UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                    FORM 10-K

(Mark One)
(X)   Annual  Report  Pursuant  to  Section  13 or 15(d) of the  Securities
      Exchange Act of 1934. For the fiscal year ended December 31, 2001 or

( )   Transition Report Pursuant to Section 13 or 15(d) of the Securities
      Exchange Act of 1934.
      For the transition period from__________ to __________.

                         Commission file number 2-89283

                           IOWA FIRST BANCSHARES CORP.
             ------------------------------------------------------
             (Exact name of registrant as specified in its charter)

    An Iowa Corporation                                   42-1211285
- --------------------------------------------------------------------------------
(State or other jurisdiction of                (I.R.S. Employer incorporation or
        organization)                                 Identification No.)


300 East Second Street, Muscatine, Iowa                      52761
- --------------------------------------------------------------------------------
(Address of principal executive offices)                   (Zip Code)

Registrant's telephone number, including area code   (563) 263-4221
Securities registered pursuant to Section 12(b) of the Act:  None
Securities registered pursuant to Section 12(g) of the Act:  None

Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the  preceding 12 months (or for such  shorter  period that the  registrant  was
required  to file  such  reports),  and  (2) has  been  subject  to such  filing
requirements for the past 90 days.   X    Yes       No
                                    ---        ---

Indicate by check mark if disclosure of delinquent  filers  pursuant to Item 405
of Regulation  S-K is not contained  herein,  and will not be contained,  to the
best of registrant's  knowledge,  in definitive proxy or information  statements
incorporated by reference in Part III of this Form 10-K or any amendment to this
Form 10-K. (X)

The  aggregate  market  value of the voting stock held by  nonaffiliates  of the
registrant as of February 28, 2002,  was  $26,077,823.  As of February 28, 2002,
1,456,404 shares of the Registrant's common stock were outstanding.

Documents incorporated by reference:

Portions of the registrant's  2001 Annual Report are incorporated in Parts I and
II of this Form 10-K.  Portions of the registrant's  Proxy Statement dated March
12, 2002 are incorporated in Part III of this Form 10-K.

The Exhibit Index is located on page 11.



                           ANNUAL REPORT ON FORM 10-K

                                TABLE OF CONTENTS

                                     PART I

                                                                            Page
                                                                             No.

Item  1.  Business
Item  2.  Properties
Item  3.  Legal Proceedings
Item  4.  Submission of Matters to a Vote of Security Holders
Table I.  Executive Officers of the Registrant

                                     PART II

Item  5.  Market for the Registrant's Common Equity and Related
            Stockholder Matters
Item  6.  Selected Financial Data
Item  7.  Management's Discussion and Analysis of Financial Condition
            and Results of Operations
Item  8.  Financial Statements and Supplementary Data
Item  9.  Changes in and Disagreements with Accountants on Accounting
            and Financial Disclosure


                                    PART III

Item 10.  Directors and Executive Officers of the Registrant
Item 11.  Executive Compensation
Item 12.  Security Ownership of Certain Beneficial Owners and Management
Item 13.  Certain Relationships and Related Transactions


                                     PART IV

Item 14.  Exhibits, Financial Statement Schedules, and
            Reports on Form 8-K
            Signatures
            Index of Exhibits



                           ANNUAL REPORT ON FORM 10-K

                                     PART I

ITEM 1. BUSINESS.

Iowa  First  Bancshares  Corp.  (the  "Company"),  is  a  bank  holding  company
headquartered in Muscatine,  Iowa. The Company owns all the outstanding stock of
two national banks in Iowa,  First National Bank of Muscatine and First National
Bank in Fairfield.

On a full-time  equivalent  basis,  year-end  employment for the Company and its
subsidiary banks totaled 125 employees.

First  National  Bank of Muscatine  has a total of five  locations in Muscatine,
Iowa. The First National Bank in Fairfield has two locations in Fairfield, Iowa.
Each bank is engaged in the general  commercial  banking  business  and provides
full service banking to individuals and businesses,  including checking, savings
and other deposit accounts, commercial loans, consumer loans, real estate loans,
safe deposit facilities,  transmitting of funds, trust services,  and such other
banking  services as are usual and customary for commercial  banks.  The Company
also  owns the  outstanding  stock of Iowa  First  Capital  Trust I,  which  was
capitalized  in  March  2001  for  the  purpose  of  issuing  Company  obligated
mandatorily  redeemable preferred securities.  See Footnote 9 on page 29 of this
Form 10-K for further discussion of these preferred securities.

The commercial banking business is highly competitive.  Subsidiary banks compete
with other  commercial  banks and with other financial  institutions,  including
savings banks,  mortgage banking  companies,  credit unions and mutual funds. In
recent years,  competition also has increased from  institutions not necessarily
subject to all the same  regulatory  restrictions  or  requirements as banks and
bank holding companies.

The operations of the Company and its subsidiary banks are affected by state and
federal legislative  changes and by policies of various regulatory  authorities.
The Company is a registered  bank holding company under the Bank Holding Company
Act of 1956 (the "Act") and is subject to the supervision of, and regulation by,
the Board of Governors of the Federal  Reserve System (the  "Board").  Under the
Act, a bank  holding  company  may engage in banking,  managing  or  controlling
banks,  furnishing or performing services for banks it controls,  and conducting
activities that the Board has determined to be closely related to banking.

National  banks are  subject to the  supervision  of, and are  examined  by, the
Office of the Comptroller of the Currency.  Both subsidiary banks of the Company
are members of the  Federal  Deposit  Insurance  Corporation,  and as such,  are
subject to examination thereby. In practice, the primary federal regulator makes
regular examinations of each subsidiary bank subject to its regulatory review or
participates in joint examinations with other federal regulators.  Areas subject
to regulation by these  authorities  include capital  levels,  the allowance for
possible  loan losses,  investments,  loans,  mergers,  issuance of  securities,
payment of  dividends,  establishment  of  branches,  and many other  aspects of
operations.

Statistical  information  called for by this Item is contained in the  Company's
2001 Annual Report to Shareholders  which is incorporated by reference (pages 38
- - 49 of this Form 10-K).

ITEM 2. PROPERTIES.

Since the Company commenced  business,  its principal  executive office has been
located at 300 East  Second  Street,  Muscatine,  Iowa,  which is the  principal
office of First National Bank of Muscatine, a national banking association and a
wholly owned subsidiary of the Company.

First National Bank of Muscatine  conducts its operations  from five  facilities
located in Muscatine.  The main bank is located at 300 East Second Street and is
a modern brick and steel  building  completed in 1979  containing  36,000 square
feet of floor space on three  floors.  The bank owns both the  building  and the
underlying real estate. All  administrative  functions of the bank are conducted
at its main offices.  Portions of the building are leased to commercial tenants.
During  1997,  a branch was  opened  inside  the then new  Wal-Mart  Supercenter
located on highway 61 at  Muscatine.  This branch and the  Wal-Mart  Supercenter
were the first of their kind in Iowa. The bank operates this branch under a five
year  lease  agreement  with  Wal-Mart,  with two  five  year  renewal  options.
Additionally,  another new branch facility, which includes drive-through banking
services  and is  located  across  the  alley  from the main  Muscatine  banking
headquarters, was completed in the fall of 1997. This branch replaced a previous
downtown branch. The bank owns this facility and the underlying real estate.


Two locations,  in addition to the Wal-Mart  branch,  provide  banking  services
outside  the  Muscatine  downtown  area.  The  office at the  Muscatine  Mall is
approximately  two miles  northeast  of the main  bank.  The  facility  contains
approximately 1,500 square feet of floor space in a one-story concrete and steel
building.  The  facility  offers a  walk-in  lobby  and  night  depository.  The
two-lane,  mobile drive-up facility of this branch is located  approximately 100
feet west of the branch at the parking lot of the mall.  The building,  drive-up
facility and real estate are leased. The terms of the leases provide for monthly
payments of $2,465.  These leases are on a month-to-month  basis.  Management is
negotiating  with the new owners of the Muscatine Mall for possible  purchase of
land on which may be erected a freestanding bank branch building.

The  bank's  southside  office  at 608  Grandview  Avenue is  located  two miles
southwest of the main bank. The office contains 3,600 square feet of floor space
and is located in a one-story steel frame, concrete block building. The facility
offers a walk-in lobby and three  drive-up  lanes.  The building and  underlying
real  estate  are owned by the bank.  Portions  of the  building  are  leased to
commercial tenants.

First National Bank in Fairfield conducts its operations from a modern brick and
steel building  completed in 1968 containing 8,200 square feet of floor space on
two floors.  The bank owns both the  building  and the  underlying  real estate.
Portions of the building are leased to commercial tenants. A three-lane drive-up
facility  is  located  at the main  bank.  In the  spring of 1997,  a new branch
facility was opened at Fairfield, Iowa. The building, which is located in a high
traffic  area in front of the  local  Wal-Mart  store on  highway  34,  contains
several  private  offices for lending staff and management as well as teller and
deposit services, including several drive-through lanes.

The Company's  facilities are well maintained and are suitable for the Company's
business operations.

ITEM 3. LEGAL PROCEEDINGS.

The Company has no pending legal proceedings which are material.

ITEM 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS.

None.



                                 PART I, TABLE I
                      EXECUTIVE OFFICERS OF THE REGISTRANT


                              Family                               Position      Business Experience
Name                 Age   Relationship        Position           Held Since     During Past Five Years
- ------------------------------------------------------------------------------------------------------------------------------------
                                                                  
George A. Shepley     79        None      Chairman of the Board      1983        Chairman of the Board, 1983 to
                                          Director                   1983        Present, Chief Executive Officer,
                                                                                 1983 to 2001, President, 1989 to
                                                                                 1996, Iowa First Bancshares Corp.;
                                                                                 Chairman of the Board, 1987 to present, President,
                                                                                 1963 to 1989, First National Bank of Muscatine;
                                                                                 Chairman of the Board, 1986 to
                                                                                 present, First National Bank in
                                                                                 Fairfield.

Kim K. Bartling       44        None      Executive Vice President   1996        Executive Vice President,
                                          Chief Operating Officer    1996        Chief Operating Officer
                                          Treasurer                  1988        and Treasurer of the
                                          Director                   1994        Company, December 1996 to
                                                                                 present;  Senior Vice President,
                                                                                 Chief Financial Officer and Treasurer
                                                                                 of the Company, 1988 to 1996;
                                                                                 Director of the Company
                                                                                 since 1994;  Director of First National Bank of
                                                                                 Muscatine, 1989 to present;
                                                                                 Executive Vice President and
                                                                                 Chief Financial Officer, First
                                                                                 National Bank of Muscatine, 1996 to
                                                                                 present; Senior Vice President/Chief
                                                                                 Financial Officer, First National
                                                                                 Bank of Muscatine, 1987 to
                                                                                 1996; Director First National
                                                                                 Bank in Fairfield, 1990 to present.

D. Scott Ingstad      51        None      Vice Chairman of                       Vice Chairman of the Board,
                                          the Board                  1999        October 1999 to present, Chief
                                          Chief Executive                        Executive Officer, January 2001 to
                                          Officer                    2001        present, Director, 1990 to present,
                                          President                  1996        President, 1996 to present, of the
                                          Director                   1990        Company; Director, President  and  CEO,
                                                                                 1990 to present, Vice Chairman of the Board,
                                                                                 1999 to present, First National Bank of
                                                                                 Muscatine.

Patricia R.           54        None      Secretary                  1986        Corporate Secretary of
Thirtyacre                                                                       the Company, 1986 to present.


                                     PART II

ITEM 5. MARKET FOR THE REGISTRANT'S COMMON EQUITY AND RELATED STOCKHOLDER
        MATTERS

The  brokerage  firms of Howe Barnes  Investments,  Inc.  and Sandler  O'Neill &
Partners, L.P. make a market for the Company's common stock.

High and low common stock prices and dividends paid for the last two years were:

                                                                        Dividend
2001 by Quarters                            High            Low        Per Share
- --------------------------------------------------------------------------------

First ...........................        $   23.75       $   19.13     $   0.22
Second ..........................            22.60           18.88         0.22
Third ...........................            21.75           19.75         0.22
Fourth ..........................            22.50           20.10         0.22

Total Dividend
Paid ............................                                      $   0.88

2000 by Quarters
- --------------------------------------------------------------------------------
First ...........................        $   24.00       $   22.13     $   0.21
Second ..........................            23.00           22.00         0.21
Third ...........................            23.00           18.00         0.21
Fourth ..........................            23.00           18.50         0.21

Total Dividend
Paid ............................                                      $   0.84


The above  quotations were furnished by the brokerage firms that serve as market
makers for the Company's stock. The quotations  represent prices between dealers
and do not include retail markup, markdown, or commissions.

Future dividends are dependent on future earnings,  regulatory restrictions (see
Management's  Discussion  and  Analysis of  Financial  Condition  and Results of
Operations  on pages 38 - 49 of this  Form  10-K;  and Note 10 to the  Company's
Consolidated  Financial  Statements  in the  Company's  2001  Annual  Report  to
Shareholders  which is  incorporated  by  reference,  pages 30 - 31 of this Form
10-K), capital requirements, and the Company's financial condition.

As of February 28, 2002, the Company had  approximately  350 shareholders of its
outstanding  class of common stock.  The Iowa First  Bancshares  Corp.  Employee
Stock Ownership Plan with 401(k) Provisions is considered one shareholder as all
shares owned by this plan are voted by the trustees of said plan unless the vote
in  question  encompasses  approval  or  disapproval  of any  corporate  merger,
consolidation, dissolution, or similar transaction.


ITEM 6. SELECTED FINANCIAL DATA.

The  information  called for by this Item is  contained  in the  Company's  2001
Annual Report to  Shareholders  which is  incorporated  by reference (page 15 of
this Form 10-K).

ITEM 7. MANAGEMENT'S  DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
        OF OPERATIONS.

The  information  called for by this Item is  contained  in the  Company's  2001
Annual Report to Shareholders  which is incorporated by reference (pages 38 - 49
of this Form 10-K).

ITEM 8. FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA.

The  information  called for by this Item is  contained  in the  Company's  2001
Annual Report to Shareholders  which is incorporated by reference (pages 17 - 37
of this Form 10-K).

ITEM  9.  CHANGES  IN AND  DISAGREEMENTS  WITH  ACCOUNTANTS  ON  ACCOUNTING  AND
          FINANCIAL DISCLOSURE.

None.

                                    PART III

           ITEM 10. DIRECTORS AND EXECUTIVE OFFICERS OF THE REGISTRANT

The information called for by this Item is contained in the Company's 2001 Proxy
Statement which is incorporated by reference (page 53 of this Form 10-K).

Director Compensation

The annual retainer that each outside  Director of the Company  received in 2001
was $5,500.  The Company paid $125 for attendance at each committee  meeting and
special Board of Directors  meeting.  During 2001,  each Director of the Company
served  as  Director  and  member  of  committees  for  subsidiary   boards  and
committees,  with the  exception of Mr.  Carver who served only as a Director of
the Company.  The annual retainer fee paid to each outside  subsidiary  Director
was $4,200 to $4,500, plus $75 to $250 for attendance at each committee meeting.
Executive  officers who also serve on the Board of Directors do not receive such
retainer or committee fees.  Additional  information  called for by this Item is
contained  in the  Company's  2001  Proxy  Statement  which is  incorporated  by
reference (pages 54 and 57 of this Form 10-K).

ITEM 11. EXECUTIVE COMPENSATION

The information called for by this Item is contained in the Company's 2001 Proxy
Statement which is incorporated by reference (pages 55 - 57 of this Form 10-K).

ITEM 12. SECURITY OWNERHSIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT.

The information called for by this Item is contained in the Company's 2001 Proxy
Statement  which is  incorporated  by  reference  (pages  52 and 53 of this Form
10-K).


ITEM 13. CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS.

Officers  and  Directors of the Company and its  subsidiaries  have had, and may
have in the future,  banking  transactions in the ordinary course of business of
the Company's subsidiaries.  All such transactions are on substantially the same
terms, including interest rates on loans and collateral,  as those prevailing at
the time for comparable  transactions with others,  and involve no more than the
normal risk of collectibility.

                                    PART IV

ITEM 14. EXHIBITS, FINANCIAL STATEMENT SCHEDULES, AND REPORTS ON FORM 8-K.

         (a)  Documents Filed with This Report:


         (1) Financial   Statements.   The  following   consolidated   financial
             statements of the Company and its  subsidiaries are incorporated by
             reference  from the  2001  Annual  Report  to  Shareholders  of the
             Company:

                                                                            Page
                                                                            ----

         Consolidated balance sheets -- dated December 31, 2001 and 2000.

         Consolidated statements of income -- years ended December 31,
           2001, 2000, and 1999.

         Consolidated statements of changes in stockholders' equity --
           years ended December 31, 2001, 2000, and 1999.

         Consolidated statements of cash flows - years ended
         December 31, 2001, 2000, and 1999.

         Notes to consolidated financial statements.

         Opinion of independent accountants.

         (2) Financial  Statement  Schedules.  All schedules are omitted because
             they are not applicable,  are not required, or because the required
             information  is included in the  financial  statements or the notes
             thereto.

         (b)  Reports on Form 8-K.
              No reports on Form 8-K have been filed  during the last
              quarter of the period covered by this report.

         (c)  Exhibits.
              The  following  exhibits are attached  pursuant to Item 601 of
              Regulation S-K:

              (13)   Registrant's 2001 Annual Report to Shareholders
              (20)   Registrant's Proxy Statement dated March 12, 2002
              (24)   Power of Attorney
              (99)   Audit Committee Charter

See Exhibit Index on page 11 hereof for a complete list of management  contracts
and  arrangements  required  by  this  item  and all  other  Exhibits  filed  or
incorporated by reference as a part of this report.



                                   SIGNATURES

Pursuant to the  requirements of Section 13 or 15(d) of the Securities  Exchange
Act of 1934,  the  registrant  has duly  caused  this report to be signed on its
behalf by the undersigned, thereunto duly authorized.

                                      IOWA FIRST BANCSHARES CORP.

Date:  March 18, 2002                 /s/  George A. Shepley
       --------------                 ----------------------
                                      George A. Shepley
                                      Chairman of the Board

Date:  March 18, 2002                 /s/  Kim K. Bartling
       --------------                 ------------------------------------------
                                      Kim K. Bartling, Executive Vice President,
                                        Chief Operating Officer, Treasurer and
                                        Director (Principal Financial and
                                        Accounting Officer)

We, the undersigned  directors of Iowa First Bancshares  Corp.  hereby severally
constitute  George A. Shepley and Kim Bartling,  and each of them,  our true and
lawful  attorneys  with full power to them, and each of them, to sign for us and
in our name, the capacities  indicated  below, the Annual Report on Form 10-K of
Iowa First  Bancshares  Corp. for the fiscal year ended December 31, 2001, to be
filed herewith and any  amendments to said Annual  Report,  and generally do all
such things in our name and behalf in our capacities as directors to enable Iowa
First Bancshares Corp. to comply with the provisions of the Securities  Exchange
Act of 1934 as amended,  and all  requirements  of the  Securities  and Exchange
Commission, hereby ratifying and confirming our signatures as they may be signed
by our said attorneys, or either of them, to said Annual Report on Form 10-K and
any and all amendments thereto.

Pursuant to the requirements of the Securities Exchange Act of 1934, this report
has been signed below by the following  persons on behalf of the  registrant and
in the capacities and on the dates indicated.

        Signature                Title                               Date
- --------------------------------------------------------------------------------

/s/ Roy J. Carver, Jr.          Director                       February 21, 2002
- ----------------------                                         -----------------
Roy J. Carver, Jr.

/s/ Larry L. Emmert             Director                       February 21, 2002
- ----------------------                                         -----------------
Larry L. Emmert

/s/ Craig R. Foss               Director                       February 21, 2002
- -----------------------                                        -----------------
Craig R. Foss

/s/ Donald R. Heckman           Director                       February 21, 2002
- -----------------------                                        -----------------
Donald R. Heckman

/s/ David R. Housley            Director                       February 21, 2002
- -----------------------                                        -----------------
David R. Housley

/s/ D. Scott Ingstad            Director                       February 21, 2002
- -----------------------                                        -----------------
D. Scott Ingstad

/s/ Victor G. McAvoy            Director                       February 21, 2002
- -----------------------                                        -----------------
Victor G. McAvoy

/s/ John "Jay" S. McKee         Director                       February 21, 2002
- -----------------------                                        -----------------
John "Jay" S. McKee

/s/ Beverly J. White            Director                       February 21, 2002
- -----------------------                                        -----------------
Beverly J. White






                       ITEM 14 (a) (3) - INDEX OF EXHIBITS

Exhibit                                                                Page
                                                
(3)    Articles of Incorporation, as amended       Incorporated by reference to Exhibit
                                                   (3) to the registrant's Annual Report
                                                   on Form 10-K for the fiscal year ended
                                                   December 31, 1996.

(10a)  Employment Agreement                        Incorporated by reference to Exhibit
                                                   (10a) to the registrant's
                                                   Annual Report on Form 10-K
                                                   for the fiscal year ended
                                                   December 31, 1995.

(10b)  Change in Control Employment Agreement      Incorporated by reference to Exhibit
                                                   (10b) to the registrant's
                                                   Annual Report on Form 10-K
                                                   for the fiscal year ended
                                                   December 31, 1995.

(10c)  Executive Deferred Compensation Agreement   Incorporated by reference to Exhibit
                                                   (10c)  to the registrant's
                                                   Annual Report on Form 10-K
                                                   for the fiscal year ended
                                                   December 31, 2000.

(10d)  Director Deferred Fee Agreement             Incorporated by reference to Exhibit
                                                   (10d) to the registrant's Annual
                                                   Report on Form 10-K for the
                                                   fiscal year ended December 31, 2000.

(13)   Registrant's 2001 Annual Report to
         Shareholders

(20)   Registrant's Proxy Statement Dated
         March 12, 2002

(21)   Subsidiaries of Registrant                  Incorporated by reference to Exhibit 21
                                                   to the registrant's Annual Report on Form 10-K
                                                   for the fiscal year ended  December 31, 1995.

(24)   Power of Attorney


(99)   Audit Committee Charter