<ARTICLE>                     9
<CIK>                         0000741516
<NAME>                        American National Bankshares Inc.
<MULTIPLIER>                  1000

                                              
<PERIOD-TYPE>                          3-MOS        YEAR
<FISCAL-YEAR-END>                      DEC-31-2000  DEC-31-2000
<PERIOD-START>                         JAN-01-2000  JAN-01-2000
<PERIOD-END>                           MAR-31-2000  MAR-31-2000
<CASH>                                     14,267     14,267
<INT-BEARING-DEPOSITS>                      1,806      1,806
<FED-FUNDS-SOLD>                                0          0
<TRADING-ASSETS>                                0          0
<INVESTMENTS-HELD-FOR-SALE>               127,073    127,073
<INVESTMENTS-CARRYING>                     44,035     44,035
<INVESTMENTS-MARKET>                       43,142     43,142
<LOANS>                                   302,424    302,424
<ALLOWANCE>                                 4,286      4,286
<TOTAL-ASSETS>                            504,229    504,229
<DEPOSITS>                                397,061    397,061
<SHORT-TERM>                               24,619     24,619
<LIABILITIES-OTHER>                         3,934      3,934
<LONG-TERM>                                21,000     21,000
<PREFERRED-MANDATORY>                           0          0
<PREFERRED>                                     0          0
<COMMON>                                    6,104      6,104
<OTHER-SE>                                 51,511     51,511
<TOTAL-LIABILITIES-AND-EQUITY>            504,229    504,229
<INTEREST-LOAN>                             6,436      6,436
<INTEREST-INVEST>                           2,579      2,579
<INTEREST-OTHER>                               52         52
<INTEREST-TOTAL>                            9,067      9,067
<INTEREST-DEPOSIT>                          3,399      3,399
<INTEREST-EXPENSE>                          3,950      3,950
<INTEREST-INCOME-NET>                       5,117      5,117
<LOAN-LOSSES>                                 215        215
<SECURITIES-GAINS>                              0          0
<EXPENSE-OTHER>                             3,123      3,123
<INCOME-PRETAX>                             2,954      2,954
<INCOME-PRE-EXTRAORDINARY>                  2,954      2,954
<EXTRAORDINARY>                                 0          0
<CHANGES>                                       0          0
<NET-INCOME>                                2,115      2,115
<EPS-BASIC>                                   .35        .35
<EPS-DILUTED>                                 .35        .35
<YIELD-ACTUAL>                               4.51       4.41
<LOANS-NON>                                   242        242
<LOANS-PAST>                                  147        147
<LOANS-TROUBLED>                                0          0
<LOANS-PROBLEM>                                 0          0
<ALLOWANCE-OPEN>                            4,135      4,135
<CHARGE-OFFS>                                  91         91
<RECOVERIES>                                   27         27
<ALLOWANCE-CLOSE>                           4,286      4,286
<ALLOWANCE-DOMESTIC>                        3,273      3,273
<ALLOWANCE-FOREIGN>                             0          0
<ALLOWANCE-UNALLOCATED>                     1,013      1,013