EXHIBIT 10.8 January 5, 1998 Dr. Ralph W.F. Hardy PO Box 509 Clarence Center, NY 14032 Dear Dr. Hardy: By this letter agreement, BioTechnica would like to amend your Consulting Agreement dated November 27, 1996, as follows: 2. Term; Payment Upon Termination (a) The term of this Agreement shall commence on January 1, 1998, and shall terminate on the earlier of the death of the Consultant or on December 31, 1998 (the "Expiration Date"). If the provisions of this letter are in accordance with your understanding, please sign and return one of the enclosed copies. Very truly yours, /s/ Bruno Carette President /s/ Ralph W.F. Hardy January 5, 1998 Ralph W.F. Hardy Date