ADDENDUM AND MODIFICATION OF PURCHASE AGREEMENT

This agreement  ("Addendum") is adopted as a modification  and amendment to that
certain Purchase Agreement ("Purchase Agreement") executed as of May 27, 1998 by
and  between  CYPRESS  SPRINGS  LLC,  a  California  limited  liability  company
("Cypress")  managed by Ira E.  Ritter,  an  individual  residing in  California
("Ritter"), and BIOMUNE SYSTEMS, INC., a Nevada corporation ("Biomune").

           A. The parties  desire and intend by this writing to modify and amend
the Purchase Agreement as provided in paragraph 14 of the Purchase Agreement.

           B. The parties  mutually agree that the  modification of the Purchase
Agreement is in the best interests of all parties to the Purchase Agreement.

The Parties, intending to be legally bound, agree as follows:

           1. Effect of  Modification  Agreement.  This  Agreement  modifies the
Purchase Agreement and agreements incorportated therein by reference only to the
extent  expressly  stated  herein.  All  remaining  terms and  conditions of the
Purchase  Agreement  which do not  conflict  with the terms as  modified by this
Agreement  will  continue  in full force and effect.  As used in this  Addendum,
"Purchase Agreement" shall include those incorporated documents.

           2. Changes to  Agreement. The  following  shall apply to the Purchase
Agreement:

                    A. The down  payment to be  credited  against  the  Purchase
               Price  shall be  $360,000,  comprising  the  $360,000  credit for
               amounts paid or advanced under the 1997 purchase transaction.

                    B. Ritter will receive up to 3,750,000 shares of convertible
               preferred  stock of Biomune within two years from the date of the
               Purchase  Agreement  upon  generation  of profits at  Rockwwod of
               $750,000;  provided,  however that if Rockwood has profits during
               such period in an amount that is less than $750,000,  then Ritter
               will receive a portion of such shares  determined by dividing the
               actual  profits by $750,000  and  multiplying  3,750,000  by such
               percentage.

                    C. The right of rescission granted Cypress under Section 2.e
               of the Purchase  Agreement shall be exercisable by Cypress in the
               event  that  Biomune  fails to extend  credit to  Cypress  as the
               parties  may  from  time  to  time  agree,   with  the  following
               consequences  for such  breach:(i)  the down  payment of $360,000
               will be  retained;  (ii) the first  500,000  shares of  preferred
               stock  delivered  as part of the  purchase  price  under 2.B (i),
               above, will be retained; (iii) the note, if any, evidencing prior
               loans to Cypress by Biomune  will be canceled and Cypress will be
               under no  further  obligation  under  such  instrument;  (iv) the
               transfer of the 52% interest to Biomune will be canceled; and (v)
               amounts, if any, outstanding on the Line of Credit referred to in
               the  Purchase  Agreement  will be converted to equity in Rockwood
               equal to a 20% ownership interest.

           3. Remaining  Terms.  Except to the extent modified by this Addendum,
the  remaining  terms and  conditions of the Purchase  Agreemenht  are expressly
accepted and will continue in full force and effect and hereby  incorporated  in
and made a part of this Agrreement by this reference.

IN   WITNESS  WHEREOF,  the   parties  have  executed and  delivered  this as of
August 18, 1998.



                                                    BIOMUNE SYSTEMS, INC.
                                                    a Nevada corporation


                                                    /s/ Michael G. Acton
                                                    ---------------------
                                                    By: Michael G. Acton
                                                    Chief Executive Officer


                                                    CYPRESS SPRINGS LLC

                                                    /s/ Ira E. Ritter
                                                    ---------------------
                                                    By: Ira E. Ritter
                                                    President

                                                    Acknowledged and agreed:

                                                    ROCKWOOD COMPANIES LLC
                                                    a California limited 
                                                    liability company

                                                    /s/ Ira E. Ritter
                                                    ---------------------
                                                    By: Ira E. Ritter
                                                    President