Inc. Consolidated Statements of Changes in Stockholders' Equity (In thousands) ______________________________________________________________________ Year Ended December 31, 2000 1999 1998 Common Stock, $1.00 par value: Balance at beginning of year $12,463 $ 12,427 $ 12,421 Issuance of common stock 15 36 6 Balance at end of year 12,478 12,463 12,427 Additional Paid-In Capital: Balance at beginning of year 18,830 18,523 18,426 Issuance of common stock 290 307 97 Balance at end of year 19,120 18,830 18,523 Treasury Stock: Balance at beginning of year (7,392) (7,047) (6,006) Purchase of treasury stock (378) (2,233) (4,665) Reissuance of treasury stock 2,355 1,888 3,624 Balance at end of year (5,415) (7,392) (7,047) Retained Earnings: Balance at beginning of year 200,993 189,838 167,182 Net income 31,100 11,721 24,302 Reissuance of treasury stock at less than cost (272) (566) (1,646) Balance at end of year 231,821 200,993 189,838 Accumulated Other Comprehensive Income (Loss): Balance at beginning of year (4,780) 593 4,654 Other comprehensive loss (8,606) (5,373) (4,061) Balance at end of year (13,386) (4,780) 593 ________ ________ ________ Total Stockholders' Equity $244,618 $220,114 $214,334 Comprehensive Income: Net income $ 31,100 $ 11,721 $ 24,302 Currency translation adjustments (8,804) (4,833) 1,241 Net unrealized holding gains 533 66 819 Reclassification adjustments for gains included in net income (335) (606) (6,121) Total Comprehensive Income $ 22,494 $ 6,348 $ 20,241 _________________________________________________________________________ The accompanying notes are an integral part of these statements. 6 Bio-Rad Laboratories, Inc. Notes to Consolidated Financial Statements (In thousands of dollars, except share and per share data) _________________________________________________________________ 1. Significant Accounting Policies Basis of Presentation The consolidated financial statements include the accounts of Bio-Rad Laboratories, Inc. and all subsidiaries ("Bio-Rad" or the "Company") after elimination of intercompany balances and transactions. The preparation of financial statements in conformity with generally accepted accounting principles requires management to make estimates and assumptions that affect the amounts reported in the financial statements and accompanying notes. Changes in such estimates may affect amounts reported in the future. Reclassifications Certain prior period amounts have been reclassified to conform with the current year presentation. Pursuant to Financial Accounting Standards Board Emerging Issues Task Force Issue No.00-10, "Accounting for Shipping and Handling Fees and Costs", the Company has also reclassified freight billed to customers from selling, general and administrative expenses to net sales. The amounts reclassified were $5,910 and $5,921 for 1999 and 1998, respectively. Related freight costs are included in selling, general and administrative expenses as the responsibility for negotiating sales terms rests with the sales organization and not manufacturing. Cash and Cash Equivalents Cash and cash equivalents consist of cash and highly liquid in- vestments with original maturities of three months or less which are readily convertible into cash. Cash equivalents are stated at cost, which approximates fair market value. Concentration of Credit Risk Financial instruments that potentially subject the Company to concentration of credit risk consist primarily of trade accounts receivable. The Company performs credit evaluation procedures and with the exception of certain developing countries, generally does not require collateral. As a result of increased risk in these countries, some Bio-Rad sales are subject to collateral letters of credit. Credit risk is limited due to the large number of customers and their dispersion across many geographic areas. However, a significant amount of trade receivables are with national healthcare systems in countries within the European Economic Community. The Company does not currently anticipate a credit risk associated with these receiv- ables. 7 Inventory Valuation Inventories are valued at the lower of average cost or market and include material, labor and overhead costs. Property, Plant and Equipment Property, plant and equipment are carried at historical cost. Depreciation is computed on a straight-line basis over the estimated useful lives of the assets ranging from two to thirty years. Leasehold improvements are amortized over the lives of the respective leases or the lives of the improvements, whichever is shorter. Included in property, plant and equipment is reagent rental equipment. The Company provides these instruments to its customers for use with the Company's reagents. Depreciation is taken over the useful life of the equipment, which does not exceed five years. Marketable Securities The Company's marketable securities, included in Other Assets, are classified as available-for-sale and are recorded at current market value. Unrealized holding gains and losses are included as a separate component of stockholders' equity. Realized gains and losses are included in investment income. For the purpose of determining realized gains and losses, the cost of securities sold is based upon specific identification. Goodwill Goodwill, representing the excess of the cost over the net tangible and identifiable intangible assets of acquired businesses, is stated at cost and is amortized on a straight-line basis over the estimated future periods to be benefited, typically ten to fifteen years. Goodwill, other intangibles and other long-lived assets are periodically reviewed for impairment whenever events or changes in circumstances indicate that the carrying amount of an asset may not be recoverable. Revenue Recognition and Warranty Bio-Rad recognizes revenues when persuasive evidence of an arrangement exists, delivery has occurred, the sales price is fixed or determinable and collectibility is probable. Generally, these criteria are met at the time product is shipped. Provision is made at the time the related revenue is recognized for estimated product returns and other offerings which may occur under programs the Company has with its customers. The Company warrants certain equipment against defects in design, materials and workmanship, generally for one year. Upon shipment of equipment sold which includes a warranty, the Company establishes, as part of cost of goods sold, a provision for the expected costs of such warranty. 8 Foreign Currency Translation Balance sheet accounts of international subsidiaries are translated at the current exchange rate as of the end of the accounting period. Income statement items are translated at average exchange rates. The resulting translation adjustment is recorded as a separate component of stockholders' equity. Forward Exchange Contracts The Company does not use derivative financial instruments for speculative or trading purposes. As part of distributing its products, the Company regularly enters into intercompany transactions. The Company enters into forward foreign exchange contracts to hedge against future movements in foreign exchange rates that affect foreign currency denominated intercompany receivables and payables. These contracts generally have maturity dates of 60 days or less, relate primarily to currencies of industrial countries and are marked to market at each balance sheet date. The resulting gains or losses are included in other income and expense and offset exchange losses or gains on the related receivables and payables. Unrealized gains and losses are not deferred. Exchange gains and losses on these contracts are net of premiums and discounts which result from interest rate differentials between the U.S. and the countries of the currencies being traded. The cash flows related to these contracts are classified as cash flows from investing activities in the Statement of Cash Flows. Stock Compensation Plans Stock-based compensation is recognized using the intrinsic value method. For disclosure purposes, pro forma net income and earnings per share are provided as if the fair value method had been applied. Earnings Per Share Basic earnings per share are calculated on the basis of the weighted average number of common shares outstanding for each period. Diluted earnings per share are calculated assuming the exercise of certain stock options. Treasury stock is not considered outstanding for purposes of calculating weighted average shares. Fair Value of Financial Instruments The estimated fair value of financial instruments has been determined using available market information or other appropriate valuation methodologies. Estimates are not necessarily indicative of the amounts that could be realized in a current market exchange as considerable judgement is required in interpreting market data used to develop estimates of fair value. The use of different market 9 assumptions or estimation techniques could have a material effect of the estimated fair value amounts. The estimated fair value of Bio-Rad's financial instruments were as follows: Year Ended December 31, 2000 1999 Carrying Fair Carrying Fair Amount Value Amount Value Other assets $ 66,608 $ 65,000 $ 58,853 $ 59,000 Long-term debt $ 203,360 $ 212,000 $ 239,211 $ 239,000 Other Assets include financial instruments (e.g., notes receivable) that have fair values based on discounted cash flows, market quotations, and other appropriate valuation techniques. Long-term debt has an estimated fair value based on quoted market prices for the same or similar issues. For certain of the Company's financial instruments, including cash and cash equivalents, accounts receivable, marketable securities, notes payable, accounts payable, and forward exchange contracts, the carrying amounts approximate fair value. Accounting Change During the fourth quarter of 2000, the Company modified its revenue recognition policies to comply with guidelines outlined by the SEC in Staff Accounting Bulletin 101. The effects of the change in revenue recognition policies, as of January 1, 2000, are reported as the cumulative effect of an accounting change in the fourth quarter of 2000. This change did not have a significant effect on previously reported quarterly or prior years' income. 2. Acquisitions and Dispositions In July 2000, Accent Semiconductor Technology, Inc. ("ASTI") acquired the assets and certain liabilities of the Company's semiconductor and optoelectronic metrology business. The proceeds of approximately $36,000 represent $27,000 in cash, an $8,000 note receivable due in five years and an 18% passive equity interest in ASTI. The Company used $17,000 of the cash proceeds to reduce borrowings on the term loan portion of the Senior Credit facility. The equity interest in ASTI will be held as a long-term investment on the cost method. In October 1999, the Company acquired Pasteur Sanofi Diagnostic S.A., a French corporation ("PSD"), from its shareholders, Sanofi-Synthelabo S.A. and Institut Pasteur. PSD was founded by the Institut Pasteur and operates in the HIV and infectious disease diagnostic product market. 10 The Company paid $202,828 for all of the capital stock of PSD (and certain ancillary assets and assumed liabilities related to PSD). The purchase of PSD was financed with the proceeds from a $200,000 Senior Credit Agreement and a $100,000 Senior Subordinated Credit Agreement (see Note 5). The acquisition was accounted for using the purchase method of accounting. The 1999 operating results of PSD have been included in the Consolidated Statement of Income from the date of acquisition. As a result of the acquisition, the Company recorded $88,630 of goodwill. Goodwill reflects the excess of the purchase price, purchase liabilities and liabilities assumed over the fair value of net identifiable assets and in-process research and development projects acquired. Acquired in-process research and development of $15,500 was charged to expense in the fourth quarter of 1999 in accordance with generally accepted accounting principles. Purchase liabilities recorded included approximately $14,000 for severance and other employee costs and $4,000 for the consolidation and closure of certain leased facilities. The closure of facilities identified by the Company were completed in fiscal 2000, with lease payments, net of sublease revenues, continuing until all contractual obligations are met. As of December 31, 2000, expenses charged against these reserves were approximately $12,400 for severance and other employee costs and $1,600 for facilities and asset related write-offs. As the Company's 1999 financial statements include only three months of operations of PSD, the following selected unaudited pro forma information is being provided to present a summary of the combined results of Bio-Rad and PSD as if the acquisition had occurred as of January 1, 1998, giving effect to purchase accounting adjustments and actual costs of financing. The pro forma data is for informational purposes only and may not necessarily reflect the results of operations of Bio-Rad had PSD operated as part of the Company for the years ended December 31, 1999 and 1998. Unaudited Pro Forma Year Ended December 31, 1999 1998 Sales $727,900 $675,700 Net income (loss) $ 6,300 $(5,000) Basic earnings (loss)per share $0.52 $(0.41) The pro forma amounts reflect the results of operations for Bio-Rad and PSD and the following purchase accounting adjustments for the periods presented: Amortization of intangible assets and goodwill was based on the purchase price allocation for the period presented. Amortization of debt financing fees and expenses over the relative term of the following debt: Senior Credit Agreement, Senior Subordinated Credit Facility and Senior Subordinated Notes. 11 The additional interest expense on debt incurred to finance the acquisition was offset by a reduction of historical interest resulting from the elimination of PSD's debt. The estimated income tax effect on the pro forma adjustments, including a limitation on the deductibility of goodwill amortization. The pro forma statements do not include the $15,500 write- off of in-process research and development. This charge is included in the Consolidated Statements of Operations of the Company for 1999. 3. Investment Income Investment income in 1998 included $8,620 of net realized gains from the sales of marketable securities. The majority of the Company's marketable securities portfolio was sold in 1999 in preparation for the purchase of PSD. 4. Investment in Affiliates In December 1997, Bio-Rad began investing in Instrumentation Laboratory, S.p.A. (IL), an Italian based clinical diagnostics company. At December 31, 2000, Bio-Rad held approximately 28% of the outstanding stock of IL. A privately held company based in Spain controls over 51% of the outstanding stock of IL. The investment in IL is reviewed as published financial statements are made available to the Company. The most recently published financial statements for IL are as of November 1999. Given the limited availability of financial information, that no organized market exists for the shares to be traded and that Bio-Rad does not have the ability to significantly influence the operating and financial policies of IL, the investment has been recorded at its cost of $18,809 and is included in Other Assets. 5. Notes Payable and Long-Term Debt Notes payable include local credit lines maintained by the Company's subsidiaries aggregating approximately $25,611, of which $19,121 was unused at December 31, 2000. At December 31, 1999 these lines aggregated approximately $32,742, of which $21,195 was unused. The weighted average interest rate on these lines was 7.29% and 5.76% at December 31, 2000 and 1999, respectively. The Company guarantees most of these credit lines. 12 The principal components of Long-Term Debt are as follows: Year Ended December 31, 2000 1999 Senior Subordinated Credit Agreement $ - $100,000 Senior Credit Agreement: Term loan 63,000 100,000 Revolving credit agreement 1,750 49,000 Senior Subordinated Notes 148,467 - Capitalized leases 1,799 624 215,016 249,624 Less current maturities 11,656 10,413 Long-Term Debt $203,360 $239,211 In September 1999, the Company entered into a $200,000 Senior Credit Agreement and a $100,000 Senior Subordinated Credit Agreement to finance the acquisition of PSD and certain related assets and to provide funds for working capital needs. The Senior Credit Agreement included a term loan and revolving facility, each in the amount of $100,000. The term loan has since been reduced through permanent repayments to $63,000. 1999 debt issue costs related to these financings were $8,600. The Company entered into a $100,000 Senior Subordinated Credit Agreement dated January 31, 2000. This agreement had a one-year term and provided for an automatic rollover for an additional term maturing in September 2005. The proceeds of this transaction were used to replace the Senior Subordinated Credit Agreement dated September 30, 1999. Fees paid in January 2000 to replace and initiate the Senior Subordinated Credit Agreements were $4,000. This loan was repaid in February 2000. The Company sold $150,000 aggregate principal amount of Senior Subordinated Notes due in 2007 under an indenture dated February 17, 2000. The notes were offered at 98.832% of par and pay a fixed rate of interest of 11.625% per year. The notes are redeemable at the Company's option prior to the due date under certain terms and conditions. The Company's obligations under the notes are not secured and rank junior to all the Company's existing and future senior debt. The proceeds from this transaction were used (1) to repay the $100,000 Senior Subordinated Credit Agreement dated January 31, 2000, (2) to permanently retire $20,000 of the $100,000 term loan, and (3) to repay a portion of the outstanding borrowings under the revolving facility. The term loan and revolving facility are secured by an interest in the Company's assets through September 2004. Interest on both loans is based upon either the Eurodollar, the Federal Funds effective or corporate based (prime) rate. The term loan interest rate was 8.14% at December 31, 2000. The interest rate on the revolving facility at December 31, 2000 was 9.50%. A commitment fee ranging from .25% to .50% annually is charged on the daily unused portion of the revolving credit agreement. 13 The Senior Credit Agreement (including amendments) and the Senior Subordinated Notes require the Company, among other things, to comply with certain financial ratios and covenants. The Company was in compliance with all financial ratios as of December 31, 2000. These agreements also contain certain other restrictions, including limitations on payments of cash dividends, sales of assets, incurrence of indebtedness, the creation of liens, making certain investments and engaging in sale/leaseback transactions. Maturities of long-term debt at December 31, 2000, are as follows: 2001 - $11,656; 2002 - $14,566; 2003 - $17,540; 2004 - $21,036; 2005 - $0; thereafter - $150,218. 6. Income Taxes The U.S. and international components of income before taxes are as follows: Year Ended December 31, 2000 1999 1998 U.S. $ 6,429 $ 15,176 $ 24,173 International 39,014 1,240 10,055 Income before taxes and cumulative effect of change in accounting principle $ 45,443 $ 16,416 $ 34,228 The provision for income taxes consists of: Year Ended December 31, 2000 1999 1998 Current: U.S. Federal $ (4,576) $ 4,583 $ 8,564 International 15,284 8,323 4,974 U.S. State 585 853 374 11,293 13,759 13,912 Deferred 2,340 (9,064) (3,986) Provision for income taxes $ 13,633 $ 4,695 $ 9,926 14 The Company's income tax provision differs from the amount computed by applying the U.S. federal statutory rate to income before taxes as follows: Year Ended December 31, 2000 1999 1998 U.S. statutory tax rate 35% 35% 35% State taxes, net of federal income tax benefit 2 2 (1) Foreign Sales Corporation tax benefit (3) (10) (5) Research and development tax credit (2) (1) (1) Difference between U.S. and foreign tax rates (net of foreign tax credits) (1) 12 - Loss carryforwards utilized 0 (5) (1) Amortization of goodwill 1 4 - Foreign losses not benefited 4 31 - Favorable resolution of U.S. income tax disputes (1) (40) - Foreign exchange gain/(loss) recognized (6) - - Other 1 1 2 Provision for income taxes 30% 29% 29% Deferred income taxes reflect the net tax effect of temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for income tax purposes. Significant components of deferred tax assets and liabilities are as follows: Year Ended December 31, 2000 1999 Deferred Tax Assets: Reserves for obsolete inventory, warranty and bad debts $ 11,845 $ 12,622 Eliminated intercompany profit 3,823 3,661 Tax benefit of foreign loss carryforwards 12,629 16,457 Other 9,493 11,975 37,790 44,715 Valuation allowance (17,020) (24,131) Deferred Tax Assets $ 20,770 $ 20,584 Deferred Tax Liabilities: Deferred gain on condemnation $ 3,444 $ 3,522 Depreciation 1,325 1,567 Development cost of Hercules facility 1,483 1,385 Other 2,740 542 Deferred Tax Liabilities $ 8,992 $ 7,016 15 The valuation allowance is needed to reduce the deferred tax assets to an amount that is more likely than not to be realized. The net change in the valuation allowance in 2000 was a decrease of $7,111, primarily resulting from a utilization of tax loss carryforwards. Carryforwards resulting from the acquisition of PSD, which were not valued at the acquisition date, adjusted the recorded goodwill by approximately $5,800. The net change in 1999 was an increase of $18,789 primarily resulting from an increase in tax loss carryforwards. At December 31, 2000, Bio-Rad's international subsidiaries had combined net operating loss carryforwards of $31,759. A portion of these loss carryforwards will expire in the following years: 2002 - $629; 2003 - $145; 2004 - $172; and 2005 - $1,582. The remainder of these loss carryforwards have no expiration date. The utilization of these carryforwards is limited to the separate taxable income of each individual subsidiary. Bio-Rad does not provide for taxes which would be payable if the cumulative undistributed earnings of its international subsidiaries, approximately $55,666 at December 31, 2000, were remitted to the U.S. parent company. Unless it becomes advantageous for tax or foreign exchange reasons to remit a subsidiary's earnings, such earnings are indefinitely reinvested in subsidiary operations. The withholding tax and U.S. federal income taxes on these earnings, if remitted, would in large part be offset by tax credits. 7. Stockholders' Equity Stock Classification The Company's outstanding stock consists of Class A Common Stock (Class A) and Class B Common Stock (Class B). Each share of Class A and Class B participates equally in the earnings of Bio-Rad, and is identical in most respects except that Class A has limited voting rights. Each share of Class A is entitled to one-tenth of a vote on most matters, and each share of Class B is entitled to one vote. Additionally, Class A stockholders are entitled to elect 25% of the Board of Directors and Class B stockholders are entitled to elect the balance of the directors. Cash dividends may be paid on Class A shares without paying a cash dividend on Class B shares but no cash dividend may be paid on Class B shares unless at least an equal cash dividend is paid on Class A shares. Class B shares are convertible at any time into Class A shares on a one-for-one basis at the option of the stockholder. Stock Option Plans Bio-Rad maintains incentive and non-qualified stock option plans for officers and certain other key employees. Under the Amended 1994 Stock Option Plan (the Plan), the Company may grant options to its employees for up to 1,175,000 shares of common stock provided that no option shall be granted after March 1, 2004. Under the plans, Class A and Class B options are granted at prices not less than fair market value on the date of grant, are exercisable on a cumulative basis at a 16 rate not greater than 25% per annum commencing one year after the date of grant. Under an amendment to the Plan effective September 19, 2000, options expire ten years after the grant date with the exception of options granted in 1999 which expire five years after the grant date. The Company has made no charge to income with respect to any stock options. At the time options are exercised, the par value of the shares is credited to common stock and the excess is credited to additional paid-in capital. The Company may receive income tax benefits from the exercise of non-qualified stock options and from certain dispositions of stock received by employees under qualified or incentive stock options. The fair value of each option granted since January 1, 1995, was estimated on the date of the grant using the Black-Scholes option-pricing model with the following assumptions for grants in 2000, 1999 and 1998, respectively: no dividend yield for all periods; weighted average expected lives of 4.1 years in 2000, 3.9 in 1999 and 3.8 years in 1998; expected volatility of 30%, 34% and 35%; and risk-free interest rates of 6.71%, 4.79% and 5.44% for 2000, 1999 and 1998, respectively. 17 Activity under the plans is summarized below (amounts reported in the Price columns represent the weighted average exercise price): Year Ended December 31, 2000 1999 1998 Shares Price Shares Price Shares Price Outstanding at beginning of year 645,115 $24.18 561,047 $23.73 517,018 $21.40 Granted 530,945 22.52 166,080 19.89 150,653 23.54 Exercised (65,250) 18.95 (60,914) 8.47 (89,625) 10.09 Forfeited (111,338) 24.61 (19,712) 25.10 (14,677) 25.07 Expired (38,583) 18.21 (1,386) 7.37 (2,322) 9.46 Outstanding at end of year 960,889 $23.80 645,115 $24.18 561,047 $23.73 Options exercisable at year-end 272,048 $26.92 280,825 $24.72 222,539 $19.86 Weighted average fair value of options granted during the year $6.91 $6.46 $7.62 The following summarizes information about stock options outstanding at December 31, 2000: Options Outstanding Options Exercisable Number Weighted Average Number Range of Outstanding Remaining Weighted Average Exercisable Weighted Average Exercise Prices at 12/31/00 Contractual Life Exercise Price at 12/31/00 Exercise Price $19.69 - $19.88 120,281 3.1 years $19.74 27,668 $19.73 $21.50 - $21.50 295,865 9.7 21.50 0 0 $21.86 - $23.88 280,566 8.4 23.43 43,173 22.99 $23.94 - $35.89 264,177 6.1 28.63 201,207 28.75 $19.69 - $35.89 960,889 7.5 23.80 272,048 26.92 18 Employee Stock Purchase Plan Under the Amended and Restated 1988 Employee Stock Purchase Plan (the Plan), the Company has authorized the sale of 745,000 shares of Class A to eligible employees. The purchase price of the shares under the Plan is the lesser of 85% of the fair market value on the first day of each calendar quarter, or 85% of the fair market value on the last day of each calendar quarter. Employees may designate up to 10% of their compensation for the purchase of stock. Under the Plan, the Company sold 57,101 shares for $1,136, 58,762 shares for $1,098 and 51,446 shares for $1,129 to employees in 2000, 1999 and 1998, respectively. At December 31, 2000, 48,263 shares remained authorized under the Plan. The fair value of the employees' purchase rights since 1995 was estimated using the Black-Scholes model with the following assumptions for 2000, 1999 and 1998, respectively: no dividend yield for all periods; an expected life of three months for all periods; expected volatility ranging from 28% to 43%, from 22% to 35% and from 28% to 38%; and risk-free interest rates ranging from 5.45% to 6.46%, from 4.28% to 4.88% and from 4.27% to 5.23%. The weighted average fair value of those purchase rights granted in 2000, 1999 and 1998 was $5.10, $4.74 and $5.55, respectively. Pro Forma Disclosures If compensation cost for the Company's stock-based compensation plans had been determined based upon the fair value at grant dates for awards under those plans, the Company's net income and earnings per share would have been reduced to the pro forma amounts indicated below: Year Ended December 31, 2000 1999 1998 Net income As reported $31,100 $11,721 $24,302 Pro forma $29,874 $10,469 $23,026 Diluted earnings per As reported $2.53 $0.96 $1.97 share Pro forma $2.45 $0.86 $1.86 Since employee stock options vest over several years, and additional grants are likely to be made in the future, the disclosures may not be representative of the effects on reported pro forma net income or earnings per share in future years. 19 8. Earnings Per Share Weighted average shares used for diluted earnings per share include the dilutive effect of outstanding stock options of 73,000, 55,000 and 94,000 shares, for the years ended December 31, 2000, 1999 and 1998, respectively. Options to purchase 201,000, 261,000 and 229,000 shares of common stock were outstanding during 2000, 1999 and 1998, respectively, but were excluded from the computation of diluted earnings per share because the exercise price of the options was greater than the average market price of the common shares. The options were still outstanding at the end of 2000. 9. Other Income and Expense Other, net includes the following income and (expense) components: Year Ended December 31, 2000 1999 1998 Amortization of goodwill $(8,109) $(3,813) $(2,068) Exchange gains (losses) (420) (886) 22 Other non-operating litigation costs, net (3,339) 73 117 Gain on sale of fixed assets 5,155 - - Gain on sale of semiconductor division 16,690 - - Miscellaneous other items (1,584) (189) (47) Other, net $ 8,393 $(4,815) $(1,976) Non-operating litigation costs represent fees incurred to litigate intellectual property issues. Management does not believe that the outcome of these actions would have a material adverse effect on the future results of operations or the financial position of the Company. The Company will continue to incur costs relating to these issues. Exchange gains (losses) include premiums and discounts on forward foreign exchange contracts. 20 10. Supplemental Cash Flow Information The reconciliation of net income to net cash provided by operating activities is as follows: Year Ended December 31, 2000 1999 1998 Net income $31,100 $11,721 $24,302 Adjustments to reconcile net income to net cash provided by operating activities: Depreciation 33,722 23,090 18,510 Amortization 9,587 4,405 2,465 Foreign currency hedge transactions, net (6,115) (2,401) 1,360 Gains on dispositions of marketable securities (479) (850) (8,620) Increase in accounts receivable, net (329) (16,082) (5,739) (Increase) decrease in inventories (18,915) 4,095 (166) Decrease in other current assets 914 5,609 4,629 Increase (decrease) in accounts payable and other current liabilities (586) 26,153 (4,808) Increase (decrease) in income taxes payable (4,599) 4,804 1,040 Increase (decrease) in deferred taxes 3,383 (16,946) (5,292) Gain on sale of semiconductor division and fixed assets (21,845) - - Other (1,591) 1,383 (346) Net cash provided by operating activities $24,247 $44,981 $27,335 11. Commitments and Contingent Liabilities Rents and Leases Net rental expense under operating leases was $12,953 in 2000, $13,607 in 1999 and $12,622 in 1998. Leases are principally for facilities and automobiles. Annual future minimum lease payments at December 31, 2000, under operating leases are as follows: 2001 - $13,373; 2002 - $9,012; 2003 - $6,601; 2004 - $4,605; 2005 - $3,992; subsequent to 2005 - $7,214. Deferred Profit Sharing Retirement Plan The Company has a profit sharing plan covering substantially all U.S. employees. Contributions are made at the discretion of the Board of Directors. Bio-Rad has no liability other than for the current year's contribution. Contributions charged to income were $4,815, $4,030 and $3,566 in 2000, 1999 and 1998, respectively. Foreign Exchange Contracts The Company enters into forward foreign exchange contracts as a hedge against foreign currency denominated intercompany receivables and payables. At December 31, 2000, the Company had contracts maturing in January 2001 to sell foreign currency with a market value of $46,700 and to purchase foreign currency with a market value of $11,827. At 21 December 31, 1999, the Company had contracts maturing in January 2000 to sell foreign currency with a market value of $64,390 and to purchase foreign currency with a market value of $6,339. Letters of Credit In the ordinary course of business, the Company is at times required to post letters of credit. These letters of credit are required by certain insurance companies to ensure payments of certain charges. The Company was contingently liable for approximately $763 of standby letters of credit with a bank as of December 31, 2000. 12. Legal Proceedings The Company is a party to various claims, legal actions and complaints arising in the ordinary course of business. In the opinion of management, the outcome of these claims, legal actions and complaints would not have a material adverse effect on the future results of operations or the financial position of the Company. 13. Segment Information Bio-Rad is a multinational manufacturer and worldwide distributor of life science research products, clinical diagnostics and analytical instruments. Bio-Rad has three reportable segments: Life Science, Clinical Diagnostics and Analytical Instruments. These reportable segments are strategic business lines that offer different products and services and require different marketing strategies. The Life Science segment develops, manufactures, sells and services liquid chromatography, electrophoresis, gene amplification and transformation, imaging and image analysis, and nucleic acid sample preparation products. These products are sold to university and medical school laboratories, pharmaceutical and biotechnology companies, and government and industrial research facilities. The Clinical Diagnostics segment develops, manufactures, sells and services automated test systems, informatics systems, test kits and specialized quality controls for the healthcare market. These products are sold to reference laboratories, hospital laboratories, state newborn screening facilities, physicians office laboratories, and insurance and forensic testing laboratories. The Analytical Instruments segment develops, manufactures, sells and services FT-IR spectroscopy systems, semiconductor test and manufacturing instruments, spectral reference publications and software. These products are sold to industrial companies, government institutions, academia and forensic analysis laboratories. The Company's semiconductor business was sold in 2000 (see Note 2). 22 The accounting policies of the segments are the same as those described in Significant Accounting Policies (see Note 1). Segment profit or loss used for corporate management purposes includes an allocation of corporate expense based upon sales and an allocation of interest expense based upon accounts receivable and inventories. Segments are expected to manage only assets completely under their control. Accordingly, segment assets include primarily accounts receivable, inventories and gross machinery and equipment. Information regarding industry segments at December 31, 2000, 1999 and 1998 and for the years then ended is as follows: Life Clinical Analytical Science Diagnostics Instruments Segment net sales 2000 $269,805 $409,004 $ 53,101 1999 238,007 251,842 67,974 1998 213,570 172,008 66,100 Allocated interest expense 2000 $ 9,322 $ 19,370 $ 1,909 1999 3,761 7,775 1,206 1998 1,501 1,464 571 Depreciation and 2000 $ 6,380 $ 25,655 $ 858 amortization 1999 8,003 15,466 1,335 1998 7,328 11,242 1,652 Segment profit (loss) 2000 $ 15,342 $ 25,337 $ (2,395) 1999 16,643 18,749 2,928 1998 12,649 20,228 (2,166) Segment assets 2000 $152,179 $308,437 $ 14,441 1999 131,689 320,419 35,387 1998 124,219 129,089 38,607 Capital expenditures 2000 $ 6,763 $ 27,508 $ 755 1999 10,673 13,388 1,378 1998 6,487 15,213 1,912 Inter-segment sales are primarily from Life Science to Clinical Diagnostics and are priced to give Life Science a market representative gross margin. This represents the difference between total segment net sales and consolidated net sales. The difference between total segment allocated interest expense, depreciation and amortization, and capital expenditures and the corresponding consolidated amounts is attributable to the Company's corporate headquarters. 23 The following reconciles total segment profit to consolidated income before taxes and cumulative effect of change in accounting principle: Year Ended December 31, 2000 1999 1998 Total segment profit $38,284 $38,320 $30,711 Gross profit on inter-segment sales (1,755) (1,204) (1,925) Net corporate operating, interest and other income and expense not allocated to segments (8,671) (6,073) (3,348) Gain on sale of Semiconductor Division 16,690 - - Purchased in-process research and development - (15,500) - Investment income, net 895 873 8,790 Consolidated income before taxes and cumulative effect of change in accounting principle $45,443 $16,416 $34,228 The following reconciles total segment assets to consolidated total assets: December 31, 2000 1999 1998 Total segment assets $475,057 $487,495 $291,915 Cash and other current assets 54,907 58,542 36,968 Net property, plant and equipment excluding segment specific gross machinery and equipment (41,264) (41,378) (11,364) Other long-term assets 157,578 164,203 49,780 Total assets $646,278 $668,862 $367,299 The following presents sales to external customers by geographic area based primarily on the location of the use of the product or service: Year Ended December 31, 2000 1999 1998 Europe $275,062 $188,969 $141,004 Pacific Rim 128,311 110,729 88,917 United States 274,541 231,705 201,230 Other (primarily Canada and Latin America) 47,970 23,996 16,712 Total net sales $725,884 $555,399 $447,863 24 The following presents long-lived assets by geographic area based upon the location of the asset: Year Ended December 31, 2000 1999 1998 Europe $ 26,663 $ 34,129 $ 7,860 Pacific Rim 6,550 6,954 4,933 United States 239,817 247,293 118,628 Other (primarily Canada and Latin America) 3,580 1,769 489 Total long-lived assets $276,610 $290,145 $131,910 14. Quarterly Financial Data - (unaudited) Summarized quarterly financial data for 2000 and 1999 are as follows: First Second Third Fourth Quarter Quarter Quarter Quarter 2000 Net sales $185,463 $186,826 $175,761 $177,834 Gross profit 98,743 99,633 91,671 92,473 Net income 2,955 5,074 13,919 9,152 Basic earnings per share $0.24 $0.42 $1.14 $0.75 Diluted earnings per share $0.24 $0.41 $1.14 $0.74 1999 Net sales $127,378 $117,284 $115,066 $195,671 Gross profit 71,822 66,731 63,167 98,456 Net income (loss) 10,802 7,881 4,253 (11,215) Basic earnings (loss) per share $0.89 $0.65 $0.35 $(0.92) Diluted earnings (loss) per share $0.89 $0.65 $0.35 $(0.92) 25 15. Information Concerning Common Stock - (unaudited) The Company's Class A and Class B Common Stock are listed on the American Stock Exchange with the symbols BIO.A and BIO.B, respectively. The following sets forth, for the periods indicated, the high and low prices for the Company's Class A and Class B Common Stock. Class A Class B High Low High Low 2000 First Quarter 33 21.25 33.25 22.63 Second Quarter 27.25 21 28.25 21.50 Third Quarter 25 21 24.25 21.50 Fourth Quarter 34 22.20 33.50 23.88 1999 First Quarter 21.75 18.88 21.38 19.38 Second Quarter 29 20.38 27.50 23.38 Third Quarter 28 25.63 27 25.88 Fourth Quarter 27.50 22.50 27.13 23.13 On February 28, 2001 the Company had 963 holders of record of Class A Common Stock and 250 holders of record of Class B Common Stock. Bio-Rad has never paid a cash dividend and has no present plans to pay cash dividends. 26 REPORT OF INDEPENDENT PUBLIC ACCOUNTANTS To the Stockholders and Board of Directors of Bio-Rad Laboratories, Inc.: We have audited the accompanying consolidated balance sheets of Bio-Rad Laboratories, Inc. (a Delaware Corporation) and subsidiaries as of December 31, 2000 and 1999, and the related consolidated statements of income, cash flows and changes in stockholders' equity for each of the three years in the period ended December 31, 2000. These financial statements are the responsibility of the Company's management. Our responsibility is to express an opinion on these financial statements based on our audits. We conducted our audits in accordance with auditing standards generally accepted in the United States. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement. An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements. An audit also includes assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audits provide a reasonable basis for our opinion. In our opinion, the consolidated financial statements referred to above present fairly, in all material respects, the financial position of Bio-Rad Laboratories, Inc. and subsidiaries as of December 31, 2000 and 1999, and the results of their operations and their cash flows for each of the three years in the period ended December 31, 2000 in conformity with accounting principles generally accepted in the United States. ARTHUR ANDERSEN LLP San Francisco, California February 6, 2001 27 Bio-Rad Laboratories, Inc. Management's Discussion and Analysis ________________________________________________________________ MANAGEMENT'S DISCUSSION AND ANALYSIS OF RESULTS OF OPERATIONS AND FINANCIAL CONDITION This discussion should be read in conjunction with the information contained in the Company's Consolidated Financial Statements and the accompanying notes which are an integral part of the statements. References are to the Notes to Consolidated Financial Statements. The following shows operating income and expense items as a percentage of net sales: Year Ended December 31, 2000 1999 1998 Net sales 100.0 100.0 100.0 Cost of goods sold 47.3 46.0 45.2 Gross profit 52.7 54.0 54.8 Selling, general and administrative expense 34.1 36.0 38.6 Product research and development expense 9.4 9.2 9.2 Purchased in-process research and development - 2.8 - Income from operations 9.2 6.0 7.0 ===== ===== ===== Net income 4.3 2.1 5.4 ===== ===== ===== The year 2000 operations of Bio-Rad Laboratories include a full year's operations of Pasteur Sanofi Diagnostics, S.A. (PSD). The acquisition of PSD was made in October 1999 with the potential benefits of complementary product lines, increased geographic reach and the opportunity to achieve increased operational efficiencies. During the first half of the year 2000, Bio-Rad consolidated selling, marketing and general and administrative operations in Europe and North America. Reductions in both employees and facilities were completed in compliance with legal guidelines in Europe to improve profitability. On August 1, 2000, the Company sold its semiconductor equipment test and manufacturing product line for cash and a note receivable. The cash was used to pay down debt under the senior credit facility. 28 Corporate Results -- Sales, Margins and Expenses Bio-Rad's net sales for 2000 were $725.9 million, an increase of 30.7% over the prior year. The year 2000 was positively impacted by the inclusion of twelve months sales of PSD versus 1999 which included sales for the fourth quarter only. The year 2000 was negatively impacted by a strengthening U.S. dollar, the divestiture of the semiconductor product line and expiration of a distribution agreement. Adjusting for the above significant items, sales growth would have been 8.4% using the 1999 proforma/acquisition sales of $727.9 million and adjusting for currency changes and divested product lines. The Diagnostic segment had growth of 5.4% adjusted for currency, the acquisition of PSD and product line divestitures. Product lines contributing to this growth were Bio-Rad's quality control business, genetic tests and improved penetration for the PSD product line in North America and Asia. The Life Science segment had growth of 17.9% adjusted for currency. The increase reflects increases in the sales of laboratory devices and consumables. Analytical Instrument sales decreased on the divestiture of the semiconductor business as well as a decline in the Company's spectroscopy product lines. Bio-Rad's net sales (sales) in 1999 were $555.4 million, an increase of 24.0% over 1998 sales. Included in the 1999 fourth quarter sales was $60.2 million from the PSD operations (see Note 2). Excluding this amount, Bio-Rad's sales grew by 10.6% over the year 1998. For the year 1999, the impact from currency translation on sales was less than $1.0 million. Excluding any impact from currency for 1999, the Life Science and Clinical Diagnostics segments (excluding the PSD acquisition) grew by 12.2% and 11.6%, respectively. The growth in the Life Science segment is attributable to laboratory products and scientific imaging equipment. The Clinical Diagnostics segment growth was a result of the continuing demand for the Company's diabetes monitoring and quality control systems. Consolidated gross margins in 2000 were 52.7% compared to 54.0% for the year 1999. The inclusion of a full year's operations of the PSD product lines further reduced the Company's margins as these products have overall lower margins than the Company's other Diagnostic products. Excluding PSD, the products of this segment had a decline of 1% on higher manufacturing and service costs. The Life Science segment had no change in gross margin as favorable manufacturing overhead absorption was offset by the negative impact from declining margins on foreign sales. Consolidated gross margins were 54.0% for 1999 compared to 54.8% in the prior year. After adjusting for the acquisition of PSD, gross margins for the businesses operated for full year were 29 55.9%, an improvement over the 54.8% recorded in 1998. The Life Science segment's gross margin improved as sales growth provided the opportunity to lower fixed factory overhead and new product pricing remained firm. The Clinical Diagnostics segment's gross margin experienced no change as pricing pressure in the healthcare industry remained a considerable factor and the cost of foreign sourced products rose as the Yen strengthened when compared to the dollar. The Analytical Instruments segment's gross margin improved as demand increased and pricing improved for the Company's semiconductor test and manufacturing equipment. Consolidated selling, general and administrative expense (SG&A) decreased to 34.1% of sales from 36.0%. For the year 2000, the Company implemented Financial Accounting Standards Board Emerging Issues Task Force Issue 00-10 related to the standardized method for recording shipping and handling charges billed separately to customers. All prior periods presented have been adjusted to consistently apply the gross method. There is no impact on either income from operations or net income in any period presented, only increased sales and increased selling expense. Both the Life Science and Diagnostics segments grew SG&A expense at a rate lower than sales growth. The Analytical Instruments segment had slightly higher SG&A expense on a reduced sales base as declining spectroscopy sales and the divestiture of the semiconductor business did not permit proportional reductions in SG&A without jeopardizing the ongoing business which would further diminish the potential to find suitable strategic options. The Company continues to make the efficient use of SG&A expense a priority. The acquisition of PSD should allow the Company to further leverage this expense in a larger sales environment through the elimination of duplicate facilities and more efficient operations. Consolidated SG&A decreased to 36.0% of sales in 1999 when compared to 38.6% for 1998. After adjustment for the PSD acquisition, SG&A expense for the Company was 36.9%, a decline of 1.7% of sales from the prior year. For the Company excluding PSD, total SG&A grew by less than 60% of sales growth. In absolute dollars, the largest increase in SG&A expense was in the Life Science segment as the Clinical Diagnostics segment grew only slightly and the Analytical Instruments segment declined. Product research and development expense (R&D) increased by 33.1% or $16.9 million, which includes for 2000 a full year's expense associated with the acquired PSD business. As a percentage of sales R&D expense rose to 9.4% of sales from 9.2% in the prior year as both the Life Science and Diagnostics segments have large long term projects with opportunity for substantial future sales and current opportunities including improvements to the existing industrial diagnostic testing product line related to the increased demand for BSE (Bovine Spongiform Encephalopathy or Mad 30 Cow Disease) tests. Expenditure levels as a percentage of sales could rise in 2001 as the longer term projects will not be completed until after 2001. R&D increased by 23.7% in 1999 to $51.2 million including the operations of PSD compared to $41.4 million for the year 1998. Both Life Science and Clinical Diagnostics segments (excluding PSD) increased R&D spending at a rate higher than sales growth as the Company was focusing on R&D programs to increase sales through new product development complementing recent acquisitions. Included in income from operations is the write- off of $15.5 million of "purchased in-process research and development expense" related to the PSD acquisition (IPR&D). IPR&D represents the value assigned in a purchase business combination to research and development projects of the acquired business that have been commenced but not completed at acquisition in accordance with SFAS No. 2, "Accounting for Research and Development Costs". Corporate Results -- Non-Operating Items Interest expense increased substantially for the year 2000 reflecting a full year's cost of borrowed funds to purchase PSD. The Company, in early 2000, replaced the interim $100.0 million Senior Subordinated Credit Facility with a $150.0 million aggregate principal amount of Senior Subordinated Notes due in 2007. The additional capacity was used to reduce the $200.0 million Senior Credit Facility. The Company used a significant portion of the proceeds from the sale of the semiconductor product line to further reduce borrowing under the Senior Credit Facility. At December 31, 2000, the debt to equity ratio was 91% compared to 119% at year end 1999. At this time, no significant asset sales are being considered that would further materially reduce net borrowings and interest expense. Average borrowings for the year 2000 and 1999 were $251.3 and $97.8 million, respectively. Net other income and expense for 2000 includes the gain on sale of assets, amortization of goodwill, non-operating legal costs and settlement costs related to cancelling a financing arrangement (see Note 9). Net other income and expense for 1999 is comprised principally of amortization of goodwill. All years include exchange gains and losses from nonspeculative forward foreign exchange contracts which hedged the exposure of intercompany receivables and payables. The net exchange gain or loss results from the estimating inherent in projecting intercompany balances and transaction charges. Bio-Rad's consolidated effective tax rate was 30%, 29% and 29% in 2000, 1999 and 1998, respectively. The tax rate for all years reflects the utilization of loss carryforwards, foreign sales corporation benefits and foreign tax credits. The effective tax 31 rate in future periods is expected to rise as the deductibility of goodwill amortization and interest expenses, as well as the utilization of loss carryforwards are dependent on the source and amount of income generated by the Company. Financial Condition The Company became substantially leveraged as it entered into expanded credit facilities to acquire PSD. As a result of the debt service obligations undertaken, the Company has a risk of limited liquidity and capital resources. The Company has a Senior Credit Facility of $163.0 million consisting of a $100.0 million revolving facility and a $63.0 million term loan (reduced from $100.0 million initially), allowing for borrowings on a secured basis to September 2004. Additionally, in February 2000, the Company completed the sale of $150.0 million aggregate principal amount of Senior Subordinated Notes due 2007. The lenders have placed restrictions on the Company's ability to: borrow further, service this and other debt, make expenditures for capital improvements, pay dividends, repurchase the Company's own stock and/or make strategic and tactical investments in support of operating the business. The Company is also required to comply with certain financial ratios. The amount of debt undertaken in connection with this acquisition could materially impact the financial condition of the Company should management's plan for operating the new entity not be successful. At December 31, 2000, the Company had available $14.0 million in cash and cash equivalents, $19.1 million under its international lines of credit, and $98.3 million under its principal revolving credit agreement (see Note 5). Management believes that this availability, together with cash flow from operations, will be adequate to meet the Company's current objectives for operations, research and development and investment in our systems and equipment. Net cash provided by operations was $24.2 million, $45.0 million and $27.3 million in 2000, 1999 and 1998, respectively. The largest contributing factor to the decline in net cash provided is increased interest expense on borrowings to purchase PSD. Consolidated net accounts receivable decreased approximately $11.7 million in 2000 when compared to 1999. This decrease is attributable in part to weakening foreign currencies causing a decline in the value of foreign receivables. This decline was offset by increased domestic receivables due to sales increases, the inclusion of PSD ancillary asset sites after January 1, 2000 in Brazil and the Czech Republic, and increased representation in countries with slower payment expectations. Bio-Rad's management 32 regularly reviews the allowance for uncollectible receivables and believes net receivables are fully realizable. For the year ended December 2000, consolidated inventories rose $6.2 million to $132.5 million. The Diagnostic segment had inventory increases related to equipment orders which at year-end 1999 were unfilled due to a short-term supplier problem. Additionally, the inclusion after January 1, 2000 of the ancillary asset sites in Brazil and the Czech Republic added to Diagnostics inventories. The Life Science segment had inventory increases in line with sales activity. The component of inventory at international locations declined as weakened local currencies caused the value of foreign manufactured goods to decline in U.S. dollar terms. Management regularly reviews the impact of obsolescence on current inventory caused by the introduction of new products. Management will continue its focus on inventory control to moderate capital requirements. A valuation reserve is necessary for deferred tax assets (see Note 6) primarily because realization of tax benefits attributable to foreign loss carryforwards is uncertain. Net capital expenditures in 2000 totaled $31.4 million compared to $27.3 million and $21.2 million in 1999 and 1998, respectively. Expenditures in all years include clinical diagnostic equipment placed with customers to be used with the Company's diagnostic reagents. Management regularly approves capital spending in the normal course of business. The Board of Directors authorized the Company to repurchase up to $18 million of the Company's common stock over an indefinite period of time. Through December 2000, the Company has repurchased 583,636 shares of Class A Common Stock and 30,000 shares of Class B Common Stock for a total of $14.5 million. The Company's credit agreements restrict the Company's ability to repurchase its own stock. Share repurchases made during 2000 amounted to $0.4 million. The repurchase is designed to improve shareholder value and to satisfy the Company's obligations under the employee stock purchase and stock option plans. Euro - A New European Currency On January 1, 1999, certain member countries of the European Union entered a three-year transition phase during which the euro was introduced as a common currency in participating countries. The euro is currently used for wholesale financial transactions and will replace the legacy currencies that will be withdrawn between January 1, 2002 and July 1, 2002. This transition will have business implications including the need to adjust internal systems to accommodate the euro and cross-border price transparency. A group of Corporate and 33 European managers have been assigned the task of preparing and accommodating the changes required to continue to do business in the European Union. The Company does not presently expect that the efforts involved will have a material impact on operations, financial position or liquidity. There will be increased competitive pressures, and marketing strategies will need to be continuously evaluated until the transition is complete. As a result of competitive forces and emerging government regulations, the Company cannot guarantee that all problems will be foreseen and remediated, and that no material disruption will occur. Year 2000 From December 31, 1999 continuing through the year 2000, the Company monitored its information centers and operations for transition issues related to the Year 2000. No material problems were reported in any of the Company's facilities or operations during the year. The Company did not experience any material Year 2000 problems with its systems or products, nor did the Company experience any material problems with any of its key customers or suppliers. Financial Risk Management Bio-Rad uses derivative financial instruments to reduce the Company's exposure to fluctuations in foreign exchange rates and, on occasion interest rates. No derivative financial instruments are entered into for the purpose of speculating or trading. Company policy limits all derivative positions exclusively to reducing risk by hedging an underlying economic exposure. In most material cases, derivative investments do not qualify for hedge accounting treatment under Statement of Financial Accounting Standards No. 133, "Accounting for Derivative Instruments and Hedging Activities" ("SFAS 133"). Derivative instruments used in these transactions will be valued at fair value and changes in fair value will be consequently classified into earnings. Bio-Rad operates and conducts business in many foreign countries and is exposed to movements in foreign currency exchange rates. Additionally, Bio-Rad's consolidated net equity is impacted by the conversion of the net assets of international subsidiaries for which the functional currency is not the U.S. dollar. Foreign currency exposures are managed on a centralized basis by the Company's Treasury Department. This allows for the netting of natural offsets and lowers transaction costs and exposures. Bio-Rad currently makes more than 50% of its sales outside the United States and weakening in one currency can often be offset by strengthening in another. Bio-Rad typically enters into forward exchange contracts to sell its foreign currency. Contracts are entered into typically for 34 30 to 60 days, primarily in British Sterling, Japanese Yen, and euros or related currencies. The costs are recognized in income monthly and generally are the reciprocal of the change in underlying assets. Bio-Rad does not hold any derivative contracts that hedge its foreign currency denominated net asset exposures. Bio-Rad uses sensitivity analysis to assess the market risk associated with its foreign currency exchange risk. Market risk is the potential change in fair value of derivative positions from an adverse movement in currency exchange rates. The forward foreign exchange contracts at December 31, 2000 had a net fair value of $34.9 million. A 10% adverse loss on quoted foreign currency exchange rates would result in a $3.5 million loss. This impact of a change in exchange rates, excludes from the analysis the offset derived from the change in the Company's underlying assets and liabilities, which could reduce the effect to zero. The Company's long-term debt consists mostly of fixed rate instruments in order to minimize earnings volatility related to interest expense. While the Company has used derivative instruments in the past, it did not hold any interest rate derivative contracts at December 31, 2000. The current policy is to manage interest costs using a mix of fixed and variable debt. New Financial Accounting Standards In June 1998, the Financial Accounting Standards Board issued SFAS 133. Implementation was then delayed to fiscal years beginning after June 15, 2000. This statement establishes accounting and reporting standards requiring companies to record all derivatives on the balance sheet as either assets or liabilities and measure those instruments at fair value. The manner in which companies are to record gains or losses resulting from changes in the values of those derivatives depends on the use of the derivative and whether it qualifies for hedge accounting. The Company adopted SFAS 133 and subsequent amendments as of the first day of fiscal year 2001 and will currently not seek hedge accounting treatment, instead recording the value adjustment to derivative instruments through earnings. Forward Looking Statements Other than statements of historical fact, statements made in this Annual Report include forward looking statements, such as statements with respect to the Company's future financial performance, operating results, plans and objectives. We have based these forward looking statements on our current expectations and projections about future events. However, actual results may differ materially from those currently anticipated depending on a variety of risk factors including 35 among other things: our ability to successfully integrate with PSD; our substantial leverage and ability to service our debt; our ability to successfully develop and market new products; our reliance on and access to necessary intellectual property; competition in and government regulation of the industries in which we operate; and the monetary policies of various countries. We undertake no obligation to publicly update or revise any forward looking statements, whether as a result of new information, future events, or otherwise. 36