1

               UNITED STATES SECURITIES AND EXCHANGE COMMISSION
                          WASHINGTON, DC  20549

                               FORM 10-K

(Mark One)

         X     ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
      -------  SECURITIES EXCHANGE ACT OF 1934 (FEE REQUIRED)
 
               For the Fiscal Year Ended December 31, 1997
- - -----------------------------------------------------------------------------
               TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
      -------  SECURITIES EXCHANGE ACT OF 1934 (NO FEE REQUIRED)
For the transition period from ____________ to ____________

Commission File Number   0-8467
                         ------
                               WESBANCO, INC.
              ----------------------------------------------------
             (Exact name of Registrant as specified in its charter)

     WEST VIRGINIA                                   55-0571723
- - -------------------------------           ---------------------------------
(State or other jurisdiction of           (IRS Employer Identification No.)
incorporation or organization)

     1 Bank Plaza, Wheeling, WV                         26003
- - ----------------------------------------              ----------
(Address of principal executive offices)              (Zip Code)

Registrant's telephone number, including area code:   304-234-9000
                                                      ------------
Securities registered pursuant to Section 12(b) of the Act:  None
                                                             
Securities registered pursuant to Section 12(g) of the Act:

     Title of each class           Name of each Exchange on which registered
- - ------------------------------     -----------------------------------------  
Common Stock $2.0833 Par Value     National Association of Securities 
Nonredeemable Preferred Stock       Dealers, Inc.
                                   None 

Indicate by check mark if disclosure of delinquent filers pursuant to 
Item 405 of Regulation S-K is not contained herein, and will not be 
contained, to the best of registrant's knowledge, in definitive proxy or
information statements incorporated by reference in Part III of this 
Form 10-K or any amendment to this Form 10-K.  _____

Indicate by check mark whether the Registrant (1) has filed all reports 
required to be filed by Section 13 or 15(d) of the Securities Exchange 
Act of 1934 during the preceding 12 months (or for such shorter period that 
the Registrant was required to file such reports), and (2) has been subject 
to such filing requirements for the past 90 days.   Yes    X     No
                                                        -------     ------
The aggregate market value of voting stock computed using the average of the 
bid and ask prices held by non-affiliates of the Registrant on February 27, 
1998 was approximately $405,804,147.

                 (APPLICABLE ONLY TO CORPORATE REGISTRANTS)

As of February 27, 1998, there were 15,964,362 shares of WesBanco, Inc. 
Common stock $2.0833 par value, outstanding.

                    DOCUMENTS INCORPORATED BY REFERENCE

Portions of WesBanco, Inc.'s 1997 Annual Report to Shareholders - Parts II 
and III

Portions of the Registrant's definitive proxy statement to be filed pursuant 
to Regulation 14A not later than 120 days after the end of the fiscal year 
(December 31, 1997) are incorporated by reference in Part III.

                                Page 1 of 64

  2

                                WESBANCO, INC.
                              TABLE OF CONTENTS

ITEM #         ITEM                                                 PAGE(S)
- - ------         ----                                                 ------
               Part I
               ------
    1          Business                                               3-17
    2          Properties                                               18
    3          Legal proceedings                                        18
    4          Submission of matters to a vote of security holders     N/A
          
               Part II
               -------
    5          Market for the registrant's common equity and related
                 stockholder matters                                 19,55
    6          Selected financial data                               45-46 
    7          Management's discussion and analysis of financial
                 condition and results of operations                 46-55
    8          Financial statements and supplementary data           27-44
    9          Changes in and disagreements with accountants on       
                 accounting and financial disclosure                  N/A
      
               Part III
               --------
   10          Directors and Executive Officers of the registrant    19 *
   11          Executive compensation                                  *    
   12          Security ownership of certain beneficial owners and
                 management                                            *
   13          Certain relationships and related transactions          *
          
               Part IV
               -------
   14          Exhibits, financial statement schedules, and reports 
                 on Form 8-K                                           20
  
  
          *    Incorporated by reference to WesBanco, Inc.'s Proxy 
                  Statement dated March 13, 1998, for Annual Meeting of 
                  Stockholders to be held April 15, 1998.

                   This Form contains a total of 64 pages.


  3

PART I

Item 1.  Business
- - -----------------

General
- - -------

     As of December 31, 1997, the Corporation had four banking affiliates 
located in Wheeling, Charleston, Parkersburg, and Fairmont, West Virginia.  
The Registrant had one banking affiliate in Barnesville, Ohio.  WesBanco 
Wheeling has fourteen offices, all in West Virginia, five located in Wheeling, 
two located in Follansbee, three in New Martinsville, one in Sistersville, 
one in Wellsburg and two in Weirton.  WesBanco Barnesville has six offices, 
two located in Barnesville and one each in St. Clairsville, Bethesda, 
Woodsfield and Beallsville, Ohio.  WesBanco Parkersburg has three offices, 
one located in Parkersburg, one located in Elizabeth and one in Mineral Wells.  
WesBanco Charleston has four offices, one located in South Hills, one in South
Charleston, one in Dunbar and one in Sissonville.  WesBanco Fairmont has four 
offices located in Fairmont, five offices located in Morgantown, three offices 
located in Bridgeport, two in Shinnston and one each in Nutter Fort, Kingwood, 
Masontown and Bruceton Mills, West Virginia. The Corporation's mortgage
banking affiliate has offices located in Bridgeport, South Charleston, 
Barboursville, Elkins, Wheeling, and Weirton, West Virginia.  There are
approximately 883 full time equivalent employees employed by all affiliates 
as of December 31, 1997.

     On September 30, 1997, WesBanco and Commercial Bancshares, Incorporated 
jointly announced the signing of a definitive Agreement and Plan of Merger
providing for Commercial, a multibank holding company headquartered in 
Parkersburg, West Virginia, to merge with WesBanco affiliated companies.
Commercial is the bank holding company for seven community banks with 
seventeen offices located in West Virginia and Ohio.  Under the terms 
of the definitive Agreement and Plan of Merger, WesBanco will exchange 2.85 
shares of WesBanco common stock for each share of Commercial common stock
outstanding in a tax free exchange.  The merger, which is based on a fixed 
exchange ratio, will be accounted for as a pooling of interests.  This 
transaction, which is subject to approval by the stockholders of Commercial 
and WesBanco, is expected to be consummated on March 31, 1998.

     WesBanco, Inc., through its subsidiaries, conducts general banking, 
commercial, mortgage banking and trust business.  Its full service banks 
offer a wide range of services to commercial, consumer and government bodies, 
including but not limited to, retail banking services, such as demand, savings
and time deposits; commercial, mortgage, and personal loans; credit card 
services through VISA and MasterCard; personal and corporate trust services 
and discount brokerage services. Most affiliates are participating in local 
partnerships which operate banking machines in those local regions primarily 
under the name of MAC.  The banking machines are linked to CIRRUS, a 
nationwide banking network.

     The Corporation has reported to its shareholders that it may engage in 
other activities of a financial nature authorized by the Federal Reserve Board
through a subsidiary, or through acquisition of established companies.

     As of December 31, 1997, none of the affiliates were engaged in any 
operation in foreign countries and none has had transactions with customers 
in foreign countries.


  4


Item 1.  Business (continued)
- - -----------------------------
General (continued)
- - -------------------

Competition
- - -----------
     Each affiliate bank faces strong competition for local business in 
their respective market areas.  Competition exists for new loans and 
deposits, in the scope and types of services offered, and the interest
rates paid on time deposits and charged on loans, mortgage banking services 
and in other aspects of banking.  The affiliate banks encounter substantial
competition not only from other commercial banks but also from other 
financial institutions.  Savings banks, savings and loan associations, 
brokerage business and credit unions actively compete for deposits.
Such institutions, as well as consumer finance companies, insurance 
companies and other enterprises, are important competitors for various 
types of lending business.  In addition, personal and corporate trust
services and investment counseling services are offered by insurance 
companies, investment counseling firms and other business firms and
individuals.

Supervision and Regulation
- - --------------------------
     As a registered bank holding company, WesBanco is subject to the 
supervision of the Federal Reserve Board and is required to file with 
the Federal Reserve Board reports and other information regarding its 
business operations and the business operations of its subsidiaries.  
WesBanco is also subject to examination by the Federal Reserve Board and 
is required to obtain Federal Reserve Board approval prior to acquiring, 
directly or indirectly, ownership or control of voting shares of any bank, 
if, after such acquisition, it would own or control more than 5% of the 
voting stock of such bank.  In addition, pursuant to federal law and 
regulations promulgated by the Federal Reserve Board, WesBanco may only 
engage in, or own or control companies that engage in, activities deemed by 
the Federal Reserve Board to be so closely related to banking as to be a
proper incident thereto.  Prior to engaging in most new business activities, 
WesBanco must obtain approval from the Federal Reserve Board.

     WesBanco's banking subsidiaries have deposits insured by the Bank 
Insurance Fund ("BIF") of the Federal Deposit Insurance Corporation (the 
"FDIC"), and are subject to supervision, examination and regulation by state 
banking authorities and either the FDIC or the Federal Reserve Board.  In 
addition to the impact of federal and state supervision and regulation, the 
banking subsidiaries of WesBanco are affected significantly by the actions 
of the Federal Reserve Board as it attempts to control the money supply and 
credit availability in order to influence the economy.

     WesBanco's depository institution subsidiaries are subject to affiliate 
transaction restrictions under federal law which limit the transfer of funds 
by the subsidiary banks to their parent and any nonbanking subsidiaries, 
whether in the form of loans, extensions of credit, investments or asset
purchases.  Such transfers by any subsidiary bank to its parent corporation 
or to any nonbanking subsidiary are limited in amount to 10% of the 
institution's capital and surplus and, with respect to such parent and all 
such nonbanking subsidiaries, to an aggregate 20% of any such institution's 
capital and surplus.  Furthermore, such loans and extensions of credit
are required to be secured in specified amounts.


  5

Item 1.  Business (continued)
- - -----------------------------
Supervision and Regulation (continued)
- - --------------------------------------

     The Federal Reserve Board has a policy to the effect that a bank holding 
company is expected to act as a source of financial and managerial strength to 
each of its subsidiary banks and to commit resources to support each such 
subsidiary bank.  Under the source of strength doctrine, the Federal Reserve 
Board may require a bank holding company to make capital injections into a 
troubled subsidiary bank, and may charge the bank holding company with 
engaging in unsafe and unsound practices for failure to commit resources to 
such a subsidiary bank.  This capital injection may be required at times when 
WesBanco may not have the resources to provide it.  Any capital loans by a 
holding company to any of the subsidiary banks are subordinate in right of
payment to deposits and to certain other indebtedness of such subsidiary bank.  
Moreover, in the event of a bank holding company's bankruptcy, any commitment 
by such holding company to a federal bank regulatory agency to maintain the 
capital of a subsidiary bank will be assumed by the bankruptcy trustee and 
entitled to a priority of payment.

     In 1989, the United States Congress passed comprehensive financial 
institutions legislation known as the Financial Institution Reform, Recovery, 
and Enforcement Act ("FIRREA").  FIRREA established a new principal of 
liability on the part of depository institutions insured by the FDIC for any
losses incurred by, or reasonably expected to be incurred by, the FDIC after 
August 9, 1989, in connection with (i) the default of a commonly controlled
FDIC-insured depository institution, or (ii) any assistance provided by the 
FDIC to a commonly controlled FDIC-insured depository institution in danger
of default.  "Default" is defined generally as the appointment of a 
conservator or receiver and "in danger of default" is defined generally 
as the existence of certain conditions indicating that a "default" is likely
to occur in the absence of regulatory assistance.  Accordingly, in the event 
that any insured bank subsidiary of WesBanco causes a loss to the FDIC, other 
bank subsidiaries of WesBanco could be required to compensate the FDIC by 
reimbursing to it the amount of such loss.

Dividend Restrictions
- - ---------------------
     There are statutory limits on the amount of dividends WesBanco's 
depository institution subsidiaries can pay to their parent corporation 
without regulatory approval.  Under applicable federal regulations, 
appropriate bank regulatory agency approval is required if the total of all 
dividends declared by a bank in any calendar year exceeds the available
retained earnings and exceeds the aggregate of the bank's net profits (as 
defined by regulatory agencies) for that year and its retained net profits 
for the preceding two years, less any required transfers to surplus or a 
fund for the retirement of any preferred stock.

FDIC Insurance
- - --------------
     The FDIC has the authority to raise the insurance premiums for 
institutions in the BIF to a level necessary to achieve a target reserve 
level of 1.25% of insured deposits within not more than 15 years.  In
addition, the FDIC has the authority to impose special assessments in 
certain circumstances.  The level of deposit premiums affects the 
profitability of subsidiary banks and thus the potential flow of dividends 
to parent companies.


  6


Item 1.  Business (continued)
- - -----------------------------
     Under the risk-based insurance assessment system that became effective 
January 1, 1994, the FDIC places each insured depository institution in one 
of nine risk categories based on its level of capital and other relevant 
information (such as supervisory evaluations).  Regarding the assessment 
rates under the assessment system, on November 20, 1996, the FDIC voted
to retain the existing Bank Insurance Fund ("BIF") assessment schedule of 
0 to 0.27% (annual rate), and to collect an assessment against BIF assessable 
deposits to be paid to the Financing Corporation ("FICO").  In addition, the 
FDIC eliminated the statutory minimum annual assessment of $2,000. Each
WesBanco Bank was subject to the FICO special assessment at an annual rate 
of 1.29% during 1997. No assessment was paid to the BIF for 1997.

Federal Deposit Insurance Corporation Improvement Act of 1991
- - -------------------------------------------------------------
     In December 1991, Congress enacted the Federal Deposit Insurance 
Corporation Improvement Act of 1991 ("FDICIA"), which substantially 
revised the bank regulatory and funding provisions of the Federal Deposit 
Insurance Act and makes revisions to several other federal banking statutes.

     Among other things, FDICIA requires federal bank regulatory authorities 
to take "prompt corrective action" with respect to depository institutions
that do not meet minimum capital requirements.  For these purposes, FDICIA 
establishes five capital tiers: well capitalized, adequately capitalized,
undercapitalized, significantly undercapitalized and critically 
undercapitalized.

     Rules adopted by the Federal banking agencies under FDICIA provide that 
an institution is deemed to be:  "well capitalized" if the institution has a
total (Tier 1 plus Tier II) risk-based capital ratio of 10.0% or greater, a 
Tier I risk-based ratio of 6.0% or greater, and a leverage ratio of 5.0% or 
greater, and the institution is not subject to an order, written agreement, 
capital directive, or prompt corrective action directive to meet and maintain 
a specific level for any capital measure; "adequately capitalized" if the 
institution has a Total risk-based capital ratio of 8.0% or greater, a Tier I 
risk-based capital ratio of 4.0% or greater, and a leverage ratio of 4.0% or 
greater (or a leverage ratio of 3.0% or greater if the institution is rated 
composite 1 in its most recent report of examination, subject to appropriate 
Federal banking agency guidelines), and the institution does not meet the 
definition of a well-capitalized institution; "undercapitalized" if the 
institution has a Total risk-based capital ratio that is less than 8.0%,
a Tier I risk-based capital ratio that is less than 4.0% or a leverage ratio 
that is less than 4.0% (or a leverage ratio that is less than 3.0% if the 
institution is rated composite 1 in its most recent report of examination, 
subject to appropriate Federal banking agency guidelines) and the institution 
does not meet the definition of a significantly undercapitalized or critically 
undercapitalized institution; "significantly undercapitalized" if the 
institution has a Total risk-based capital ratio that is less than 6.0%, a 
Tier I risk-based capital ratio that is less than 3.0%, or a leverage ratio 
that is less than 3.0% and the institution does not meet the definition of a 
critically undercapitalized institution; and "critically undercapitalized" if 
the institution has a ratio of tangible equity to total assets that is equal 
to or less than 2%.


  7


Item 1.  Business (continued)
- - -----------------------------

     At December 31, 1997, WesBanco and all of its bank subsidiaries qualified 
as well-capitalized based on the ratios and guidelines noted above.  A bank's
capital category, however, is determined solely for the purpose of applying 
the prompt corrective action rules and may not constitute an accurate
representation of that bank's overall financial condition or prospects.

     The appropriate Federal banking agency may, under certain circumstances, 
reclassify a well capitalized insured depository institution as adequately
capitalized.  The appropriate agency is also permitted to require an 
adequately capitalized or undercapitalized institution to comply with the
supervisory provisions as if the institutions were in the next lower category 
(but not treat a significantly undercapitalized institution as critically 
undercapitalized) based on supervisory information other than the capital 
levels of the institution.

     The statute provides that an institution may be reclassified if the 
appropriate Federal banking agency determines (after notice and opportunity 
for bearing) that the institution is in an unsafe and unsound condition or 
deems the institution to be engaging in an unsafe or unsound practice.

     FDICIA generally prohibits a depository institution from making any 
capital distributions (including payment of a dividend) or paying any 
management fee to its holding company if the depository institution would 
thereafter be undercapitalized.  Undercapitalized depository institutions 
are subject to growth limitations and are required to submit a capital 
restoration plan.  The Federal banking agencies may not accept a capital 
restoration plan without determining, among other things, that the plan
is based on realistic assumptions and is likely to succeed in restoring the 
depository institution's capital.  In addition, for a capital restoration 
plan to be acceptable, the depository institution's parent holding company 
must guarantee that the institution will comply with such capital restoration 
plan.  The aggregate liability of the parent holding company is limited to 
the lesser of (i) an amount equal to 5% of the depository institution's total 
assets at the time it became undercapitalized, and (ii) the amount which is 
necessary (or would have been necessary) to bring the institution into 
compliance with all capital standards applicable with respect to such 
institution as of the time it fails to comply with the plan.  If a depository 
institution fails to submit an acceptable plan, it is treated as if it is 
significantly undercapitalized.

     Significantly undercapitalized depository institutions may be subject to 
a number of requirements and restrictions, including orders to sell sufficient 
voting stock to become adequately capitalized, requirements to reduce total 
assets and cessation of receipt of deposits from correspondent banks. 
Critically undercapitalized institutions are subject to the appointment of a 
receiver or conservator.

     FDICIA also contains a variety of other provisions that may affect the 
operation of WesBanco, including reporting requirements, regulatory standards 
for real estate lending, "truth in savings" provisions, and the requirement 
that a depository institution give 90 days' prior notice to customers and
regulatory authorities before closing any branch.


  8


Item 1.  Business (continued)
- - -----------------------------

Capital Requirements
- - --------------------
     The risk-based capital guidelines for bank holding companies and banks 
adopted by the Federal banking agencies were phased in at the end of 1992.  
The minimum ratio of qualifying total capital to risk-weighted assets 
(including certain off-balance sheet items, such as standby letters of credit) 
under the fully phased-in guidelines is 8%.  At least half of the total 
capital is to be comprised of common stock, retained earnings, noncumulative 
perpetual preferred stocks, minority interests and, for bank holding companies, 
a limited amount of qualifying cumulative perpetual preferred stock, less 
goodwill and certain other intangibles ("Tier I capital").  The remainder
("Tier II capital") may consist of other preferred stock, certain other 
instruments, and limited amounts of subordinated debt and the reserve for
credit losses.

     In addition, the Federal Reserve Board has established minimum leverage 
ratio (Tier I capital to total average assets less goodwill and certain other
intangibles) guidelines for bank holding companies and banks.  These 
guidelines provide for a minimum leverage ratio of 3.0% for bank holding 
companies and banks that meet certain specified criteria, including that they 
have the highest regulatory rating.  All other banking organizations are 
required to maintain a leverage ratio of 3.0% plus an additional cushion
of at least 100 to 200 basis points.  The guidelines also provide that 
banking organizations experiencing internal growth or making acquisitions 
will be expected to maintain strong capital positions substantially above 
the minimum supervisory levels, without significant reliance on intangible 
assets.  Furthermore, the guidelines indicate that the Federal Reserve Board 
will continue to consider a "tangible Tier I leverage ratio" in evaluating 
proposals for expansion or new activities.  The tangible Tier I leverage 
ratio is the ratio of Tier I capital, less intangibles not deducted from 
Tier I capital, to total assets, less all intangibles.  Neither WesBanco nor 
any of its bank subsidiaries has been advised of any specific minimum 
leverage ratio applicable to it.
     
     As of December 31, 1997, all of WesBanco's banking subsidiaries had 
capital in excess of all applicable requirements.

Interstate Banking Act
- - ----------------------
     The Riegle-Neal Interstate Banking and Branching Efficiency Act of 
1994 (hereinafter called "Interstate Banking Act") was signed into law by 
President Clinton on September 29, 1994.  The Act generally allows adequately 
capitalized and managed bank holding companies to acquire banks in any state 
starting one year after enactment.  The Act also authorized interstate merger 
transactions effective June 1, 1997.  States are permitted, however, to pass
legislation providing for either earlier approval of mergers with out-of-state 
banks or "opting-out" of interstate mergers entirely.  The Act would permit
banks to acquire branches of out-of-state banks by converting their office 
into branches of the resulting bank.  The Act would also permit banks to 
establish and operate "de novo branches" in any state that "opts-in" to de 
novo branching.  The Act also requires each Federal banking agency to 
prescribe uniform regulations, including guidelines insuring that interstate
branches operated by out-of-state banks are reasonably helping to meet the 
credit needs of communities where they operate.

     WesBanco is incorporated under the laws of the State of West Virginia 
and the West Virginia Legislature adopted substantial amendments to the West
Virginia banking laws in 1996 specifically permitting interstate branching 
under Section 102 and 103 of the Interstate Banking Act, effective May 31, 
1997. The State of Ohio, in which WesBanco has an affiliate bank, enacted 
legislation in 1997 specifically permitting interstate branching.


  9



Item 1.  Business (continued)
- - -----------------------------
Statistical Information
- - -----------------------
     Except as noted, the following statistical data averages included in 
Item I - Business were computed using daily averages for the years ended 
December 31, 1997, 1996 and 1995.  Statistical data not included in 
Item I - Business have been omitted due to inclusion in the 1997 Annual 
Report to Shareholders, incorporated herein by reference, or are not 
applicable.

     The effect on interest income and interest expense for the years ended 
December 31, 1997, 1996 and 1995, due to changes in average volume and rate 
from the prior year, is presented below.  The average volumes and rates are 
shown in the 1997 Annual Report to Shareholders.  The effect of a change
in average volume has been determined by applying the average rate in the 
earlier year to the change in volume.  The change in rate has been determined 
by applying the average volume in the earlier year to the change in rate.  
The change in interest due to both rate and volume has been allocated to 
volume and rate changes in proportion to the relationship of the absolute 
dollar amounts of change in each.  (in thousands):


                                                   1997 Compared to 1996
                                             -------------------------------   
                                                                Net Increase
                                              Volume    Rate     (Decrease)
                                             --------  -------   ------------
Loans                                         $ 8,587   $  431      $ 9,018
Taxable securities                             (1,054)   2,050          996
Tax-exempt securities                           1,014     (182)         832
Federal funds sold                                676       70          746
                                              -------  -------      -------
    Total interest earned                       9,223    2,369       11,592
                                              -------  -------      -------

Interest bearing demand                          (943)   4,363        3,420
Savings deposits                                 (835)    (531)      (1,366)
Certificates of deposit                         3,428    1,316        4,744
Federal funds purchased and
    repurchase agreements                         157      158          315
Other borrowings                                  193      250          443
                                              -------  -------      ------- 
    Total interest paid                         2,000    5,556        7,556
                                              -------  -------      -------
Net Interest Differential                     $ 7,223  $(3,187)     $ 4,036
                                              =======  =======      =======


                                                  1996 Compared to 1995
                                             -------------------------------   
                                                                Net Increase
                                              Volume    Rate     (Decrease)
                                             --------  -------   -----------
Loans                                         $ 7,181  $  (184)     $ 6,997
Taxable securities                             (2,398)     850       (1,548)
Tax-exempt securities                             640     (522)         118
Federal funds sold                               (428)    (283)        (711)
                                              -------   -------   ---------
    Total interest earned                       4,995     (139)       4,856
                                              -------   -------   ---------

Interest bearing demand                          (175)    (697)        (872)
Savings deposits                                 (587)    (929)      (1,516)
Certificates of deposit                         2,944      473        3,417
Federal funds purchased and
    repurchase agreements                         978     (336)         642
Other borrowings                                   65      (88)         (23)
                                               ------   -------   ---------
    Total interest paid                         3,225   (1,577)       1,648
                                               ------   -------   ---------
Net Interest Differential                      $1,770   $1,438       $3,208
                                               ======   =======   =========

  10


Item 1.  Business (continued)
- - -----------------------------
Investment Portfolio
- - --------------------
     The maturity distribution, using book value including accretion of 
discounts and the amortization of premiums and approximate yield of investment 
securities at December 31, 1997, is presented in the following table.  Tax 
equivalent yield basis was not used.  Approximate yield was calculated using 
a weighted average of yield to maturity (in thousands):



                                          
                                                           After One But      After Five But
                                      Within One Year    Within Five Years   Within Ten Years   After Ten Years
                                      ---------------    -----------------   ----------------   ---------------
                                      Amount    Yield    Amount      Yield   Amount     Yield   Amount    Yield
Held to Maturity:                     ------    -----    ------      -----   ------     -----   ------    -----
- - -----------------
                                                                                    
U.S. Treasury and Federal Agency
  securities                          $24,620   6.01%    $42,980      6.19%    ----      ----     ----     ----
States and political
  subdivisions                         14,962   5.14%     54,754      5.07%   $52,896    5.12%   $31,558  5.28%
Other debt securities (1)                 ---    ---         ---       ---        ---     ---      2,277  7.06%
                                      --------------------------------------------------------------------------
Total held to maturity                 39,582   5.68%     97,734      5.56%    52,896    5.12%    33,835  5.40%


Available for Sale: (2)
- - -----------------------
U.S. Treasury and Federal Agency
  securities                           21,681   5.57%     98,382      6.23%    93,996    6.72%       766  7.28%
States and political
  subdivisions                          4,260   3.84%     12,709      4.28%     1,590    4.74%       527  4.65%
Mortgage-backed and other
  securities (1) (3)                   19,699   6.22%     67,106      6.66%    10,299    6.57%     3,206  2.32%
                                      --------------------------------------------------------------------------
Total available for sale               45,640   5.86%    178,197      6.25%   105,885    6.68%     4,499  3.44%
                                      --------------------------------------------------------------------------

Total Investment Securities           $85,222   5.78%   $275,931      6.01%  $158,781    6.16%   $38,334  5.17%
                                      ==========================================================================


(1)  Represents investments with no stated maturity date.
(2)  Average yields on investment securities available for sale have been 
        calculated based on amortized cost.
(3)  Mortgage-backed securities which have prepayment provisions are assigned 
        to maturity categories based on estimated average lives.

  11


Item 1.  Business (continued)
- - -----------------------------
Investment Portfolio (continued)
- - --------------------------------
     Book values of investment securities are as follows (in thousands):


                                                        December 31,
                                             ---------------------------------
                                                  1997      1996       1995
Investments Held to Maturity (at cost):           ----      ----       ----
- - ---------------------------------------  
  U.S. Treasury and Federal
    Agency securities                          $ 67,600   $ 99,457   $219,719
  Obligations of states and
    political subdivisions                      154,170    147,643    129,074
  Other debt securities (1)                       2,277      2,008      1,358
                                               --------   --------   --------
        Total Held to Maturity                  224,047    249,108    350,151
                                               --------   --------   --------
Investments Available for Sale (at market):
- - -------------------------------------------  
  U.S. Treasury and Federal
    Agency securities                           215,908    161,817    157,505
  Obligations of states and
    political subdivisions                       18,994     14,120      5,667
  Mortgage-backed and other securities (2)      107,608    100,264      8,965
                                               --------   --------   --------
        Total Available for Sale                342,510    276,201    172,137
                                               --------   --------   --------
        Total Investments                      $566,557   $525,309   $522,288
                                               ========   ========   ========

 (1) Includes Federal Reserve Bank Stock and Federal Home Loan Bank securities.
 (2) Includes stocks of business corporations.

     There are no issues included in obligations of state and political 
subdivisions which individually or in the aggregate exceed ten percent of 
shareholders' equity as of December 31, 1997.

Loan Portfolio
- - --------------
     Loans outstanding, including loans held for sale, are as follows 
     (in thousands):


                                                  December 31,
                              ------------------------------------------------
                                1997      1996      1995      1994      1993
                                ----      ----      ----      ----      ----
Loans:*
  Commercial                 $206,909   $177,136  $176,809  $170,164  $169,341
  Real Estate--Construction    25,306     21,556    16,544    25,575    21,732
  Real Estate--Mortgage       515,194    510,778   424,917   380,178   356,286
  Personal                    275,305    321,060   284,108   245,032   231,705
                            ---------  ---------  --------  --------  --------
     Subtotal               1,022,714  1,030,530   902,378   820,949   779,064
  Loans Held for Sale          11,705        983         0         0         0
                            ---------  ---------  --------  --------  --------
    Total Loans            $1,034,419 $1,031,513  $902,378  $820,949  $779,064
                            =========  =========  ========  ========  ========

*Gross of allowance for loan losses.  Does not include unearned income on 
 personal loans.



  12


Item 1.  Business (continued)
- - -----------------------------
Loan Portfolio (continued)
- - --------------------------

     WesBanco's real estate-mortgage loans, at 50% of total loans, comprise 
the single largest loan type in the portfolio.  This category consists 
generally of conventional adjustable and fixed rate residential mortgages and 
home equity loans located within the bank's general market areas.  The risks
associated with real estate lending are principally influenced by real 
property values which are affected by the general economic conditions in each 
bank's market areas.

     Loans held for sale consists of residential mortgage loans and are valued 
at the lower of aggregate cost or market value.

     Personal loans represent approximately 27% of total loans and consist 
primarily of indirect vehicle loans originated through automobile dealers and
credit card outstanding balances. These loans are a smaller balance, 
homogeneous group of loans which are not concentrated in a specific market 
area.  Risks in this lending category include the possibility of general 
economic downturn which may cause an increase in credit losses.

     The loan loss policy for consumer installment lending requires a 
charge-off if the loan reaches 120 delinquency days.  Any payments subsequent 
to charge-off are reflected as recoveries.

     Commercial loans, representing 20% of total loans are not concentrated 
in any single industry, but reflect a broad range of business in West Virginia 
and Eastern Ohio.  These loans are predominantly in the manufacturing, 
wholesaling and retail service industries.  The credit risk associated with
commercial lending is principally influenced by general economic conditions 
and the resulting impact on the borrower's operations, mitigated by 
collateral values.

     Each bank within the Corporation has its own renewal policies regarding 
commercial and real estate-construction loans.  However, real estate-
construction loans are generally not renewed at any bank.  Commercial loans
above certain pre-approved dollar limits must be reviewed by the respective 
credit review committee or senior management prior to extension of maturity 
dates or rollover of the loan into a new loan.  Renewals of commercial loans 
below specified lending limitations may be approved by the respective bank 
loan officer.

     The following table presents the approximate maturities of loans other 
than personal loans, residential mortgages, and loans held for sale, 
for all affiliate banks as of December 31, 1997 (in thousands):



                                                 After one
                                   In one       year through       After
                                 year or less    five years      five years
                                 ------------   ------------     ----------
Commercial                          $ 98,862       $ 59,384       $ 48,663
Real estate:
  Construction                         5,395            987         11,784
  Other real estate                   12,084          9,769         63,356
                                   ---------      ---------      ---------
        Total                       $116,341       $ 70,140       $123,803
                                   =========      =========      =========

Fixed rates                         $ 23,380       $ 51,234       $ 39,155
Variable rates                        92,961         18,906         84,648
                                   ---------      ---------      ---------
        Total                       $116,341       $ 70,140       $123,803
                                   =========      =========      =========

  13


Item 1.  Business (continued)
- - -----------------------------
Loan Portfolio (continued)
- - --------------------------
     
     WesBanco banks follow lending policies which require substantial down 
payments along with current market appraisals on the collateral when the 
loans are originated.  The majority of loans are either secured by deeds of 
trust on real property, security agreements on personal property, insurance 
contracts from independent insurance companies or through marketable
securities. WesBanco Bank Wheeling has approximately 42% of consolidated 
gross loans.

     All affiliate banks generally recognize interest income on the accrual 
basis, except for certain loans which are placed on a nonaccrual status, when 
in the opinion of management, doubt exists as to collectability.  All banks 
must conform to the policies of the Board of Governors of the Federal Reserve
System and the Office of the Comptroller of Currency which state that banks 
may not accrue interest on any loan on which either the principal or interest 
is past due 90 days or more unless the loan is both well secured and in the 
process of collection.  When a loan is placed on a nonaccrual status, interest 
income may be recognized as cash payments are received.

     Non-performing assets and secured loans which are in the process of 
collection but are contractually past due 90 days or more as to interest or
principal are as follows (in thousands):


                                                   December 31,
                                   ------------------------------------------
                                   1997      1996     1995     1994      1993
                                   ----      ----     ----     ----      ----
Nonaccrual:
  Personal                       $   61    $   53   $   59   $   12    $  124
  Commercial                      4,662     3,683    3,467    6,766     9,496
  Mortgage                        1,935       928    1,673    1,475     1,620
                                 ------    ------   ------   ------    ------
                                  6,658     4,664    5,199    8,253    11,240
                                 ------    ------   ------   ------    ------
Renegotiated:
  Personal                          --        --         9      --        --
  Commercial                        --      1,527    1,006       23        80
  Mortgage                          773       623       39       81        88
                                 ------    ------   ------   ------    ------
                                    773     2,150    1,054      104       168
                                 ------    ------   ------   ------    ------
Other classified loans: (1)
  Personal                          --        --       --       --       --
  Commercial                      3,765     3,057      341      --       --
  Mortgage                          --        414      697      --       --
                                 ------    ------   ------   ------    ------
                                  3,765     3,471    1,038      --       --
                                 ------    ------   ------   ------    ------
Total non-performing loans       11,196    10,285    7,291    8,357    11,408

Other Real Estate Owned           4,202     3,555    4,137      612       801
                                 ------    ------   ------   ------    ------
  Total non-performing assets   $15,398   $13,840  $11,428   $8,969   $12,209
                                 ======    ======   ======   ======    ======

  14


Item 1.  Business (continued)
- - -----------------------------
Loan Portfolio (continued)
- - --------------------------
                                                   December 31,
                                     ---------------------------------------  
                                     1997    1996     1995     1994     1993
                                     ----    ----     ----     ----     ----
Percentage of non-performing
  assets to loans outstanding         1.5%    1.3%     1.3%     1.1%     1.6%

Past Due 90 Days or More:
  Personal                         $1,379  $1,538   $  863   $  944   $  857
  Commercial                          934   1,294      916      923      754
  Real Estate                         515   1,273    1,255      680    1,131
                                   ------  ------   ------   ------   ------
                                   $2,828  $4,105   $3,034   $2,547   $2,742
                                   ======  ======   ======   ======   ======

(1)  Includes loans internally classified as doubtful and substandard (as 
defined by banking regulations) that meet the definition of impaired loans.

     At December 31, 1997, nonperforming loans, which included all impaired 
loans, totaled $11,196,000, an increase of $911,000 over 1996.  The increase 
was primarily attributable to an increase in nonaccrual commercial and 
commercial real estate loans.  At December 31, 1996 nonperforming loans totaled 
$10,285,000, an increase of $2,994,000 over 1995. The increase was primarily
attributable to a commercial loan which was classified as substandard under 
the definition of an impaired loan. At December 31, 1995, nonaccrual loans
decreased $3,054,000 to $5,199,000, primarily due to the reclassification of 
a commercial real estate loan to other real estate owned.  The action was 
taken on November 1, 1995 by an affiliate through a transfer by deed in-lieu 
of foreclosed commercial property.  Contributing to the increase in 
renegotiated loans during 1995 were certain performing loans classified as
impaired, in accordance with FAS No. 114.  The 1994 decline in nonaccrual 
loans was the result of a commercial real estate loan which was taken off of
nonaccrual status. Nonaccrual loans are generally secured by collateral 
believed to have adequate market values to protect the Corporation from 
significant losses.

     Prior to 1995, loans totaling $3,666,000 which were classified as 
in-substance forcelosures and included in other assets were reclassified to 
loans in accordance with FAS No. 114.  Management continues to monitor 
nonperforming assets to ensure against deterioration in collateral values.


  15


Item 1. Business (continued)
- - ----------------------------
Summary of Loan Loss Experience
- - -------------------------------

     The historical relationship between average loans, loan losses and 
recoveries and the provision for loan losses is presented in the following 
table (in thousands):


                                         For the years ended December 31,
                                    ------------------------------------------
                                     1997     1996     1995     1994    1993
                                     ----     ----     ----     ----    ----
Beginning balance -
  Allowance for loan losses        $15,528  $13,439  $12,960  $12,483  $11,308
  Allowance for loan losses of
    purchased bank                     269      707     ---      ---      ---

Loans charged off:
  Commercial                           950      639    1,263    4,521    1,229
  Real Estate-Mortgage                 254      222      220      524      183
  Personal                           4,288    2,613    1,619    1,003    1,274
                                    ------   ------   ------   ------   ------
      Total loans charged off        5,492    3,474    3,102    6,048    2,686
                                    ------   ------   ------   ------   ------

Recovery of loans previously    
  charged off:
  Commercial                       $   212  $    76  $   377  $   171  $   184
  Real Estate - Mortgage                42       67       97       25       36
  Personal                             658      377      319      256      394
                                   -------  -------  -------  -------  -------
    Total recoveries                   912      520      793      452      614
                                   -------  -------  -------  -------  -------
    Net loans charged off            4,580    2,954    2,309    5,596    2,072
                                   -------  -------  -------  -------  -------
Provision for loan losses            4,314    4,336    2,788    6,073    3,247
Ending balance -                   -------  -------  -------  -------  -------
   Allowance for loan losses       $15,531  $15,528  $13,439  $12,960  $12,483
                                   =======  =======  =======  =======  =======

Ratio of net loans charged off to
    average loans outstanding for
    the period                         .44%     .32%     .27%     .79%     .28%
                                   ========  =======  =======  =======  =======
Ratio of the allowance for loan
    losses to loans outstanding at
    the end of the period             1.50%    1.51%    1.50%    1.61%    1.62%
                                   ========  =======  =======  =======  =======



     The provision for loan losses is based on periodic management evaluation 
of the loan portfolio as well as prevailing and anticipated economic 
conditions, net loans charged off, past loan experience, current delinquency 
factors, changes in the character of the loan portfolio, specific problem 
loans and other factors.  During 1997 and 1996, WesBanco experienced an 
increase in personal loan charge offs.  These increases reflect a rise in 
personal bankruptcies consistent with national trends.


  16

Item 1. Business (continued)
- - ----------------------------
Allocation of the Allowance for Loan Losses
- - -------------------------------------------

     The following represents the allocation of the allowance for loan losses 
     (dollars in thousands):


                                                            December 31,
                           ------------------------------------------------------------------------------
                                 1997           1996            1995            1994            1993
                           -------------   -------------   --------------  --------------  --------------
                                    % of           % of             % of            % of            % of
                           Amount   Loans  Amount  Loans   Amount   Loans  Amount   Loans  Amount   Loans
                           ------   -----  ------  -----   ------   -----  ------   -----  ------   -----  
                                                                             
Specific Allowance:
  Commercial and
    Unallocated            $ 8,404   20%   $ 9,557   17%   $10,480   20%   $10,536   21%   $10,468   22%
  Real Estate-Construction      --    3         --    2         17    2         16    3         16    3
  Real Estate-Mortgage       2,256   50      2,124   50      1,232   47        871   46        750   45
  Personal                   4,871   27      3,847   31      1,710   31      1,537   30      1,249   30
                           -------  ----   -------  ----   -------  ----   -------  ----   -------  ----
    Total                  $15,531  100%   $15,528  100%   $13,439  100%   $12,960  100%   $12,483  100%
                           =======  ====   =======  ====   =======  ====   =======  ====   =======  ====    



     WesBanco has allocated the allowance for loan losses to specific 
portfolio segments based upon historical net charge-off experience, changes 
in the level of non-performing loans, average portfolio growth, local 
economic conditions and management experience.  During 1997, personal loans
as a percentage of total loans decreased as a result of a decline in 
direct auto loan originations, while the increase in specific personal loan
allocations of the allowance reflects an expected continued rise in 
personal bankruptcies.  During 1996, the specific allowance for personal
loans increased due primarily to an increase in outstanding balance and an 
increase in personal bankruptcies.  Management deems the allowance for 
loan losses at December 31, 1997 to be adequate.

Loan Risk Elements
- - ------------------
     
     The Corporation has historically maintained an allowance for loans 
losses which is greater than actual charge-offs.

     Management maintains loan quality through monthly reviews of past due 
loans, and a quarterly review of significant loans which are considered by
affiliate bank personnel to be potential problem loans.  Periodic review of 
significant loans are completed by personnel independent of the loan function.

     There are no significant loans made to customers outside the general 
market area of each affiliate bank.  At times, in order to maintain loan 
volumes, loans are purchased from correspondent banks.  These loans aggregate 
less than $4,500,000 as of December 31, 1997.  Each bank within the 
Corporation follows its usual loan analysis procedures before a determination 
is made to purchase loans from correspondent banks.

     Management's review of the loan portfolio has not indicated any material 
amount of loans, not disclosed in the accompanying tables and discussions 
which are known to have possible credit problems which cause management to 
have serious doubts as to the ability of each borrower to comply with their
present loan repayment terms.

     There were no loan concentrations in excess of 10% of total consolidated 
loans.


  17


Item 1.  Business (continued)
- - -----------------------------
Certificates of Deposit
- - -----------------------

     Maturities of certificates of deposit in denominations of $100,000 or 
more is as follows: (in thousands)

                                              December 31,
                                         ------------------------      
                                            1997          1996
Maturity                                    ----          ----
Under three months                        $25,325       $18,506
Three to six months                        14,593        14,264
Six to twelve months                       19,372        28,762
Over twelve months                         44,322        30,804
                                         --------      --------
Total                                    $103,612       $92,336
                                         ========      ========

     Interest expense on certificates of deposit of $100,000 or more was 
approximately $5,901,000 in 1997, $4,658,000 in 1996, and $4,042,000 in 1995.

Short-Term Borrowings
- - ---------------------

     Securities sold under agreement to repurchase have maturities which range 
between one day and one year.  The following table presents short-term
liabilities (dollars in thousands):


                                         For the years ended December 31,
                                         --------------------------------
                                             1997      1996     1995
                                             ----      ----     ----
Securities sold under agreement
  to repurchase:
Outstanding at year end                    $90,528   $72,587   $70,091
Average daily outstanding                   77,304    69,975    54,791
Maximum outstanding at any month end        90,528    86,854    70,091

Average interest rate:
   During year                                5.00%     4.81%     5.17%
   At year end                                5.62      5.48      5.45
                                                                

Return on Equity and Assets
- - ---------------------------
     
     The following financial ratios are presented:


                                            For the years ended December 31,
                                            --------------------------------
                                                  1997     1996    1995
                                                  ----     ----    ----
Net income to:
  Average total assets                            1.30%    1.34%    1.33%
  Average shareholders' equity                    9.38    10.02    10.15
  Average shareholders' equity and
    redeemable preferred stock                    9.38    10.02    10.07
Dividend payout percentage (cash dividends,
    including those of pooled banks, divided
    by net income)                               56.00    49.76    44.19

Equity to assets (average equity
    divided by average assets)                   13.85    13.33    13.09
Equity and redeemable preferred stock
    to assets (average equity and redeemable
    preferred stock dividend by average assets)  13.85    13.33    13.20


  18



Item 2.  Properties
- - -------------------
     
     The Registrant's affiliates generally own their respective offices, 
related facilities and unimproved real property which is held for future 
expansion.  With certain branch office exceptions, all of the respective 
West Virginia offices are located in downtown Wheeling, Follansbee, Wellsburg,
Weirton, New Martinsville, Sistersville, Elizabeth, Charleston, South 
Charleston, Dunbar, Sissonville, Parkersburg, Kingwood, Fairmont, Morgantown, 
Shinnston, Bridgeport and Masontown.  The Ohio bank offices are located in 
Barnesville, Bethesda, St. Clairsville, Woodsfield and Beallsville. During 
the fourth quarter of 1997, WesBanco acquired property in Charleston, West 
Virginia, where a new office will be constructed to facilitate WesBanco's 
expansion in the downtown area.  Consolidated investment in net bank premises 
and equipment at December 31, 1997 was $34,436,000.
     
     The main office of the Registrant is located at 1 Bank Plaza, Wheeling, 
West Virginia, in a building owned by WesBanco Wheeling.  The building 
contains approximately 100,000 square feet.
     
     At various building locations, WesBanco rents and will continue to look
for opportunities to rent office space to unrelated businesses.  Rental
income generated during 1997 was not considered material.

Item 3.  Legal Proceedings
- - --------------------------

     WesBanco, Inc. and its affiliates are involved in various legal 
proceedings presently pending which are incidental to the business of banking 
in which they are engaged.  These proceedings are pending in various 
jurisdictions in which WesBanco, Inc. and its subsidiaries are engaged in 
business.  Based on the information which has been developed in such
proceedings as of the date hereof, and available to the Corporation, 
management does not believe that any of such proceedings involve claims for 
damages which expose it to a material liability on a consolidated basis.

     The case previously reported in the 1995 Form 10-K, Tankovits v. Glessner, 
et al., Civil Action No. 96-C-59(W) is still pending.  Additional development 
of the facts in the case has failed to disclose any significant actionable 
conduct on the part of the Corporation's subsidiary bank.  Plaintiff has 
initiated some discovery in the case and motions to dismiss the case have 
been filed by all defendants in the proceeding.  While the development of 
the Plaintiff's case is incomplete, and subject to that Contingency, counsel 
has advised the Corporation that the factual allegations contained in the 
Complaint do not appear to provide a basis for recovery by the Plaintiff.


  19



                                    PART II

Item 5. Market for the Registrant's Common Equity and Related 
- - ------------------------------------------------------------- 
 Shareholder Matters
 -------------------
     
     (a)  Approximate Number of Security Holders
     -------------------------------------------
     
     Set forth below is the approximate number of holders of record of the 
Registrant's equity securities as of February 27, 1998.

               Title of Class                        Number
               --------------                        ------
          Common Stock ($2.0833 Par Value)           4,283

     The number of holders listed above does not include WesBanco, Inc. 
employees who have had stock allocated to them through the Corporation's KSOP.
All WesBanco employees who meet the eligibility requirements of the KSOP are
included in the Plan.


                                    PART III

Item 10.  Executive Directors of the Corporation
- - ------------------------------------------------
Name                      Age      Position
- - ----                      ---      ---------
James C. Gardill           51      Chairman of the Board
Robert H. Martin           64      Vice Chairman
Edward M. George           61      President and Chief Executive Officer
Paul M. Limbert            50      Executive Vice President
                                     and Chief Financial Officer
Dennis P. Yaeger           47      Executive Vice President and
                                     Chief Operating Officer
Peter W. Jaworski          42      Senior Vice President-Credit Administration
John W. Moore, Jr.         49      Senior Vice President-Human Resources
Jerome B. Schmitt          48      Senior Vice President-Investments
Edward G. Sloane           59      Vice President-Management Information 
                                     Systems

     Mr. Jaworski was appointed Senior Vice President-Credit Administration of 
the Corporation on January 1, 1998.  Prior to that time, Mr. Jaworski was Vice
President Credit Risk Management of WesBanco Bank Wheeling since July 1997.  
From June 1995 to July 1997, he was Senior Loan Review Officer.  Mr. Jaworski 
joined WesBanco after serving as Senior Vice President and Senior Credit 
Officer of Bank One.

      Mr. Martin was appointed Vice Chairman of the Corporation on February 28, 
1994.  Prior to that time, Mr. Martin was Chairman of the Board of First
Fidelity Bancorp, Inc. since 1986.

     Each of the remaining officers listed above have been an Executive 
Officer of the Corporation or one of its subsidiaries during the past five 
years.


  20


                                   PART IV

Item 14.  Exhibits, financial statement schedules and reports on Form 8-K
- - -------------------------------------------------------------------------
     
     (a)  Certain documents filed as part of the Form 10-K        
     -----------------------------------------------------        Page(s)
                                                                  -------
     
     (1)  Consolidated Balance Sheet as of December 31,             27
          1997 and 1996.
          
          Consolidated Statements of Income for the years           28
          ended December 31, 1997, 1996 and 1995.
          
          Consolidated Statements of Changes in Shareholders'       29
          Equity for the years ended December 31, 1997,
          1996 and 1995.
          
          Consolidated Statement of Cash Flows for the years        30
          ended December 31, 1997, 1996 and 1995.
          
          Notes to Consolidated Financial Statements             31-43
          
          Report of Ernst & Young LLP, Independent Auditors         44
     
     (b)  Reports on Form 8-K
     ------------------------
     No reports of Form 8K were filed during the quarter ended 
      December 31, 1997.



  21


Item 14.  Exhibits, financial statement schedules and reports on Form 8-K 
- - ------------------------------------------------------------------------- 
 (continued)
 -----------

Exhibit             Title                                            Page(s)
- - -------             -----                                            -------
  3.1        Articles of Incorporation of WesBanco, Inc., restated      *
             as of November 17, 1995 (1)
  
  3.2        Bylaws of WesBanco, Inc. (1)                               *
  
  4          Specimen Certificate of WesBanco, Inc. Common Stock (2)    *

 10.1        The Stock Option Agreement By and Between WesBanco, Inc.   *
             and Commercial Bancshares, Incorporated, dated 
             September 12, 1997 (7)                                     

 10.2        The Restated WesBanco Directors' Deferred Compensation     *
             Plan Effective December 15, 1994 (1)                       

 10.3        Employment Agreement Between Robert H. Martin, First       *
             National Bank in Fairmont and WesBanco dated 
             February 28, 1994 (4)                                      

 10.4        Employment Agreement Between Ernest S. Fragale, WesBanco   *
             Mortgage Company and WesBanco, Inc. dated the 20th Day of
             August, 1996 (5)                                           

 10.5        Employment Agreement Between Frank R. Kerekes, First       *
             National Bank in Fairmont and WesBanco, dated February 28, 
             1994 (4)                                                   
 
 10.6        Employment Agreement Effective January 1, 1993, By and     *
             Between Edward M. George, WesBanco and WesBanco Bank 
             Wheeling (4)                                               

 10.7        Employment Agreement Effective January 1, 1993, By         *
             and Between Paul M. Limbert, WesBanco and WesBanco Bank 
             Wheeling (4)                                               

 10.8        Employment Agreement Effective January 1, 1993, By and     *
             Between Dennis P. Yeager, WesBanco and WesBanco Bank 
             Wheeling (4)                                               

 10.9        Employment Agreement Effective January 1, 1993, By and     *
             Between Jerome B. Schmitt, WesBanco and WesBanco Bank 
             Wheeling (4)                                               

 10.10       Employment Agreement Effective December 2, 1991, By and    *
             Between Stephen F. Decker, Albright National Bank of 
             Kingwood, and WesBanco (4)                                 

 10.11       Employment Agreement Effective December 2, 1991, By and    *
             Between Rudy F. Torjak, Albright National Bank of 
             Kingwood, and WesBanco (4)                                 

 10.12       Employment Agreement Effective December 1, 1993, By and    *
             Between Thomas L. Jones, WesBanco and WesBanco Bank South 
             Hills (4)                                                  

 10.13       Employment Agreement Effective December 1, 1993, By and    *
             Between John W. Moore, Jr., WesBanco and WesBanco Bank 
             Wheeling (4)                                               


  22


Item 14.  Exhibits, financial statement schedules and reports on Form 8-K 
- - -------------------------------------------------------------------------
(continued)
- - -----------

Exhibit             Title                                            Page(s)
- - -------             -----                                            -------
 10.14       Employment Agreement By and Between The National Bank of   *
             West Virginia, WesBanco, Inc., and C. Barton Loar dated
             December 30, 1996 (5)                                      

 10.15       Employment Agreement By and Between Brenda H. Robertson,   *
             WesBanco Bank South Hills and WesBanco and dated as of 
             June 30, 1997 (6)                                          

 11          Computation of Earnings Per Share                         25

 12          Ratio of Earnings to Combined Fixed Charges and           26
             Preferred Stock Dividends

 13          1997 Annual Report to Shareholders                     27-55
             The Consolidated Financial Statements, together
             with the report thereon of Ernst & Young LLP dated 
             February 4, 1998, Management Discussion and Analysis 
             of the Consolidated Financial Statements included in 
             the accompanying 1997 Annual Report to Shareholders
             are incorporated herein by reference.  With the
             exception of the aforementioned information, the 1997 
             Annual Report is not to be deemed filed as part of this 
             report.  Financial statement schedules not included in 
             this Form 10-K Annual Report have been omitted because 
             they are not applicable or the required information is 
             shown in the Financial Statements or notes thereto.

 21          Subsidiaries of the Registrant                            56
                                                                      
 22          Proxy Statement for the Annual Shareholders' meeting       *
             held April 15, 1998 (3)

 23.1        Consent of Ernst & Young LLP                              57

 23.2        Consent of Price Waterhouse LLP                           58

 24          Power of Attorney                                      59-61

 27          Financial Data Schedule                                   64

 99.1        Report of Price Waterhouse LLP dated January 25,          62
             1996, except as to the pooling-of-interests with 
             Bank of Weirton which is as of August 30, 1996, on 
             WesBanco, Inc. Consolidated Financial Statements as 
             of December 31, 1995 and for the year then ended 
             December 31, 1995

 99.2        Report of Grant Thornton LLP dated October 17, 1996,      63    
             on Bank of Weirton Financial Statements as of 
             December 31, 1995 and for the year then ended
             December 31, 1995, not presented separately herein.


  23


Item 14.  Exhibits, financial statement schedules and reports on Form 8-K 
- - -------------------------------------------------------------------------
(continued)
- - -----------

*      Indicates document incorporated by reference.

(1)    This exhibit is being incorporated by reference with respect to a 
       prior Registration Statement filed by the Registrant on Form S-4 
       under Registration No. 333-3905 which was filed with the Securities 
       and Exchange Commission on June 20, 1996.
(2)    This exhibit is being incorporated by reference with respect to a 
       prior Registration Statement filed by the Registrant on Form S-4 
       under Registration No. 33-42157 which was filed with the Securities
       and Exchange Commission on August 9, 1991.
(3)    This exhibit is being incorporated by reference with respect to a 
       Schedule 14A, Definitive Proxy Statement, which was filed by the 
       Registrant with the Securities and Exchange Commission on March 13, 
       1998.
(4)    This exhibit is being incorporated by reference with respect to a 
       prior Registration Statement filed by the Registrant on Form S-4 
       under Registration No. 33-72228 which was filed with the Securities 
       and Exchange Commission on November 30, 1993.
(5)    This exhibit is being incorporated by reference with respect to a 
       prior Registration Statement filed by the Registrant on Form S-4 
       under Registration No. 333-11461 which was filed with the Securities
       and Exchange Commission on November 6, 1996.
(6)    This exhibit is being incorporated by reference with respect to a 
       prior Registration Statement filed by the Registrant on Form S-4 
       under Registration No. 333-24171 which was filed with the Securities
       and Exchange Commission on April 25, 1997.
(7)    Incorporated by reference to a schedule 13D filed by WesBanco with 
       the Securities and Exchange Commission on September 22, 1997.



  24


                                 SIGNATURES

     Pursuant to the Requirements of Section 13 or 15(d) of the Securities 
Exchange Act of 1934, the Registrant has duly caused this report to be signed 
on its behalf by the undersigned, thereunto duly authorized, on March 13, 1998.

                                              WESBANCO, INC.
                                              
                                              By: /s/ Edward M. George 
                                                 __________________________
                                                  Edward M. George
                                                  President and Chief
                                                  Executive Officer


                                              By: /s/ Paul M. Limbert
                                                 __________________________
                                                  Paul M. Limbert
                                                  Executive Vice President
                                                  and Chief Financial Officer

     Pursuant to the requirements of the Securities Exchange Act of 1934, this 
report has been signed below by the following persons on behalf of the 
registrant and in the capacities indicated, on March 13, 1998.


                                              By: /s/ James C. Gardill
                                                 __________________________
                                                  James C. Gardill
                                                  Chairman of the Board

     The Directors of WesBanco (listed below) executed a power of attorney 
appointing James C. Gardill their attorney-in-fact, empowering him to sign 
this report on their behalf.

James E. Altmeyer
Earl C. Atkins
Ray A. Byrd
R. Peterson Chalfant
Christopher V. Criss
James D. Entress
Ernest S. Fragale
James C. Gardill
Edward M. George
                                              By: /s/James C. Gardill 
John W. Kepner                                   ___________________________  
Frank R. Kerekes                                  James C. Gardill     
Robert H. Martin                                  Attorney-in-fact
Eric Nelson                              
Melvin C. Snyder, Jr.                     
Joan C. Stamp
Carter W. Strauss
Reed J. Tanner
J. Christopher Thomas
John A. Welty
William E. Witschey