Exhibit 99.1






                            CERTIFICATION PURSUANT TO
                             18 U.S.C. SECTION 1350,
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002


In connection with the Quarterly  Report of Cytogen  Corporation (the "Company")
on Form  10-Q  for the  period  ended  September  30,  2002 as  filed  with  the
Securities and Exchange Commission on the date hereof (the "Report"),  H. Joseph
Reiser,  President and Chief Executive Officer of the Company, hereby certifies,
pursuant to 18 U.S.C.  Section 1350,  as adopted  pursuant to Section 906 of the
Sarbanes-Oxley Act of 2002, that:

     (1)  The Report fully  complies with the  requirements  of section 13(a) or
          15(d) of the Securities Exchange Act of 1934; and

     (2)  The  information  contained  in the  Report  fairly  presents,  in all
          materials  respects,  the financial condition and result of operations
          of the Company.





November 13, 2002                   /s/ H. Joseph Reiser
                                    -------------------------------------
                                    H. Joseph Reiser
                                    President and Chief Executive Officer