Exhibit 32.1


                CERTIFICATION PURSUANT TO 18 U.S.C. SECTION 1350,

                             AS ADOPTED PURSUANT TO

                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002



         In  connection   with  the  Annual  Report  on  Form  10-K/A (Amendment
No. 2) of Cytogen  Corporation  (the  "Company") for the year ended December 31,
2002 as filed with the  Securities  and Exchange  Commission  on the date hereof
(the  "Report"),  the  undersigned,  Michael  D.  Becker,  President  and  Chief
Executive  Officer  of the  Company,  hereby  certifies,  pursuant  to 18 U.S.C.
Section 1350, that:

         (1) The Report fully complies with the requirements of Section 13(a) or
15(d) of the Securities Exchange Act of 1934; and

         (2) The  information  contained in the Report fairly  presents,  in all
material  respects,  the  financial  condition  and results of operations of the
Company.

         A signed original of this written statement required by Section 906 has
been  provided to the Company and will be retained by the Company and  furnished
to the Securities and Exchange Commission or its staff upon request.



                                     /s/ Michael D. Becker
                                     --------------------------------------
Dated:  September 19, 2003           Michael D. Becker
                                     President and Chief Executive Officer