<ARTICLE>                     9
<CIK>                         0000741516
<NAME>                        American National Bankshares Inc.
<MULTIPLIER>                  1000

                                                                             
<PERIOD-TYPE>                                  3-MOS         6-MOS         9-MOS         YEAR
<FISCAL-YEAR-END>                              DEC-31-2000   DEC-31-2000   DEC-31-2000   DEC-31-2000
<PERIOD-START>                                 JAN-01-2000   APR-01-2000   JUL-01-2000   JAN-01-2000
<PERIOD-END>                                   MAR-31-2000   JUN-30-2000   SEP-30-2000   SEP-30-2000
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<INT-BEARING-DEPOSITS>                           1,806           820         3,224         3,224
<FED-FUNDS-SOLD>                                     0             0             0             0
<TRADING-ASSETS>                                     0             0             0             0
<INVESTMENTS-HELD-FOR-SALE>                    127,073       119,467       119,860       119,860
<INVESTMENTS-CARRYING>                          44,035        43,603        43,026        43,026
<INVESTMENTS-MARKET>                            43,142        42,827        42,712        42,712
<LOANS>                                        302,424       318,926       329,775       329,775
<ALLOWANCE>                                      4,286         4,463         4,619         4,619
<TOTAL-ASSETS>                                 504,229       511,062       522,918       522,918
<DEPOSITS>                                     397,061       389,570       408,441       408,441
<SHORT-TERM>                                    24,619        43,665        34,622        34,622
<LIABILITIES-OTHER>                              3,934         2,827         2,816         2,816
<LONG-TERM>                                     21,000        16,000        16,000        16,000
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<PREFERRED>                                          0             0             0             0
<COMMON>                                         6,104         6,104         6,088         6,088
<OTHER-SE>                                      51,511        52,896        54,951        54,951
<TOTAL-LIABILITIES-AND-EQUITY>                 504,229       511,062       522,918       522,918
<INTEREST-LOAN>                                  6,436         6,904         7,326        20,666
<INTEREST-INVEST>                                2,579         2,575         2,501         7,655
<INTEREST-OTHER>                                    52            18            26            96
<INTEREST-TOTAL>                                 9,067         9,497         9,853        28,417
<INTEREST-DEPOSIT>                               3,399         3,480         3,703        10,582
<INTEREST-EXPENSE>                               3,950         4,179         4,527        12,656
<INTEREST-INCOME-NET>                            5,117         5,318         5,326        15,761
<LOAN-LOSSES>                                      215           335           290           840
<SECURITIES-GAINS>                                   0             0             0             0
<EXPENSE-OTHER>                                  3,123         3,097         3,172         9,392
<INCOME-PRETAX>                                  2,954         3,028         3,050         9,032
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<YIELD-ACTUAL>                                    4.51          4.59          4.51          4.54
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