Exhibit 32.1


                            CERTIFICATION PURSUANT TO
                             18 U.S.C. SECTION 1350,
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Quarterly Report of QCR Holdings, Inc. (the "Company") on
Form 10-Q for the period ending  September 30, 2006 as filed with the Securities
and  Exchange  Commission  on the date  hereof  (the  "Report),  I,  Douglas  M.
Hultquist,  Chief  Executive  Officer of the  Company,  certify,  pursuant to 18
U.S.C.  ss. 1350, as adopted  pursuant to ss. 906 of the  Sarbanes-Oxley  Act of
2002, that:

     (1)  The Report fully  complies with the  requirements  of section 13(a) or
          15(d) of the Securities Exchange Act of 1934; and

     (2)  The  information  contained  in the  Report  fairly  presents,  in all
          material respects, the financial condition and result of operations of
          the Company.


/s/  Douglas M. Hultquist
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Douglas M. Hultquist
Chief Executive Officer
November 9, 2006