SCHEDULE 14A
                              (Rule 14a-101)
                INFORMATION REQUIRED IN PROXY STATEMENTS

                         SCHEDULE 14A INFORMATION

       PROXY      STATEMENT  PURSUANT TO SECTION 14(a) OF THE  SECURITIES
                  EXCHANGE ACT OF 1934 (AMENDMENT NO. )


  Filed  by  the  Registrant  [ X ]
  Filed  by a  Party  other  than  the Registrant [   ]

  Check the appropriate box:

     [   ]  Preliminary Proxy Statement

     [   ]  Confidential, For Use of the Commission Only (as Permitted
            by Rule 14a-6(e)(2))

     [ X ]  Definitive Proxy Statement

     [   ]  Definitive Additional Materials

     [   ]  Soliciting Material Under Rule 14a-12


                          UNITED-GUARDIAN, INC.
             -----------------------------------------------
             (Name of Registrant as specified in Its Charter)

 -----------------------------------------------------------------------
 (Name of Person(s) Filing Proxy Statement, if Other Than the Registrant)

Payment of Filing Fee (Check the appropriate box):

     [ X ]  No fee required.

     [      ]  Fee  computed  on  table  below  per  Exchange  Act  Rules
            14a-6(i)(1) and 0-11.

            (1)  Title of each class of securities to which transaction
                 applies:

            ---------------------------------------------------------------

            (2)  Aggregate number of securities to which transaction applies:

            ---------------------------------------------------------------

            (3)   Per unit price or other underlying value of transaction
                  computed  pursuant to Exchange Act Rule 0-11 (set forth
                  the amount on which the filing  fee is  calculated  and
                  state how it was determined):

            ---------------------------------------------------------------

            (4)   Proposed maximum aggregate value of transaction:

            ---------------------------------------------------------------

            (5)   Total fee paid:

            ---------------------------------------------------------------

     [ ] Fee paid previously with preliminary materials.

     [      ] Check box if any part of the fee is offset as  provided  by
            Exchange  Act Rule  0-11(a)(2)  and  identify  the filing for
            which the  offsetting fee was paid  previously.  Identify the
            previous filing by registration statement number, or the form
            or schedule and the date of its filing.

            (1)  Amount Previously Paid:

            ---------------------------------------------------------------

            (2)  Form, Schedule or Registration Statement No.:

            ---------------------------------------------------------------

            (3)  Filing Party:

            ---------------------------------------------------------------

            (4)  Date Filed:

            ---------------------------------------------------------------


                         UNITED-GUARDIAN, INC.
       230 Marcus Boulevard - P.O. Box 18050 - Hauppauge, NY 11788

                 NOTICE OF ANNUAL MEETING OF STOCKHOLDERS

                         -----------------------
                         To Be Held May 16, 2001
                         -----------------------


To the Stockholders of UNITED-GUARDIAN, INC.:

     You are hereby notified that the annual meeting of the  stockholders
of UNITED-GUARDIAN, INC., a Delaware corporation (the "Company"), will be
held at the Huntington Hilton Hotel, 598 Broad Hollow Road, Melville,  NY
11747 on  Wednesday,  May 16,  2001 at 10:00  A.M.  local  time,  for the
following purposes:

     1.   To elect  nine (9)  directors  to serve  until the next  annual
          meeting  of  the   stockholders   and  until  their  respective
          successors are elected and qualified;

     2.   To ratify the  selection by the Company of Grant  Thornton LLP,
          independent   certified  public   accountants,   to  audit  the
          financial  statements of the Company for the fiscal year ending
          December 31, 2001; and

     3.   To transact  such other matters as may properly come before the
          meeting or any adjournment thereof.

     Only  stockholders  of record at the close of  business on March 30,
2001 are entitled to notice of and to vote at the meeting.


                                        By order of the Board of Directors
                                        Robert S. Rubinger, Secretary

Dated: April 16, 2001



                            RETURN OF PROXIES

            A Proxy and Business Reply Envelope are enclosed for your use
            if you do not plan to attend the Annual Meeting in person. We
            urge each  stockholder  who is unable  to attend  the  Annual
            Meeting to vote  promptly by signing and returning his or her
            proxy, regardless of the number of shares held.


                           UNITED-GUARDIAN, INC.
        230 Marcus Boulevard - P.O. Box 18050 - Hauppauge, NY 11788
                              (631) 273-0900


                             Proxy Statement

     The  enclosed  proxy  is  solicited  by the  Board of  Directors  of
UNITED-GUARDIAN,  INC. (the  "Company")  for use at the Annual Meeting of
Stockholders (the "Annual Meeting") to be held at 10:00 A.M., local time,
on Wednesday,  May 16, 2001, at the  Huntington  Hilton Hotel,  598 Broad
Hollow Road, Melville, NY 11747, and at any adjournments thereof. A proxy
granted  hereunder  is  revocable at any time before it is voted by (a) a
duly  executed  proxy  bearing a later date,  (b)  written  notice to the
Secretary of the Company  received by the Company at any time before such
proxy is voted at the Annual Meeting,  or (c) revocation in person at the
Annual Meeting.

     It is anticipated  that the mailing of this Proxy  Statement and the
accompanying  Proxy to  Stockholders  will commence on or about April 16,
2001.

                         SOLICITATION OF PROXIES


     The persons named as proxies are Dr. Alfred R. Globus and Kenneth H.
Globus.

     All shares  represented  by  properly  executed,  unrevoked  proxies
received in proper form and in time for use at the Annual Meeting will be
voted in accordance with the directions  specified  thereon and otherwise
in accordance with the judgment of the persons designated as proxies. Any
proxy on which no direction  is  specified  will be voted in the favor of
the nominees to the Board of Directors listed in this Proxy Statement and
in  favor of the  other  proposals  set  forth in the  Notice  of  Annual
Meeting.

     The cost of preparing,  assembling  and mailing the Notice of Annual
Meeting, Proxy Statement,  proxy card and other materials enclosed,  will
be borne by the Company.  In addition to the  solicitation  of proxies by
use of the mails,  officers  and  employees  of the  Company  may solicit
proxies by telephone,  telegram or personal  interview.  The Company will
request brokerage houses and other  custodians,  nominees and fiduciaries
to forward soliciting materials to the beneficial owners of stock held of
record  by such  persons,  and will  reimburse  such  persons  for  their
expenses in forwarding soliciting material.

                  VOTING SECURITIES AND PRINCIPAL STOCKHOLDERS
                  --------------------------------------------

Outstanding Shares And Voting Rights
- ------------------------------------

     Only holders of record of the Company's Common Stock, par value $.10
per share ("Common  Stock"),  at the close of business on March 30, 2001,
will be entitled to notice of and to vote at the Annual Meeting. On March
30, 2001, there were 4,865,839 shares of Common Stock  outstanding.  Each
outstanding share of Common Stock is entitled to one vote on all matters,
which  vote may be given in person or by proxy.  There are no  cumulative
voting rights.

     The nine (9) nominees for director  receiving the greatest number of
votes cast by the holders of Common Stock will be elected directors.

     The  affirmative  vote of the  holders  of a  majority  of shares of
Common Stock  eligible to vote at the Annual Meeting is necessary for the
approval of the proposal to ratify the  selection by the Company of Grant
Thornton  LLP to audit the  financial  statements  of the Company for the
fiscal year ending December 31, 2001.

     Under  Delaware law,  shares as to which a  stockholder  abstains or
withholds  authority  to vote and  shares as to which a broker  indicates
that  it  does  not  have   discretionary   authority  to  vote  ("broker
non-votes")  will be treated as  present  at the Annual  Meeting  for the
purposes of  determining a quorum.  Proxies marked  "Withhold  Authority"
with respect to the election of one or more directors will not be counted
in determining  who are the nine persons who received the greatest number
of votes in the election of  directors.  Proxies  marked  "Abstain"  with
respect to the  ratification  of the  selection of Grant  Thornton LLP to
audit the financial  statements of the Company for the fiscal year ending
December 31, 2001, will have the effect of a vote against ratification.

Principal Stockholders
- ----------------------

     The following  table sets forth the shares of the  Company's  Common
Stock owned  beneficially by each person who, as of March 1, 2001,  owned
of  record  or is known to have  owned  beneficially  more than 5% of the
outstanding Common Stock.

Name and Address
of Beneficial Owner        Amount Beneficially Owned    Percentage of Class
- -------------------        -------------------------    -------------------

Dr. Alfred R. Globus           1,551,326 (1)                   31.7%
26-53 210th Street
Bayside, NY 11360

Kenneth H. Globus                596,053 (2)                   12.2%
19 McCulloch Dr.
Dix Hills, NY 11746

(1) Includes 14,084 shares owned by the Globus  Foundation,  of which Dr.
Globus is  President,  and 882 shares owned by the  University of Science
and Theology, of which he is President and Director.

(2) Includes currently  exercisable  options to purchase 10,000 shares of
Common Stock.

Security Ownership Of Management
- --------------------------------

The  following  information  is  furnished  with  respect to ownership of
shares of Common Stock as of March 1, 2001,  by each  Director and by all
Directors and Officers of the Company as a group (11 persons).  Ownership
of shares by the persons named below  includes sole voting and investment
power held by such persons.

               Name                  Number of Shares     Percent of Class
         --------------------        ----------------     ----------------
         Dr. Alfred R. Globus         1,551,326 (1)               31.7%
         Henry P. Globus                  2,940 (2)                 *
         Benjamin Wm. Mehlman             1,587                     *
         Charles W. Castanza             11,005 (2)                 *
         Robert S. Rubinger              12,037 (2)                 *
         Kenneth H. Globus              596,053 (2)               12.2%
         Alan E. Katz                     6,000                     *
         Lawrence F. Maietta              4,000 (2)                 *
         Arthur Dresner                   7,000 (2)                 *

         All officers and directors
           as a group (11 persons)    2,206,251 (1)(2)            45.0%
* Less than one percent (1%)

     (1)  Includes 14,084 shares owned by the Globus  Foundation of which
          Dr. Globus is President, and 882 shares owned by the University
          of Science and Theology, of which he is President and Director.

     (2)  Includes currently  exercisable  options to purchase the number
          of shares of Common  Stock set forth after each  person's  name
          and all Officers and Directors as a group: Charles W. Castanza-
          10,000; Robert S. Rubinger - 7,000; Kenneth H. Globus - 10,000;
          Henry P. Globus - 2,000;  Lawrence F.  Maietta - 2,000;  Arthur
          Dresner - 2,000;  and all Officers  and  Directors as a group -
          40,000.

                     DIRECTORS AND EXECUTIVE OFFICERS
                     --------------------------------

Nominees For Election As Directors
- ----------------------------------

     Nine  directors  are to be  elected to serve  until the next  Annual
Meeting of Stockholders  and until their successors have been elected and
qualified.  Set  forth in the table  below are the names of all  nominees
designated  by  management  for  election  as  directors,  the  principal
occupation  or  employment  of each nominee for the past five years,  his
present  positions  with the  Company and the year he was first elected a
director.

                                                                      Year First
Name and Position                Principal Occupation During          Elected a
with the Company           Age         the Past Five Years             Director
- ---------------            ---   ---------------------------          ----------

Dr. Alfred R. Globus       80       From July 1988 to date,                1942
C.E.O. and Director                 Chairman of the Board
                                    and C.E.O. of the
                                    Company. For more than
                                    5  years prior thereto,
                                    Chairman of the Board and
                                    President. From February 1982
                                    to November 1997 Chief Financial
                                    Officer of the Company.

Henry P. Globus            78       From July 1988 to date,                1947
Director                            business consultant.
                                    For  more  than  five   years   prior
                                    thereto,  Executive Vice President of
                                    the Company.

Benjamin Wm. Mehlman       90       Retired since February 1999.           1964
Director                            Formerly Counsel to the New York
                                    law firm of Wilfred T. Friedman
                                    P.C., and its predecessor, Friedman
                                    and Shaftan, P.C. for more than
                                    five years prior thereto.

Charles W. Castanza        68       From March 2000 to date, Senior Vice   1982
Senior Vice President               President of the Company. From April
and Director                        1986 to March 2000, Vice
                                    President  of the  Company.  For more
                                    than  five   years   prior   thereto,
                                    Operations  Manager  of  Chemicals  &
                                    Pharmaceuticals for the Company.

Robert S. Rubinger         58       From July 1988 to date, Executive      1982
Secretary, Treasurer and            Vice President and Secretary.  For
Director                            more than five years prior thereto,
                                    Vice President and Secretary of the
                                    Company. Treasurer of the Company
                                    since May 1994.

Kenneth H. Globus          49       From July 1988 to date, President      1984
President, Chief                    and General Counsel of the Company.
Financial Officer                   For more  than 5 years  prior
and Director                        thereto,  Vice  President and
                                    General    Counsel   of   the
                                    Company. Chief Financial Officer
                                    since November 1997.

Alan E. Katz               57       Partner in the law firm of             1994
Director                            Greenfield Stein & Senior, LLP,
                                    New York, NY since 1984.

Lawrence F. Maietta        43       Partner in the accounting firm of      1994
Director                            Bonamasssa & Maietta, CPA's,
                                    Brooklyn, NY, since October 1991. For
                                    more  than  5  years  prior  thereto,
                                    partner  in the  accounting  firm  of
                                    Wilfred Wyler & Co. Controller of the
                                    Company from October 1991 to November
                                    1997.

Arthur Dresner             59       Engaged as "Of Counsel" to the law     1997
Director                            firm of Reed Smith, LLP, New York,
                                    NY (formerly  McAuley Nissen Goldberg
                                    & Hand) since June 1998.  Attorney in
                                    private   practice  and   independent

                                    business   consultant  since  January
                                    1997.  For  more  than 5 years  prior
                                    thereto,    a   Vice   President   in
                                    corporate   development  and  general
                                    management of International Specialty
                                    Products Inc., Wayne, N.J.

     Dr.  Alfred R. Globus and Henry P. Globus are  brothers.  Kenneth H.
Globus is the son of Henry P.  Globus  and the  nephew  of Dr.  Alfred R.
Globus. There are no other family  relationships  between any Director or
Officer of the Company.

Section 16(a) Beneficial Ownership Reporting Compliance
- -------------------------------------------------------

     Section  16(a) of the  Securities  Exchange  Act of 1934 (the "Act")
requires the Company's officers,  directors and persons who own more than
10% of a class of the  Company's  equity  securities  to file  reports of
ownership  and changes in  ownership  with the  Securities  and  Exchange
Commission ("SEC"). Officers, directors and greater than 10% stockholders
are required by SEC regulations to furnish the Company with copies of all
Section  16(a) forms they file.  Based on (i) a review of copies of Forms
3, 4, and 5 and any amendments  thereto furnished to the Company and (ii)
statements  signed  by  each  responsible  person  regarding  his  or her
obligation  to file  Forms 3, 4,  and 5  during  the  fiscal  year  ended
December 31, 2000, the Company  believes that all persons  subject to the
reporting  requirements  pursuant  to Section  16(a)  filed the  required
reports  on a timely  basis  with the SEC  except as  follows:  Alfred R.
Globus failed to file a Form 4 on a timely basis in  connection  with the
disposition  of common  stock in  September  2000.  A Form 5 was filed in
connection with this disposition.

Meetings and Compensation
- -------------------------

     During  the  fiscal  year  ended  December  31,  2000,  the Board of
Directors held four meetings. All Directors attended all of the meetings.

     The Board of  Directors  has an Audit  Committee  to meet and review
with the Company's  independent  auditors the plan,  scope and results of
its  audits.  Members of the Audit  Committee  are Messrs.  Benjamin  Wm.
Mehlman, Alan E. Katz, Lawrence F. Maietta, and Arthur Dresner. There was
one meeting of the Audit Committee  during the fiscal year ended December
31, 2000.  Committee  members receive a fee of $500.00 for attending each
meeting.

     The Board of  Directors  has a Stock  Option  Committee  which meets
periodically  to grant options under the 1993  Employee  Incentive  Stock
Option Plan and the  Non-Statutory  Stock Option Plan For Directors.  The
committee  consists of two  directors.  No fee is paid to such  committee
members.  There were no Stock Option Committee meetings during the fiscal
year ended December 31, 2000.

     The Board of Directors  formed a Compensation  Committee in 1999 for
the purpose of recommending to the Board the  compensation  for corporate
officers for the ensuing year. Members of the Compensation  Committee are
Messrs. Alan E. Katz, Lawrence F. Maietta, and Arthur Dresner. Kenneth H.
Globus serves as advisor to the  Committee  representing  management. The
Committee  held one meeting in 2000.  Commitee  members  receive a fee of
$500.00 for attending each meeting.

     The Board does not have a Nominating Committee.

Audit Committee Report
- ----------------------

     The Audit Committee of the Board of Directors is comprised  of  four
directors:  Benjamin Wm. Mehlman,  Alan E. Katz, Lawrence F. Maietta, and
Arthur Dresner. All of the Audit Committee  members  are  independent  as
that term is defined in Section 121(A) of the  listing  standards  of the
American Stock Exchange.

     The Audit Committee assists the Board of Directors in fulfilling its
oversight   responsibilities  by  reviewing  the  Company's  consolidated
financial reports,  its internal financial and accounting  controls,  and
its auditing,  accounting and financial reporting processes generally. In
May 2000,  the Board of Directors  approved  and adopted a written  Audit
Committee  Charter,  which is attached to this Proxy Statement as Exhibit
A.

     In discharging  its oversight  responsibilities  regarding the audit
process,   the  Audit  Committee   reviewed  and  discussed  the  audited
consolidated  financial  statements of the Company as of and for the year
ended December 31, 2000,  with Company  management and Grant Thornton LLP
("Grant"),  the independent  auditors.  The Audit Committee  received the
written  disclosures  and the letter from Grant required by  Independence
Standards  Board  Standard  No. 1,  Independence  Discussions  with Audit
Committees,  discussed  with Grant any  relationships  which might impair
that firm's  independence  from  management and the Company and satisfied
itself as to the auditors' independence. The Audit Committee reviewed and
discussed with Grant all  communications  required by generally  accepted
auditing  standards,  including  Statement on Auditing  Standards No. 61,
Communications with Audit Committees, as amended.

     Based  upon  these  reviews  and  discussions,  the Audit  Committee
recommended  to  the  Board  of  Directors  that  the  Company's  audited
consolidated  financial  statements be included in the  Company's  Annual
Report on Form  10-KSB for the fiscal  year ended  December  31, 2000 for
filing with the Securities and Exchange Commission.

/s/ Benjamin Wm. Mehlman              /s/ Lawrence F. Maietta
/s/ Alan E. Katz                      /s/ Arthur Dresner

     The foregoing  Audit  Committee  Report shall not be deemed  "filed"
with the Securities and Exchange Commission or subject to the liabilities
of Section 18 of the Securities Exchange Act of 1934.

Principal Accounting Firm Fees
- ------------------------------

     The following table sets forth the aggregate fees, including out-of-
pocket expenses, billed to the Company for the fiscal year ended December
31, 2000 by the Company's principal accountants, Grant Thornton LLP.

     Audit Fees                                $35,000
     Financial Information Systems Design
        and Implementation Fees                $     0 (a)
     All Other Fees                            $ 2,500 (a)
                                               -------
                                               $37,500

(a) The Audit  Committee  has  considered  whether the provision of these
services  is  compatible  with  maintaining  the  principal  accountants'
independence.

COMPENSATION OF DIRECTORS AND EXECUTIVE OFFICERS

Summary Compensation Table
- --------------------------

     The  following  table sets forth for the three years ended  December
31, 2000 certain information  concerning the compensation paid or accrued
to the Chief  Executive  Officer of the Company  and the other  executive
officers of the Company  whose total salary and bonus for the fiscal year
ended December 31, 2000 exceeded $100,000.


                           Annual Compensation                 Long-Term Compensation
                      -----------------------------    ------------------------------------
                                                             Awards               Payouts
                                                       --------------------   ---------------

(a)                   (b)     (c)         (d)    (e)      (f)         (g)        (h)      (i)
                                                Other                Securities           All
Name and                                        Annual   Restricted  Underlying           Other
  Principal                                     Compen-  Stock       Options     LTIP     Compen-
  Position            Year*   Salary     Bonus  sation   Award(s)    /SARs       Payouts  sation
                              ($)         ($)    ($)      ($)         (#)         ($)      ($)
                                                                  
Alfred R. Globus,     1998    $ 97,015    --     -- 1      --         --          --        --
  Chief Executive     1999    $ 98,489   5,000   -- 1      --         --          --        --
  Officer             2000    $122,111   5,000   -- 1      --         --          --        --

Kenneth H. Globus,    1998    $150,196    --     -- 1      --         --          --      $2,947 2
  President           1999    $165,952  15,000   -- 1      --        2,000        --      $3,091 2
                      2000    $179,968  25,000   -- 1      --         --          --      $3,400 2

Robert S. Rubinger,   1998    $102,671    --     -- 1      --         --          --      $2,053 2
  Executive Vice      1999    $108,733   5,000   -- 1      --        2,000        --      $2,275 2
  President           2000    $117,940   7,000   -- 1      --         --          --      $2,412 2

* Year ended on December 31 of such year.

     1    The amount of  personal  benefits received by Alfred R. Globus,
          Kenneth H. Globus and Robert S. Rubinger for these  periods did
          not exceed reporting thresholds.

     2    Under its 401(k)  Plan for all of its  employees,  the  Company
          makes a contribution of up to 2% of each employee's  weekly pay
          for an employee's  elective  deferral of 4% of weekly pay. This
          amount represents the Company's contribution for each year.


Stock Options
- -------------

     During the fiscal year ended  December  31, 2000 the Company did not
grant  Options to purchase  Common Stock under  either the 1993  Employee
Incentive  Stock Option Plan or the  Non-Statutory  Stock Option Plan For
Directors.  The  following  table sets  forth  certain  information  with
respect to options to purchase  Common Stock held on December 31, 2000 by
each of the named executives  officers in the Summary  Compensation table
above.

                                                                 Value of
                   Number of Securities Underlying   Unexercised in-the-Money
                     Unexercised Options/SARs at         Options/SARs at
                        December 31, 2000               December 31, 2000
Name                 Exercisable/Unexercisable       Exercisable/Unexercisable
- ----                 -------------------------       -------------------------

Alfred R. Globus                0/0                             $ 0/0

Kenneth H. Globus           10,000/0                         $41,250/0

Robert S. Rubinger           7,000/0                         $28,875/0


Compensation of Directors
- -------------------------

     Non-officer  directors  receive a fee of $1,000.00  for each meeting
attended. All other directors receive $500.00 for each meeting.

                         APPOINTMENT OF AUDITORS
                         -----------------------

     The  firm  of  Grant  Thornton  LLP,  independent  certified  public
accountants,  of  Melville,  N.Y.,  has  been  selected  by the  Board of
Directors  to be the  independent  auditors of the Company for the fiscal
year ending  December 31, 2001.  The selection of such firm is subject to
ratification  by the  stockholders  at  the  Annual  Meeting.  Management
believes that the firm is well  qualified and  recommends a vote in favor
of the ratification.

     Representatives  of Grant Thornton LLP are expected to be present at
the Annual Meeting and will have an  opportunity to make a statement,  if
they  desire to do so, and will be  available  to respond to  appropriate
questions.

                      ANNUAL REPORT TO STOCKHOLDERS
                      -----------------------------

     The Annual Report to Stockholders for the fiscal year ended December
31, 2000 accompanies this Proxy Statement.

                          STOCKHOLDER PROPOSALS
                          ---------------------

     Proposals of  stockholders  for possible  consideration  at the 2002
Annual Meeting  (expected to be held in May 2002) must be received by the
Secretary  of  the  Company  not  later  than  December  17,  2001  to be
considered  for  inclusion  in the proxy  statement  for that  meeting if
appropriate for consideration under applicable securities laws. The proxy
for the 2002 Annual  Meeting may confer  discretionary  authority  to the
proxy holders for that meeting with respect to voting on any  stockholder
proposal received by the Secretary of the Company after March 2, 2002.

                              OTHER BUSINESS
                              --------------

     Management  of the  Company  knows of no  business  other  than that
referred to in the foregoing Notice of Annual Meeting and Proxy Statement
that may come before the Annual Meeting.

                                       By order of the Board of Directors
                                       Robert S. Rubinger, Secretary

Dated:  April 16, 2001



                          UNITED-GUARDIAN, INC.

        THE COMPANY  WILL  FURNISH,  WITHOUT  CHARGE,  A COPY OF ITS
        ANNUAL  REPORT ON FORM  10-KSB  FOR THE  FISCAL  YEAR  ENDED
        DECEMBER  31,  2000,   INCLUDING  FINANCIAL  STATEMENTS  AND
        FINANCIAL STATEMENT  SCHEDULES,  BUT EXCLUDING EXHIBITS,  TO
        EACH   STOCKHOLDER   WHO  REQUESTS  THE  10-KSB  IN  WRITING
        ADDRESSED  TO  ROBERT  S.  RUBINGER,   CORPORATE  SECRETARY,
        UNITED-GUARDIAN,  INC., P.O. BOX 18050, HAUPPAUGE,  NEW YORK
        11788.


                          UNITED-GUARDIAN, INC.
         230 Marcus Blvd. - P. 0. Box 18050 - Hauppauge, NY 11788

        THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

     The undersigned  hereby appoints Dr. Alfred R. Globus and Kenneth H.
Globus, and each of them, as proxies,  each with the power to appoint his
substitute,  and hereby  authorizes  them to  represent  and to vote,  as
designated below, all the shares of common stock of United-Guardian, Inc.
held of record by the undersigned on March 30, 2001 at the annual meeting

of stockholders to be held on Wednesday,  May 16, 2001,  10:00 a.m. local
time at the  Huntington  Hilton Hotel,  598 Broad Hollow Road,  Melville,
N.Y. 11747, or any adjournment thereof.

1.    ELECTION OF DIRECTORS.
                                   _                                   _
    FOR all nominees listed below |_| WITHHOLD  AUTHORITY to vote for |_|
    (except as marked to the all nominees listed below contrary below)

           (INSTRUCTION: TO WITHHOLD AUTHORITY TO VOTE FOR ANY INDIVIDUAL
             NOMINEE, STRIKE A LINE THROUGH THE NOMINEE'S NAME BELOW.)


     Dr. Alfred R. Globus   Charles W. Castanza    Arthur Dresner
     Henry P. Globus        Robert S. Rubinger     Alan E. Katz
     Benjamin Wm. Mehlman   Kenneth H. Globus      Lawrence F. Maietta

2.    PROPOSAL TO APPROVE THE  APPOINTMENT  OF GRANT  THORNTON LLP AS THE
      INDEPENDENT  PUBLIC  ACCOUNTANTS OF THE COMPANY FOR THE FISCAL YEAR
      ENDING DECEMBER 31, 2001.
                         _                  _                 _
                    FOR |_|        AGAINST |_|       ABSTAIN |_|

      In their  discretion,  the  proxies  are  authorized  to vote  upon
      matters  incident to the conduct of the meeting and upon such other
      business  (which  the Board of  Directors  did not  know,  prior to
      making this  solicitation,  would come  before the  meeting) as may
      properly come before the meeting or any adjournment thereof.

    This  proxy,  when  properly  executed,  will be voted in the  manner
directed herein by the undersigned stockholder.  If no direction is made,
this proxy will be voted FOR proposals 1 and 2.

                                    DATED:___________________________ 2001


                                    --------------------------------------
                                                  Signature

                                    --------------------------------------
                                                  Signature

                                    Please sign  exactly as name  appears
                                    hereon. When shares are held by joint
                                    tenants,   both  should  sign.   When
                                    signing   as   attorney,    executor,
                                    administrator,  trustee or  guardian,
                                    please   give   full   title.   If  a
                                    corporation,   please  sign  in  full
                                    corporate  name by president or other
                                    authorized  officer. If a partnership
                                    please  sign in  partnership  name by
                                    authorized person.

     Please mark,  sign,  date and return the proxy card promptly,  using
the enclosed envelope.

                                Exhibit A
                                ---------

                      CHARTER OF THE AUDIT COMMITTEE
                       OF THE BOARD OF DIRECTORS OF
                          UNITED-GUARDIAN, INC.


1.       Organization

There  shall be a  committee  of the  board  of  directors  ("Board")  of
United-Guardian,  Inc. ("Corporation") to be known as the Audit Committee
("Committee").   The  Committee  shall  be  composed  of  three  or  more
directors, the majority of whom shall be independent of the management of
the Corporation and free of any relationship that, pursuant to applicable
regulations,  or in the opinion of the Board,  would interfere with their
exercise of independent judgment as a Committee member.

2.       Purpose

The  primary  function  of  the  Committee  is to  assist  the  Board  in
fulfilling its oversight responsibilities by reviewing: (a) the financial
reports and other  financial  information  provided by the Corporation to
the  Securities  and  Exchange   Commission  and/or  the  American  Stock
Exchange,  (b) the Corporation's  systems of internal controls  regarding
finance and accounting;  and (c) the Corporation's  auditing,  accounting
and financial  reporting  processes  generally.  The Committee's  primary
duties and responsibilities are to:

     (a) Serve as an  independent  and  objective  party to  monitor  the
Corporation's financial reporting process and internal control system, as
set forth above;

     (b)  Review and  appraise  the audit  efforts  of the  Corporation's
independent auditors; and

     (c)  Encourage  a free and open  means of  communication  among  the
independent  accountants,  the  Corporation's  senior  management and the
Board.

3.       Meetings

The Committee shall meet at least once annually to review the results for
the prior fiscal year, or more frequently as circumstances  require.  The
Committee may ask members of management or others to attend  meetings and
provide  pertinent   information  as  necessary,   possibly  in  separate
executive   sessions  to  discuss  any  matters  that  the  Committee  or
management believes should be discussed privately. In addition, the Chair
of the  Committee  shall  meet in person or by  conference  call with the
independent accountants and management quarterly to review the 10-Q prior
to its  filing  or prior to the  release  of  earnings.  The Chair of the
Committee  shall  then  inform  the  entire  Committee  in  person  or by
conference call of the results of this review.

4.       Responsibilities and Duties

To fulfill its responsibilities and duties the Committee shall:

     (a)  Meet in  person  or by  conference  call  with the  independent
          auditors and senior management of the Corporation to review the
          scope of the proposed  audit for the current year and the audit
          procedures to be utilized;

     (b)  At the conclusion of the audit,  the Committee  shall meet with
          the independent auditors to review:

          (1)  significant  findings  during the year and any comments or
               recommendations of the independent auditors, including the
               status of previous audit recommendations;

          (2)  difficulties  encountered  in the  course  of audit  work,
               including any  restrictions  on the scope of activities or
               access to required information;

          (3)  changes  required  in the  planned  scope of the  internal
               audit plan for the current year;

          (4)  the effectiveness of the accounting and financial controls
               of  the  Corporation  and  any   recommendations   by  the
               independent auditors for the improvement of such controls;
               and

          (5)  the  results  of the  monitoring  of  compliance  with the
               AICPA's Code of Ethical Conduct;

      (c) Review the financial  statements contained in the annual report
          to shareholders with management and the independent auditors to
          determine that the independent  auditors are satisfied with the
          disclosure  and  content  of  the  financial  statements  to be
          presented  to  the  shareholders.  Any  changes  in  accounting
          principles also should be reviewed;

      (d) Provide sufficient  opportunity for the independent auditors to
          meet with the  members  of the  Committee  without  members  of
          management  present.  Among the items to be  discussed in these
          meetings  are  the  independent  auditors'  evaluation  of  the
          Corporations's financial and accounting personnel;

      (e) Submit the  minutes of all  meetings  of the  Committee  to, or
          discuss the matters  discussed at each Committee  meeting with,
          the Board;

      (f) Inquire of management about  significant risks or exposures and
          assess the steps  management has taken to minimize such risk to
          the Corporation;

      (g) Investigate  any  matter  brought to its  attention  within the
          scope of its duties,  with the power to retain outside  counsel
          for this purpose if, in its judgment, that is appropriate; and

      (h) Review  annually,  and if deemed  advisable  by the  Committee,
          amend the Committee's Charter.