SECURITIES AND EXCHANGE COMMISSION
                         Washington, D.C.  20549
                   __________________________________

                                FORM 10-K

(Mark One)
x   ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES     
     EXCHANGE ACT OF 1934  [FEE REQUIRED]
For the Fiscal Year Ended December 31, 1995

                                   OR

    TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES 
     EXCHANGE ACT OF 1934  [NO FEE REQUIRED]
     For the transition period from _________ to ________


                                              Commission File No. 0-8282

                               OSMONICS, INC.                           
         (Exact name of registrant as specified in its charter)


              Minnesota                               41-0955759        
    (State or other jurisdiction                    (I.R.S. Employer
  of incorporation or organization)               Identification No.)


    5951 Clearwater Drive, Minnetonka, Minnesota              55343      
      (Address of principal executive offices)               (Zip Code)

                             (612) 933-2277         
                     (Registrant's telephone number)

      Securities registered pursuant to Section 12(b) of the Act:

 Common Shares, par value $0.01 per share     New York Stock Exchange    
      (Title of each class)                    (Name of each exchange 
                                               on which registered)

      Securities registered pursuant to Section 12(g) of the Act:

                                  None.

      Indicate by check mark whether the registrant (1) has filed all
reports required to be filed by Section 13 or 15(d) of the Securities
Exchange Act of 1934 during the preceding 12 months (or for such shorter
period that the registrant was required to file such reports), and (2)
has been subject to such filing requirements for the past 90 days.

                  Yes   X                 No      

      Indicate by check mark if disclosure of delinquent filers pursuant
to Item 405 of Regulation S-K is not contained herein, and will not be
contained, to the best of Registrant's knowledge, in definitive proxy or
information statements incorporated by reference in Part III of this
Form 10-K or any amendment to this form 10-K.  [X].

      As of March 1, 1996, 12,802,582 Common Shares were outstanding. 
The aggregate market value of the Common Shares held by non-affiliates
of the Registrant on such date (based upon the closing price of such
shares on the New York Stock Exchange on March 1, 1996) was
$162,774,788.


                   DOCUMENTS INCORPORATED BY REFERENCE

      Portions of the Annual Report to Shareholders for the fiscal year
ended December 31, 1995 (the "Annual Report to Shareholders"), are
incorporated by reference into Parts II and IV.  Portions of the
definitive Proxy Statement for the Annual Meeting of Shareholders to be
held on May 9, 1996 (the "Proxy Statement"), and to be filed within 
120 days after the Registrant's fiscal year ended December 31, 1995, are
incorporated by reference into Part III.


                                 PART II

ITEM 5.  MARKET FOR THE REGISTRANT'S COMMON EQUITY AND RELATED
         SHAREHOLDER MATTERS

COMMON STOCK DATA

The Company's common stock trades on the New York Stock Exchange under
the symbol "OSM".

Shareholders of record on February 22, 1996 numbered 2387.  The Company
estimates that an additional 2500 shareholders own stock held for their 
account at brokerage firms and finanacial institutions.

                            1995                   1994

Quarterly Prices*       High    Low              High    Low  

First Quarter           16 5/8  13 1/4           16 1/8  14 3/8    
Second Quarter          18 1/4  15 1/2           16 5/8  14 1/2
Third Quarter           17 7/8  15 1/2           15 1/2  13 3/4 
Fourth Quarter          21 1/4  16 5/8           15 1/4  13 1/2

* Adjusted for splits

"Notes to Consolidated Financial Statements," pages 19-23 of the Annual Report 
to Shareholders, are incorporated herein by reference.  As of March 14, 1996
there were 2,363 shareholders of record.

The Company has not paid cash dividends on its common shares.  The
Board of Directors currently intends to retain its earnings for the
expansion of the Company's business.  The Company has issued promissory
notes which contain a covenant limiting the payment of dividends to
shareholders.  At December 31, 1995, approximately $24,742,000 of
retained earnings was restricted under this covenant.  

                                 PART IV

ITEM 14.  EXHIBITS, FINANCIAL STATEMENT SCHEDULE, AND REPORTS ON
          FORM 8-K

          (a) (1)  Financial Statement

                   The consolidated financial statements of the
                   Registrant and its subsidiaries, included in the
                   Annual Report to Shareholders, are incorporated by
                   reference in Item 8, and are also incorporated herein
                   by reference.

          (a) (2)  Financial Statement Schedules

                   Reports of Independent Public Accountants on
                   Supplemental Schedules to the Consolidated Financial
                   Statements.

                   Valuation and qualifying accounts.

                   Schedules not listed above have been omitted because
                   they are either not applicable, not material or the
                   required information has been given in the financial
                   statements or in the notes to the financial
                   statements.

                   (3)A.  Certificate of Incorporation of the
                          Registrant, as amended.  (Incorporated herein
                          by reference to Exhibit 3.1 to Registration
                          Statement on Form S-2, File No. 33-336.) 
                          Certificate of Amendment.  (Incorporated
                          herein by reference to Exhibit (3)A on Form
                          10-K for fiscal year ended December 31, 1987,
                          File No. 0-8282.)

                      B.  By-Laws of the Registrant.  (Incorporated
                          herein by reference to Exhibit 3.2 to
                          Registration Statement on Form S-2, File 
                          No. 33-336.)

                   (4)A.  Note Purchase Agreement dated July 12, 1991. 
                          (Incorporated herein by reference to Annual
                          Report on Form 10-K for fiscal year ended
                          December 31, 1991.)

                  (10)A.* 1993 Stock Option Plan and related form of
                          stock option agreement.  (Incorporated herein
                          by reference to Annex C of the Registrant's
                          Joint Proxy Statement/Prospectus dated
                          September 10, 1993.)

                      B.  Stock Option Agreement with Michael L. Snow,
                          Director.  (Incorporated herein by reference
                          to Annual Report on Form 10-K for fiscal year
                          ended December 31, 1993.)

                      C.* 1983 Stock Option Plan and related form of
                          stock option agreement.  (Incorporated herein
                          by reference to Exhibit 10.2 to Registration
                          Statement on Form S-2, File No. 33-336.)

                      D.  1995 Employee Stock Purchase Plan. 
                          (Incorporated herein by reference to the
                          Registrant's Proxy Statement dated 
                          March 27, 1995.)

                      E.* 1995 Director Stock Option Plan. 
                          (Incorporated herein by reference to the
                          Registrant's Proxy Statement dated 
                          March 27, 1995.)

                          * Denotes Executive Compensation Plan.   

                  (13)    1995 Annual Report to Shareholders.  (Only
                          those portions incorporated herein by
                          reference shall be deemed filed with the
                          Commission.)

                  (21)    Subsidiaries of the Registrant.

                  (23)    Consent of Deloitte & Touche LLP.

          (b)      Reports on Form 8-K

                   No reports on Form 8-K were filed during the quarter
                   ended December 31, 1995.

                               SIGNATURES

     Pursuant to the requirements of Section 13 or 15(d) of the
Securities Exchange Act of 1934, the registrant has duly caused this
report to be signed on its behalf by the undersigned, thereunto duly
authorized.

                                    OSMONICS, INC.
                                                                         
                                    By  /s/ D. Dean Spatz              
                                            D. Dean Spatz, President

Dated:  February 28, 1996


     Pursuant to the requirements of the Securities Exchange Act of
1934, this report has been signed below by the following persons on
behalf of the registrant and in the capacities and on the dates
indicated:

       Signatures                  Title                     Date       

 /s/ L. Lee Runzheimer    Chief Financial Officer      February 27, 1996
     L. Lee Runzheimer    and Vice President 
                          Administration (Principal
                          Finance and Accounting Officer)


 /s/ Howard W. Dicke      Vice President Human         February 27, 1996
     Howard W. Dicke      Resources and Corporate 
                          Development, and Treasurer


 /s/ Ruth Carol Spatz     Director                     February 28, 1996
     Ruth Carol Spatz


 /s/ Michael L. Snow      Director                     February 27, 1996
     Michael L. Snow


 /s/ Ralph E. Crump       Director                     February 28, 1996
     Ralph E. Crump


 /s/ Verity C. Smith      Director                     February 28, 1996
     Verity C. Smith


                          Director                     
     Charles W. Palmer


 /s/ D. Dean Spatz        President, Chairman of       February 28, 1996
     D. Dean Spatz        the Board and Director
                          (Principal Executive Officer)