EXHIBIT 4.9

                 CORPORATE COMMERCIAL PAPER - MASTER NOTE
                 BETWEEN AND AMONG AMGEN INC., AS ISSUER,
          CEDE & CO., AS NOMINEE OF THE DEPOSITORY TRUST COMPANY
                    AND CITIBANK, N.A. AS PAYING AGENT



                                                        Date of Issuance


       AMGEN INC. (Issuer), for value received, hereby promises to pay
  Cede & Co., as nominee of The Depository Trust Company, or to
  registered assigns: (i) the principal amount, together with unpaid
  accrued interest thereon, if any, on the maturity date of each
  obligation identified on the records of Issuer (the Underlying
  Records) as being evidenced by this Master Note, which Underlying
  Records are maintained by CITIBANK, N.A. (Paying Agent); (ii)
  interest on the principal amount of each such obligation that is
  payable in installments, if any, on the due date of each installment,
  as specified on the Underlying Records; and (iii) the principal
  amount of each such obligation that is payable in installments, if
  any, on the due date of each installment, as specified on the
  Underlying Records.  Interest shall be calculated at the rate and
  according to the calculation convention specified on the Underlying
  Records.  Payments shall be made by wire transfer to the registered
  owner from Paying Agent without the necessity of presentation and
  surrender of this Master Note.

       REFERENCE IS HEREBY MADE TO THE FURTHER PROVISIONS OF THIS
  MASTER NOTE SET FORTH ON THE REVERSE HEREOF.

       This Master Note is a valid and binding obligation of Issuer.

  Not Valid Unless Countersigned for Authentication by Paying Agent.


       CITIBANK, N.A.                     AMGEN INC.


       By: /s/ Wafaa Orfy                 By: /s/Larry A. May
           Authorized Countersignature         Authorized Signature


                                          Guarantor

                                          By: /s/
                                               Authorized Signature




  

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  At the request of the registered owner, Issuer shall promptly issue
  and deliver one or more separate note certificates evidencing each
  obligation evidenced by this Master Note.  As of the date any such
  note certificate or certificates are issued, the obligations which
  are evidenced thereby shall no longer be evidenced by this Master
  Note.

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       FOR VALUE RECEIVED, the undersigned hereby sells, assigns, and
  transfers unto

  (Name, address and Taxpayer Identification Number of Assignee)

  the Master Note and all rights thereunder, hereby irrevocably
  constituting and appointing attorney to transfer said Master Note on
  the books of Issuer with full power of substitution in the premises.


  Dated:

  Signature(s) Guaranteed:                     (Signature)

  Notice:  The Signature on this assignment must correspond with the
  name as written upon the face of this Master Note, in every
  particular, without alteration or enlargement or any change
  whatsoever.

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       Unless this certificate is presented by an authorized
  representative of The Depository Trust Company, a New York
  corporation (DTC), to Issuer or its agent for registration of
  transfer, exchange, or payment, and any certificate issued is
  registered in the name of Cede & Co. or in such other name as is
  requested by an authorized representative of DTC (and any payment is
  made to Cede & Co. or to such other entity as is requested by an
  authorized representative of DTC), ANY TRANSFER, PLEDGE, OR OTHER USE
  HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL
  inasmuch as the registered owner hereof, Cede & Co., has an interest
  herein.

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                            FORM OF LEGEND FOR
                  PRIVATE PLACEMENT MEMORANDUM AND NOTES


  THE NOTES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933,
  AS AMENDED (THE ACT), OR ANY OTHER APPLICABLE SECURITIES LAW, AND
  OFFERS AND SALES THEREOF MAY BE MADE ONLY IN COMPLIANCE WITH AN
  APPLICABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE ACT
  AND ANY APPLICABLE STATE SECURITIES LAWS.  BY ITS ACCEPTANCE OF A
  NOTE, THE PURCHASER WILL BE DEEMED TO REPRESENT THAT IT HAS BEEN
  AFFORDED AN OPPORTUNITY TO INVESTIGATE MATTERS RELATING TO THE ISSUER
  AND THE NOTES, THAT IT IS NOT ACQUIRING SUCH NOTE WITH A VIEW TO ANY
  DISTRIBUTION THEREOF AND THAT IT IS EITHER (A) AN INSTITUTIONAL
  INVESTOR OR SOPHISTICATED INDIVIDUAL INVESTOR THAT IS AN ACCREDITED
  INVESTOR WITHIN THE MEANING OF RULE 501(a) UNDER THE ACT (AN
  INSTITUTIONAL ACCREDITED INVESTOR OR SOPHISTICATED INDIVIDUAL


  ACCREDITED INVESTOR, RESPECTIVELY) AND THAT EITHER IS PURCHASING
  NOTES FOR ITS OWN ACCOUNT, IS A U.S. BANK (AS DEFINED IN SECTION
  3(a)(2) OF THE ACT) OR A SAVINGS AND LOAN ASSOCIATION OR OTHER
  INSTITUTION (AS DEFINED IN SECTION 3(a)(5)(a) OF THE ACT) ACTING IN
  ITS INDIVIDUAL OR FIDUCIARY CAPACITY OR IS A FIDUCIARY OR AGENT
  (OTHER THAN A U.S. BANK OR SAVINGS AND LOAN) PURCHASING NOTES FOR ONE
  OR MORE ACCOUNTS EACH OF WHICH IS SUCH AN INSTITUTIONAL ACCREDITED
  INVESTOR OR SOPHISTICATED INDIVIDUAL ACCREDITED INVESTOR (i) WHICH
  ITSELF POSSESSES SUCH KNOWLEDGE AND EXPERIENCE OR (ii) WITH RESPECT
  TO WHICH SUCH PURCHASER HAS SOLE INVESTMENT DISCRETION; OR (B) A
  QUALIFIED INSTITUTIONAL BUYER (QIB) WITHIN THE MEANING OF RULE 144A
  UNDER THE ACT WHICH IS ACQUIRING NOTES FOR ITS OWN ACCOUNT OR FOR ONE
  OR MORE ACCOUNTS, EACH OF WHICH IS A QIB AND WITH RESPECT TO EACH OF
  WHICH THE PURCHASER HAS SOLE INVESTMENT DISCRETION; AND THE PURCHASER
  ACKNOWLEDGES THAT IT IS AWARE THAT THE SELLER MAY RELY UPON THE
  EXEMPTION FROM THE REGISTRATION PROVISIONS OF SECTION 5 OF THE ACT
  PROVIDED BY RULE 144A.  BY ITS ACCEPTANCE OF A NOTE, THE PURCHASER
  THEREOF ALSO SHALL ALSO BE DEEMED TO AGREE THAT ANY RESALE OR OTHER
  TRANSFER THEREOF WILL BE MADE ONLY (A) IN A TRANSACTION EXEMPT FROM
  REGISTRATION UNDER THE ACT, EITHER (1) TO THE ISSUER OR TO GOLDMAN,
  SACHS & CO. OR ANOTHER PERSON DESIGNATED BY THE ISSUER AS A PLACEMENT
  AGENT FOR THE NOTES (COLLECTIVELY, THE PLACEMENT AGENTS), NONE OF
  WHICH SHALL HAVE ANY OBLIGATION TO ACQUIRE SUCH NOTE, (2) THROUGH A
  PLACEMENT AGENT TO AN INSTITUTIONAL ACCREDITED INVESTOR,
  SOPHISTICATED INDIVIDUAL ACCREDITED INVESTOR OR A QIB, OR (3) TO A
  QIB IN A TRANSACTION THAT MEETS THE REQUIREMENTS OF RULE 144A AND (B)
  IN MINIMUM AMOUNTS OF $250,000.

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